Abstract：
OBJECTIVE:To observe clinical effects of three-dimensional conformal radiotherapy combined with Tegafur Gimeracil Oteracil Potassium chemotherapy in the treatment of patients with recurrent esophagus cancer. METHODS:One hundred and twelve senile patients who suffered from esophagus cancer were selected and randomly divided into two groups, namely, observation group (56 cases) and control group (56 cases). The observation group adopted three-dimensional conformal radiotherapy combined with Tegafur Gimeracil Oteracil Potassium chemotherapy and the control group adopted three-dimensional conformal radiotherapy only. RESULTS:All patients completed the treatment, with good compliance. Effective rate of the observation group was 82.1%, which was significantly higher than the control group (67.9%), and the difference was statistically significant (P<0.05). Main toxic and side effects of patients of two groups were radiation esophagitis, gastrointestinal reaction, hematologic toxicities and radiative skin reaction. Differences of incidence rates of all types of toxic and side effects were not statistically significant (P>0.05). The one-year and two-year survival rates of patients of the observation group were 80.4% and 53.6%, respectively, while the control group was 55.4% and 30.4%; differences between two groups were statistically significant (P<0.05). CONCLUSION:Three-dimensional conformal radiotherapy combined with Tegafur Gimeracil Oteracil Potassium chemotherapy has definite curative effect in treating patients with recurrent esophagus cancer and can improve survival rate of patients, without increasing adverse reaction.
journal_name
Pak J Med Scijournal_title
Pakistan journal of medical sciencesauthors
Jiao Y,Shen Y,Yan H,Liu Y,Tan H,Li Jdoi
10.12669/pjms.325.10632subject
Has Abstractpub_date
2016-09-01 00:00:00pages
1141-1145issue
5eissn
1682-024Xissn
1681-715Xpii
PJMS-32-1141journal_volume
32pub_type
杂志文章abstract：OBJECTIVE:To determine the frequency and characteristics of dengue fever (DF) in patients of acute febrile illness presenting at a secondary care hospital. METHODOLOGY:The observational cross sectional study was carried out from May to October 2010 in Remedial Centre Karachi and included patients above the age of 12 y...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
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journal_title：Pakistan journal of medical sciences
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更新日期：2014-09-01 00:00:00
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更新日期：2020-11-01 00:00:00
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journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
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更新日期：2016-01-01 00:00:00
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更新日期：2019-11-01 00:00:00
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journal_title：Pakistan journal of medical sciences
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doi：
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更新日期：2017-01-01 00:00:00
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pub_type： 杂志文章
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更新日期：2013-11-01 00:00:00
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pub_type： 杂志文章
doi：10.12669/pjms.346.15942
更新日期：2018-11-01 00:00:00
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pub_type： 杂志文章
doi：10.12669/pjms.342.14656
更新日期：2018-03-01 00:00:00
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journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.335.13051
更新日期：2017-09-01 00:00:00
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更新日期：2014-11-01 00:00:00
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更新日期：2016-09-01 00:00:00
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更新日期：2016-03-01 00:00:00
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更新日期：2021-01-01 00:00:00
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doi：10.12669/pjms.306.5584
更新日期：2014-11-01 00:00:00
