Complete response to comprehensive treatment of a primary hepatic diffuse large B cell lymphoma: A case report.

abstract：:Angiosarcoma is a rare and deadly malignancy originating from the vascular endothelial cells. Surgery is the most effective method to cure this disease, but for metastatic angiosarcoma, a chemotherapy-based treatment is the main therapeutic choice. However, there is currently no standard chemotherapy regimen. The curr...

journal_title：Oncology letters

authors： Ye J,Li XF,Wang YD,Yuan Y

更新日期：2015-04-01 00:00:00

abstract：:Chemotherapy failure remains a challenge when treating patients with acute myeloid leukemia (AML), who often suffer from persistent or relapsed disease. The multidrug resistance (MDR) mediated by efflux transporters of the ATP binding cassette (ABC) superfamily is a major obstacle for successful chemotherapy. The pres...

journal_title：Oncology letters

authors： Liu B,Li LJ,Gong X,Zhang W,Zhang H,Zhao L

更新日期：2018-05-01 00:00:00

abstract：:Approximately 34-86% of neoplasms of the salivary glands are located in the parotid gland and parotidectomy is the first-line treatment for parotid gland tumors. Frey syndrome and cosmetic deformity are common complications experienced by patients following parotidectomy and the sternocleidomastoid muscle flap (SCMF) ...

journal_title：Oncology letters

authors： Liu DY,Tian XJ,Li C,Sun SS,Xiong YH,Zeng XT

更新日期：2013-04-01 00:00:00

abstract：:Correlation between CT features of adrenocortical and adrenal medullary tumors and the expression of miR-96 in serum were investigated. A total of 230 patients with adrenocortical tumors and 194 patients with adrenal medullary tumors were selected in Dongying People's Hospital from August 2013 to August 2017. The two ...

journal_title：Oncology letters

authors： Xu Y,Wang Z,Bi Y,Duan Z,Yue X

更新日期：2018-08-01 00:00:00

abstract：:Cervical cancer is the third most common malignancy worldwide, accounting for 250,000 mortalities annually. Notch1, an important regulator of cell-fate decisions and differentiation, has been found to be overexpressed in certain types of cancer. However, the role of Notch1 in cervical carcinogenesis remains unclear. I...

journal_title：Oncology letters

authors： Sun Y,Zhang R,Zhou S,Ji Y

更新日期：2015-06-01 00:00:00

abstract：:Wilms tumor (WT) is the most common pediatric renal malignancy. A recent ontogenic model suggests that undifferentiated tumor state, and hence poor prognosis, in WT is determined by stabilization of β-catenin in the nucleus. Forkhead box M1 (FOXM1) is a downstream component of the Wnt pathway and promotes nuclear loca...

journal_title：Oncology letters

authors： Apelt N,Hubertus J,Mayr D,Graf N,Furtwängler R,Von Schweinitz D,Kappler R

更新日期：2016-10-01 00:00:00

abstract：:Extragastrointestinal stromal tumors (EGISTs) are relatively rare soft tissue neoplasms arising from the extra gastrointestinal tract. The current study presents a case of primary EGIST of the prostate observed in a 55-year-old male. Imaging studies showed a 10×10.5×9.5-cm prostate mass. On histological observation, t...

journal_title：Oncology letters

authors： Liu S,Yu Q,Han W,Qi L,Zu X,Zeng F,Xie Y,Liu J

更新日期：2014-06-01 00:00:00

abstract：:Changes in filamin A (FLNa) expression contribute to the development and progression of numerous malignancies. However, in vitro studies of breast cancer have shown conflicting results. Thus, the present study aimed to detect the expression of FLNa in breast cancer tissue samples and the association with clinicopathol...

journal_title：Oncology letters

authors： Tian HM,Liu XH,Han W,Zhao LL,Yuan B,Yuan CJ

更新日期：2013-09-01 00:00:00

abstract：:Intrahepatic cholangiocarcinoma (ICC) is an aggressive type of cancer, and its incidence and mortality rates are increasing worldwide. Mortalin is a highly conserved chaperone protein involved in multiple pathological and physiological processes, including anti-apoptosis, carcinogenesis and metastasis. The Bcl-2 famil...

journal_title：Oncology letters

authors： Kang Q,Zou H,Yang X,Cai JB,Liu LX,Xie N,Wang LM,Li YH,Zhang XW

更新日期：2018-02-01 00:00:00

abstract：:Deoxypodophyllotoxin (DPPT) is extracted and separated from citrus-related plants, including Podophyllum (P.) peltatum, P. pleianthum, P. emodi (also called P. hexandrum) and Diphylleia grayi. DPPT has significant antitumor and antiviral activity. However, due to its strong toxicity and side effects, its use is limite...

journal_title：Oncology letters

authors： Hu S,Zhou Q,Wu WR,Duan YX,Gao ZY,Li YW,Lu Q

更新日期：2016-10-01 00:00:00

abstract：:Cross-talk between competing endogenous RNAs (ceRNAs) play key roles in tumor development. In this study, we performed exon-level expression profiling on 26 glioblastomas (GBMs) and 6 controls to identify long non-coding RNAs (lncRNAs) of GBM initiation and progression using lncRNA-mediated ceRNA network (LMCN). The m...

journal_title：Oncology letters

authors： Zan XY,Li L

更新日期：2019-05-01 00:00:00

abstract：:Ulcerative colitis (UC) is thought to be associated with precancerous lesions that can ultimately lead to colon cancer. Therefore, diagnostic markers for colorectal dysplasia and cancer are urgently needed for patients with UC. Stathmin 1 (STMN1) is a novel cancer biomarker that is also a novel target for treatment in...

journal_title：Oncology letters

authors： Osone K,Yokobori T,Katayama C,Takahashi R,Kato R,Tatsuski H,Takada T,Yajima R,Motegi Y,Ogawa H,Fujii T,Ojima H,Nakamura J,Yao T,Shirabe K,Kuwano H

更新日期：2019-11-01 00:00:00

abstract：:Although previous studies have demonstrated that dysregulation of microRNA (miR)-126 is associated with the progression of several types of cancer, including lung cancer, the relationship between miR-126 and lung cancer metastasis remains unclear. SPC-A1 lung cancer cells were transfected with miR-126 mimic and negati...

journal_title：Oncology letters

authors： Jia Z,Zhang Y,Xu Q,Guo W,Guo A

更新日期：2018-05-01 00:00:00

abstract：:The detection and characterisation of tumour-derived circulating epithelial tumor cells (CETCs) or circulating tumor cells (CTCs) have been a main focus of basic oncological research over previous years. Numerous studies in the past decade have shown that CTCs are a promising tool for the estimation of the risk for me...

journal_title：Oncology letters

authors： Willecke-Hochmuth R,Pachmann K,Drevs J

更新日期：2016-09-01 00:00:00

abstract：:The development of upper tract urothelial carcinoma (UTUC) has been associated with the ingestion of aristolochic acid (AA) in Chinese herbs. The tumors are more malignant and patients have a worse prognosis in China compared with that in Western countries. Recently, whole-genome and exome sequencing of AA-associated ...

journal_title：Oncology letters

authors： Wang Y,Zhang JX,Wang SF,Zhang Y,He HY

更新日期：2020-12-01 00:00:00

abstract：:The prognosis for patients with head and neck cancer (HNC) remains poor, owing to uncontrolled tumor invasion and metastasis. Epithelial-mesenchymal transition (EMT) serves an important role in this invasion and metastasis, and transient receptor potential polycystic 2 (TRPP2) enhances metastasis and invasion by regul...

journal_title：Oncology letters

authors： Wang C,Chen L,Huang Y,Li K,Jinye A,Fan T,Zhao R,Xia X,Shen B,Du J,Liu Y

更新日期：2019-02-01 00:00:00

abstract：:A previous study reported the decreased expression of long non-coding RNA mortal obligate RNA transcript (lncRNA MORT) in 16 types of cancer, while the functionality of lncRNA MORT in cancer biology remains unknown. Therefore, the present study was conducted to characterize the functionality of lncRNA MORT in prostate...

journal_title：Oncology letters

authors： Shi Z,Guo F,Jia D,Huang J,Chen J,Sun M,Qi F,Liang C

更新日期：2019-10-01 00:00:00

abstract：:The Na+/K+-ATPase α subunit is highly expressed in malignant cells. Ouabain, a cardioactive glycoside, binds to the Na+/K+-ATPase α subunit and inhibits the activity of Na+/K+-ATPase. In the present study, the effect of ouabain on the migration of A549 cells was analyzed using the wound healing and transwell chamber m...

journal_title：Oncology letters

authors： Liu N,Li Y,Su S,Wang N,Wang H,Li J

更新日期：2013-08-01 00:00:00

abstract：:We investigated whether treatment package time was significantly associated with survival outcomes of resectable locally-advanced laryngeal squamous cell carcinoma in patients who consecutively underwent various treatments, including surgery alone and salvage surgery for residual tumor. A total of 100 patients with cl...

journal_title：Oncology letters

authors： Suzuki H,Terada H,Hanai N,Nishikawa D,Koide Y,Beppu S,Kodaira T,Tachibana H,Koide Y,Tanaka H,Hasegawa Y

更新日期：2019-01-01 00:00:00

abstract：:Carbonyl reductase 1 (CBR1) is theorized to participate in various cellular processes, such as signal transduction, apoptosis, carcinogenesis and drug resistance, and is highly expressed in certain malignancies, including lung tumors. Several studies have provided evidence that gene polymorphisms may affect susceptibi...

journal_title：Oncology letters

authors： Guo Y,Shen Y,Xia Y,Gu J

更新日期：2017-11-01 00:00:00

abstract：:Berberine is sourced from multiple medicinal herb resources and is easy to extract. With the advantages of low price, safety and convenience, berberine may have potential for wide clinical use. The present study aimed to investigate whether berberine inhibited the viability of colon cancer and whether it regulated the...

journal_title：Oncology letters

authors： Lü Y,Han B,Yu H,Cui Z,Li Z,Wang J

更新日期：2018-04-01 00:00:00

abstract：:A disintegrin and metalloproteinase 9 (ADAM9) is a member of the transmembrane ADAM family. It is expressed in different types of solid cancer and promotes tumor invasiveness. To the best of our knowledge, the present study was the first to examine ADAM9 expression in vestibular schwannomas (VS) from patients with and...

journal_title：Oncology letters

authors： Breun M,Schwerdtfeger A,Martellotta DD,Kessler AF,Monoranu CM,Matthies C,Löhr M,Hagemann C

更新日期：2020-03-01 00:00:00

abstract：:The present study aimed to investigate the feasibility of using ecto-mesenchymal stem cell (EMSC)-derived dendritic cells (DCs) for glioma immunotherapy following infection by a recombinant adenovirus containing the melanoma-associated antigen D4a (MAGE-D4a) gene. The ex vivo cultured EMSCs were infected by the adenov...

journal_title：Oncology letters

authors： Hu S,Li B,Shen X,Zhang R,Gao D,Guo Q,Jin Y,Fei Z

更新日期：2016-04-01 00:00:00

abstract：:The aim of this study was to objectively evaluate the benefits of laparoscopically assisted vaginal radical hysterectomy and lymphadenectomy for early-stage cervical cancer. Clinical data were prospectively collected from patients with IA-IIB cervical cancer who underwent laparoscopically assisted vaginal radical hyst...

journal_title：Oncology letters

authors： Hou CY,Li XL,Jiang F,Gong RJ,Guo XY,Yao YQ

更新日期：2011-07-01 00:00:00

abstract：:An elevated neutrophil to lymphocyte ratio (NLR) has been reported to be associated with the pathological response to neoadjuvant therapies in numerous types of cancer. The aim of the current study was to clarify the association between pre-treatment NLR and the pathological response to preoperative chemoradiotherapy ...

journal_title：Oncology letters

authors： Hasegawa S,Eguchi H,Tomokuni A,Tomimaru Y,Asaoka T,Wada H,Hama N,Kawamoto K,Kobayashi S,Marubashi S,Konnno M,Ishii H,Mori M,Doki Y,Nagano H

更新日期：2016-02-01 00:00:00

abstract：:For osteoblastoma, with its predilection for the spinal column and appendicular skeleton, the skull is an unusual site, and paranasal sinus involvement is very rare. Herein, we report on a case in which the disease was located within the sphenoid bone. To the best of our knowledge, this is the 4th reported case of ost...

journal_title：Oncology letters

authors： Kukwa W,Oziębło A,Oecińska A,Czarnecka AM,Włodarski K,Kukwa A

更新日期：2010-03-01 00:00:00

abstract：:The present study aimed to investigate the effects of Na+/H+ exchanger regulatory factor 1 (NHERF1) gene knockdown, using short-hairpin RNA (shRNA), on the malignant behaviors of prostate cancer cells. A pSuper.puro NHERF1 shRNA vector was transfected into PC-3M prostate cancer cells using Lipofectamine 2000. Stable c...

journal_title：Oncology letters

authors： Ma Q,Jiao Y,Hao Y,Yan S,Lyu N,Gao H,Li D,Liu Q,Zheng J,Song N

更新日期：2016-02-01 00:00:00

abstract：:Correlation of APOBEC3G expression with liver function indexes of patients with chronic hepatitis B and its expression in chronic hepatitis B, liver cirrhosis and liver cancer were investigated to evaluated the significance of APOBEC3G. Fifty-eight patients with chronic hepatitis B were selected, including 20 cases of...

journal_title：Oncology letters

authors： Ni L,Li C,Li Y

更新日期：2020-03-01 00:00:00

abstract：:Cervical cancer pathogenesis is regulated by numerous factors, including microRNAs. MicroRNA 1246 (miR-1246) has been shown to serve a role in cervical cancer tumorigenesis. However, the mechanisms through which miR-1246 exerts its oncogenic effects are largely unknown. The aim of the current study was to evaluate the...

journal_title：Oncology letters

authors： Du P,Lai YH,Yao DS,Chen JY,Ding N

更新日期：2019-09-01 00:00:00

abstract：:The flavonoid compound scutellarin (Scu) is a traditional Chinese medicine used to treat a variety of diseases; however, the use of scutellarein (Scue), the hydrolysate of Scu, and its mechanisms of action in Alzheimer's disease (AD) have not been fully elucidated. In the present study, the effects of Scue on amyloid ...

journal_title：Oncology letters

authors： Huang XW,Xu Y,Sui X,Lin H,Xu JM,Han D,Ye DD,Lv GF,Liu YX,Qu XB,Duan MH

更新日期：2019-06-01 00:00:00