Abstract:
Objective:To study the clinical, biochemical and radiological features and management outcomes of patients with primary hyperparathyroidism. Methods:This retrospective study was conducted at the Aga Khan University Hospital, Karachi, Pakistan and comprised data of patients with primary hyperparathyroidism from 2008 to 2017. Results:Out of 103 patients, 83(80.6%) were female. Overall mean age was 59.3±16.2 years. Musculoskeletal manifestations were seen in 60(58.3%) patients and renal manifestations in 28(27.2%). Ostieits fibrosa cystica was found in 04(3.88%) patients. Overall, Ultrasound neck and sestamibi scan localized the lesion in 66 (64.1%) and 77 (76.2%) patients respectively. Among 79 patients who underwent surgery, 67 (84.8%) patients had an adenoma, 05 (6.3%) had hyperplasia and 02(2.53%) patients had parathyroid carcinoma whereas histopathology was inconclusive in 5 (6.32%) out of the 79 surgically treated patients. Disease recurrence was seen in 13 out of 79(16.45%) patients who underwent surgery. Conclusion:Primary hyperparathyroidism is associated with significant morbidity in our population. Targeted measures like improving patient awareness, routine calcium screening, vitamin D supplementation and a high index of suspicion by the clinician may help in early diagnosis of the condition and thus reduce morbidity.
journal_name
Pak J Med Scijournal_title
Pakistan journal of medical sciencesauthors
Fatima T,Das B,Sattar S,Islam Ndoi
10.12669/pjms.36.6.2572subject
Has Abstractpub_date
2020-09-01 00:00:00pages
1199-1203issue
6eissn
1682-024Xissn
1681-715Xpii
PJMS-36-1199journal_volume
36pub_type
杂志文章abstract:Objective:To compare the efficacy of oral Labetalol versus oral Nifedipine for the treatment of postpartum hypertension. Methods:A prospective randomized controlled trial with parallel assignment was conducted in the department of Obstetrics and Gynecology, Dow University of Health Sciences Karachi, Pakistan, 124 pati...
journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.35.5.812
更新日期:2019-09-01 00:00:00
abstract:OBJECTIVE:To investigate the effects of graded models on the biomechanical behavior of a bone-implant system under osteoporotic conditions. Methodology : A finite element model (FEM) of the jawbone segments with a titanium implant is used. Two types of models (a graded model and a non-graded model) are established. The...
journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.292.2963
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abstract:OBJECTIVE:To determine the disease severity in patients with Rheumatoid Arthritis (RA), at baseline and the impact of treatment on disease activity (DA) after six months of disease modifying anti-rheumatic drugs (DMARDs) therapy. METHODS:This prospective study was conducted at the 'Rheumatology Clinic' of Jinnah Postg...
journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.334.12704
更新日期:2017-07-01 00:00:00
abstract:Objective:This study was conducted to explore factors that can impact psychological health and coping strategies to help health care professionals (HCPs) to perform their duties. Methods:A cross sectional survey was conducted using structured questionnaire electronically shared with the participants after ethical appr...
journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.36.7.2988
更新日期:2020-11-01 00:00:00
abstract:Objective:During COVID-19 pandemic, the institutions in Pakistan have started online learning. This study explores the perception of teachers and students regarding its advantages, limitations and recommendations. Methods:This qualitative case study was conducted from March to April 2020. Using maximum variation sampl...
journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.36.COVID19-S4.2785
更新日期:2020-05-01 00:00:00
abstract:Objective:Medical Education Journal Club is an evidence-based approach to teach and learn critical appraisal techniques on available literature. This study evaluates the implementation and experience of two academic years of Journal club at Medical Education Department, King Saud University. Methods:We started JC in 2...
journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.335.13221
更新日期:2017-09-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to highlight cardiovascular risk factors among retired attendees attending a primary care clinic, Riyadh, Saudi Arabia. METHODS:A cross sectional study was conducted from Januaryto February 2013 at Primary Care Clinics of King Khalid University Hospital and College of Medicine, King...
journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.303.4269
更新日期:2014-05-01 00:00:00
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journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.344.14602
更新日期:2018-07-01 00:00:00
abstract:Objective:To determine the quality of life of students of a private medical college in Karachi in Pakistan. Methods:This cross sectional study was conducted among 217 medical students of Liaquat College of Medicine and Dentistry, Karachi from June 2017 to March 2018. Students were selected by a stratified sampling met...
journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.36.2.668
更新日期:2020-01-01 00:00:00
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journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.36.4.1638
更新日期:2020-05-01 00:00:00
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journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.324.10037
更新日期:2016-07-01 00:00:00
abstract::We report a case of 20 Years old girl who presented with catatonia resulting from cerebral lupus. There are few cases of catatonia being described in Systemic Lupus Erythmatoses (SLE). The patient presented to us with fever and altered sensorium. She was initially treated on lines of Acute Bacterial Meningitis/encepha...
journal_title:Pakistan journal of medical sciences
pub_type:
doi:
更新日期:2014-03-01 00:00:00
abstract:Objective:To identify the perceptions of the faculty about their current level of pedagogical skills and their desire to improve these skills in future. Methods:This cross-sectional study was conducted at two medical colleges of Dow University of Health Sciences, Karachi from March 1, 2015 to April 30, 2015. A re-vali...
journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.346.16302
更新日期:2018-11-01 00:00:00
abstract:OBJECTIVE:To identify what educational resources are used by medical students for their personal study during Primary health care (PHC) clinical rotation and the reasons for making these choices at King Saud University in Riyadh, Saudi Arabia. METHODS:A survey of 176 male and female medical students was conducted duri...
journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.322.9784
更新日期:2016-03-01 00:00:00
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journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.312.6130
更新日期:2015-03-01 00:00:00
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journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.343.14500
更新日期:2018-05-01 00:00:00
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journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.345.15262
更新日期:2018-09-01 00:00:00
abstract:OBJECTIVE:To determine faculty perception on journal club (JC) presentation at Bahria University Medical and Dental College (BUMDC), Karachi. Pakistan. METHODS:It was a cross sectional study conducted from January 2009 to December 2012 to acquire faculty member's feedback on JC presentations in structured meeting at B...
journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.311.6314
更新日期:2015-01-01 00:00:00
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journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.313.6795
更新日期:2015-01-01 00:00:00
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journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.37.1.3089
更新日期:2021-01-01 00:00:00
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journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.314.7294
更新日期:2015-07-01 00:00:00
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journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.35.3.136
更新日期:2019-01-01 00:00:00
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journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
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更新日期:2014-07-01 00:00:00
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journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.333.12397
更新日期:2017-05-01 00:00:00
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journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.342.14457
更新日期:2018-03-01 00:00:00
abstract:OBJECTIVE:To determine the various spectrum of pancytopenia with its frequency on the basis of bone marrow examination in children from 6 months to 14 years. METHODS:A retrospective descriptive study was carried out at Department of Pediatric Rehman Medical Institute Peshawar from January 2006 to December 2012. A tota...
journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.295.3865
更新日期:2013-09-01 00:00:00
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journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.333.11421
更新日期:2017-05-01 00:00:00
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journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.301.4458
更新日期:2014-01-01 00:00:00
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journal_title:Pakistan journal of medical sciences
pub_type:
doi:10.12669/pjms.291.2277
更新日期:2013-01-01 00:00:00
abstract:OBJECTIVE:To observe clinical effects of three-dimensional conformal radiotherapy combined with Tegafur Gimeracil Oteracil Potassium chemotherapy in the treatment of patients with recurrent esophagus cancer. METHODS:One hundred and twelve senile patients who suffered from esophagus cancer were selected and randomly di...
journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.325.10632
更新日期:2016-09-01 00:00:00