Abstract：
OBJECTIVE:This is aimed at investigating some coagulation and haematologic profile of HIV positive patients on highly active antiretroviral therapy in patients attending clinic at the University of Benin Teaching Hospital. METHODS:This is a correlation study comprising fifty (50) HIV positive patients on HAART between 6 - 12 months as test subjects and fifty (50) HIV positive patients who have not began HAART as control subjects. Five millilitres of blood was withdrawn from each group by venepuncture into ethylene diaminetetracetic and sodium citrate anticoagulant containers. Platelet counts were estimated manually using ammonium oxalate solution, packed cell volume by the microhaematocrit method while Prothrombin Time (PT), Activated partial thrombroplastin time and fibrinogen concentration were done by methods described by Monica Chessbrough. RESULTS:This is presented as mean ± standard error of mean. There were reduction in PCV and platelet count between test and control subjects although not statistically significant (P> 0.05) while there was a significant increase in PT and PTTK between test and control groups (P<0.05). No significant change was observed in fibrinogen concentration in HIV patients on HAART and those not on HAART. CONCLUSION:HAART increases PT and PTTK in HIV infection.
journal_name
Pak J Med Scijournal_title
Pakistan journal of medical sciencesauthors
Osime EO,Oresanja OO,Okwara BUdoi
10.12669/pjms.316.7943subject
Has Abstractpub_date
2015-11-01 00:00:00pages
1533-6issue
6eissn
1682-024Xissn
1681-715Xpii
PJMS-31-1533journal_volume
31pub_type
杂志文章abstract：UNLABELLED:Objective : In this study, we aimed to investigate changes of peripheral Th17 and Treg cells frequencies in the newly-diagnosed Chronic Lymphocytic Leukemia (CLL) patients for 12 months. Methods : In this research, 50 CLL patients were enrolled. Circulating Th1, Th17 cells and CD4+CD25+Foxp3+Treg cells were ...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.305.5252
更新日期：2014-09-01 00:00:00
abstract：OBJECTIVE:The objective of the current study was to establish the reference ranges of haematological indices amongst five healthy infantile (<1 year) age groups. METHODOLOGY:It was a descriptive cross sectional study carried out at the Department of Haematology, Armed Forces Institute of Pathology (AFIP), Rawalpindi. ...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.292.3067
更新日期：2013-04-01 00:00:00
abstract：Objective:The study examines the level and source of perceived social support in pregnant adolescents and the factors related to their perception of social support. Methods:This descriptive study was conducted with the voluntary participation of 127 adolescent pregnant females who visited the Gynecology and Pediatric ...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.341.14221
更新日期：2018-01-01 00:00:00
abstract：OBJECTIVE:To explore the factors associated with preoperative epileptic seizure and surgical outcome in patients with cerebral gangliolioma (GG). METHODS:A total of 31 consecutive patients with pathologically confirmed ganglioglioma and surgically treated from January 2003 to June 2011 in West China Hospital of Sichua...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.302.4362
更新日期：2014-03-01 00:00:00
abstract：Objective:To evaluate the feasibility and safety of marking targeting biopsy (MTB) in the intraoperative localization value of colon polypectomy. Methods:The clinical data from patients with polyp of colon discovered under colonoscopy from January 2014 to January 2016 were retrospectively analyzed. A total of 87 patie...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.36.2.756
更新日期：2020-01-01 00:00:00
abstract：Objective:To compare the effects of simple saline dressings versus topical vancomycin dressings on Methicillin-resistant Staphylococcus Aureus positive chronic diabetic foot ulcers. Methods:It was quasi experimental study conducted in Combined Military Hospital Kohat and PNS-Shifa Hospital Karachi from 01 January 2017...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.35.4.368
更新日期：2019-07-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Cervical radiculopathy is a common neuro-musculo-skeletal disorder causing pain and disability. Traction is part of the evidence based manual physical therapy management due to its mechanical nature, type of traction and parameters related to its applicability and are still to be explored more ...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.321.8923
更新日期：2016-01-01 00:00:00
abstract：OBJECTIVE:To isolate Helicobacter pylori (HP) from the dental plaque of a selected group of children and to compare the oral and salivary findings of patients with those of a healthy control group. METHODS:A total of 70 children aged 5-15 years were included in this study. An intraoral examination was performed for ea...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.324.10034
更新日期：2016-07-01 00:00:00
abstract：Background and Objective:Brucellosis is an important zoonotic disease and a major public health problem in the Middle East countries including Saudi Arabia. This study has evaluated the seroprevalence of human brucellosis in Wadi Al Dawaser region of Central Saudi Arabia. Methods:The study was conducted for three year...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.35.1.55
更新日期：2019-01-01 00:00:00
abstract：Objectives:Urinary tract infections are the second most common bacterial infections occurring at all ages and both sexes. The increasing rate of antibiotic resistance is a global concern. The use of routinely used antibiotics is resulting in treatment failure. The objective of this study was to diagnose the urinary tra...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.36.3.1577
更新日期：2020-03-01 00:00:00
abstract：OBJECTIVES:To compare the scorings of real and standardized patients on physician communication skills. METHODS:Patient scoring (n=183) on physicians' communication skills was determined by 93 real and 90 standardized patients. Eighty physicians (42 specialists and 38 general physicians) in private practice were enrol...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.303.3255
更新日期：2014-05-01 00:00:00
abstract：OBJECTIVES:The aim of this study was to investigate the difference of liver function changes according to the liver regeneration rate after liver transplantation through blood tests. METHODS:Fifty donors, who underwent computed tomography (CT) 3D volumetry, were analyzed before and after liver transplantation. CT 3D v...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.311.5864
更新日期：2015-01-01 00:00:00
abstract：OBJECTIVE:Folate, vitamin B12 and iron are important vitamin and minerals which play role in the development of nervous system. The aim of this study was looking at the presence of folate, vitamin B12 and iron deficiency among patients with Primary nocturnal enuresis (PNE) and possible relation between the delay of cen...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.311.6424
更新日期：2015-01-01 00:00:00
abstract：OBJECTIVE:To evaluate the effect of colporrhaphy on sexual problems of women with pelvic organ prolapseis. METHODOLOGY:Sixty patients with pelvic organ prolapse (cystocele - rectocele) in a quasi-experimental study before and after treatment were included. Presence of pelvic organ prolapseis was assessed by examinatio...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.291.2610
更新日期：2013-01-01 00:00:00
abstract：UNLABELLED:Objective : Esophageal stethoscope has the advantage of being non-invasive, easily placed and capability to monitor the heart sound. This study was designed to determine whether the ratio of S1 to S2 analyzed by esophageal stethoscope and wireless bluetooth transmission can be accurate indicator that express...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.294.3639
更新日期：2013-07-01 00:00:00
abstract：OBJECTIVE:Helicobacter Pylori (H.pylori) is one of the most important causes of dyspepsia and diagnosis can be made by invasive or non-invasive methods. One of the non-invasive methods, H.pylori stool antigen test (HpSA) is simple, fast and relatively inexpensive. According to this view with regard to gastric biopsy as...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.291.2865
更新日期：2013-01-01 00:00:00
abstract：Objective:To investigate the clinical effect of ambroxol in the treatment of asthmatic bronchitis. Methods:One hundred and twenty patients with asthmatic bronchitis who were admitted to our hospital from June 2017 to August 2018 were selected as the research subjects and divided into a control group and an observation...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.36.3.1607
更新日期：2020-03-01 00:00:00
abstract：Objective:To explore the correlation of procalcitonin (PCT) and gelsolin (GSN) with the prognosis of urosepsis patients. Method:The data of 71 urosepsis patients from March 2015 to April 2019 who were admitted to and treated in Affiliated Hospital of Hebei University were analyzed and compared with those of 92 healthy...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.36.5.2143
更新日期：2020-07-01 00:00:00
abstract：:Blue rubber bleb nevus syndrome (BRBNS) is a rare syndrome characterized by multiple vascular malformations of varying size and appearance that present predominantly on the skin and within the gastrointestinal tract and, less often, in other internal organs. Gastrointestinal lesions of BRBNS can cause acute or chronic...
journal_title：Pakistan journal of medical sciences
pub_type：
doi：10.12669/pjms.311.5858
更新日期：2015-01-01 00:00:00
abstract：OBJECTIVE:Ventilator Associated Pneumonia (VAP) has an imperative place amongst nosocomial infections leading to increase morbidity and mortality rates. The present study aimed to determine risk factors for acquisition of ventilator- associated pneumonia in an intensive care unit (ICU). METHODS:A nested case-control s...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.295.3375
更新日期：2013-09-01 00:00:00
abstract：Objective:The study was performed to investigate the association of hypertension in pregnancy with prostasin gene polymorphism in Pakistani females. Methods:This case-control study was performed at University of Karachi, Pakistan from April 2018 to May 2019. A total of 160 females, including 90 hypertensives and 70 he...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.37.1.3666
更新日期：2021-01-01 00:00:00
abstract：OBJECTIVE:A Cross Sectional population based serological studies was conducted to determine the prevalence and associated risk factors for syphilis women with recurrent miscarriages. METHODS:Patient's 5ml whole blood was collected through venepuncture technique. Data were collected by all women answered a questionnair...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：
更新日期：2014-03-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:Helicobacter pylori (H. pylori) infection is cause of several gastrointestinal diseases in humans. Virulence genes of H. pylori are associated with severity of disease and vary geographically. The aim of present study was to detect H. pylori in formalin-fixed paraffin-embedded (FFPE) tissues a...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.332.12024
更新日期：2017-03-01 00:00:00
abstract：OBJECTIVE:The main objective of this study was to determine the predictors of frequent oral analgesic use among Rheumatoid Arthritis (RA) patients who were prescribed with the above medication on an 'as-needed' basis. METHODS:Patients with RA were recruited consecutively from the Rheumatology outpatient clinics in thi...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.305.5112
更新日期：2014-09-01 00:00:00
abstract：Objectives:To estimate the incidence of microvascular complications among subjects with type 2 diabetes at a tertiary care hospital. Methods:This retrospective longitudinal follow-up study assessed the data records of type 2 diabetic subjects who visited the outpatient department of Baqai Institute of Diabetology and ...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.345.15224
更新日期：2018-09-01 00:00:00
abstract：Objective:To find the perceived stress level and monetary burden in the thalassemia patients and their caregivers related to thalassemia treatment sessions. Methods:A descriptive cross sectional study was conducted at Rawalpindi Thalassemia Centre and Military Hospital Rawalpindi of six months' duration from November ...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.344.15420
更新日期：2018-07-01 00:00:00
abstract：:Doing a PhD (doctor of philosophy) for the sake of contribution to knowledge should give the student an immense enthusiasm through the PhD period. It is the time in one's life that one spends to "hit the nail on the head" in a specific area and topic of interest. A PhD consists mostly of hard work and tenacity; howeve...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.306.6378
更新日期：2014-11-01 00:00:00
abstract：Objective:To discuss the influence of coronary artery lesion of elderly patients with coronary heart disease (CHD) on left ventricular remodeling. Methods:Retrospective selection method was used to choose 80 elderly CHD patients who received coronary angiogram examination in Baoding First Central Hospital from January...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.35.1.225
更新日期：2019-01-01 00:00:00
abstract：OBJECTIVES:To evaluate the effect of low dose Albumin i.e. 4 grams per litre of ascitic fluid after large volume paracentesis (LVP) for the prevention of paracentesis induced circulatory dysfunction (PICD) related renal impairment in cirrhosis. METHODS:Case records of all patients with cirrhosis who underwent LVP from...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.313.7281
更新日期：2015-01-01 00:00:00
abstract：Objectives:The value of gastric residual volume (GRV) monitoring in ventilator-associated pneumonia (VAP) has frequently been questioned in the past years. In this trial, the effect of GRV on the frequency of VAP was evaluated in critically ill patients under mechanical ventilation. Methods:This descriptive study was ...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.36.2.1321
更新日期：2020-01-01 00:00:00
