Abstract：
:Minor degrees of endometriosis have often been regarded as being of no import and hence remain untreated, but a study of the natural history of endometriosis has demonstrated that 47% (95% confidence limits, 23-71%) of patients (n=35) given placebo in a double-blind, randomized controlled trial showed progression of the disease when assessed before and after treatment by laparoscopy. The active agent, the progestogen gestrinone, was given at a dose of 2.5 mg twice weekly and resulted in an improvement of the disease (p <0.004). Furthermore, follow-up over 12 months showed no significant difference between those patients treated with active agent or placebo, and none between those with persistent disease and those in whom it had been obliterated. These data suggest that a diagnosis of mild endometriosis should be followed by treatment to prevent progressive disease, but that the treatment does not influence subsequent fertility. They indicate that expectant treatment has no place and that even if fertility is not an immediate requirement, active treatment should be instituted, and that the new gestogen, gestrinone is efficacious. Other treatments, such as danazol or luteinizing hormone releasing hormone (LHRH) agonists, or the older contraceptive or pseudopregnancy regimens, must be set against spontaneous improvement (in 5 of 17 patients i.e. 29%) or elimination (in 4 of 17 patients i.e. 24%) in the placebo group. Infertile patients with mild endometriosis have disorders of follicular and luteal function, and in vitro fertilization suggests a reduced fertilization rate. Nevertheless, these patients require active treatment if these problems are not to be compounded by adhesions, possibly leading to ovarian enclosure, that would further reduce the untreated cumulative conception rate.
journal_name
Acta Obstet Gynecol Scandjournal_title
Acta obstetricia et gynecologica Scandinavicaauthors
Cooke ID,Thomas EJdoi
10.1111/aogs.1989.68.s150.27subject
Has Abstractpub_date
1989-01-01 00:00:00pages
27-30issue
S150eissn
0001-6349issn
1600-0412journal_volume
68pub_type
杂志文章abstract：:A model of prospective counselling and intervention after prenatal diagnosis of fetal malformation is presented. 13 patients/couples with severe malformations were fully counselled, 3 patients/couples interviewed post-termination. Objectives of the counselling strategy were to support patient autonomy, facilitate mour...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016348909028667
更新日期：1989-01-01 00:00:00
abstract：:Continuous monitoring of the fetal scalp tissue pH (tpH) was performed in 96 consecutive cases. Of these 96, 72 (75%) had acceptable pH tracings which were used for the management of labor (series II). These 72 patients were compared with 72 patients from an earlier series (series I) of tpH monitoring in which pH was ...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：
更新日期：1982-01-01 00:00:00
abstract：INTRODUCTION:Fetal growth restriction (FGR) is associated with poor perinatal outcomes. Screening and prevention tools for FGR, such as uterine artery Doppler imaging and aspirin, underperform in high-risk groups, compared with general antenatal populations. There is a paucity of sensitive screening tests for the early...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.1111/aogs.12823
更新日期：2016-03-01 00:00:00
abstract：:Tumors of the fallopian tube are extremely rare. A case of a papilloma occluding the right fallopian tube of a woman with primary sterility is reported. ...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016348809004177
更新日期：1988-01-01 00:00:00
abstract：:A 50-year-old women was admitted on suspicion of abdominal tumor. Clinical examination and ultrasonography revealed a living fetus of 24.2 weeks' gestational age. Amniocentesis revealed trisomy 18 (Edwards' syndrome). At 34 weeks the fetus died spontaneously, and by cesarean section a stillborn boy of 770 g was delive...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：
更新日期：1988-01-01 00:00:00
abstract：:A fetal tibia was removed from the uterus of a woman who had had a legal abortion 8 years earlier, followed by tubal sterilization. Because of irregular vaginal bleeding she was hysterectomized and no sign of recanalization of the Fallopian tubes was seen peroperatively. ...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016348609157363
更新日期：1986-01-01 00:00:00
abstract：OBJECTIVE:Currently, no prospective study supports or refutes the value of secondary cytoreductive surgery in patients with ovarian cancer. We therefore reviewed the surgical data of patients who underwent second-look laparotomy (SLL) with or without secondary cytoreductive surgery at our department. METHODS:Analysis ...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：
更新日期：2001-05-01 00:00:00
abstract：AIMS:To examine per- and postoperative complication rates and efficacy of laser conization in the treatment of cervical intraepithelial neoplasia (CIN) grade II-III. MATERIAL AND METHODS:Eligible for analyses were all women treated with their first laser conization because of CIN II-III during the time-period January ...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：
更新日期：1998-05-01 00:00:00
abstract：:By using DNA cytofluorometry, DNA ploidy and the distribution pattern of human trophoblasts at different sites were studied throughout pregnancy, and the proliferative activity during cell differentiation of trophoblasts was discussed. In the first and second trimesters, cytofluorometric nuclear DNA analysis demonstra...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016349209007940
更新日期：1992-01-01 00:00:00
abstract：:A 54-year-old postmenopausal woman is described who quite suddenly experienced intense tenderness and tension in both breasts lasting for about 3 weeks. Subsequently she had a uterine bleeding. Excessively increased levels of estradiol (peak value 2325 pmol/l) were found during the period of mastodynia. Seven months p...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016348509156738
更新日期：1985-01-01 00:00:00
abstract：OBJECTIVE:External cephalic version (ECV) is a safe and effective intervention that can prevent breech delivery, thus reducing the need for cesarean delivery. It is recommended in national guidelines. These guidelines also mention contraindications for ECV, and thereby restrict the application of ECV. We assessed wheth...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章,评审
doi：10.1111/aogs.12011
更新日期：2013-02-01 00:00:00
abstract：:The objective of this study was to assess the cost-effectiveness of hysterectomy performed for benign indications. Hysterectomy remains the most common major gynecological operation in the Western world. Rates of hysterectomy have not declined as expected with the introduction of new treatment options. Furthermore, us...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章,评审
doi：10.1111/aogs.12299
更新日期：2014-03-01 00:00:00
abstract：BACKGROUND:To investigate the role of interleukin-1 related substances in amniotic fluid in normal term labor without intrauterine infection. METHODS:Amniotic fluid samples were collected from forty-one patients with various backgrounds. A novel pre-assay treatment using Frigen II was introduced to improve the recover...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：
更新日期：1999-04-01 00:00:00
abstract：INTRODUCTION:The aim of this study was to compare the efficacy and maternal-neonatal morbidity between balloon catheter and oxytocin for induction of labor in women with a previous cesarean section and an unfavorable cervix. MATERIAL AND METHODS:This open-label randomized controlled trial took place in seven French ho...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1111/aogs.13712
更新日期：2020-02-01 00:00:00
abstract：OBJECTIVE:To show that early discontinuation of oxytocin will not increase the mean duration of the active labor phase in a clinically significant way. DESIGN:Controlled non-inferiority study. SETTING:Department of Obstetrics and Gynecology, University of Caen, Clemenceau Hospital, France. POPULATION:A total of 138 ...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.1080/00016340802649816
更新日期：2009-01-01 00:00:00
abstract：INTRODUCTION:Many studies have shown that multifetal reduction of high-order multiple pregnancies results in improved pregnancy outcomes. However, whether conducting elective fetal reduction from dichorionic twins after in vitro fertilization (IVF) is worthwhile remains controversial. This study aimed to determine whet...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.1111/aogs.13640
更新日期：2019-10-01 00:00:00
abstract：OBJECTIVE:To determine the false negative rate of a sterile speculum examination for the diagnosis of rupture of the membranes in women not in labor and without visible amniotic fluid at speculum examination. Furthermore, possible risks to the mother and the baby after suspected rupture of the membranes were analyzed. ...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016349709024339
更新日期：1997-09-01 00:00:00
abstract：:Sciatic pain in a young woman was not relieved by orthopedic treatment. The gynecologist found a large hard tumor-like mass in the uterosacral ligament extending to the pelvic wall. Cytologic examination of fine needle aspirate indicated an endometriotic lesion. The large tumor-like mass was extirpated by an extraperi...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016348709092967
更新日期：1987-01-01 00:00:00
abstract：BACKGROUND:The objective of the study was to assess the relationship between maternal smoking habits and biomarkers of tobacco smoke measured in cord serum. METHODS:The study population comprised 202 mothers, 42 daily smokers, 24 occasional smokers and 136 nonsmokers. Information on maternal smoking habits was collect...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016349609055025
更新日期：1996-11-01 00:00:00
abstract：:In a study of 1,955 primigravidae who gave birth to a live singleton baby, 227 (11.6%) scored 'positive' (7+) in an antenatal Health Questionnaire enquiring into pre-pregnancy emotional disturbances. This group of mothers had more frequent depression, and this was of longer duration after their delivery compared with ...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016348809004190
更新日期：1988-01-01 00:00:00
abstract：INTRODUCTION:Approximately 85% of vaginal deliveries are accompanied by perineal trauma. The objective of this trial was to compare the incidence of perineal trauma after primary delivery of either the anterior or posterior shoulder during vaginal delivery. MATERIAL AND METHODS:This was a randomized single-blinded tri...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章,随机对照试验
doi：10.1111/aogs.12914
更新日期：2016-09-01 00:00:00
abstract：:We generated five murine monoclonal antibodies reactive with ovarian cancer-associated antigen CA125. These monoclonal antibodies seemed to bind to separate epitopes from OC125 antibody, known to recognize CA125. A series of immunoradiometric assays for measuring serum CA125 values rapidly and sensitively were devised...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016349009006164
更新日期：1990-01-01 00:00:00
abstract：:Congenital granular cell myoblastoma of the newborn is a rare tumor. The combination of polyhydramnios caused by obstruction of the infant's mouth by this tumor is extremely rare, and this is the first published report of such a condition. ...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016348609157400
更新日期：1986-01-01 00:00:00
abstract：:Patients with FIGO stage IA1 squamous cell carcinoma of the cervix can be treated conservatively with simple hysterectomy or, if young and desiring to preserve their fertility, with conization only, provided surgical margins are free of dysplasia or invasive disease. When the surgical margins are involved a repeat con...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章,评审
doi：10.1034/j.1600-0412.2003.00124.x
更新日期：2003-06-01 00:00:00
abstract：OBJECTIVE:To study the neuroendocrine release of cortisol in response to perceived stress among pregnant women exposed to partner violence and how this affects the duration of pregnancy and the intrauterine growth of the infant. DESIGN:Cross-sectional community-based study. SETTING:Health and Demographic Surveillance...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.1080/00016340903015321
更新日期：2009-01-01 00:00:00
abstract：BACKGROUND:To study the incidence of non-gonococcal salpingitis, gonococcal salpingitis and ectopic pregnancy in a defined population over a 28-year period on the assumption that the frequency of salpingitis and ectopic pregnancy may indirectly illustrate the epidemiological pattern of Chlamydia trachomatis. DESIGN:A ...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.1034/j.1600-0412.2000.079002123.x
更新日期：2000-02-01 00:00:00
abstract：OBJECTIVES:To evaluate the accuracy of different preoperative modalities for staging of endometrial cancer to restrict extensive surgery to patients at high risk of metastatic disease. SETTING:Aarhus University Hospital. POPULATION:156 women referred in 2006-2011 because of atypical endometrial hyperplasia (G0) or en...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.1111/aogs.12103
更新日期：2013-05-01 00:00:00
abstract：OBJECTIVE:To study the predictive value of biphasic ST-events for interventions for suspected fetal distress and adverse neonatal outcome, when using ST-analysis of the fetal electrocardiogram (FECG) for intrapartum fetal monitoring. DESIGN:Prospective cohort study. SETTING:Three academic hospitals in Sweden. POPULA...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章,随机对照试验
doi：10.1111/aogs.12548
更新日期：2015-02-01 00:00:00
abstract：BACKGROUND:There is a lack of established treatment for Chronic pelvic pain (CPP), defined as acyclic pain of at least six months duration. We decided to study the pain-alleviating effects of stretching on defined structures in women with CPP, and the treatment's impact on quality of life variables. DESIGN OF STUDY:An...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章,随机对照试验
doi：10.1080/00016340500495017
更新日期：2006-01-01 00:00:00
abstract：OBJECTIVE:To investigate risk factors associated with postterm pregnancy and cesarean delivery following labor induction. DESIGN:Population-based cohort study. SETTING:Sweden. POPULATION:From the Swedish Medical Birth Register, a total of 1,176,131 singletons births from gestational week 37 and onwards, between 1992...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016349.2010.500009
更新日期：2010-08-01 00:00:00
