Abstract：
OBJECTIVE:To study the density of nerve fibers in cases of deep infiltrating endometriosis (DIE) of the rectovaginal septum in relation to various clinical factors. DESIGN:A research laboratory-based study. SETTING:A tertiary center together with a research laboratory. METHODS:Archived DIE tissue samples from 45 women operated upon for rectovaginal septum DIE were re-examined histologically, and by immunohistochemistry. MAIN OUTCOME MEASURES:The effect of progestogens or combined oral contraceptives on the density of nerve fibers, and the expression of nerve growth factor (NGF) and its high-affinity receptor (tyrosine kinase receptor A, Trk-A). RESULTS:The use of hormonal therapy was associated with reduced densities of sympathetic, parasympathetic and sensory nerve fibers in DIE lesions. Density of total nerve fibers (with pan-neuronal marker PGP9.5) was significantly lower (p < 0.05) in lesions collected from hormone-treated women (8.6/mm², 4.2-20.8/mm²; median density, from 25th to 75th quartiles) compared with that in lesions from untreated women (24.9/mm², 11.2-34.9/mm²). DIE lesions stained strongly for NGF and its receptor Trk-A. Expression of NGF, but not of Trk-A, was significantly reduced during use of hormonal therapy. CONCLUSIONS:Use of hormonal therapy was associated with significantly reduced nerve fiber density in DIE lesions. This may be an important mechanism of action of hormonal therapy for controlling DIE pain symptoms. The expression of estrogen-regulated NGF and its receptor was only partially suppressed during the use of hormonal therapy, suggesting that local estrogen action is often maintained during conventional hormonal therapy in cases of DIE.
journal_name
Acta Obstet Gynecol Scandjournal_title
Acta obstetricia et gynecologica Scandinavicaauthors
Tarjanne S,Ng CHM,Manconi F,Arola J,Mentula M,Maneck B,Fraser IS,Heikinheimo Odoi
10.1111/aogs.12652subject
Has Abstractpub_date
2015-07-01 00:00:00pages
693-700issue
7eissn
0001-6349issn
1600-0412journal_volume
94pub_type
杂志文章abstract：:Blood samples from pregnant women and from mothers before and after delivery were tested for the occurrence of feto-maternal bleeding (f.m.b.) using Kleihauers acid-elution technique and a counting technique described by Schneider. It was assumed that f.m.b. had occurred, when there was a clinically significant differ...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016347709155017
更新日期：1977-01-01 00:00:00
abstract：INTRODUCTION:The aim of this study was to investigate the differences in shear-wave sonoelastography (SWS) scores between the different parts of cervix, explore the association between the cervical SWS scores with cervical length and evaluate repeatability of the measurement of cervical SWS scores. MATERIAL AND METHOD...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 临床试验,杂志文章
doi：10.1111/aogs.13874
更新日期：2020-11-01 00:00:00
abstract：BACKGROUND:To improve the diagnostic accuracy of concurrent renal disease in hypertension of pregnancy, biopsy evaluation is essential. In addition, establishing underlying renal disease is important for prognosis on future pregnancies. We therefore designed a study to determine the diagnostic yield of postpartum renal...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：
更新日期：2000-05-01 00:00:00
abstract：OBJECTIVE:Although Norplant implantable contraceptives were introduced first in Finland, their use has been infrequent. The objective of this study was to investigate what kind of women use Norplant in Finland, who suggested its use, and from what source women get their information on Norplant. METHODS:A questionnaire...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016349409013435
更新日期：1994-07-01 00:00:00
abstract：BACKGROUND:The aim was to describe the short- and long-term results of treatment for urinary incontinence (UI) in women using the tension-free vaginal tape (TVT) procedure at a single unit and to identify factors predictive of successful outcome. MATERIAL AND METHODS:Consecutive female patients (n = 707) treated for U...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.1080/00016340600753091
更新日期：2006-01-01 00:00:00
abstract：INTRODUCTION:Pregnancy after liver transplantation is possible but associated with increased risk of obstetrical complications. We report here for the first time the pregnancy outcomes after liver transplantation in Finland. MATERIAL AND METHODS:All of the 25 pregnancies ending in deliveries after liver transplantatio...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.1111/aogs.13175
更新日期：2017-09-01 00:00:00
abstract：:An analysis of 230 patients treated with radiotherapy for cervical cancer stages I and II is presented. No positive correlation to cell type was found as regards the number of failures, recurrence rate or the frequency of regional or distant metastases. Although different biological behavior might be shown by cancers ...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016347609156923
更新日期：1976-01-01 00:00:00
abstract：OBJECTIVE:Neuralgic pain caused by entrapment of peripheral nerves can be a difficult clinical problem. The objective of the present study was to assess pain and quality of life in women with pain secondary to ilioinguinal nerve entrapment. DESIGN:In a controlled prospective crossover study, women with ilioinguinal ne...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章,随机对照试验
doi：10.1111/j.1600-0412.2011.01194.x
更新日期：2011-09-01 00:00:00
abstract：OBJECTIVE:To investigate the frequency of lumbosacral pains and sacroiliitis as late sequela of severe pelvic inflammatory disease (PID) confirmed by laparoscopy or laparotomy. DESIGN:The sacroiliac joints were examined radiographically and scintigraphically to search for signs of reactive sacroiliitis. SETTING:Depar...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016349409015772
更新日期：1994-04-01 00:00:00
abstract：INTRODUCTION:Accurate estimates and reliable classification of maternal deaths are imperative steps in the chain of actions targeted at reducing avoidable maternal mortality. The aims of this study were to estimate the maternal mortality ratio (MMR) in 10 Italian regions covering 77% of total national births and to ide...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.1111/aogs.13415
更新日期：2018-11-01 00:00:00
abstract：OBJECTIVE:To assess trends for hysterectomy methods in the Nordic countries and to compare outcomes of hysterectomies in Finland done by trainees with those done by specialists. DESIGN:Register-based study. SETTING:NOMESCO database for the Nordic countries and the Finnish Hospital Discharge Register. POPULATION:Nati...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.1111/aogs.12654
更新日期：2015-07-01 00:00:00
abstract：OBJECTIVE:To determine the performance of trained midwives in second trimester ultrasound screening for fetal structural abnormalities in a low-risk population. DESIGN:Retrospective study. SETTING:University Department of Obstetrics and Gynecology. POPULATION:About 13,882 women with singleton pregnancies. METHODS:T...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.1080/00016340902934688
更新日期：2009-01-01 00:00:00
abstract：OBJECTIVE:To compare the efficacy, feasibility and morbidity of two preparation techniques for conservative uterine myoma surgery: temporary embolization and temporary surgical ligature of the uterine arteries. DESIGN:Retrospective study. SETTING:Gynecological Surgery and Interventional Radiology departments, Centre ...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016349.2010.512060
更新日期：2010-10-01 00:00:00
abstract：OBJECTIVES:to evaluate the additional information of second trimester magnetic resonance imaging (MRI) compared to ultrasound in fetuses with identified or suspected central nervous system (CNS) anomalies and to study the clinical impact of the information on pregnancy management. DESIGN:prospective study during 2004-...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016349.2010.526184
更新日期：2010-12-01 00:00:00
abstract：BACKGROUND:Little is published about obstetrical problems after treatment of cervical intraepithelial neoplasia with the C02-laser. The aim of this study was to determine the risk of low birth weight in the subsequent pregnancy after laser conization or vaporization in a follow-up study of women treated for cervical in...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016349609033306
更新日期：1996-02-01 00:00:00
abstract：BACKGROUND:Amniotic fluid contains a significant level of urinary trypsin inhibitor (UTI). Previously, we reported that UTI inhibits calcium influx of myometrium and it is effective in preventing uterine contraction. This study examined the effects of UTI upon potassium channels, which is important for membrane excitab...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0412.2004.00268.x
更新日期：2004-01-01 00:00:00
abstract：OBJECTIVE:To evaluate the risk of severe acute maternal morbidity (SAMM) related to mode of delivery. DESIGN:Prospectively nationwide population based cohort study. Setting. All 98 maternity units in the Netherlands. POPULATION:All pregnant women in the Netherlands. METHODS:Cases were collected during a 2-year perio...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016349.2010.519018
更新日期：2010-11-01 00:00:00
abstract：BACKGROUND:Maternal symptoms such as severe headache, nausea and vomiting, visual disturbances and epigastric pain have been associated with complications in women with preeclampsia. OBJECTIVE:To determine the accuracy of maternal symptoms in predicting complications in women with preeclampsia by systematic review. D...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章,meta分析,评审
doi：10.1111/j.1600-0412.2011.01111.x
更新日期：2011-06-01 00:00:00
abstract：:In this prospective study, 56 women (2.3%) of 2,358 (47% nulliparous and 53% multiparous) delivered during a 12-month period at the Department of Obstetrics and Gynecology, Malmö General Hospital, had symptoms of carpal tunnel syndrome during pregnancy. All (33 nulliparous and 23 multiparous women) were examined, at t...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016348709020753
更新日期：1987-01-01 00:00:00
abstract：OBJECTIVE:Hypomagnesemia is associated with diabetes mellitus type 2 and other components of the metabolic syndrome in older patients. Whether serum magnesium concentrations correlate with insulin resistance, obesity, hypertension, dyslipidemia, or other components of metabolic syndrome in younger women with polycystic...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0412.2010.01067.x
更新日期：2011-05-01 00:00:00
abstract：BACKGROUND:Both the estrogen receptor (ER) alpha and beta isoforms are expressed in the endothelium. The ER beta has been assigned a crucial role in normal vascular wall function. Prostacyclin has been ascribed a beneficial effect on vessel wall physiology. Isoflavones bind with higher affinity to ER beta. We investiga...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 临床试验,杂志文章
doi：10.1080/j.1600-0412.2003.00178.x
更新日期：2003-08-01 00:00:00
abstract：:Minor degrees of endometriosis have often been regarded as being of no import and hence remain untreated, but a study of the natural history of endometriosis has demonstrated that 47% (95% confidence limits, 23-71%) of patients (n=35) given placebo in a double-blind, randomized controlled trial showed progression of t...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.1111/aogs.1989.68.s150.27
更新日期：1989-01-01 00:00:00
abstract：:We treated five patients with stenosing lichen planus [LP] of the vulvovaginal region with methotrexate supplemented with ultrapotent corticosteroid cream and tacrolimus, in combination with surgical dilatation. All patients experienced long-term symptom relief, and there was only minimal or moderate re-stenosing of t...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.1080/00016340601110721
更新日期：2007-01-01 00:00:00
abstract：:Identification of poor fetal growth is an important objective of antenatal care. We evaluated the validity of the Wennergren score to predict small for gestational age and/or underweight for length infants (low ponderal index). To 405 randomly chosen pregnant women from our university hospital population, this numeric...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016348909006141
更新日期：1989-01-01 00:00:00
abstract：:We determined the effect of cord blood collection before placental expulsion on postpartum maternal blood loss in a retrospective study between a group of cord blood donors and a group of non-donors. The study was conducted in a university hospital blood bank and obstetric services and included Spanish women entered i...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0412.2011.01182.x
更新日期：2011-09-01 00:00:00
abstract：:The concentrations of FSH, LH, 17-beta-estradiol (E2), estrone (E1) and progesterone (P) were measured in peripheral and ovarian vein sera obtained at preoperative pelvic angiography from 5 postmenopausal women with malignant ovarian tumors. In 5 others the concentrations of E2, P and testosterone (T) were also measur...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016348609155172
更新日期：1986-01-01 00:00:00
abstract：BACKGROUND:Secondhand smoke (SHS) exposure harms pregnant women and the fetus. China has the world's largest number of smokers and a high male smoking prevalence rate. OBJECTIVE:To compare exposure to SHS among rural and urban Chinese non-smoking pregnant women with smoking husbands, and analyze factors associated wit...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016341003713851
更新日期：2010-01-01 00:00:00
abstract：INTRODUCTION:Women with endometriosis have reduced health-related quality of life (HRQoL). However, comparisons to the general population and other patient groups are lacking. MATERIAL AND METHODS:The present cross-sectional questionnaire study included 157 women with endometriosis, 156 women from the general populati...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.1111/aogs.13427
更新日期：2018-11-01 00:00:00
abstract：:Three cases of pseudomyxoma peritonei with ovarian neoplasma were treated by adjunctive immunotherapy with OK-432 after surgery. In 2 of the 3 cases, the periods of intramuscular injection of OK-432 were 11 and 16 months, respectively, and the 2 patients remain clinically free from evidence of disease, 7 and 6 years a...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016348609158368
更新日期：1986-01-01 00:00:00
abstract：:We studied vaginal erotic sensitivity by vaginal sexological examinations as part of the evaluation and treatment process of couples complaining of female coital anorgasmia but readily orgasmic at female self--or partner-performed external genital stimulation. The existence on the anterior vaginal wall of an anatomica...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016348609161498
更新日期：1986-01-01 00:00:00
