Transplantation of Bone Marrow Mesenchymal Stem Cells Prevents Radiation-Induced Artery Injury by Suppressing Oxidative Stress and Inflammation.

abstract：:Sarcopenia is the loss of muscle mass accompanied by a decrease in muscle strength and resistance and is the main cause of disability among the elderly. Muscle loss begins long before there is any clear physical impact in the senior adult. Despite all this, the molecular mechanisms underlying muscle aging are far from...

journal_title：Oxidative medicine and cellular longevity

authors： Del Campo A,Jaimovich E,Tevy MF

更新日期：2016-01-01 00:00:00

abstract：:Methamphetamine (MA) leads to cardiac and pulmonary toxicity expressed as increases in inflammatory responses and oxidative stress. However, some interactions may exist between oxidative stress and endoplasmic reticulum stress (ERS). The current study is designed to investigate if both oxidative stress and ERS are inv...

journal_title：Oxidative medicine and cellular longevity

authors： Wang Y,Gu YH,Liu M,Bai Y,Liang LY,Wang HL

更新日期：2017-01-01 00:00:00

abstract：:Barley grass powder is the best functional food that provides nutrition and eliminates toxins from cells in human beings; however, its functional ingredients have played an important role as health benefit. In order to better cognize the preventive and therapeutic role of barley grass for chronic diseases, we carried ...

journal_title：Oxidative medicine and cellular longevity

authors： Zeng Y,Pu X,Yang J,Du J,Yang X,Li X,Li L,Zhou Y,Yang T

更新日期：2018-04-04 00:00:00

abstract：Objective:Cholesterol oxidation products have an established proatherogenic and cytotoxic effect. An increased exposure to these substances may be associated with the development of atherosclerosis and cancers. Relatively little, though, is known about the effect of phytosterol oxidation products, although phytosterols...

journal_title：Oxidative medicine and cellular longevity

authors： Wielkoszyński T,Zalejska-Fiolka J,Strzelczyk JK,Owczarek AJ,Cholewka A,Krawczyk A,Stanek A

更新日期：2019-11-15 00:00:00

abstract：:Prostate carcinoma causes a great number of deaths every year; therefore, there is an urgent need to find new drug candidates to treat advanced prostate cancer. Isobavachalcone (IBC) is the chalcone composition of Psoralea corylifolia Linn used in traditional Chinese medicine. Although IBC demonstrates potent anticanc...

journal_title：Oxidative medicine and cellular longevity

authors： Li K,Zheng Q,Chen X,Wang Y,Wang D,Wang J

更新日期：2018-10-16 00:00:00

abstract：:We have demonstrated that neural progenitor cells (NPCs) protect endothelial cells (ECs) from oxidative stress. Since exosomes (EXs) can convey the benefit of parent cells through their carried microRNAs (miRs) and miR-210 is ubiquitously expressed with versatile functions, we investigated the role of miR-210 in the e...

journal_title：Oxidative medicine and cellular longevity

authors： Liu H,Wang J,Chen Y,Chen Y,Ma X,Bihl JC,Yang Y

更新日期：2017-01-01 00:00:00

abstract：:Pequi (Caryocar brasiliense) is an endemic species from Brazilian Cerrado, and their fruits are widely used in regional cuisine. In this work, a crude hydroalcoholic extract (CHE) of C. brasiliense leaves and its resulting fractions in hexane (HF), chloroform (CF), ethyl acetate (EAF), and butanol (BF) were investigat...

journal_title：Oxidative medicine and cellular longevity

authors： de Oliveira TS,Thomaz DV,da Silva Neri HF,Cerqueira LB,Garcia LF,Gil HPV,Pontarolo R,Campos FR,Costa EA,Dos Santos FCA,de Souza Gil E,Ghedini PC

更新日期：2018-10-21 00:00:00

abstract：:Galectin-3 is an important modulator of several biological functions. It has been implicated in numerous disease conditions, particularly in the long-term complications of diabetes because of its ability to bind the advanced glycation/lipoxidation end products that accumulate in target organs and exert their toxic eff...

journal_title：Oxidative medicine and cellular longevity

authors： Menini S,Iacobini C,Blasetti Fantauzzi C,Pesce CM,Pugliese G

更新日期：2016-01-01 00:00:00

abstract：Background:Mitochondrial dynamics (mtDYN) has been proposed as a bridge between mitochondrial dysfunction and insulin resistance (IR), which is involved in the pathogenesis of type 2 diabetes (T2D). Our previous study has identified that mitochondrial DNA (mtDNA) haplogroup B4 is a T2D-susceptible genotype. Using trans...

journal_title：Oxidative medicine and cellular longevity

authors： Lin HY,Weng SW,Chang YH,Su YJ,Chang CM,Tsai CJ,Shen FC,Chuang JH,Lin TK,Liou CW,Lin CY,Wang PW

更新日期：2018-09-30 00:00:00

abstract：:Purpose. To investigate the preventive effect of resveratrol (RES) on the formation of portal vein system thrombosis (PVST) in a rat fibrosis model. Methods. A total of 64 male SD rats, weighing 200-300 g, were divided into five groups: Sham operation, Splenectomy I, Splenectomy II, RES, and low molecular weight hepar...

journal_title：Oxidative medicine and cellular longevity

authors： Xu M,Xue W,Ma Z,Bai J,Wu S

更新日期：2016-01-01 00:00:00

abstract：Objective:Chidamide has a broad spectrum of antitumor activity but its function on glioma remains unknown. The increase of reactive oxygen species (ROS) and reactive nitrogen species (RNS) may control glioma risk by promoting its apoptosis and necrosis. Hedgehog pathway is crucial to glioma cell proliferation and contr...

journal_title：Oxidative medicine and cellular longevity

authors： Zhou H,Han L,Wang H,Wei J,Guo Z,Li Z

更新日期：2020-03-11 00:00:00

abstract：:Aging is associated with neuronal loss, gross weight reduction of the brain, and glial proliferation in the cortex, all of which lead to functional changes in the brain. It is known that oxidative stress is a critical factor in the pathogenesis of aging; additionally, growing evidence suggests that excessive nitric ox...

journal_title：Oxidative medicine and cellular longevity

authors： Jung J,Na C,Huh Y

更新日期：2012-01-01 00:00:00

abstract：:Hypoxia, as one of the severe cellular stresses, can cause cellular injury and even cell death. Apoptosis is the main mechanism of regulating cell death and is closely related to the cell death caused by hypoxia. However, hypoxia-induced apoptosis is not entirely the result of direct hypoxic stimulus of cells. In rece...

journal_title：Oxidative medicine and cellular longevity

authors： Guo Y,Tan J,Miao Y,Sun Z,Zhang Q

更新日期：2019-04-17 00:00:00

abstract：:Although moderate physical exercise is considered an essential component of a healthy lifestyle that leads the organism to adapt itself to different stresses, exercise, especially when exhaustive, is also known to induce oxidative stress, inflammation, and muscle damage. Many efforts have been carried out to identify ...

journal_title：Oxidative medicine and cellular longevity

authors： Malaguti M,Angeloni C,Hrelia S

更新日期：2013-01-01 00:00:00

abstract：:Three cosmetically important skin lightening agents, hydroquinone (HQ), kojic acid (KA), and niacinamide (NA), consume the bulk of successful skin lightening ingredients in cosmetic applications. However, the mechanisms by which these ingredients work are still unclear. In this study, melanocytes and keratinocytes wer...

journal_title：Oxidative medicine and cellular longevity

authors： Gruber JV,Holtz R

更新日期：2013-01-01 00:00:00

abstract：:The prodrug potential of Mahonia aquifolium, a plant used for centuries in traditional medicine, recently gained visibility in the literature, and the activity of several active compounds isolated from its extracts was studied on biologic systems in vitro and in vivo. Whereas the antioxidative and antitumor activities...

journal_title：Oxidative medicine and cellular longevity

authors： Andreicuț AD,Fischer-Fodor E,Pârvu AE,Ţigu AB,Cenariu M,Pârvu M,Cătoi FA,Irimie A

更新日期：2019-12-14 00:00:00

abstract：:This work reviews concepts regarding oxidative stress and the mechanisms by which endogenous and exogenous factors produce reactive oxygen species (ROS). It also surveys the relationships between oxidative stress, circadian rhythms, and retinal damage in humans, particularly those related to light and photodamage. In ...

journal_title：Oxidative medicine and cellular longevity

authors： Fanjul-Moles ML,López-Riquelme GO

更新日期：2016-01-01 00:00:00

abstract：:Calenduloside E (CE) is a natural triterpenoid saponin isolated from Aralia elata (Miq.) Seem., a well-known traditional Chinese medicine. Our previous studies have shown that CE exerts cardiovascular protective effects both in vivo and in vitro. However, its role in myocardial ischemia/reperfusion injury (MIRI) and t...

journal_title：Oxidative medicine and cellular longevity

authors： Wang M,Wang RY,Zhou JH,Xie XH,Sun GB,Sun XB

更新日期：2020-08-31 00:00:00

abstract：:Oleuropein (OP) is a bioactive compound derived from plants of the genus Oleaceae exhibiting antitumor properties in several human cancers, including non-small-cell lung cancer (NSCLC). Recent evidence suggests that OP has proapoptotic effects on NSCLC cells via the mitochondrial apoptotic pathway. However, the exact ...

journal_title：Oxidative medicine and cellular longevity

authors： Antognelli C,Frosini R,Santolla MF,Peirce MJ,Talesa VN

更新日期：2019-07-22 00:00:00

abstract：:The cystine/glutamate exchanger (system xc (-)) mediates the transport of cystine into the cell in exchange for glutamate. By releasing glutamate, system xc (-) can potentially cause excitotoxicity. However, through providing cystine to the cell, it regulates the levels of cellular glutathione (GSH), the main endogeno...

journal_title：Oxidative medicine and cellular longevity

authors： Albano R,Raddatz NJ,Hjelmhaug J,Baker DA,Lobner D

更新日期：2015-01-01 00:00:00

abstract：:Patients with triple negative breast cancer (TNBC) often suffer relapse, and clinical improvements offered by radiotherapy and chemotherapy are modest. Although targeted therapy and immunotherapy have been a topic of significant research in recent years, scientific developments have not yet translated to significant i...

journal_title：Oxidative medicine and cellular longevity

authors： He Z,Zhang H,Li H,Wang Y,Qian J,Cai X,Sun L,Huang J

更新日期：2020-11-05 00:00:00

abstract：:The ability to produce cold plasma at atmospheric pressure conditions was the basis for the rapid growth of plasma-related application areas in biomedicine. Plasma comprises a multitude of active components such as charged particles, electric current, UV radiation, and reactive gas species which can act synergisticall...

journal_title：Oxidative medicine and cellular longevity

authors： Bernhardt T,Semmler ML,Schäfer M,Bekeschus S,Emmert S,Boeckmann L

更新日期：2019-09-03 00:00:00

abstract：:Mitochondrial DNA (mtDNA) damage is associated with the development of cardiovascular diseases. Cardiac aging plays a central role in cardiovascular diseases. There is accumulating evidence linking cardiac aging to mtDNA damage, including mtDNA mutation and decreased mtDNA copy number. Current wisdom indicates that mt...

journal_title：Oxidative medicine and cellular longevity

authors： Quan Y,Xin Y,Tian G,Zhou J,Liu X

更新日期：2020-03-26 00:00:00

abstract：:Eugenia dysenterica ex DC Mart. (Myrtaceae), popularly known as "cagaita," is a Brazilian plant rich in polyphenols and other antioxidant compounds. Aiming to evaluate the potential use of cagaita in pathologies involving oxidative stress, such as neurodegenerative disorders, this study investigated its antioxidant po...

journal_title：Oxidative medicine and cellular longevity

authors： Thomaz DV,Peixoto LF,de Oliveira TS,Fajemiroye JO,da Silva Neri HF,Xavier CH,Costa EA,Dos Santos FCA,de Souza Gil E,Ghedini PC

更新日期：2018-09-19 00:00:00

abstract：:We recently showed that combination therapy with losartan and pioglitazone provided synergistic effects compared with monotherapy in improving lesions of renal structure and function in Sprague-Dawley rats fed with a high-fat, high-sodium diet and 20% sucrose solution. This study was designed to explore the underlying...

journal_title：Oxidative medicine and cellular longevity

authors： Kong X,Zhang Y,Wu HB,Li FX,Zhang DY,Su Q

更新日期：2012-01-01 00:00:00

abstract：:Stem cells derived from elderly donors or harvested by repeated subculture exhibit a marked decrease in proliferative capacity and multipotency, which not only compromises their therapeutic potential but also raises safety concerns for regenerative medicine. NANOG-a well-known core transcription factor-plays an import...

journal_title：Oxidative medicine and cellular longevity

authors： Liu F,Shi J,Zhang Y,Lian A,Han X,Zuo K,Liu M,Zheng T,Zou F,Liu X,Jin M,Mu Y,Li G,Su G,Liu J

更新日期：2019-12-04 00:00:00

abstract：:Ischemia-reperfusion is a common cause for acute kidney injury and can lead to distant organ dysfunction. Glutathione is a major endogenous antioxidant and its depletion directly correlates to ischemia-reperfusion injury. The liver has high capacity for producing glutathione and is a key organ in modulating local and ...

journal_title：Oxidative medicine and cellular longevity

authors： Shang Y,Siow YL,Isaak CK,O K

更新日期：2016-01-01 00:00:00

abstract：:Hemolytic diseases are characterized by an accelerated breakdown of red blood cells (RBCs) and the release of hemoglobin (Hb). Following, RBC lysis Hb oxidation occurs with the formation of different redox states of Hb (metHb and ferrylHb) and the release of heme. ferrylHb is unstable and decomposes to metHb with the ...

journal_title：Oxidative medicine and cellular longevity

authors： Nyakundi BB,Erdei J,Tóth A,Balogh E,Nagy A,Nagy B Jr,Novák L,Bognár L,Paragh G,Kappelmayer J,Jeney V

更新日期：2020-04-25 00:00:00

abstract：:Parkinson's disease is a neurodegenerative disorder characterized by movement alterations caused by reduced dopaminergic neurotransmission in the nigrostriatal pathway, presumably by oxidative stress (OS). MPP(+) intrastriatal injection leads to the overproduction of free radicals (FR). The increasing formation of FR ...

journal_title：Oxidative medicine and cellular longevity

authors： Rubio-Osornio M,Gorostieta-Salas E,Montes S,Pérez-Severiano F,Rubio C,Gómez C,Ríos C,Guevara J

更新日期：2015-01-01 00:00:00

abstract：:The present study discusses about the effects of a combination of probiotics able to stimulate the immune system of patients affected by Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME). To this purpose, patients diagnosed according to Fukuda's criteria and treated with probiotics were analyzed by means of ...

journal_title：Oxidative medicine and cellular longevity

authors： Venturini L,Bacchi S,Capelli E,Lorusso L,Ricevuti G,Cusa C

更新日期：2019-11-23 00:00:00