Abstract：
Objective:Zinc is a vital trace element and its deficiency in cirrhosis might potentiate the development of hepatic encephalopathy. The objective of this study was to assess the zinc levels in serum of patients having viral cirrhosis and compare it with normal healthy controls. Methods:This study was conducted in Department of Gastroenterology, Liaquat National hospital and medical college, Karachi, Pakistan; from January 2014 to December 2014. Total of 45 patients with the mean age of 52.44±8.7 years were included. The three groups of patients were made including Child Pugh Class Score B (Group-1), Child Pugh Class C (Group-2) and healthy controls (Group-3) having 15 patients in each group. Zinc levels in serum were evaluated by the help of atomic absorption spectrometry (Normal range50-150 µg/dl). Results:Total of 45 subjects was enrolled in this study. Overall prevalence of zinc deficiency was noted in 13(28.9%) patients. Mean value of zinc levels in group 1,2 and 3 were 68.09±20.85, 50.69±15.86 and 92.91±17.18µg/dL respectively. Highly statistical difference was observed in the mean zinc level between three groups p=0.0001. An inverse correlation was observed between Child Pugh Score and the zinc level in serum r=-0.498. Conclusion:Patients suffering from advanced cirrhosis appeared to have lower serum zinc levels. In patients suffering from viral cirrhosis having hepatic encephalopathy, zinc supplementation might improve clinical outcome.
journal_name
Pak J Med Scijournal_title
Pakistan journal of medical sciencesauthors
Kamani L,Shaikh Hdoi
10.12669/pjms.342.14457subject
Has Abstractpub_date
2018-03-01 00:00:00pages
478-481issue
2eissn
1682-024Xissn
1681-715Xpii
PJMS-34-478journal_volume
34pub_type
杂志文章abstract：Objective:To determine the trend of anaemia prevalence among female medical students (FMS) through self-grading along haematological parameters and its association with their nutritional indicators. Methods:This cross-sectional study was conducted at a public sector health university of Karachi among FMS from April to...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.36.7.2793
更新日期：2020-11-01 00:00:00
abstract：Objective:To evaluate the effectiveness and safety profile of combined phacoemulsification with 23G pars plana vitrectomy when compared to pars plana vitrectomy alone in phakic patients. Methods:This study was performed at Al-Ehsan Eye Hospital (tertiary care eye hospital in Lahore, Pakistan) from January 2016 to Augu...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.335.13430
更新日期：2017-09-01 00:00:00
abstract：OBJECTIVE:To identify the frequency and reasons of operations cancellation in 25 Makkah region hospitals in Saudi Arabia. METHODS:Retrospective evaluation of the rate of surgery cancellation in 25 hospitals of Makkah region was performed in this study. The data of scheduled surgeries from 15 different surgical special...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.315.7932
更新日期：2015-09-01 00:00:00
abstract：Objective:To study the clinical, biochemical and radiological features and management outcomes of patients with primary hyperparathyroidism. Methods:This retrospective study was conducted at the Aga Khan University Hospital, Karachi, Pakistan and comprised data of patients with primary hyperparathyroidism from 2008 to...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.36.6.2572
更新日期：2020-09-01 00:00:00
abstract：OBJECTIVE:To find out the frequency of vitamin D deficiency and its relation with glucose parameters and the incidence of gestational diabetes (GDM). METHODOLOGY:Gestational diabetes was diagnosed with 75 gram oral glucose tolerance test. Forty-four pregnant women diagnosed with GDM and 78 non-GDM pregnant women were ...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.291.2896
更新日期：2013-01-01 00:00:00
abstract：OBJECTIVES:To evaluate the effect of low dose Albumin i.e. 4 grams per litre of ascitic fluid after large volume paracentesis (LVP) for the prevention of paracentesis induced circulatory dysfunction (PICD) related renal impairment in cirrhosis. METHODS:Case records of all patients with cirrhosis who underwent LVP from...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.313.7281
更新日期：2015-01-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to evaluate the detection rate accuracy of Double-balloon Enteroscopy (DBE) after Capsule Endoscopy (CE) in patients with suspected small bowel diseases. METHODOLOGY:From January 2009 to March 2012, sixty-two patients with obscure small bowel diseases who underwent CE followed by DB...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.292.2927
更新日期：2013-04-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:Helicobacter pylori (H. pylori) infection is cause of several gastrointestinal diseases in humans. Virulence genes of H. pylori are associated with severity of disease and vary geographically. The aim of present study was to detect H. pylori in formalin-fixed paraffin-embedded (FFPE) tissues a...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.332.12024
更新日期：2017-03-01 00:00:00
abstract：:Doing a PhD (doctor of philosophy) for the sake of contribution to knowledge should give the student an immense enthusiasm through the PhD period. It is the time in one's life that one spends to "hit the nail on the head" in a specific area and topic of interest. A PhD consists mostly of hard work and tenacity; howeve...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.306.6378
更新日期：2014-11-01 00:00:00
abstract：Background and Objectives:Learning is an interplay between cognition and environmental factors. Any learning environment, that fulfills the intrinsic and extrinsic needs of the students will probably lead to better and more promising learning outcomes. This study aimed to investigate the student perceptions of Learning...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.35.3.712
更新日期：2019-01-01 00:00:00
abstract：OBJECTIVE:Purpose of this study was to validate that Subtenon (SB) Triamcinolone (TA) injection is an alternative to Intravitreal (IV) Triamcinolone (TA) injection for the treatment of diabetic macular edema (DME). METHODS:Forty eyes were selected having DME due to type 1 or type 2 diabetes. All the patients were trea...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.304.4810
更新日期：2014-07-01 00:00:00
abstract：OBJECTIVE:To determine the association between serum 25 hydroxyvitamin D levels and percent breast density among asymptomatic premenopausal women. METHODS:Hundred asymptomatic, pre-menopausal women who visited the General Surgery Breast Clinic, Patel Hospital, Karachi, Pakistan between 3rd March and 10th November, 201...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.325.10731
更新日期：2016-09-01 00:00:00
abstract：Objective:To explore the value of gastrointestinal endoscopy in the early diagnosis and treatment of gastrointestinal tumors and lay a foundation for the diagnosis and treatment of gastrointestinal tumors. Methods:One hundred and eight patients with gastrointestinal tumors who were admitted to our hospital from August...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.36.2.707
更新日期：2020-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Genetic studies on gestational diabetes (GDM) are relatively scarce; moreover, limited data is available for KCNQ1 polymorphism in Pakistani pregnant women. We aimed to determine the frequency of KCNQ1 rs2237895 in GDM and normal pregnant controls and its association with GDM-related phenotypes...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.326.11052
更新日期：2016-11-01 00:00:00
abstract：Background and Objective:Increased neutrophil lymphocyte ratio (NLR) is a marker as well as predictor of various cardiac and non cardiac disorders. Our aim was to assess the relationship between NLR and different level of glycemic control in type 2 diabetic patients. Methods:An observational study was conducted at dia...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.336.12900
更新日期：2017-11-01 00:00:00
abstract：OBJECTIVE:To assess the Knowledge, Attitude and Practices (KAP) towards diabetes and diabetic retinopathy in the general population of Bin Qasim Town (BQ), Karachi. METHODS:An observational, cross-sectional study was approved by Research Ethical Committee of Al-Ibrahim Eye Hospital. It included every third household b...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.311.6317
更新日期：2015-01-01 00:00:00
abstract：Objective:Medical Education Journal Club is an evidence-based approach to teach and learn critical appraisal techniques on available literature. This study evaluates the implementation and experience of two academic years of Journal club at Medical Education Department, King Saud University. Methods:We started JC in 2...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.335.13221
更新日期：2017-09-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Breakpoint cluster region-Abelson (BCR-ABL) rearrangement or Philadelphia (Ph) chromosome in Chronic Myeloid Leukemia (CML) is derived from a reciprocal chromosomal translocation between ABL gene on chromosome 9 and BCR gene on chromosome 22. This chimeric protein has various sizes and therefor...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：
更新日期：2014-07-01 00:00:00
abstract：OBJECTIVE:Fentanyl is frequently used during anesthesia induction. The use of fentanyl can cause cough through different mechanisms. Here, we aimed to investigate effects of pheniramine maleate (PM), an antihistaminic agent, and compare it with lidocaine on fentanyl induced cough. METHODS:This is a randomized double-b...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.323.9496
更新日期：2016-05-01 00:00:00
abstract：Objective:To study Agreement between Keratometric readings by VERION image guided System, Galilei G4 and Pentacam. Methods:The quasi experimental study was conducted at Armed Forces Institute of Ophthalmology, Rawalpindi, Pakistan from August 2016 to December 2016. Twenty five patients fulfilling the inclusion criteri...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.343.14577
更新日期：2018-05-01 00:00:00
abstract：Objective:To evaluate the feasibility and safety of marking targeting biopsy (MTB) in the intraoperative localization value of colon polypectomy. Methods:The clinical data from patients with polyp of colon discovered under colonoscopy from January 2014 to January 2016 were retrospectively analyzed. A total of 87 patie...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.36.2.756
更新日期：2020-01-01 00:00:00
abstract：Objectives:To assess the immediate effect of TEAM® on trauma related knowledge of undergraduate medical students and to highlight the stakeholders' acceptability of TEAM® for trauma training of undergraduate medical students. Methods:Effectiveness of TEAM® course in terms of knowledge gain was assessed using 20-item-M...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.36.6.2588
更新日期：2020-09-01 00:00:00
abstract：Objectives:Epilepsy is one of the most common chronic neurologic disorders in childhood and it affects 0.5-1% of children. The purpose of the study was to determine the prevalence and types of structural abnormalities in the epileptic children. Methods:The study was performed in Near East University and Dr. Suat Gunse...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.342.14807
更新日期：2018-03-01 00:00:00
abstract：:Objective : Oral squamous cell carcinoma (OSCC) is considered to be a serious life threatening issue for almost two decades. The objective of this study was to evaluate the over production of lipid peroxidation (LPO) byproducts and disturbances in antioxidant defense system in the pathogenesis of oral cancer. Methods ...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.303.4985
更新日期：2014-05-01 00:00:00
abstract：Objective:To compare the effects of simple saline dressings versus topical vancomycin dressings on Methicillin-resistant Staphylococcus Aureus positive chronic diabetic foot ulcers. Methods:It was quasi experimental study conducted in Combined Military Hospital Kohat and PNS-Shifa Hospital Karachi from 01 January 2017...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.35.4.368
更新日期：2019-07-01 00:00:00
abstract：OBJECTIVE:To evaluate the prevalence and the individual components of metabolic syndrome (MetS) in Jordanian adults. METHODS:In this cross sectional study, 630 adult subjects (308 men and 322 women) aged between 20-70 years were recruited from the clinics at the King Hussein Medical Center. The diagnosis of MetS was m...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.316.7714
更新日期：2015-11-01 00:00:00
abstract：OBJECTIVE:To study the efficacy, desirable and undesirable effects of locally injectable preparation of botulinum toxin in patients suffering from Benign Essential Blepharospasm (BEB). METHODS:It was a prospective study carried out from October 2006 till November 2012 at a private set up, "Dr Shakaib's Eye Clinic", in...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.296.3853
更新日期：2013-11-01 00:00:00
abstract：OBJECTIVES:To find out the clinical characteristics and risk factors for deep venous thrombosis (DVT) after gynecological surgery. METHODS:Four hundred and ninety-eight patients treated surgically in the department of gynecology of our hospital from July 2012 to May 2014 were reviewed retrospectively. The data includi...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.312.6608
更新日期：2015-03-01 00:00:00
abstract：Objectives:To assess maternal and fetal morbidity associated with placenta previa and morbidly adherent placenta (MAP). Methods:All patients with placenta previa who delivered in services hospital from April 1, 2017 to March 31, 2019 were included. Maternal and fetal outcomes were compared amongst patients with placen...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.36.5.1647
更新日期：2020-07-01 00:00:00
abstract：OBJECTIVE:To compare the neuro-radiologic findings in Systemic lupus erythematosus (SLE) patients with and without antiphospholipid antibodies (aPL) in different neuro-psychiatric manifestations. METHODS:This cross-sectional comparative study was carried out at King Khalid University Hospital, a tertiary care teaching...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.315.7975
更新日期：2015-09-01 00:00:00
