Overexpression of miR-301a-3p promotes colorectal cancer cell proliferation and metastasis by targeting deleted in liver cancer-1 and runt-related transcription factor 3.

abstract：:The physiologically active form of vitamin D3, 1,25-dihydroxyvitamin D3 (1,25(OH)2D3) has influence over osteoclastogenesis and myelopoiesis, but the regulational mechanism is not well-defined. In this report, formation of osteoclast-like (OCL) cells from primitive myeloid colony-forming cells (PM-CFC) as mediated by ...

journal_title：Journal of cellular biochemistry

authors： Qi DY,Perkins SL,Kling SJ,Russell RG

更新日期：1999-03-01 00:00:00

abstract：BACKGROUND:Inflammatory bowel disease (IBD) is one of the most important immune-mediated disorders of the gastrointestinal tract. Besides, IBD is associated with numerous extraintestinal complications such as venous thromboembolism (VTE), an important risk factor for vascular complications, which results in the increas...

journal_title：Journal of cellular biochemistry

authors： Asadzadeh-Aghdaei H,Mashayekhi K,Koushki K,Azimzadeh P,Rostami-Nejad M,Amani D,Chaleshi V,Haftcheshmeh SM,Sahebkar A,Zali MR

更新日期：2019-09-01 00:00:00

abstract：:Cancer prevalence is critically increasing worldwide; accordingly, improved prediction and therapeutic tools are necessary. Interleukin (IL)-21 is a potent antitumor cytokine, and the relationship between its gene variations and cancer risk is well established. Nevertheless, so far no study has investigated its role i...

journal_title：Journal of cellular biochemistry

authors： Bakr NM,Awad A,Moustafa EA,El-Gebaly AM

更新日期：2019-10-01 00:00:00

abstract：:We have analyzed the distribution of type II collagen N- and C-propeptides in the cell layers and culture medium of bovine articular chondrocyte pellet cultures. Two splice variants of the type II collagen N-propeptide were detected by immunoblotting and immunoassay, using a new anti-peptide antibody, while the C-prop...

journal_title：Journal of cellular biochemistry

authors： Rebuck N,Croucher LJ,Hollander AP

更新日期：1999-10-01 00:00:00

abstract：OBJECTIVE:Hepatocellular carcinoma (HCC) has a high morbidity and mortality around the world, yet the effective therapeutic option for HCC is still limited. NPAC, also known as glyoxylate reductase 1 homolog, is a new nuclear protein recently implicated in tumor biology. However, the role of NPAC in HCC remains unclear...

journal_title：Journal of cellular biochemistry

authors： Zhang J,Sun N,Guo W,Wu X,Yang X,Jin H,Zhang Y,Wu X,Zhang F,Hu L,Hu H,Gao Y

更新日期：2018-11-26 00:00:00

abstract：:The epidermal growth factor receptor (EGFR) and signal transducers and activators of transcription (STATs) are commonly expressed and activated in many malignancies. EGFR is an upstream activator of several pathways involved in tumor progression, and STATs activate selected genes involved in oncogenesis. There are sev...

journal_title：Journal of cellular biochemistry

authors： Quesnelle KM,Boehm AL,Grandis JR

更新日期：2007-10-01 00:00:00

abstract：:Breast cancer is a highly aggressive disease contributing to high mortality rate among females across the globe owing to wide geographical variations, change in lifestyle along with rapid tumor growth, drug resistance, and high metastasis rate. To understand the molecular and genetic basis of breast cancer progression...

journal_title：Journal of cellular biochemistry

authors： Nazir SU,Kumar R,Dil-Afroze,Rasool I,Bondhopadhyay B,Singh A,Tripathi R,Singh N,Khan A,Tanwar P,Agrawal U,Mehrotra R,Hussain S

更新日期：2019-09-01 00:00:00

abstract：:Proliferation of endothelial cells is regulated by angiogenic and antiangiogenic factors whose actions are mediated by complex interactions of multiple signaling pathways. Both vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) stimulate cell proliferation and activate the mitogen-acti...

journal_title：Journal of cellular biochemistry

authors： D'Angelo G,Lee H,Weiner RI

更新日期：1997-12-01 00:00:00

abstract：:The objective of this study was to test the hypothesis that extracellular matrix (ECM) would alter the endoplasmic reticulum (ER) stress response of chondrocytes. Chondrocytes were isolated from calf knees and maintained in monolayer culture or suspended in collagen I to form spot cultures (SCs). Our laboratory has sh...

journal_title：Journal of cellular biochemistry

authors： Nugent AE,McBurney DL,Horton WE Jr

更新日期：2011-04-01 00:00:00

abstract：:We have previously characterized the expression of the alpha nu beta 5 and alpha nu beta 6 integrins as major receptors for the human colonic adenocarcinoma cell line (HT29-D4), on vitronectin and fibronectin, respectively [Lehmann et al. (1994): Cancer Res 54:2102-2107]. In the present work we investigated the glycos...

journal_title：Journal of cellular biochemistry

authors： Lehmann M,El Battari A,Abadie B,Martin JM,Marvaldi J

更新日期：1996-05-01 00:00:00

abstract：:The objective of this study was to evaluate the genotoxic and mutagenic effects of the toxins present in Lachesis muta muta's venom on human peripheral blood leukocytes and the protective potential of ascorbic acid on DNA fragmentation. The venom of L. muta muta was incubated in different concentrations (1, 2.5, 5, 7....

journal_title：Journal of cellular biochemistry

authors： Cardoso Trento MV,de Faria Eleutério MW,Silva Abreu T,Andrade Machado GH,Cesar PHS,Assaid Simão A,Marcussi S

更新日期：2019-03-01 00:00:00

abstract：:Fibroblast growth factor 2 (FGF-2) has been found to play an anti-anabolic and/or a catabolic role in adult human articular cartilage via regulation of multiple signaling pathways. Upon FGF-2 stimulation, a molecular crosstalk between the mitogen activated protein kinase (MAPK) and protein kinase C δ (PKCδ) pathways a...

journal_title：Journal of cellular biochemistry

authors： Yan D,Chen D,Im HJ

更新日期：2012-09-01 00:00:00

abstract：:Adipose-derived mesenchymal stromal cells (ADSCs) exhibited high potential in tissue repair and regeneration, and it has been proved that ADSCs could protect brain cells from apoptosis and maintaining blood-brain barrier stability after cerebral vascular disease. In this study, we evaluated the therapeutic potential a...

journal_title：Journal of cellular biochemistry

authors： Zhang Y,Deng H,Hu Y,Pan C,Wu G,Li Q,Tang Z

更新日期：2019-09-01 00:00:00

abstract：:In this study, we purpose to investigate a novel five-gene signature for predicting the prognosis of patients with laryngeal cancer. The laryngeal cancer datasets were obtained from The Cancer Genome Atlas (TCGA). Both univariate and multivariate Cox regression analysis was applied to screening for prognostic differen...

journal_title：Journal of cellular biochemistry

authors： Zhang G,Fan E,Yue G,Zhong Q,Shuai Y,Wu M,Feng G,Chen Q,Gou X

更新日期：2019-10-31 00:00:00

abstract：:Bone formation in the embryo, and during adult fracture repair and remodeling, involves the progeny of a small number of cells called mesenchymal stem cells (MSCs). These cells continuously replicate themselves, while a portion become committed to mesenchymal cell lineages such as bone, cartilage, tendon, ligament, an...

journal_title：Journal of cellular biochemistry

authors： Bruder SP,Fink DJ,Caplan AI

更新日期：1994-11-01 00:00:00

abstract：:Resistance to therapies, recurrence, and metastasis remain challenging issues for breast cancer patients, particularly for triple-negative and breast cancer stem cells. The activation of the epithelial-to-mesenchymal transition (EMT) plays an indispensable role in the poor prognosis of those types. The accumulating pr...

journal_title：Journal of cellular biochemistry

authors： Koohestanimobarhan S,Salami S,Imeni V,Mohammadi Z,Bayat O

更新日期：2018-09-06 00:00:00

abstract：:Hypoxia promotes angiogenesis by modulating the transcriptional regulator hypoxia-inducible factor 1alpha (HIF-1alpha). HIF-1alpha is a master regulator of the hypoxic response, and its proangiogenic activities include, but are not limited to, regulation of vascular endothelial growth factor (VEGF). The remodeling of ...

journal_title：Journal of cellular biochemistry

authors： Corley KM,Taylor CJ,Lilly B

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:Gram-negative bacterium, Helicobacter pylori is notorious for various pathologies like peptic ulcers, gastritis, functional dyspepsia, and various cancers. METHODS:Systemic effects of its toxins have led scientists' attention toward the extragastric pathologies associated with it. To date, it has been shown...

journal_title：Journal of cellular biochemistry

authors： Zendehdel A,Roham M

更新日期：2019-08-01 00:00:00

abstract：:Fourteen stable subclones derived from the murine chondrogenic cell line MC615 were established and characterised regarding their differentiation stages and responsivity to BMP2. Based on their gene expression profiles which revealed remarkable variances in Col2a1 and Col10a1 expression, subclones could be grouped int...

journal_title：Journal of cellular biochemistry

authors： Surmann-Schmitt C,Widmann N,Mallein-Gerin F,von der Mark K,Stock M

更新日期：2009-10-15 00:00:00

abstract：:Calcium-dependent cell adhesion molecules (CAMs) mediate intercellular adhesion in epithelial cells and in preimplantation mammalian embryos. One of these molecules, cell-CAM 120/80, is found on cells as a 120-kd membrane glycoprotein and as a soluble 80-kd species in conditioned culture medium [Damsky et al: Cell 34:...

journal_title：Journal of cellular biochemistry

authors： Wheelock MJ,Buck CA,Bechtol KB,Damsky CH

更新日期：1987-07-01 00:00:00

abstract：:The mouse macrophage Fc gamma 2b/gamma 1R has previously been purified with the aid of the monoclonal antibody 2.4G2. That this Fc gamma R functions as a ligand-dependent ion channel is supported by the following evidence. Employing [3H]tetraphenylphosphonium ([3H]Ph4P+) as a probe for membrane potential changes in in...

journal_title：Journal of cellular biochemistry

authors： Young JD,Unkeless JC,Cohn ZA

更新日期：1985-01-01 00:00:00

abstract：:Ligamentum flavum (LF)-derived mesenchymal stem cells (MSCs) have been implicated in the pathogenesis of calcification of the ligamentum flavum (CLF) leading to the increased presence of chondrocyte-like cells and calcium deposition in CLF; however, the mechanisms of LF-MSCs in differentiation are not defined. In this...

journal_title：Journal of cellular biochemistry

authors： Zhang Q,Wang S,Sheng Y,Zhao S,Jiang Y,Zhou D,Yang H

更新日期：2019-03-01 00:00:00

abstract：:Epidermal Differentiation Complex (EDC) is a gene cluster on human chromosome 1 q21, which comprises genes encoding four protein families: S100, S100 fused (SFTP), small proline-rich region (SPRR) and late cornified envelope (LCE) proteins. Contrary to the latter three families, which group proteins important for skin...

journal_title：Journal of cellular biochemistry

authors： Sobiak B,Graczyk-Jarzynka A,Leśniak W

更新日期：2016-05-01 00:00:00

abstract：:Ultraprofound hypothermia (< 5 degrees C) induces changes to cell membranes such as liquid-to-gel lipid transitions and oxidative stress that have a negative effect on membrane function and cell survival. We hypothesized that fatty acid substitution of endothelial cell lipids and alterations in their unsaturation woul...

journal_title：Journal of cellular biochemistry

authors： Zieger MA,Gupta MP,Siddiqui RA

更新日期：2006-10-15 00:00:00

abstract：:Although, the precise host defence mechanism(s) is not completely understood, T cell-mediated immune responses is believed to play a pivotal role in controlling parasite infection. Here we target the stage dependent over expressed gene. Here, the consensus based computational approach was adopted for the screening of ...

journal_title：Journal of cellular biochemistry

authors： Dikhit MR,Vijayamahantesh.,Kumar A,Amit A,Dehury B,Nathsharma YP,Ansari MY,Ali V,Topno RK,Das V,Pandey K,Sahoo GC,Bimal S,Das P

更新日期：2018-01-01 00:00:00

abstract：:The role of regucalcin in the regulation of osteoblastic cell function was investigated. Osteoblastic MC3T3-E1 cells with subconfluent monolayers were cultured in a medium containing regucalcin (10(-10)-10(-8) M) without fetal bovine serum (FBS). The proliferation of osteoblastic cells was not significantly altered in...

journal_title：Journal of cellular biochemistry

authors： Yamaguchi M,Kobayashi M,Uchiyama S

更新日期：2005-10-15 00:00:00

abstract：:To determine the role of thrombin high-affinity receptor occupancy and enzymic activity in thrombin initiation of cell proliferation, we have utilized thrombin derivatives which separate these functions. We previously showed that enzymically active gamma-thrombin stimulates ion fluxes without binding to high-affinity ...

journal_title：Journal of cellular biochemistry

authors： Carney DH,Stiernberg J,Fenton JW 2nd

更新日期：1984-01-01 00:00:00

abstract：:Emerging evidence indicates that activation of Wnt/β-catenin signaling at the cell surface results in inhibition of glycogen synthase kinase 3β (GSK3β), leading to activation of mTORC1 signaling in cancer cells. The low density lipoprotein receptor-related protein-6 (LRP6) is an essential Wnt co-receptor for Wnt/β-cat...

journal_title：Journal of cellular biochemistry

authors： Lu W,Li Y

更新日期：2014-10-01 00:00:00

abstract：:Interleukin-1β (IL-1β) assumes a centric role in the regulation of immune and inflammatory responses and thus has been recognized in immune mediated diseases like type 2 diabetes mellitus (T2DM). We aimed to investigate expressed level of IL-1β and its relation with IL-1β -511T>C polymorphism in T2DM patients. This st...

journal_title：Journal of cellular biochemistry

authors： Tayel SI,Fouda EAM,Elshayeb EI,Eldakamawy ARA,El-Kousy SM

更新日期：2018-07-01 00:00:00

abstract：:Long noncoding RNAs (lncRNAs) serve as competitive endogenous RNAs (ceRNAs) that play significant regulatory roles in the pathogenesis of tumors. However, the role of lncRNAs, especially the lncRNA-related ceRNA regulatory network, in glioblastoma (GBM) has not been fully elucidated. The goal of the current study was ...

journal_title：Journal of cellular biochemistry

authors： Liu Z,Wang X,Yang G,Zhong C,Zhang R,Ye J,Zhong Y,Hu J,Ozal B,Zhao S

更新日期：2020-07-01 00:00:00