Diagnosis and treatment of submucous myoma of the uterus with interventional ultrasound.

abstract：:Lin28 is involved in the progression of several types of tumors. Data collected from clinical trials have suggested that Lin28 expression is correlated with poor prognosis in thyroid carcinoma. The present study was conducted to investigate the association between Lin28 expression and the clinicopathological parameter...

journal_title：Oncology letters

authors： Jin S,Xu C,Wang L,Wei J,Wang S

更新日期：2021-02-01 00:00:00

abstract：:We report a case of tumor lysis syndrome (TLS) in a patient with gallbladder carcinoma. TLS has not been reported in association with this type of tumor. TLS typically occurs in cases of highly proliferative hematological malignancies and small cell carcinoma. Two factors that may have contributed to TLS in this case ...

journal_title：Oncology letters

authors： Duff DJ,Haddadin S,Freter C,Papageorgiou C

更新日期：2013-04-01 00:00:00

abstract：:In the present study, the anti-tumor effects of combination treatment with an siRNA targeting B-Raf proto-oncogene serine/threonine kinase (BRAF)V600E and phosphoinositide 3-kinase (PI3K) signaling pathway inhibitors was investigated in melanoma cell lines harboring BRAFV600E. Human melanoma A375 and WM115 cells were ...

journal_title：Oncology letters

authors： He H,Nan X,Liu S,Zhang L,Yang Z,Wu Y,Zhang L

更新日期：2018-07-01 00:00:00

abstract：:Patients with renal medullary carcinoma (RMC) have a poor prognosis, usually due to late diagnosis. Computed tomography (CT) analysis may aid the differentiation between RMC and other types of renal cell carcinoma, in order to establish an accurate early diagnosis. There is a limited number of reports in the literatur...

journal_title：Oncology letters

authors： Shi Z,Zhuang Q,You R,Li Y,Li J,Cao D

更新日期：2016-01-01 00:00:00

abstract：:Acanthus ebracteatus Vahl. is commonly consumed with the aim of curing cancer, inflammatory conditions and skin diseases in traditional Thai medicine. It is known to contain various phytochemicals; however, very little is known about the effects of A. ebracteatus protein hydrolysate on cancer cells, including its mole...

journal_title：Oncology letters

authors： Khamwut A,Jevapatarakul D,Reamtong O,T-Thienprasert NP

更新日期：2019-09-01 00:00:00

abstract：:Observational and experimental studies have produced inconsistent evidence about the association of serum levels of B-type natriuretic peptide (BNP) with anthracycline-induced cardiotoxicity (AIC). Therefore, the current meta-analysis examined the association between serum BNP levels and AIC by using data from high qu...

journal_title：Oncology letters

authors： Wang YD,Chen SX,Ren LQ

更新日期：2016-05-01 00:00:00

abstract：:Effects of Rapamycin on the proliferation and apoptosis of retinoblastoma cells through the phosphatidylinositol 3-hydroxy kinase (PI3K)/protein kinase B (AKT) signaling pathway were studied. The retinoblastoma Y79 cells were selected and divided into negative control group (NC group), 0.2 µM Rapamycin group and 0.4 µ...

journal_title：Oncology letters

authors： Yao J,Xu M,Liu Z

更新日期：2020-04-01 00:00:00

abstract：:The medicinal mushroom Ganoderma lucidum (G. lucidum) has been used for the treatment of various diseases, and is known for the immune-enhancing activity of its polysaccharide. However, little is known about another of its major constituents, triterpene. This study investigated the anticancer mechanism of a triterpene...

journal_title：Oncology letters

authors： Ji Z,Tang Q,Hao R,Zhang J,Pan Y

更新日期：2011-05-01 00:00:00

abstract：:Despite all efforts at management, prognosis of advanced lung cancer is extremely poor, with a median survival time of ~1 year. The number of cancer patients aged >70 years is significantly increased among the cancer patient population. The aim of this study was to investigate the clinical importance of age in lung ca...

journal_title：Oncology letters

authors： Tas F,Ciftci R,Kilic L,Karabulut S

更新日期：2013-11-01 00:00:00

abstract：:Terrein is a bioactive fungal metabolite isolated from Aspergillus terreus. Besides being a melanogenesis inhibitor, previous studies have revealed that terrein has antiproliferative effects on a number of types of cancer tumors. In the present study, the inhibitory effect of terrein on esophageal cancer was evaluated...

journal_title：Oncology letters

authors： Wu Y,Zhu Y,Li S,Zeng M,Chu J,Hu P,Li J,Guo Q,Lv XB,Huang G

更新日期：2017-04-01 00:00:00

abstract：:The aims of this study were to determine the methylation and expression status of secreted Frizzled-related protein 1 (SFRP1) in bladder cancer, to explore the mechanisms involved and to study the role of SFRP1 in the pathogenesis of bladder cancer. SFRP1 mRNA was detected by reverse transcription PCR (RT-PCR). The DN...

journal_title：Oncology letters

authors： Wang X,Wang H,Bu R,Fei X,Zhao C,Song Y

更新日期：2012-08-01 00:00:00

abstract：:The anticancer effect of Scutellaria baicalensis extract has recently become a topic of interest. In this study, the anticancer effects and underlying mechanisms of wogonoside, the main constituent of Scutellaria baicalensis, were investigated in a human hepatocellular carcinoma (HCC) cell line in vitro. The effects o...

journal_title：Oncology letters

authors： Li Y,Tu M,Cheng C,Tian J,Zhang F,Deng Z,Li X,Li Z,Liu Y,Lei G

更新日期：2015-09-01 00:00:00

abstract：:Poor nutritional status is common in ovarian cancer. It is well known that the nutritional status of a patient with malignant disease is associated with survival, and that it can be assessed by serum levels of rapid turnover proteins (RTPs), such as retinol binding protein, prealbumin and transferrin. Systemic inflamm...

journal_title：Oncology letters

authors： Watanabe T,Shibata M,Nishiyama H,Soeda S,Furukawa S,Gonda K,Takenoshita S,Fujimori K

更新日期：2014-02-01 00:00:00

abstract：:There is a growing body of evidence indicating that several melanoma-associated antigen-A (MAGE-A) subgroups contribute to the malignancy of head and neck cancer. The present study retrospectively analyzed the expression of all known MAGE-A subgroups in the tumor front and center of 38 head and neck cancer patients (U...

journal_title：Oncology letters

authors： Hartmann S,Brisam M,Rauthe S,Driemel O,Brands RC,Rosenwald A,Kübler AC,Müller-Richter UD

更新日期：2016-10-01 00:00:00

abstract：:MicroRNAs (miRs) are a group of short, endogenous, non-protein-coding and single-stranded RNAs that regulate gene expression by binding to the 3'-untranslated region (3'UTR) of mRNAs, which results in their degradation or translational repression. The aim of the present study was to investigate the expression and func...

journal_title：Oncology letters

authors： Kan Q,Su Y,Yang H

更新日期：2017-12-01 00:00:00

abstract：:The Ganoderma lucidum (G. lucidum) mushroom is one of the most extensively studied functional foods, known for its numerous health benefits, including the inhibition of tumor cell growth. The present study assessed the anti-proliferative and pro-apoptotic activity of a novel G. lucidum polysaccharide peptide (GL-PP) i...

journal_title：Oncology letters

authors： Wang C,Lin D,Chen Q,Lin S,Shi S,Chen C

更新日期：2018-04-01 00:00:00

abstract：:Current endocrine therapies for females with estrogen receptor-positive breast cancer have facilitated substantial improvements in outcomes. The effectiveness of endocrine therapy is limited by either initial de novo resistance or acquired endocrine resistance. Multiple mechanisms responsible for endocrine resistance ...

journal_title：Oncology letters

authors： Zhou J,Teng R,Wang Q,Xu C,Guo J,Yuan C,Shen J,Hu W,Wang L,Xie S

更新日期：2013-08-01 00:00:00

abstract：:The present study aimed to investigate the clinical characteristics, diagnosis and treatment of accessory breast cancer, and contribute valuable information regarding this rare tumour to the current literature, ultimately facilitating the development of improved treatment strategies. The present study reported the cas...

journal_title：Oncology letters

authors： Zhang S,Yu YH,Qu W,Zhang Y,Li J

更新日期：2015-09-01 00:00:00

abstract：:The current report presents the case of a 43-year-old male suffering from a penile cutaneous horn. A surgical excision of the lesion was performed and histopathology demonstrated hyperkeratosis, dyskeratosis and epithelial hyperplasia. The cutaneous horn progressed to squamous cell carcinoma <1.5 months following surg...

journal_title：Oncology letters

authors： Zhou Y,Tang Y,Tang J,Xia B,Dai Y

更新日期：2014-09-01 00:00:00

abstract：:Primary mediastinal seminoma is a rare extragonadal germ cell tumour that mainly occurs in males. The present study reports the case of a 27-year-old woman that presented with superior vena cava syndrome and a large mass in the mediastinum, which was diagnosed as primary female mediastinal seminoma. The patient receiv...

journal_title：Oncology letters

authors： Cao J,Zhou Y,Zou F,Ma JA,Hu C

更新日期：2017-03-01 00:00:00

abstract：:Lung cancer is the most common cause of cancer-related mortality in men and women. Non-small cell lung cancer (NSCLC) represents close to 90% of all lung cancers. When diagnosed, >50% of patients are >65 years old. Through an improved understanding of the molecular mechanisms involved in lung oncogenesis, molecular-ta...

journal_title：Oncology letters

authors： Antonelli G,Libra M,Panebianco V,Russo AE,Vitale FV,Colina P,D'Angelo A,Rossello R,Ferraù F

更新日期：2016-01-01 00:00:00

abstract：:The aim of the present study was to investigate whether oridonin is able to increase the effects of lentinan (LNT) in HepG2 human hepatoblastoma cells by MTT, flow cytometry, reverse transcription-quantitative polymerase chain reaction and western blot analysis. The in vitro results demonstrated that 20 µg/ml of orido...

journal_title：Oncology letters

authors： Sun Z,Han Q,Duan L,Yuan Q,Wang H

更新日期：2018-02-01 00:00:00

abstract：:Cancer is a histologically and genetically heterogeneous population of tumor cells that exhibits distinct molecular profiles determined by epigenetic alterations. P-element-induced wimpy testis (PIWI) proteins in complex with PIWI-interacting RNA (piRNA) have been previously demonstrated to be involved in epigenetic r...

journal_title：Oncology letters

authors： Litwin M,Szczepańska-Buda A,Piotrowska A,Dzięgiel P,Witkiewicz W

更新日期：2017-05-01 00:00:00

abstract：:Dopamine receptor 2 (DR2) may be a biomarker for various types of cancer. Ovarian cancer cells overexpress DR2; therefore, blocking DR2 may be a novel treatment strategy for ovarian cancer. Thioridazine, a DR2 blocker, has antineoplastic activity in a variety of cancer cells. In view of the requirement for novel thera...

journal_title：Oncology letters

authors： Yong M,Yu T,Tian S,Liu S,Xu J,Hu J,Hu L

更新日期：2017-12-01 00:00:00

abstract：:erbB-2 is amplified or overexpressed in approximately 30% of human breast cancers, and has been associated with poor prognosis and therapeutic resistance. Previous studies have suggested that erbB-2 overexpression in transgenic mice induces genomic instability; however, the patterns of genetic lesions vary with indivi...

journal_title：Oncology letters

authors： Kim YM,Ma Z,Lee S,Lee J,Li S,Yang X

更新日期：2011-11-01 00:00:00

abstract：:Breast cancer 1 (BRCA1) and insulin-like growth factor 1 receptor (IGF1R) are critical in ovarian cancer progression. However, the crosstalk between the BRCA1 and IGF1R signaling pathways in ovarian cancer remains largely unknown. The effects of BRCA1 on IGF1R were assessed in 121 serous ovarian cancer patients (BRCA1...

journal_title：Oncology letters

authors： Liu B,Li D,Guan YF

更新日期：2014-05-01 00:00:00

abstract：:Matrix metalloproteinases (MMPs) exhibit an important function in extracellular matrix degradation. MMPs modulate the activation of growth factors, cytokines and metastasis. At present, the effect of exercise on serum levels of MMP-2 and -9 remains unclear. The aim of the present study was to investigate the effect of...

journal_title：Oncology letters

authors： Giganti MG,Tresoldi I,Sorge R,Melchiorri G,Triossi T,Masuelli L,Lido P,Albonici L,Foti C,Modesti A,Bei R

更新日期：2016-09-01 00:00:00

abstract：:Platinum-compound chemotherapy is known to have ototoxic side-effects. However, there is a paucity of literature examining hearing function prospectively and longitudinally in cohorts containing paediatric and adult patients treated within the same cisplatin- or carboplatin-containing treatment trial protocols. In Ger...

journal_title：Oncology letters

authors： Nitz A,Kontopantelis E,Bielack S,Koscielniak E,Klingebiel T,Langer T,Paulides M

更新日期：2013-01-01 00:00:00

abstract：:MicroRNAs (miRs) are an emerging class of non-coding, endogenous and small RNA molecules that serve important functions in tumorigenesis and development. The present study investigated the expression, functions and molecular mechanism underlying miR-205 in hepatocellular carcinoma. miR-205 was downregulated in hepatoc...

journal_title：Oncology letters

authors： Zhao X,Zhou S,Wang D,He W,Li J,Zhang S

更新日期：2018-08-01 00:00:00

abstract：:Colorectal cancer (CRC) is the third most common cancer worldwide and its treatment remains a challenge. Effective control of cell survival and proliferation is critical in the prevention of oncogenesis and successful treatment of cancer. Long non-coding RNAs (lncRNAs) have emerged as primary regulators of carcinogene...

journal_title：Oncology letters

authors： Yang Y,Shen Z,Yan Y,Wang B,Zhang J,Shen C,Li T,Ye C,Gao Z,Peng G,Ye Y,Jiang K,Wang S

更新日期：2017-05-01 00:00:00