Human cytomegalovirus glycoprotein B inhibits migration of breast cancer MDA-MB-231 cells and impairs TGF-β/Smad2/3 expression.

abstract：:Bovine lactoferricin P13 (LfcinB-P13) is a peptide derived from LfcinB. In the present study, the effect of LfcinB-P13 on the human liver cancer cell line SMMC7721 was investigated in vitro and in vivo. The results of the present study indicate that LfcinB-P13 significantly decreased SMMC7721 cell viability in vitro (...

journal_title：Oncology letters

authors： Meng L,Xu G,Li J,Liu W,Jia W,Ma J,Wei D

更新日期：2017-01-01 00:00:00

abstract：:Spontaneous remission (SR) in acute lymphoblastic leukemia (ALL) is a rare phenomenon, but the disease course and its underlying processes are of basic and clinical interest. Herein is reported the case of a pregnant, 31-year-old patient who developed ALL, followed by septic shock and SR of ALL. Information is summari...

journal_title：Oncology letters

authors： Höres T,Wendelin K,Schaefer-Eckart K

更新日期：2018-01-01 00:00:00

abstract：:The present study aimed to investigate the effects of overexpression of interferon-induced transmembrane protein 5 (IFITM5) and IFITM5 c.-14C>T mutation on osteogenic differentiation, and the proliferation, migration and invasion of SaOS2 cells. SaOS2 cells were transfected with plasmids containing wild type IFITM5 (W...

journal_title：Oncology letters

authors： Liu BY,Lu YQ,Han F,Wang Y,Mo XK,Han JX

更新日期：2017-01-01 00:00:00

abstract：:To define the correlation between BCR promoter DNA methylation and response to imatinib in chronic myeloid leukemia (CML), we investigated BCR promoter DNA methylation in three groups of subjects. The first group included chronic phase patients enrolled in an imatinib dose escalation trial. In the trial, patients who ...

journal_title：Oncology letters

authors： Koh Y,Kim DY,Park SH,Byun HM,Kim I,Yoon SS,Kim BK,Park E,Yang AS,Park S

更新日期：2011-01-01 00:00:00

abstract：:The objective of the present study was to investigate and analyze the epithelial-cadherin (E-cadherin) expression in invasive ductal carcinoma of the breast, and to analyze the associations between the expression and clinicopathological characteristics of lymph node metastasis and the prognosis of breast cancer. The i...

journal_title：Oncology letters

authors： Yang L,Wang XW,Zhu LP,Wang HL,Wang B,Zhao Q,Wang XY

更新日期：2018-08-01 00:00:00

abstract：:Nordihydroguaiaretic acid (NDGA) and its derivatives possess anti-cancer effects on various types of cancer via the induction of apoptosis or cell cycle arrest. This study proved that NDGA inhibited cervical cancer SiHa cell growth and induced cell cycle arrest at the G(1) phase, which may be a consequence of cell cyc...

journal_title：Oncology letters

authors： Gao P,Zhai F,Guan L,Zheng J

更新日期：2011-01-01 00:00:00

abstract：:Hepatocyte growth factor (HGF) expression is a poor prognostic factor in various types of cancer. Expression levels of HGF have been reported to be regulated by shorter poly(dA) sequences in the promoter region. In the present study, the poly(dA) mononucleotide tract in various types of human cancer cell lines was exa...

journal_title：Oncology letters

authors： Sakai K,Takeda M,Okamoto I,Nakagawa K,Nishio K

更新日期：2015-01-01 00:00:00

abstract：:Colorectal cancer (CRC) is one of the leading causes of mortality among men and women. Chemo-resistance, adverse effects and disease recurrence are major challenges in the development of effective cancer therapeutics. Substantial literature on this subject highlights that populations consuming diets rich in fibers, fr...

journal_title：Oncology letters

authors： Ahmed K,Zaidi SF,Cui ZG,Zhou D,Saeed SA,Inadera H

更新日期：2019-07-01 00:00:00

abstract：:The long non-coding RNA (lncRNA) plasmacytoma variant translocation 1 (PVT1) has been identified as an oncogene in numerous diseases, and aberrant lncRNA PVT1 expression has been associated with the development of cancer. However, the underlying mechanism by which lncRNA PVT1 affects cell invasion in esophageal cancer...

journal_title：Oncology letters

authors： Zheng X,Hu H,Li S

更新日期：2016-10-01 00:00:00

abstract：:Gastrinoma is a gastrin-secreting tumor that is associated with Zollinger-Ellison syndrome. The majority of cases occur in the pancreas, followed by the duodenum. Early diagnosis is difficult due to the relative rarity of the tumor and the lack of specific symptoms. In the current study, a 68-year-old female patient p...

journal_title：Oncology letters

authors： Zhang WD,Liu DR,Wang P,Zhao JG,Wang ZF,Chen LI

更新日期：2016-05-01 00:00:00

abstract：:Follicular lymphoma (FL) occurs primarily in the gastrointestinal tract, with the stomach being one of the rarest sites. According to the literature, <20 cases of primary gastric FL have been reported, with the number of cases with detailed pathological descriptions being even less. The aim of the present study was to...

journal_title：Oncology letters

authors： Na HY,Kim YA,Lee C,Choe JY,Shin SA,Shim JW,Min SK,Kim HJ,Han JH,Kim JE

更新日期：2018-07-01 00:00:00

abstract：:In patients with diffuse large B-cell lymphoma (DLBCL) classified as high-intermediate risk or high risk using the International Prognosis Index, the efficacy of high-dose chemotherapy combined with upfront autologous stem cell transplantation (HDT/ASCT) remains controversial in the rituximab era. In the present study...

journal_title：Oncology letters

authors： Nakaya A,Fujita S,Satake A,Nakanishi T,Azuma Y,Tsubokura Y,Hotta M,Yoshimura H,Ishii K,Ito T,Nomura S

更新日期：2017-09-01 00:00:00

abstract：:The high mobility group A1 (HMGA1) protein is associated with poor prognosis in patients with a wide range of cancers. However, the affect of HMGA1 on the risk of mortality from breast cancer (BC) has not been fully characterized. In the present retrospective multiple center study, the HMGA1 expression level was deter...

journal_title：Oncology letters

authors： Zhang S,Lei R,Wu J,Shan J,Hu Z,Chen L,Ren X,Yao L,Wang J,Wang X

更新日期：2017-11-01 00:00:00

abstract：:The present study aimed to clarify the association between kinesin family member 11 (KIF11) and human breast cancer, and the effect of KIF11 on breast cancer cell progression. Western blot analysis, reverse transcription-quantitative polymerase chain reaction (RT-qPCR) analysis, retroviral infection, immunohistochemis...

journal_title：Oncology letters

authors： Pei YY,Li GC,Ran J,Wei FX

更新日期：2017-12-01 00:00:00

abstract：:The present study aimed to analyze the imaging features and pathological basis of primary hepatic neuroendocrine carcinoma (PHNEC). A retrospective analysis of the imaging and pathological features of nine PHNEC cases was carried out at The Second Xiangya Hospital of Central South University (Changsha, China). The nin...

journal_title：Oncology letters

authors： Chen Z,Xiao HE,Ramchandra P,Huang HJ

更新日期：2014-04-01 00:00:00

abstract：:The present study aimed to ascertain the significance of topoisomerase II α (TOP2A) and minichromosome maintenance protein (MCM) 2 expression in anal carcinoma. A total of 75 anal lesions were retrieved from the files of the Department of Pathology of Barretos Cancer Hospital (Barretos, Brazil) in order to verify the ...

journal_title：Oncology letters

authors： Scapulatempo-Neto C,Veo C,Fregnani JHTG,Lorenzi A,Mafra A,Melani AGF,Loaiza EAA,Rosa LAR,de Oliveira CM,Levi JE,Longatto-Filho A

更新日期：2017-03-01 00:00:00

abstract：:This study aimed to determine the relationship between human papillomavirus (HPV) and nuclear factor-κB (NF-κB) in cervical cancer using 62 tissues of cervical cancer, and to compare the findings to penile cancer. HPV-DNA integration is a crucial factor for malignant transformation in cervical cancer and can be identi...

journal_title：Oncology letters

authors： Senba M,Buziba N,Mori N,Fujita S,Morimoto K,Wada A,Toriyama K

更新日期：2011-01-01 00:00:00

abstract：:Solitary fibrous tumors (SFTs) are uncommon, with the pleura as a site of predilection. Central nervous system SFTs, particularly intracranial SFTs, are extremely rare. The lesions are generally benign and localized, and surgery is the main therapeutic solution. The current study reports the cases of a patient who pre...

journal_title：Oncology letters

authors： Wang ZY,Qiu K,Ma YH,Wang XT,Bao JJ,Zhang ZF,Liu XZ

更新日期：2016-02-01 00:00:00

abstract：:[This retracts the article DOI: 10.3892/ol.2016.4607.]. ...

journal_title：Oncology letters

authors： Li L,Mao X,Qin X,Zhou M,Xing H,Dong F,Jiang X,Zhuang W

更新日期：2019-05-01 00:00:00

abstract：:Our previous study demonstrated that the 2-benzyloxybenzaldehyde analog CCY-1a-E2 is a potent compound against HL-60 human leukemia cell lines. To investigate the potential therapeutic application of CCY-1a-E2 for leukemia, we analyzed the antileukemic effects and safety of CCY-1a-E2 in the BALB/c mouse WEHI-3 allogra...

journal_title：Oncology letters

authors： Lin C,Yang JS,Tsai SC,Lin CF,Lee MR

更新日期：2013-03-01 00:00:00

abstract：:Cholangiocarcinoma (CCA) is a primary malignancy, which is often diagnosed as locally advanced or metastatic. Previous studies have revealed genomic characteristics of CCA in Western patients, however comprehensive genomic features of CCA in Chinese patients have not been well understood. To explore the specific genom...

journal_title：Oncology letters

authors： Tian W,Hu W,Shi X,Liu P,Ma X,Zhao W,Qu L,Zhang S,Shi W,Liu A,Cao J

更新日期：2020-04-01 00:00:00

abstract：:Cervical cancer is the third most common malignancy worldwide, accounting for 250,000 mortalities annually. Notch1, an important regulator of cell-fate decisions and differentiation, has been found to be overexpressed in certain types of cancer. However, the role of Notch1 in cervical carcinogenesis remains unclear. I...

journal_title：Oncology letters

authors： Sun Y,Zhang R,Zhou S,Ji Y

更新日期：2015-06-01 00:00:00

abstract：:Primary hepatic lymphoma (PHL) is an uncommon lymphoid tumor with varied clinical features and treatment outcome. In the present study, the case of a 56-year-old patient with PHL and no clinical presentation was reported. During a routine physical examination, multiple hypodense nodules were incidentally detected in r...

journal_title：Oncology letters

authors： Zhang KJ,Chen S,Chen JL,Dong LH

更新日期：2015-04-01 00:00:00

abstract：:Pancreatic cancer is one of the most frequently occurring malignancies worldwide and it is the fourth most common cause of cancer-associated mortality in Western countries. Thalidomide (THD) plays an important role in tumor therapy, as it is able to promote early stage apoptosis and inhibit the process of angiogenesis...

journal_title：Oncology letters

authors： Qiao Z,Yuan J,Shen J,Wang C,He Z,Hu Y,Zhang M,Xu C

更新日期：2015-05-01 00:00:00

abstract：:Angioleiomyoma of the nasal cavity is extremely rare. There are only a small number of studies in the literature that demonstrate that the estrogen receptor (ER) and progesterone receptor (PR) are expressed in angioleiomyoma, and the results from these studies are inconsistent. The present study identified 6 patients ...

journal_title：Oncology letters

authors： Zhu G,Xiao D,Sun P

更新日期：2016-04-01 00:00:00

abstract：:The present study aimed to explore the expression of microRNA (miRNA or miR) in drug-resistant and drug-sensitive ovarian cancer cell lines, and to seek the potential therapeutic target of ovarian cancer drug-resistant mechanism in order to improve drug resistance by altering miRNA levels. The drug-resistant character...

journal_title：Oncology letters

authors： Liu J,Wu X,Liu H,Liang Y,Gao X,Cai Z,Wang W,Zhang H

更新日期：2016-09-01 00:00:00

abstract：:Poly(ADP-Ribose) polymerase family member 9 (PARP9) promotes the proliferation, survival and chemotherapy resistance in lymphoma and prostate cancer. The expression and function of PARP9 in human breast cancer remains unknown. In the present study, it was demonstrated that PARP9 is frequently overexpressed in human br...

journal_title：Oncology letters

authors： Tang X,Zhang H,Long Y,Hua H,Jiang Y,Jing J

更新日期：2018-09-01 00:00:00

abstract：:The present study was performed to quantify tumor neo-vessels, macrophages and fibroblasts in the tumor microenvironment of hepatocellular carcinoma (HCC) and explore the prognostic factors of HCC. The distribution of tumor neo-vessels, macrophages and fibroblasts was quantified by immunohistochemistry and inverted mi...

journal_title：Oncology letters

authors： Fang M,Yuan J,Chen M,Sun Z,Liu L,Cheng G,Ying H,Yang S,Chen M

更新日期：2018-04-01 00:00:00

abstract：:Malignant mesothelioma in the mediastinum is rare and the majority of known cases have been reported as 'localized mesothelioma'. The present study reports a case of an upper mediastinal tumor, which was diagnosed through thoracoscopic surgery and surgical biopsies of the mass. A computed tomography scan revealed a gi...

journal_title：Oncology letters

authors： Zhang S,Song P,Zhang B

更新日期：2013-07-01 00:00:00

abstract：:Effects of Rapamycin on the proliferation and apoptosis of retinoblastoma cells through the phosphatidylinositol 3-hydroxy kinase (PI3K)/protein kinase B (AKT) signaling pathway were studied. The retinoblastoma Y79 cells were selected and divided into negative control group (NC group), 0.2 µM Rapamycin group and 0.4 µ...

journal_title：Oncology letters

authors： Yao J,Xu M,Liu Z

更新日期：2020-04-01 00:00:00