Postovulatory endometrial development in women with I.U.D.

Abstract:

:Researchers in Copenhagen, Denmark conducted a study to determine if an IUD in a normal woman retards endometrial development. 14 Lippes loop users and 14 controls were studied. The device users had had their IUDs inserted at least 1 year previously and menstruated regularly. The basal temperature curve determined the time of ovulation. Retardation was found in all of the IUD cases and ranged from .5-4.5 days; it exceeded 2 days in 5 cases. Retardation was significantly greater (pL.001) in the IUD group than in the control group. Endometrial biopsy specimens from IUD women from a stage prior to the development of a normal pseudodecidual reaction showed foci with large, decidua-like cells with PAS-positive cyto- plasm. These cells may be responsible for the secretion of an endometrial retarding factor. Though endometrial retardation may well be 1 of the causes of the IUD's contraceptive effect, this relatively small series allows no extensive conclusions.

authors

Nicolaisen HH,Pedersen H,Guttorm E,Rebbe H

doi

10.3109/00016347309158323

subject

Has Abstract

pub_date

1973-01-01 00:00:00

pages

253-8

issue

3

eissn

0001-6349

issn

1600-0412

journal_volume

52

pub_type

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