Mesenchymal cell differentiation and diseases: involvement of translin/TRAX complexes and associated proteins.

abstract：:The present study was designed to immunochemically identify a coronin-like protein in Babesia bovis, B. bigemina, B. divergens, and B. canis. A 2-kbp cDNA insert of B. bovis carried by plasmid BvN9 was sequenced by the dideoxichain-termination method on both strands. The cDNA insert contained a 1719-bp long open readi...

journal_title：Annals of the New York Academy of Sciences

authors： Figueroa JV,Precigout E,Carcy B,Gorenflot A

更新日期：2004-10-01 00:00:00

abstract：:In order to better understand the enhancing effects of lowered oxygen (O2) tension on the growth in vitro of granulocyte-macrophage progenitor cells (CFU-GM), the effects of oxidizing species derived from molecular O2 were assessed on CFU-GM. Low density or nonadherent low density normal human bone marrow cells were p...

journal_title：Annals of the New York Academy of Sciences

authors： Broxmeyer HE,Cooper S,Gabig T

更新日期：1989-01-01 00:00:00

abstract：:A sensitive, accurate, and simple method, called shifted termination assay (STA), was developed for detection of genetic mutations. The STA technology can be used to detect genetic mutations in polymerase chain reaction (PCR)-amplified samples of tissue, and plasma and serum that include circulating DNA containing poi...

journal_title：Annals of the New York Academy of Sciences

authors： Shackelford W,Deng S,Murayama K,Wang J

更新日期：2004-06-01 00:00:00

abstract：:Few studies have evaluated the impact of nutritional supplementation among pregnant adolescents. We examined the effects of the Rang Din Nutrition Study (RDNS) interventions on children born to mothers <20 years of age. The RDNS was a cluster-randomized effectiveness trial with four arms: (1) women and children both r...

journal_title：Annals of the New York Academy of Sciences

authors： Dewey KG,Matias SL,Mridha MK,Arnold CD

更新日期：2020-05-01 00:00:00

abstract：:1. There are several endogenous ligands that bind to I-receptors of both the I1 and I2 subclass. These include: (a) classic CDS, a partially purified entity isolated by the criteria that it displaces binding ligands to alpha 2- and I-receptors; (b) immunoreactive (ir)-CDS, a moiety that binds to antibodies raised agai...

journal_title：Annals of the New York Academy of Sciences

authors： Reis DJ,Li G,Regunathan S

更新日期：1995-07-12 00:00:00

abstract：:Vitamin E is essential for normal neurological function. It is the major lipid-soluble, chain-breaking antioxidant in the body, protecting the integrity of membranes by inhibiting lipid peroxidation. Mostly on the basis of symptoms of primary vitamin E deficiency, it has been demonstrated that vitamin E has a central ...

journal_title：Annals of the New York Academy of Sciences

authors： Sen CK,Khanna S,Roy S

更新日期：2004-12-01 00:00:00

abstract：:Prostate and breast cancer are hormone-dependent malignancies of the aging male and female and require the local production of androgens and estrogens to stimulate cell proliferation. Aldo-keto reductases (AKR) play key roles in this process. In the prostate, AKR1C3 (type 5 17beta-HSD) reduces Delta(4)-androstene-3,17...

journal_title：Annals of the New York Academy of Sciences

authors： Penning TM,Byrns MC

更新日期：2009-02-01 00:00:00

abstract：:Abnormal function of the lymphatic vessels is associated with a variety of diseases, such as tumor metastasis and lymphedema. The development of strategies for local and controlled induction or inhibition of lymphangiogenesis would thus be of major importance for the treatment of such diseases. Two growth factors, vas...

journal_title：Annals of the New York Academy of Sciences

authors： Saaristo A,Karkkainen MJ,Alitalo K

更新日期：2002-12-01 00:00:00

abstract：:In response to infection or effective vaccination, naive antigen-specific CD8+ T cells undergo a dramatic highly orchestrated activation process. Initial encounter with an appropriately activated antigen-presenting cell leads to blastogenesis and an exponential increase in antigen-specific CD8+ T cell numbers. Simulta...

journal_title：Annals of the New York Academy of Sciences

authors： Obar JJ,Lefrançois L

更新日期：2010-01-01 00:00:00

abstract：:Post-polio syndrome (PPS) describes the clinical onset of progressive muscular weakness many years after survival of acute paralytic poliomyelitis, often in muscle groups clinically unaffected by the original disease process. Prior pathologic descriptions of this often disabling, but not usually fatal, syndrome have b...

journal_title：Annals of the New York Academy of Sciences

authors： Miller DC

更新日期：1995-05-25 00:00:00

abstract：:Externally guided sensory-motor processes deteriorate with increasing age. Internally guided, for example, predictive, behavior usually helps to overcome sensory-motor delays. We studied whether predictive components of visuomotor transformation decline with age. We investigated smooth pursuit eye movements (SPEM) of ...

journal_title：Annals of the New York Academy of Sciences

authors： Sprenger A,Trillenberg P,Pohlmann J,Herold K,Lencer R,Helmchen C

更新日期：2011-09-01 00:00:00

abstract：:Most of the plasma suppressive activity was associated with alpha 2M in both normal subjects and cancer patients. alpha 2M binding to physiological levels of proteases was associated with an increase in the ability to suppress lymphocyte reactivity in the TEEM test. alpha 2M binding to proteases released a peptide tha...

journal_title：Annals of the New York Academy of Sciences

authors： Alomran A,Shenton BK,Donnelly PK,Francis DM,Proud G,Taylor RM

更新日期：1983-01-01 00:00:00

abstract：:Members of the steroid receptor superfamily, like other transcription factors, can function as transcriptional inducers as well as repressors of transcription. The mechanisms by which repression is achieved seem to be specific for the factors and [table: see text] regulatory sequences involved. Many and perhaps all of...

journal_title：Annals of the New York Academy of Sciences

authors： Renkawitz R

更新日期：1993-06-11 00:00:00

abstract：:Jackson's Personality Research Form E (PRF) was administered to a large, heterogeneous group of adult inpatients with diagnoses of alcohol and/or drug dependence. Cluster analysis of PRF factor scores yielded five distinct patient subtypes: hostile-dependent, cooperative-nonreflective, socially uninvolved, impulsive-u...

journal_title：Annals of the New York Academy of Sciences

authors： Allen JP,Fertig JB,Mattson ME

更新日期：1994-02-28 00:00:00

abstract：:Calcium-dependent activator protein for secretion (CAPS) was initially identified in brain cytosol based on its ability to reconstitute calcium-triggered dense-core vesicle (DCV) exocytosis in permeable cell lines (PC12) of adrenal chromaffin origin. Current evidence indicates that CAPS functions selectively in DCV ex...

journal_title：Annals of the New York Academy of Sciences

authors： Wassenberg JJ,Martin TF

更新日期：2002-10-01 00:00:00

abstract：:Parachlamydiaceae are potential emerging pathogens that naturally infect free-living amoebae. We investigated the affects of incubation temperature on the growth and cytopathic effect of P. acanthamoeba in Acanthamoeba polyphaga. A. polyphaga were infected with P. acanthamoeba and incubated at different temperatures f...

journal_title：Annals of the New York Academy of Sciences

authors： Greub G,La Scola B,Raoult D

更新日期：2003-06-01 00:00:00

abstract：:The Mediterranean diet is now recognized as being both limited in toxicity and abundant in nutrient and non-nutrient protective factors. A large body of basic, clinical and epidemiological studies have been developed in recent years to provide evidence of the benefits of the Mediterranean diet or its components on hea...

journal_title：Annals of the New York Academy of Sciences

authors： Covas MI,Marrugat J,Fitó M,Elosua R,de la Torre-Boronat C

更新日期：2002-05-01 00:00:00

abstract：:Methamphetamine (METH) produces nigrostriatal dopamine (DA) loss, partly resembling that which occurs in Parkinson's disease (PD). In PD there is also a marked alteration in the gut. Given the similarities between the central DA denervation produced by METH and PD, in the present study we evaluated the alterations in ...

journal_title：Annals of the New York Academy of Sciences

authors： Natale G,Kastsiuchenka O,Pasquali L,Ruggieri S,Paparelli A,Fornai F

更新日期：2008-10-01 00:00:00

abstract：:Results of therapeutic trials of transfer factor in a number of laboratories suggest clinical benefit and enhancement of immunological reactivity in patients with primary or secondary immunodeficiency diseases. Long term follow-up of 32 patients with the Wiskott-Aldrich syndrome suggested that transfer factor caused c...

journal_title：Annals of the New York Academy of Sciences

authors： Spitler LE

更新日期：1979-01-01 00:00:00

abstract：:Without landmarks, navigation is based on information about self-velocity, which is transformed to position or orientation by a process called path integration. Simple path integration tasks, such as reaching a previously seen goal by blindfolded locomotion, were often considered to be automatic and not influenced by ...

journal_title：Annals of the New York Academy of Sciences

authors： Glasauer S,Stein A,Günther AL,Flanagin VL,Jahn K,Brandt T

更新日期：2009-05-01 00:00:00

abstract：:Dopamine-beta-hydroxylase (DbetaH) deficiency is a rare autosomal dominant disorder. Due to the absence of DbetaH, there is a blocked conversion of dopamine into norepinephrine. The biochemical hallmark of this syndrome consists of a complete absence of plasma norepinephrine and epinephrine levels in conjunction with ...

journal_title：Annals of the New York Academy of Sciences

authors： Timmers HJ,Deinum J,Wevers RA,Lenders JW

更新日期：2004-06-01 00:00:00

abstract：:Circadian and other rhythmic changes in biological susceptibility and response of organisms to a large variety of physical as well as chemical agents including medications and foods are rather common phenomena. Modern chronopharmacology investigates drug effects (a) as a function of biological timing and (b) upon para...

journal_title：Annals of the New York Academy of Sciences

authors： Reinberg AE

更新日期：1991-01-01 00:00:00

abstract：:The glucocorticoid receptor (GR) is crucial for the effects of glucocorticoids (GCs). Several polymorphisms of the GR are associated with altered sensitivity to GCs. For the ER22/23EK polymorphism, a relative GC resistance has been demonstrated. In vivo, this was suggested by a smaller response to a dexamethasone supp...

journal_title：Annals of the New York Academy of Sciences

authors： Manenschijn L,van den Akker EL,Lamberts SW,van Rossum EF

更新日期：2009-10-01 00:00:00

abstract：:The authors present a multifactorial model for the development of acquired immunodeficiency syndrome (AIDS) in homosexual men. It is posited that there is no specific AIDS agent; rather, AIDS is conceptualized as the result of an interaction of the known or likely effects of repeated exposures to specific environment...

journal_title：Annals of the New York Academy of Sciences

authors： Sonnabend JA,Witkin SS,Purtilo DT

更新日期：1984-01-01 00:00:00

abstract：:We have previously shown that bone marrow will seed and proliferate in normal recipients. Transfusion of 50 million cells on each of 4 or 5 consecutive days, a total of 200-250 million cells, resulted in the recipient's marrow being 20-40% of donor origin. The present paper reported on the marked enhancement of prolif...

journal_title：Annals of the New York Academy of Sciences

authors： Brecher G,Mulcahy K,Tjio JH,Raveché E

更新日期：1985-01-01 00:00:00

abstract：:Recent discoveries have demonstrated the extraordinary plasticity of tissue-derived stem cells, raising fundamental questions about cell lineage relationships and suggesting the potential for novel cell-based therapies. We have examined this phenomenon in a potential reciprocal relationship between stem cells derived ...

journal_title：Annals of the New York Academy of Sciences

authors： Goodell MA,Jackson KA,Majka SM,Mi T,Wang H,Pocius J,Hartley CJ,Majesky MW,Entman ML,Michael LH,Hirschi KK

更新日期：2001-06-01 00:00:00

abstract：:This study aimed to assess the value of different DXA and BIA models for predicting muscle volume in mid-thigh segments obtained by MRI. Three DXA models were used: in model A, muscle was taken to be equivalent to fat-free soft tissue; in model B the thigh segment was divided into its constituent tissues using fixed a...

journal_title：Annals of the New York Academy of Sciences

authors： Elia M,Fuller NJ,Hardingham CR,Graves M,Screaton N,Dixon AK,Ward LC

更新日期：2000-05-01 00:00:00

abstract：:Both orbital and attitude dynamics employ the method of variation of parameters. In a non-perturbed setting, the coordinates (or the Euler angles) are expressed as functions of the time and six adjustable constants called elements. Under disturbance, each such expression becomes ansatz, the "constants" being endowed w...

journal_title：Annals of the New York Academy of Sciences

authors： Efroimsky M

更新日期：2005-12-01 00:00:00

abstract：:The general aim of this experiment was to investigate the processes involved in reading musical notation and to study the relationship between written music and its auditory representation. Our main interest was to determine if musicians can develop expectancies for plausible or implausible auditory events on the sole...

journal_title：Annals of the New York Academy of Sciences

authors： Schön D,Besson M

更新日期：2003-11-01 00:00:00

abstract：:Neuropathology is one approach to the effort to elucidate the pathophysiology of suicide. Initial neurochemical studies focusing on the roles of serotonin (5-HT) and noradrenaline (NE) abnormalities in brains of suicide victims have been somewhat inconsistent. More recently developed methodologies, including quantitat...

journal_title：Annals of the New York Academy of Sciences

authors： Bachus SE,Hyde TM,Akil M,Weickert CS,Vawter MP,Kleinman JE

更新日期：1997-12-29 00:00:00