Abstract：
OBJECTIVE:Purpose of this study was to validate that Subtenon (SB) Triamcinolone (TA) injection is an alternative to Intravitreal (IV) Triamcinolone (TA) injection for the treatment of diabetic macular edema (DME). METHODS:Forty eyes were selected having DME due to type 1 or type 2 diabetes. All the patients were treated with photocoagulation. IVTA was administered in one eye and SBTA in following eye of same patient. Improvement in visual acuity, macular edema and intraocular pressure was assessed before treatment and on 2(nd), 4(th), 8(th) and 12(th) week after treatment. RESULTS:After administration of IVTA, MVA was reduced from baseline value (0.805 ± 0.069Log/MAR) to (0.577 ± 0.091 Log/MAR, p<.001) at the end of treatment. Similar results were observed after SBTA administration. MVA was reduced from (0.814 ± 0.082Log/MAR) to (0.49 ± 0.080 Log/MAR, p<.001) at 12(th) week. After IVTA injection Central macular thickness was significantly reduced to (246.8 ± 25 µm, p<0.001) from (390.5 ± 17 µm). There were no significant (p=0.51) difference in both eyes receiving different routes of same treatment. After SBTA injection CMT was significantly reduced to lower values (241.5 ± 27 µm, p<0.001) from (394.4 ± 21 µm). Intraocular pressure after IVTA administration was high (2.32 ± 0.72 mm/Hg, p=0.04) as compared to baseline (1.82 ± 0.94 mm/Hg). Similar pattern was also seen after SBTA administration but to significant extent. Elevation of IoP was observed in both eyes. CONCLUSION:Subtenon Triamcinolone injection is an alternative to Intravitreal Triamcinolone Injection for Diabetic Macular Edema.
journal_name
Pak J Med Scijournal_title
Pakistan journal of medical sciencesauthors
Luo D,Zhu B,Zheng Z,Zhou H,Sun X,Xu Xdoi
10.12669/pjms.304.4810subject
Has Abstractpub_date
2014-07-01 00:00:00pages
749-54issue
4eissn
1682-024Xissn
1681-715Xjournal_volume
30pub_type
杂志文章abstract：Background and Objective:Iron deficiency anemia (IDA) has been cited as the most common cause of anemia globally. Gastrointestinal (GI) lesions are amongst the common cause of IDA. Endoscopic evaluation is the most effective way to investigate the IDA. The aim of this study was to show the association of alarming GI sy...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.344.14391
更新日期：2018-07-01 00:00:00
abstract：OBJECTIVES:Allergic rhinitis (AR) is an IgE mediated disease which is released by activation of mast cells and basophils, and often leads to sinus headache. Histamine which is the key mediator in the pathogenesis of AR, also plays an important role in the pathogenesis of migraine with nitric oxide (NO). Aim of our stud...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.292.3148
更新日期：2013-04-01 00:00:00
abstract：OBJECTIVE:This study aims to examine Gender Difference in the level of Discrimination and Stigma experienced by people diagnosed with Major Depressive Disorder in Pakistan. It was hypothesized that Women diagnosed with Depression are likely to be experiencing more Discrimination and Internalized Stigma in comparison to...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.316.8454
更新日期：2015-11-01 00:00:00
abstract：OBJECTIVE:Ventilator Associated Pneumonia (VAP) has an imperative place amongst nosocomial infections leading to increase morbidity and mortality rates. The present study aimed to determine risk factors for acquisition of ventilator- associated pneumonia in an intensive care unit (ICU). METHODS:A nested case-control s...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.295.3375
更新日期：2013-09-01 00:00:00
abstract：Objective:To determine clinical manifestations and laboratory findings in patients with BSS diagnosed through platelet aggregometry followed in a tertiary care hospital in Lahore, Pakistan. Methods:The retrospective study comprised patients who presented in Hematology and Transfusion Medicine Department of The Childre...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.35.3.980
更新日期：2019-01-01 00:00:00
abstract：Objective:To evaluate the association of miR-196a rs11614913 C/T genetic variation and its target gene annexin A1 mRNA expression with breast cancer risk in Pakistani female ethnicities. Methods:This case control study, conducted from March 2017 to November 2018 included 295 breast cancer patients, 295 controls of thr...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.35.6.1322
更新日期：2019-11-01 00:00:00
abstract：Objective:To investigate the clinical effect of ambroxol in the treatment of asthmatic bronchitis. Methods:One hundred and twenty patients with asthmatic bronchitis who were admitted to our hospital from June 2017 to August 2018 were selected as the research subjects and divided into a control group and an observation...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.36.3.1607
更新日期：2020-03-01 00:00:00
abstract：OBJECTIVES:Ventilator-associated pneumonia (VAP) is a significant cause of hospital-related infections, one that must be prevented due to its high morbidity and mortality. The purpose of this study was to evaluate the incidence and risk factors in patients developing VAP in our intensive care units (ICUs). METHODS:Thi...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.324.10381
更新日期：2016-07-01 00:00:00
abstract：OBJECTIVE:To determine the current frequency and pattern of distribution of congenital heart defects (CHD) at National Institute of Cardiovascular Diseases (NICVD), with the age at which initial diagnosis of CHD was made and the age at which the participant first visited the study center. METHODS:This is a descriptive...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.321.9029
更新日期：2016-01-01 00:00:00
abstract：Objectives:Although Spinal anesthesia is the most common and safe anesthetic method for patients undergoing cesarean section, difficult access to it is a frequent problem in operating theaters. The predictive factors for the difficulty of spinal anesthesia in patients undergoing cesarean section were investigated. Met...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.35.6.1276
更新日期：2019-11-01 00:00:00
abstract：OBJECTIVES:To determine the prevalence, predictors, triggers and educational outcome of migraine among medical students and interns in King Abdulaziz University, Jeddah, Saudi Arabia. METHODS:A cross-sectional study was completed among 566 participants selected through a multistage stratified random sample method. A v...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.332.12139
更新日期：2017-03-01 00:00:00
abstract：Objective:To correlate between hydronephrosis grades and detection of urinary stones by B-mode ultrasound imaging. Methods:This study included 210 ultrasound reports of patients who underwent abdominal ultrasound imaging in the period from 1st January 2016 to 31st October 2017, and diagnosed as hydronephrosis. Data co...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.344.14602
更新日期：2018-07-01 00:00:00
abstract：:Ralstonia mannitolilytica is a gram negative soil bacterium. Ralstonia infection though rare, has become the emerging nosocomial pathogens in hospital settings. Various clinical manifestations had been described as well as the mode of transmission. Despite its low virulence factor, it is able to survive under harsh co...
journal_title：Pakistan journal of medical sciences
pub_type：
doi：10.12669/pjms.334.13112
更新日期：2017-07-01 00:00:00
abstract：OBJECTIVE:The main objective of this study was to determine the predictors of frequent oral analgesic use among Rheumatoid Arthritis (RA) patients who were prescribed with the above medication on an 'as-needed' basis. METHODS:Patients with RA were recruited consecutively from the Rheumatology outpatient clinics in thi...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.305.5112
更新日期：2014-09-01 00:00:00
abstract：OBJECTIVE:To determine the knowledge, misconceptions and motivations towards blood donation among university students in KSA. METHODS:This cross sectional study was carried out at the King Abdulaziz University, Rabigh campus, Jeddah, KSA. A total of 326 adult males were interviewed and each individual completed a ques...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.296.4137
更新日期：2013-11-01 00:00:00
abstract：OBJECTIVE:This is aimed at investigating some coagulation and haematologic profile of HIV positive patients on highly active antiretroviral therapy in patients attending clinic at the University of Benin Teaching Hospital. METHODS:This is a correlation study comprising fifty (50) HIV positive patients on HAART between...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.316.7943
更新日期：2015-11-01 00:00:00
abstract：OBJECTIVE:To assess inpatient management of non-critically ill type 2 diabetics with different insulin regimen. METHODS:We reviewed the medical records of all non-critically ill type 2 diabetic patients more than 18 years of age in medical department of civil hospital Karachi and Dow University of Health Sciences from...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：
更新日期：2014-07-01 00:00:00
abstract：Objective:To evaluate the effects of traditional massage (TM) on spasticity and gross motor function in children with cerebral palsy (CP). Methods:This randomized control trial (RCT) was conducted with recruitment of 86 children (Dropped out= 11; Analyzed= 75) with spastic CP (diplegia) allocated randomly through seal...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.35.5.478
更新日期：2019-09-01 00:00:00
abstract：Background & Objective:Routine physiotherapy has been advocated was an effective treatment for internal shoulder impingement syndrome. However, there is lack of best exercise treatment and lots of studies are under consideration. The objective of the study was to compare the effects of Neuromobilization and routine phy...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.36.4.1545
更新日期：2020-05-01 00:00:00
abstract：Objective:To determine the efficacy of Vitamin D supplementation in achieving an early sputum conversion in vitamin D deficient smear positive pulmonary tuberculosis patients. Methods:This randomized clinical trial was done at Mayo hospital Lahore from November 2015 to August 2016. One hundred twenty patients with spu...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.344.14397
更新日期：2018-07-01 00:00:00
abstract：Objective:To find out the frequency of ZAP-70, CD38 and CD49d in patients diagnosed with CLL in our population. Methods:This is a cross sectional study conducted in Army Medical College in collaboration with Armed Forces Institute of Pathology and Military Hospital Rawalpindi from 1st January 2018 to 30th November 201...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.36.3.541
更新日期：2020-03-01 00:00:00
abstract：Objective:Zinc is a vital trace element and its deficiency in cirrhosis might potentiate the development of hepatic encephalopathy. The objective of this study was to assess the zinc levels in serum of patients having viral cirrhosis and compare it with normal healthy controls. Methods:This study was conducted in Depa...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.342.14457
更新日期：2018-03-01 00:00:00
abstract：OBJECTIVE:To study the association between Protein energy malnutrition and polio-specific immunoglobulin G antibodies production among children in Gadap Town Karachi, Pakistan. METHODS:Comparative cross sectional survey conducted at fixed EPI center and Pediatric OPD of a tertiary care hospital Karachi. Children were ...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.312.5366
更新日期：2015-03-01 00:00:00
abstract：Objectives:The aim of present study was to investigate the effect of fasting during Ramadan on plasma adiponectin and TNF-α levels. Methods:This is a cross sectional study, conducted at Federal Urdu University of Arts, Science & Technology (FUUAST), Karachi, comprising a total of 55 (50%) females and 55 (50%) males wh...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.35.1.95
更新日期：2019-01-01 00:00:00
abstract：:Objective : Oral squamous cell carcinoma (OSCC) is considered to be a serious life threatening issue for almost two decades. The objective of this study was to evaluate the over production of lipid peroxidation (LPO) byproducts and disturbances in antioxidant defense system in the pathogenesis of oral cancer. Methods ...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.303.4985
更新日期：2014-05-01 00:00:00
abstract：:A 33-year-old woman with very poor health status was admitted to our hospital because she had experienced increasing abdominal distention for three months, CT examination showed a right ovarian tumor together with massive abdominal and pelvic fluid. The patient was first treated by continuous circulatory hypothermic i...
journal_title：Pakistan journal of medical sciences
pub_type：
doi：10.12669/pjms.292.2981
更新日期：2013-04-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to explore the role of treatment for complex Atlas-Axis fractures, and compare the JOA score of surgical and conservation methods. METHODOLOGY:From June 2008 to May 2012, 33 patients suffering from Atlas-Axis fracture were included in our study. Fifteen patients received posterior c...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.293.2995
更新日期：2013-05-01 00:00:00
abstract：OBJECTIVE:We investigated the prevalence of psychiatric disorders among visitors to Faith Healers (FHs) in Riyadh, Saudi Arabia. We also studied the sociodemographic profiles for these visitors, in addition to their past psychiatric history, reason(s) for seeking FH help, and past and current treatment experience with ...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.305.5434
更新日期：2014-09-01 00:00:00
abstract：:Synergistic associations between infection and nutrition are well known. Impact of nutrition interventions on the outcomes have been scientifically assessed and reported. The role of nutrition in limiting the infection related morbidity and mortality does not appear to be a debatable question but nutrition interventio...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章,评审
doi：10.12669/pjms.36.COVID19-S4.2784
更新日期：2020-05-01 00:00:00
abstract：OBJECTIVE:To observe the fetomaternal morbidity and mortality with induction of labour in pregnant women with gestational hypertension. METHODS:The subjected study population included was 138 pregnant women with gestational hypertension. These pregnant women were between 34-40 weeks of gestational period in whom labou...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.331.10386
更新日期：2017-01-01 00:00:00
