Abstract：
:Over the past decades, a number of novel compounds, which are produced in the marine environment, have been found to exhibit the anticancer effects. This review focuses on molecular targets of marine-derived anticancer candidates in clinical and preclinical studies. They are kinases, transcription factors, histone deacetylase, the ubiquitin-proteasome system, and so on. Specific emphasis of this review paper is to provide information on the optimization of new target compounds for future research and development of anticancer drugs, based on the identification of structures of these target molecules and parallel compounds.
journal_name
Mar Drugsjournal_title
Marine drugsauthors
Song X,Xiong Y,Qi X,Tang W,Dai J,Gu Q,Li Jdoi
10.3390/md16050175subject
Has Abstractpub_date
2018-05-22 00:00:00issue
5issn
1660-3397pii
md16050175journal_volume
16pub_type
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