Abstract：
OBJECTIVE:To find out the frequency of vitamin D deficiency and its relation with glucose parameters and the incidence of gestational diabetes (GDM). METHODOLOGY:Gestational diabetes was diagnosed with 75 gram oral glucose tolerance test. Forty-four pregnant women diagnosed with GDM and 78 non-GDM pregnant women were enrolled as case and control group, respectively in this descriptive study. Vitamin D status was classified as deficiency at ≤20 ng/ml for serum 25(OH)D concentrations. RESULTS:The mean ages were 33.4±5.2 (18-44) years and 29.7±4.1 (21-39) years, mean BMI was 30.6±5.9 kg/m² (19.5-46.1) and 25.9±4.4 kg/m2 (16.5-38) in case and control groups, respectively. The frequency of GDM was found 9.38%. The mean serum vitamin D levels in GDM group were significantly lower than in non-GDM subjects (p=0.07). A total of 56.8% of GDM patients were compared with 35.8% of control group which had Vitamin D deficiency and the difference was significant (p= 0.02). There was no significant association between vitamin D levels and fasting glucose, insulin and HbA1c. Vitamin D levels were inversely correlated with clothing style, parathyroid hormone levels, dental problems and muscle cramps. CONCLUSIONS:The association of maternal Vitamin D status with the markers of glucose metabolism in pregnancy needs prospective studies.
journal_name
Pak J Med Scijournal_title
Pakistan journal of medical sciencesauthors
Parildar H,Dogruk Unal A,Aksan Desteli G,Cigerli O,Guvener Demirag Ndoi
10.12669/pjms.291.2896subject
Has Abstractpub_date
2013-01-01 00:00:00pages
15-20issue
1eissn
1682-024Xissn
1681-715Xjournal_volume
29pub_type
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