Abstract:
:Solitary fibrous tumors (SFTs) are uncommon, with the pleura as a site of predilection. Central nervous system SFTs, particularly intracranial SFTs, are extremely rare. The lesions are generally benign and localized, and surgery is the main therapeutic solution. The current study reports the cases of a patient who presented with right haunch pain, right leg weakness and paresthesias for several months, and a patient with a history of unexpected loss of consciousness. Magnetic resonance imaging revealed the presence of lesions, with a spindle cell morphology evident on pathological examination. The immunohistochemical examination demonstrated a strong immunoreaction for cluster of differentiation 34, which supported the diagnosis of an SFT. Following a near-total resection, the patients had a good neural prognosis. The present study also provides a literature review, discussing the imageological and pathological characteristics of SFT, and the diagnostic methods that aid in distinguishing the entity from other spindle-cell central nervous system tumors.
journal_name
Oncol Lettjournal_title
Oncology lettersauthors
Wang ZY,Qiu K,Ma YH,Wang XT,Bao JJ,Zhang ZF,Liu XZdoi
10.3892/ol.2015.3985subject
Has Abstractpub_date
2016-02-01 00:00:00pages
1057-1060issue
2eissn
1792-1074issn
1792-1082pii
OL-0-0-3985journal_volume
11pub_type
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