Primary gastrointestinal stromal tumor of the prostate: A case report and literature review.

abstract：:The aim of the present study was to identify genes that may serve as markers for breast cancer prognosis by constructing a gene co-expression network and mining modules associated with survival. Two gene expression datasets of breast cancer were downloaded from ArrayExpress and genes from these datasets with a coeffic...

journal_title：Oncology letters

authors： Shi H,Zhang L,Qu Y,Hou L,Wang L,Zheng M

更新日期：2017-10-01 00:00:00

abstract：:The monolocular cystic formation associated with gallbladder carcinoma is an extremely rare condition. A 79-year-old female suffering from upper abdominal pain and distention was admitted to our hospital. Ultrasonography and computed tomography revealed a monolocular cyst with an irregular wall thickness of 15 cm in d...

journal_title：Oncology letters

authors： Hiraki M,Yakushiji H,Hashiguchi K,Harada S,Kohya N,Kai K,Yamaguchi K,Mori D,Irie K,Tokunaga O,Noshiro H,Miyazaki K

更新日期：2010-11-01 00:00:00

abstract：:Salidroside is one of the most potent compounds extracted from the plant Rhodiola rosea, and its cardiovascular protective effects have been studied extensively. However, the role of salidroside in human ovarian carcinoma remains unknown. The aim of the current study was to investigate the effects of salidroside on th...

journal_title：Oncology letters

authors： Yu G,Li N,Zhao Y,Wang W,Feng XL

更新日期：2018-05-01 00:00:00

abstract：:A disintegrin and metalloproteinase 9 (ADAM9) is a member of the transmembrane ADAM family. It is expressed in different types of solid cancer and promotes tumor invasiveness. To the best of our knowledge, the present study was the first to examine ADAM9 expression in vestibular schwannomas (VS) from patients with and...

journal_title：Oncology letters

authors： Breun M,Schwerdtfeger A,Martellotta DD,Kessler AF,Monoranu CM,Matthies C,Löhr M,Hagemann C

更新日期：2020-03-01 00:00:00

abstract：:The existence of cancer stem cells (CSCs) is central to the pathogenesis and therapeutic target of human hepatocellular carcinoma. The aim of this study was to investigate the effects of casticin on epithelial-mesenchymal transition (EMT) of liver cancer stem cells (LCSCs) derived from the SMMC-7721 cell line. Our res...

journal_title：Oncology letters

authors： He M,Cao XC,He GC,Sheng XF,Ai XH,Wu YH

更新日期：2014-05-01 00:00:00

abstract：:The present study aimed to evaluate regional liver function impairment following transcatheter arterial chemoembolization (TACE), assessed by magnetic resonance imaging (MRI) enhanced by gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid (Gd-EOB-DTPA). Additionally, this study evaluated the associations betwe...

journal_title：Oncology letters

authors： Xiao YD,Paudel R,Liu H,Zhang B,Ma C,Zhou SK

更新日期：2015-03-01 00:00:00

abstract：:The present study examined the association between squamous cell carcinoma antigen (SCCA) expression and the response of patients with cervical cancer to docetaxel-carboplatin (DC) combination chemotherapy, in order to determine the prognostic potential of SCCA expression. A total of 21 patients were enrolled with sta...

journal_title：Oncology letters

authors： Chen P,Jiao L,Wang DB

更新日期：2017-03-01 00:00:00

abstract：:Gefitinib is a selective inhibitor of the tyrosine kinase epidermal growth factor receptor, which inhibits tumor pathogenesis, metastasis and angiogenesis, as well as promoting apoptosis. Therefore, gefitinib presents an effective drug for the targeted therapy of lung cancer. However, the underlying mechanisms by whic...

journal_title：Oncology letters

authors： Zhao ZQ,Yu ZY,Li J,Ouyang XN

更新日期：2016-07-01 00:00:00

abstract：:Although bulk high-throughput genomic profiling studies have led to a significant increase in the understanding of cancer biology, there is increasing awareness that bulk profiling approaches do not completely elucidate tumor heterogeneity. Single-cell genomic profiling enables the distinction of tumor heterogeneity, ...

journal_title：Oncology letters

authors： Yan B,Hu Y,Ban KHK,Tiang Z,Ng C,Lee J,Tan W,Chiu L,Tan TW,Seah E,Ng CH,Chng WJ,Foo R

更新日期：2017-03-01 00:00:00

abstract：:The incidence of synchronous multiple primary lung cancer (MPLC) is increasing. However, present diagnostic methods are unable to satisfy the individualized treatment requirements of patients with MPLC. The present study aimed to establish a quantitative mathematical model and analyze its diagnostic value for distingu...

journal_title：Oncology letters

authors： Chen D,Mei L,Zhou Y,Shen C,Xu H,Niu Z,Che G

更新日期：2015-03-01 00:00:00

abstract：:In the present study, we analyzed the supra-additive effect of oxaliplatin in combination with gemcitabine on terminal colorectal cancer and its influence on high-mobility group box 1 (HMGB1) expression. A total of 86 patients with terminal colorectal cancer were enrolled in this study. Patients received oxaliplatin i...

journal_title：Oncology letters

authors： Wen S,Du X,Gou Y,Jiang L

更新日期：2016-11-01 00:00:00

abstract：:Keratocystic odontogenic tumors (KCOTs) and ameloblastomas are benign odontogenic tumors that primarily occur in the molar region of the mandible. However, it is uncommon for these tumors to arise simultaneously in a patient's jaw. The present study reported the diagnostic process and features of a rare case of the si...

journal_title：Oncology letters

authors： Gamoh S,Akiyama H,Tominaga K,Nakajima M,Kakudo K,Tanaka A,Shimizutani K

更新日期：2015-08-01 00:00:00

abstract：:In order to study the influence and mechanism of miR-544a on the self-renewal ability of lung cancer stem cells, TargetScan was used to predict the target gene of miR-544a. A luciferase reporter system and western blotting were used to validate the target genes identified by TargetScan. 95C and 95D low and high metast...

journal_title：Oncology letters

authors： Mo XM,Li HH,Liu M,Li YT

更新日期：2014-10-01 00:00:00

abstract：:Sirtuin 3 (Sirt3) is an important member of the sirtuin protein family. It is a deacetylase that was previously reported to modulate the level of reactive oxygen species (ROS) production and limit the extent of oxidative damage in cellular components. As an important member of the class III type of histone deacetylase...

journal_title：Oncology letters

authors： Shi Y,He R,Yang Y,He Y,Zhan L,Wei B

更新日期：2020-11-01 00:00:00

abstract：:The present study aimed to elucidate the role of cluster of differentiation (CD)8+, CD4+, natural killer (NK), and myeloid (CD11b+) cells in the course of the growth and rejection of experimental major histocompatibility complex (MHC) class I-deficient, HPV16 E6/E7-associated TC-1/A9 tumors in mice. Stable mouse lines...

journal_title：Oncology letters

authors： Indrová M,Rossowska J,Pajtasz-Piasecka E,Mikyšková R,Richter J,Rosina J,Sedlacek R,Fišerová A

更新日期：2018-03-01 00:00:00

abstract：:Effective therapies are limited for pancreatic cancer, particularly for those with distant tumour metastases. Therefore, more individualised drug screening is urgently required. Next-generation sequencing (NGS) is a powerful tool to investigate the genomic landscape of patients and the mechanism of drug response, whic...

journal_title：Oncology letters

authors： Guan Z,Lan H,Sun D,Wang X,Jin K

更新日期：2019-02-01 00:00:00

abstract：:Previous studies have demonstrated that C-X-C chemokine receptor type 7 (CXCR7) regulates papillary thyroid carcinoma (PTC) growth and metastasis; however, the molecular mechanisms underlying this regulation remain unclear. In the present study, the protein expression profiles of the PTC cell line GLAG-66 and GLAG-66 ...

journal_title：Oncology letters

authors： Zhang H,Yang L,Liu Z,Liu C,Teng X,Zhang L,Yin B,Liu Z

更新日期：2017-09-01 00:00:00

abstract：:Patients with chronic inflammatory bowel disease have an increased risk of colorectal cancer, and the differentiation between neoplastic and inflammatory lesions often poses a clinical dilemma. The aim of the present study was to investigate whether diffusion-weighted (DW) magnetic resonance (MR) enterography with ult...

journal_title：Oncology letters

authors： Yu H,Feng C,Wang Z,Li J,Wang Y,Hu X,Li Z,Shen Y,Hu D

更新日期：2019-08-01 00:00:00

abstract：:Matrix metalloproteinases (MMPs) are enzymes for extracellular matrix remodeling that are involved in tumor growth, progression and metastasis. Among them, MMP-9 has been implicated in tumor angiogenesis. Tissue inhibitor of matrix metalloproteinase (TIMP)-2, a member of the family of MMP inhibitors, induces apoptosis...

journal_title：Oncology letters

authors： Wajner SM,Capp C,Brasil BA,Meurer L,Maia AL

更新日期：2014-03-01 00:00:00

abstract：:Carcinogenesis is characterized by an abnormal regulation of the cell cycle. Regulators of the cell cycle such as cyclin E play an important role in neoplasia and may be correlated with prognosis. The clinical significance of the expression of cyclin E in stage III colorectal carcinoma has not yet been investigated. T...

journal_title：Oncology letters

authors： Rath-Wolfson L,Bergman M,Ori Y,Goldman A,Ram E,Koren R,Salman H

更新日期：2013-01-01 00:00:00

abstract：:MicroRNA (MiR)-506 serves a vital role in several types of cancer. However, the role of miR-506 in bladder cancer (BCa) progression remains to be investigated. The present study demonstrated that miR-506 expression was downregulated in BCa tissues and cell lines. Meanwhile, overexpression of miR-506 inhibited cell pro...

journal_title：Oncology letters

authors： Hou Y

更新日期：2019-01-01 00:00:00

abstract：:Aryl hydrocarbon receptor nuclear translocator (ARNT) is a transcription factor that has been reported to play a vital role in regulating glycolysis, angiogenesis and apoptosis. Recently, ARNT has been reported to a play role in pancreatic-islet function in type 2 diabetes. However, the role of ARNT in kidney cancer h...

journal_title：Oncology letters

authors： Zhao Y,Han F,Zhang X,Zhou C,Huang D

更新日期：2020-10-01 00:00:00

abstract：:AR-42 is a member of a novelly discovered class of phenylbutyrate-derived histone deacetylase inhibitors, and has a number of antitumor effects in a variety of tumor types; however, the role of AR-42 and its possible mechanisms have not been reported in the treatment of breast cancer. The aim of the present study was ...

journal_title：Oncology letters

authors： Zhou R,Wu J,Tang X,Wei X,Ju C,Zhang F,Sun J,Shuai D,Zhang Z,Liu Q,Lv XB

更新日期：2018-08-01 00:00:00

abstract：:The expression levels of cyclooxygenase (COX)-2 and the prostaglandin E2 (PGE2) content have been associated with poor prognosis in patients with colorectal cancer (CRC). There is a strong correlation between COX-2 expression and PGE2 production in tissues from CRC patients, suggesting an important role for COX-2 on t...

journal_title：Oncology letters

authors： Cervantes-Madrid DL,Nagi S,Asting Gustafsson A

更新日期：2017-03-01 00:00:00

abstract：:Increasing number of microRNAs (miRNAs) have been reported to play an important role in the development and progression of non-small cell lung cancer (NSCLC). In particular, microRNA-497-5p (miR-497-5p) has been proposed as a tumor suppressor miRNA in human cancers. However, the role of miR-497-5p and its potential mo...

journal_title：Oncology letters

authors： Huang X,Wang L,Liu W,Li F

更新日期：2019-03-01 00:00:00

abstract：:Hypoxia is a critical aspect of tumor biology and has been associated with poor prognosis and resistance to traditional therapy. In the present study, differentially expressed genes and microRNAs (miRNAs/miRs) were screened for in the hepatocellular carcinoma (HCC) cell line Huh7 under hypoxic conditions. On the basis...

journal_title：Oncology letters

authors： Hu B,Tang WG,Fan J,Xu Y,Sun HX

更新日期：2018-01-01 00:00:00

abstract：:Glucagonoma is an extremely rare pancreatic α-islet cell tumor and is often accompanied by certain clinical symptoms including necrotizing migratory erythema (NME), diabetes, weight loss and anemia. The objectives of the current review were to discern the clinical features, diagnosis, treatment and prognosis of glucag...

journal_title：Oncology letters

authors： Song X,Zheng S,Yang G,Xiong G,Cao Z,Feng M,Zhang T,Zhao Y

更新日期：2018-03-01 00:00:00

abstract：:Rare types of cancer are often not effectively treated by approaches such as chemotherapy and radio-therapy, although their side-effects persist. Immunotherapy has been gaining attention worldwide with growing examples of its anticancer activity demonstrated in vivo. This case report describes a 35-year-old male who s...

journal_title：Oncology letters

authors： Ratnavelu K,Subramani B,Pullai CR,Krishnan K,Sugadan SD,Rao MS,Veerakumarasivam A,Deng X,Hiroshi T

更新日期：2013-05-01 00:00:00

abstract：:Leptomeningeal metastasis (LM) is an uncommon presentation of relapse in breast cancer, which is associated with poor clinical outcomes and poor prognosis. Notably, LM most commonly occurs in breast cancer. The aim of the present review was to investigate the occurrence of LM as the primary presentation of relapse fol...

journal_title：Oncology letters

authors： Sacco K,Muhammad A,Saleem W,Alshaker H,Monzon L,Islam MR,Pchejetski D

更新日期：2016-08-01 00:00:00

abstract：:Docetaxel is a well-known causative agent of nail alterations. The aim of this study was to reveal the impact of nail alterations associated with low-dose metronomic (LDM) docetaxel chemotherapy on the survival of non-small cell lung cancer (NSCLC) patients. Clinical information, survival data and nail alterations in ...

journal_title：Oncology letters

authors： Kibata K,Tamaki T,Inagaki N,Ogata M,Shimizu T,Nomura S

更新日期：2013-04-01 00:00:00