Abstract:
AIMS:The aim of the study was to evaluate the clinical utility and safety of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in patients with mediastinal and hilar lymphadenopathy and to explicitly describe the utility of this procedure in patient's outcome. METHODS:A retrospective review and analysis was conducted on 52 patients with mediastinal or hilar lymphadenopathy who underwent EBUS-TBNA from June 2012 to June 2016. All the patients were evaluated by computed tomography (CT) chest with contrast before EBUS examination. Enlarged mediastinal or hilar lymph node was defined as >1 cm short axis on the enhanced CT. RESULTS:Among the 52 patients studied, 57.7% were presented with mediastinal or hilar lymphadenopathy for diagnosis and 42.3% presented with suspected mediastinal malignancy. Paratracheal stations were the most common site for puncture in 33 lymph nodes (43%). The best diagnostic yield was obtained from subcarinal stations and the lowest yield from the hilar stations. Surgical biopsies confirmed lymphoma in six patients, tuberculosis (TB) in three, sarcoidosis in two and one had metastatic adenocarcinoma of unknown primary. The sensitivity, specificity, positive predictive value, and negative predictive value of EBUS-TBNA for diagnosis of mediastinal and hilar lymph node abnormalities were 78.6%, 100%, 100%, and 80%, respectively. The diagnostic yield of EBUS-TBNA in malignant and benign conditions was 79.0%. CONCLUSIONS:EBUS-TBNA is a safe and efficacious procedure which can be performed using conscious sedation with high yields. It can be used for the staging of malignancies as well as for the diagnosis of inflammatory and infectious conditions such as sarcoidosis and TB.
journal_name
Ann Thorac Medjournal_title
Annals of thoracic medicineauthors
Aljohaney AAdoi
10.4103/atm.ATM_317_17subject
Has Abstractpub_date
2018-04-01 00:00:00pages
92-100issue
2eissn
1817-1737issn
1998-3557pii
ATM-13-92journal_volume
13pub_type
杂志文章abstract::This paper summarizes the roundtable discussion in September 25, 2013, Riyadh, Saudi Arabia as part of the World Sepsis Day held in King Abdulaziz Medical City, Riyadh. The objectives of the roundtable discussion were to (1) review the chasm between the current management of sepsis and best practice, (2) discuss syste...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.134066
更新日期:2014-07-01 00:00:00
abstract:INTRODUCTION:Prolonged use of oral corticosteroids is a risk factor for osteoporosis. However, the effect of inhaled corticosteroids (ICS) on bone mineral density (BMD) of asthmatic patients remains controversial. OBJECTIVES:We aimed to determine the prevalence of osteopenia and osteoporosis in our patients with asthm...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.94522
更新日期:2012-04-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:The goal of the study was to assess asthma control using asthma control test (ACT) and to explore the factors that effects asthma control among participants with bronchial asthma in the outpatient clinic setting. METHODS:This cross-sectional descriptive study was conducted in the outpatient prima...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.152450
更新日期:2015-04-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Physicians may experience periods of acute sleep deprivation while on-call, in addition to baseline chronic sleep deprivation which may affect physicians' performance and patients' safety. The purpose of this study was to determine the effect of acute sleep deprivation due to working long on-ca...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.105715
更新日期:2013-01-01 00:00:00
abstract::We report a case of bronchial Dieulafoy's disease in the pediatric age. Angio-computed tomography scan and arteriography addressed us to diagnosis. Bronchial endoscopy with biopsy was avoided due to the high risk of developing a life-threatening hemorrhage. Transcatheter embolization of the bleeding bronchial artery w...
journal_title:Annals of thoracic medicine
pub_type:
doi:10.4103/atm.ATM_163_20
更新日期:2020-10-01 00:00:00
abstract:BACKGROUND:The IL-4 receptor alpha subunit (IL-4Rα), when associated with the common gamma chain receptor, or the IL-13Rα1 subunit, transduces signals to STAT6 in response to IL-4 and IL-13 stimulations. This results in a number of cell-specific responses including Th2 differentiation, lymphocyte proliferation and IgE ...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.128849
更新日期:2014-04-01 00:00:00
abstract::Advances in our understanding of human immunodeficiency virus (HIV) infection have led to improved care and incremental increases in survival. However, the pulmonary manifestations of HIV/acquired immunodeficiency syndrome (AIDS) remain a major cause of morbidity and mortality. Respiratory complaints are not infrequen...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.69106
更新日期:2010-10-01 00:00:00
abstract:BACKGROUND:Pulmonary rehabilitation (PR) programs proven to be one of the most effective treatment options for respiratory diseases; yet, they are not well-established in hospitals in Saudi Arabia. AIM:To determine the main barriers for setting up PR programs in Saudi Arabia. METHODS:A cross-sectional study was condu...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.180028
更新日期:2016-04-01 00:00:00
abstract:INTRODUCTION:Ventilator-associated pneumonia (VAP) is one of the most serious hospital-acquired infections to occur among mechanically ventilated patients. Many risk factors for VAP have been identified in the literature; however, there is a lack of studies examining the association between endotracheal tube (ETT) repo...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/atm.ATM_26_19
更新日期:2019-10-01 00:00:00
abstract:AIMS:We hypothesized that if we control for food composition, caloric intake, light exposure, sleep schedule, and exercise, intermittent fasting would not influence the circadian pattern of melatonin. Therefore, we designed this study to assess the effect of intermittent fasting on the circadian pattern of melatonin. ...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/atm.ATM_15_17
更新日期:2017-07-01 00:00:00
abstract::Pleural effusion is considered to be a rare manifestation of pulmonary sarcoidosis, but hemorrhagic effusion secondary to it is a very uncommon clinical presentation. This case is reported due to the rare manifestation in pulmonary sarcoidosis presenting clinically as hemorrhagic pleural effusion. ...
journal_title:Annals of thoracic medicine
pub_type:
doi:10.4103/1817-1737.44783
更新日期:2009-01-01 00:00:00
abstract:AIMS:Flexible bronchoscopy is a common procedure performed in pulmonary medicine, critical care, and thoracic surgery. In this study, we aimed to assess the prevalence and predictors of anxiety in patients undergoing diagnostic bronchoscopy. METHODS:This is a prospective study conducted at King Abdulaziz University Ho...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/atm.ATM_38_19
更新日期:2019-07-01 00:00:00
abstract::Tracheobronchial obstruction along with compression of pulmonary vessels is a rare complication after stenting of aortic aneurysm. We present this rare situation in a young patient who underwent stenting of traumatic thoracic aortic aneurysm and developed this near fatal complication and also the conservative manageme...
journal_title:Annals of thoracic medicine
pub_type:
doi:10.4103/1817-1737.74275
更新日期:2011-01-01 00:00:00
abstract::Pulmonary rehabilitation (PR) is an integral component of the comprehensive management plan of patients with chronic lung diseases by addressing their functional and psychological deficits. PR is generally recommended to symptomatic patients with chronic lung diseases who develop shortness of breath on their own pace ...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章,评审
doi:10.4103/1817-1737.124408
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:Adequate sleep has been considered important for the adolescent's health and well being. On the other hand, self-imposed sleep curtailment is now recognized as a potentially important and novel risk factor for obesity. The present study aimed to assess the prevalence of short sleep duration and its associati...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.98845
更新日期:2012-07-01 00:00:00
abstract::There is a worldwide drive for the home management of chronic respiratory diseases. With the widespread use of home intravenous (IV) treatment for cystic fibrosis (CF) pulmonary exacerbations (PExs), evidence pointing to an inferior outcome of care for home-treated patients in comparison to hospital-treated patients i...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.53346
更新日期:2009-07-01 00:00:00
abstract:INTRODUCTION:Fiber-optic bronchoscopy (FOB) with bronchoalveolar lavage (BAL) is a common procedure performed in immunocompromised patients with undiagnosed pulmonary pathology. Identifying patients with the highest potential diagnostic yield may help to avoid morbidity in patients unlikely to benefit from the procedur...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.114302
更新日期:2013-07-01 00:00:00
abstract:BACKGROUND:There is limited data about the performance of QuantiFERON-TB Gold (QFT-G) test in detecting latent tuberculosis infection (LTBI) in our region. We intended to determine the performance of QFT-G compared to conventional tuberculin skin test (TST) in detecting LTBI in HIV-positive individuals in Iran. METHOD...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.58959
更新日期:2010-01-01 00:00:00
abstract:OBJECTIVES:The effects of first-line chemotherapy on overall survival (OS) might be confounded by subsequent therapies in patients with small cell lung cancer (SCLC). We examined whether progression-free survival (PFS), post-progression survival (PPS), and tumor response could be valid surrogate endpoints for OS after ...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.146885
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:While lung cancer is the leading cancer cause of death, it is largely preventable. Furthermore, early diagnosis enhances the chance of cure. Therefore, we developed guidelines for lung cancer prevention and early detection. METHODS:A multidisciplinary team of experts in lung cancer representing different he...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/atm.ATM_147_18
更新日期:2018-10-01 00:00:00
abstract:BACKGROUND:Osteoporosis, the most common extra-pulmonary complication of chronic obstructive pulmonary disease (COPD), may be related to general causes or COPD-specific causes such as low forced expiratory volume in 1 s (FEV1) and hypoxia. A few studies reported that emphysema is an independent risk factor for osteopor...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/atm.ATM_357_16
更新日期:2017-04-01 00:00:00
abstract::[This corrects the article on p. 100 in vol. 10, PMID: 25829960.]. ...
journal_title:Annals of thoracic medicine
pub_type: 已发布勘误
doi:10.4103/1817-1737.160849
更新日期:2015-07-01 00:00:00
abstract::Pulmonary hypertension (PH) in the Intensive Care Unit (ICU) may be due to preexisting pulmonary vascular lung disease, liver disease, or cardiac diseases. PH also may be caused by critical illnesses, such as acute respiratory distress syndrome (ARDS), acute left ventricular dysfunction and pulmonary embolism, or may ...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.134056
更新日期:2014-07-01 00:00:00
abstract::With increased exposure of patients to routine imaging, incidental benign intrathoracic masses are frequently recognized. Most have classical imaging features, which are pathognomonic for their benignity. The aim of this pictorial review is to educate the reader of radiological features of several types of intrathorac...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章,评审
doi:10.4103/1817-1737.160365
更新日期:2015-10-01 00:00:00
abstract::Patient-ventilator asynchrony (PVA) is common in patients receiving noninvasive ventilation (NIV). This occurs primarily when the triggering and cycling-off of ventilatory assistance are not synchronized with the patient's inspiratory efforts and could result in increased work of breathing and niv failure. In general,...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章,评审
doi:10.4103/atm.ATM_24_19
更新日期:2020-01-01 00:00:00
abstract::NASAM (National Approach to Standardize and Improve Mechanical Ventilation) is a national collaborative quality improvement project in Saudi Arabia. It aims to improve the care of mechanically ventilated patients by implementing evidence-based practices with the goal of reducing the rate of ventilator-associated event...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/atm.ATM_63_19
更新日期:2019-04-01 00:00:00
abstract::Chronic cough in childhood is associated with a high morbidity and decreased quality of life. Protracted bacterial bronchitis (PBB) seems to be the second most common cause of chronic cough in children under 6 years of age. Its main clinical feature is represented by wet cough that worsens when changing posture and im...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章,评审
doi:10.4103/atm.ATM_12_17
更新日期:2018-01-01 00:00:00
abstract::A 12-hour-old male infant presented with prolapsed abdominal content through a defect on left side of chest wall with respiratory distress. A thorough clinical examination suggested absence of ectopia cordis, abdominal wall defect, and any bony anomaly. The child expired after 6 hours of admission because of respirato...
journal_title:Annals of thoracic medicine
pub_type:
doi:10.4103/1817-1737.41916
更新日期:2008-07-01 00:00:00
abstract::For some years now, we have been living with the fear of an impending pandemic of avian influenza (AI). Despite the recognition, in 1996, of the global threat posed by the highly pathogenic H5N1 influenza virus found in farmed geese in Guangdong Province, China, planning for the anticipated epidemic remains woefully i...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.43085
更新日期:2008-10-01 00:00:00
abstract::Chronic cough is associated with repetitive injury to the upper airway and trachea, which can lead to an underdiagnosed pathology known as "cough-induced" laryngotracheitis (CILT). In this report, we describe a case of CILT that responded well to dual therapy. ...
journal_title:Annals of thoracic medicine
pub_type:
doi:10.4103/atm.ATM_21_18
更新日期:2018-07-01 00:00:00