Functional ion channel formation by mouse macrophage IgG Fc receptor triggered by specific ligands.

abstract：:Myelin basic protein (MBP) is a major component of the myelin sheath whose production is developmentally controlled during myelinogenesis. Earlier studies have indicated that programmed expression of the MBP gene is regulated at the level of transcription. Evidently, the MB1 regulatory motif located between nucleotide...

journal_title：Journal of cellular biochemistry

authors： Muralidharan V,Tretiakova A,Steplewski A,Haas S,Amini S,Johnson E,Khalili K

更新日期：1997-09-15 00:00:00

abstract：:To obtain sufficient numbers of cells for tissue engineering applications, human bone marrow-derived mesenchymal stem cells (hBM-MSC) are commonly cultured as monolayers in incubators containing room air. In this study, we investigated whether three-dimensional (3D) culture conditions and incubator gas concentrations ...

journal_title：Journal of cellular biochemistry

authors： Karlsen TA,Mirtaheri P,Shahdadfar A,Fløisand Y,Brinchmann JE

更新日期：2011-02-01 00:00:00

abstract：:Gastric cancer (GC) is the fifth most frequent cancer and the third-leading cause of cancer-related death worldwide. It is a highly heterogeneous disease regarding the morphological and molecular viewpoints. Since it is curable in primary stages, early detection could improve the survival rate. Long noncoding RNAs con...

journal_title：Journal of cellular biochemistry

authors： Kangarlouei R,Irani S,Noormohammadi Z,Memari F,Mirfakhraie R

更新日期：2019-08-01 00:00:00

abstract：:Cancer stem cells (CSCs) are tumoral cells which have stem features such as self-renewal, high migration capacity, drug resistance, high proliferation abilities. In the last 10 years the pathological meaning and the existence of CSCs have been matter of discussion and a large number of articles have been published abo...

journal_title：Journal of cellular biochemistry

authors： Graziano A,d'Aquino R,Tirino V,Desiderio V,Rossi A,Pirozzi G

更新日期：2008-02-01 00:00:00

abstract：:To study hematopoietic differentiation a variety of in vitro systems have been established using hematopoietic precursors derived from various explanted adult and fetal tissues. In this prospective we describe and discuss the potential of a novel system for studying the earliest stages of hematopoietic development. In...

journal_title：Journal of cellular biochemistry

authors： Snodgrass HR,Schmitt RM,Bruyns E

更新日期：1992-07-01 00:00:00

abstract：:The presented results show for the first time that the neurogenic transdifferentiation of hUC-MSCs considerably changes the elements of purinergic signaling profile. Although, it has been demonstrated in the literature that extracellular nucleotides and nucleosides determine the fate of mesenchymal and neural stem cel...

journal_title：Journal of cellular biochemistry

authors： Czarnecka J,Porowińska D,Bajek A,Hołysz M,Roszek K

更新日期：2017-03-01 00:00:00

abstract：:Tetralogy of Fallot (TOF) is the most common form of cyanotic congenital heart disease. To identify endogenous peptides possibly involved in the progression of TOF, we performed comparative peptidomic profiling of maternal serum between normal fetuses and fetuses suffering from TOF. A total of 278 differentially expre...

journal_title：Journal of cellular biochemistry

authors： Zhuang B,Hu Y,Fan X,Li M,Zhu J,Liu H,Cao L,Liang D,Zhang J,Yu Z,Han S

更新日期：2018-01-01 00:00:00

abstract：:Thymosin β-4 (Tβ4) is a ubiquitous protein, which has been suggested to regulate multiple cell signal pathways and a variety of cellular functions. However, the role Tβ4 plays in the cardiac microvascular endothelial cells (CMECs) under myocardial ischemia/reperfusion injury is currently unknown. Here we investigated ...

journal_title：Journal of cellular biochemistry

authors： Li Y,Zhu X,Liu X,Du A,Yu B

更新日期：2019-11-01 00:00:00

abstract：:During embryonic development, the hematopoietic system is the first to generate terminally differentiated, functional cell types. The urgent necessity for the early formation of blood and blood vessels during embryogenesis means that the induction, expansion, and maturation of these systems must be rapidly and precise...

journal_title：Journal of cellular biochemistry

authors： Snyder A,Fraser ST,Baron MH

更新日期：2004-10-01 00:00:00

abstract：:Osteoporosis (OP) is a multifactorial and common bone disease worldwide. The clinical diagnosis and treatment of osteoporosis has limitations since changes in bone density occur slightly. Thus, it is critically needed to look for new biomarkers to identify and cure osteoporosis. CircRNAs are important molecular regula...

journal_title：Journal of cellular biochemistry

authors： Huang Y,Xie J,Li E

更新日期：2019-09-01 00:00:00

abstract：:The present study aimed to determine the roles of miRNA-543 in osteoporosis in rats induced by ovariectomy. The osteoporosis rat model was established by ovariectomy induction. MiRNA-543 expression in osteoblasts was measured by quantitative real-time polymerase chain reaction. The cell proliferation and apoptosis wer...

journal_title：Journal of cellular biochemistry

authors： Li X,Ning L,Zhao X,Wan S

更新日期：2018-12-02 00:00:00

abstract：:Genistein, a natural isoflavone phytoestrogen present in soybeans, caused a dose-dependent growth inhibition of the two hormone-sensitive cell lines T47D and ZR75.1 and of the two hormone-independent cell lines MDAMB-231 and BT20. Flow cytometric analysis of cells treated for 4 days with 15 and 30 microM genistein sho...

journal_title：Journal of cellular biochemistry

authors： Cappelletti V,Fioravanti L,Miodini P,Di Fronzo G

更新日期：2000-09-14 00:00:00

abstract：:Individual protein kinase C (PKC) isoforms fulfill distinct roles in the regulation of the commitment to differentiation, cell cycle arrest, and apoptosis in both monocytes and T-cells. The human monocyte like cell line U937 and T-cells were exposed to microgravity, during spaceflight and the translocation (a critical...

journal_title：Journal of cellular biochemistry

authors： Hatton JP,Gaubert F,Cazenave JP,Schmitt D

更新日期：2002-01-01 00:00:00

abstract：:Platelets are critical regulators of liver regeneration, but the mechanisms are still not fully understood. Platelets have been shown to contain a wide variety of microRNAs (miRNAs) and play an important role in many diseases. However, the mechanism that how the platelet microparticles (PMPs)-derived miRNA regulate th...

journal_title：Journal of cellular biochemistry

authors： Xu Y,Li W,Liang G,Peng J,Xu X

更新日期：2020-07-21 00:00:00

abstract：:Pancreatic ductal adenocarcinoma (PDAC) is an incidence rate nearly equal to its mortality rate. The poor prognosis of the disease can be explained by the absence of effective biomarkers for screening and early detection, together with the aggressive behavior and resistance to the currently available chemotherapy. The...

journal_title：Journal of cellular biochemistry

authors： Barati Bagherabad M,Afzaljavan F,ShahidSales S,Hassanian SM,Avan A

更新日期：2019-03-01 00:00:00

abstract：:Peroxiredoxins are ubiquitous proteins that recently attracted major interests in view of the strict correlation observed in several cell lines and/or tissues between different levels of their expression and the increased capacity of cells to survive in different pathophysiological conditions. They are recently consid...

journal_title：Journal of cellular biochemistry

authors： Cimini A,Gentile R,Angelucci F,Benedetti E,Pitari G,Giordano A,Ippoliti R

更新日期：2013-03-01 00:00:00

abstract：:E-peptide of the pro-Insulin-like growth factor-I (pro-IGF-I) is produced from pre-pro-IGF-I by proteolytic cleavage in the post-translational processing. Previous in vitro studies conducted in our laboratory showed that Ea4-peptide of rainbow trout (rt) pro-IGF-I or Eb-peptide of human (h) pro-IGF-I exhibited activit...

journal_title：Journal of cellular biochemistry

authors： Chen MJ,Chiou PP,Lin P,Lin CM,Siri S,Peck K,Chen TT

更新日期：2007-08-01 00:00:00

abstract：:Oxidative stress is an important underlying cause of many disease processes and may arise due to either increasing free radical generation or decreasing antioxidant defense systems. MicroRNAs (miRs) are 22-nucleotide non-coding RNAs that may regulate many intracellular processes; and, more recently, they have been imp...

journal_title：Journal of cellular biochemistry

authors： Yaribeygi H,Atkin SL,Sahebkar A

更新日期：2018-08-30 00:00:00

abstract：:LipN (Rv2970c) belongs to the Lip family of M. tuberculosis H37Rv and is homologous to the human Hormone Sensitive Lipase. The enzyme demonstrated preference for short carbon chain substrates with optimal activity at 45°C/pH 8.0 and stability between pH 6.0-9.0. The specific activity of the enzyme was 217 U/mg protein...

journal_title：Journal of cellular biochemistry

authors： Jadeja D,Dogra N,Arya S,Singh G,Singh G,Kaur J

更新日期：2016-02-01 00:00:00

abstract：:HOXB13 exerts a close relation in several human cancers. This study explored the role of HOXB13 in glioblastoma (GBM), a brain tissue with the highest aggressive rate and mortality in adults. Through microarray and immunohistochemistry analyses, HOXB13 was highly expressed in GBM tissues. Furthermore, we showed that h...

journal_title：Journal of cellular biochemistry

authors： Wang X,Sun Y,Xu T,Qian K,Huang B,Zhang K,Song Z,Qian T,Shi J,Li L

更新日期：2019-09-01 00:00:00

abstract：:This study performed the first microarray analysis of long-noncoding RNA (lncRNA) and mRNA expression profiles in human steroid-induced avascular necrosis of the femoral head (SAVNFH). Expression levels of lncRNAs and mRNAs in three human SAVNFH samples and three human femoral head fracture samples (controls) were det...

journal_title：Journal of cellular biochemistry

authors： Luo H,Lan W,Li Y,Lian X,Zhang N,Lin X,Chen P

更新日期：2019-09-01 00:00:00

abstract：:New perinatal care technologies have improved the survival rate of preterm neonates, but the prevalence of bronchopulmonary dysplasia (BPD), one of the most intractable problems in neonatal intensive care unit (NICU), remains unchanged. In present study, high-throughput sequencing (HTS) was performed to detect the exp...

journal_title：Journal of cellular biochemistry

authors： Wang J,Yin J,Wang X,Liu H,Hu Y,Yan X,Zhuang B,Yu Z,Han S

更新日期：2019-06-01 00:00:00

abstract：:Intact embryonic chick neural retina cells have at their surface an N-acetylgalactosaminyltransferase which catalyzes the incorporation of N-acetylgalactosamine from UDP-N-acetylgalactosamine into endogenous macromolecular acceptors. The enzyme along with its endogenous acceptors can be isolated as a particulate compl...

journal_title：Journal of cellular biochemistry

authors： Balsamo J,Pratt RS,Emmerling MR,Grunwald GB,Lilien J

更新日期：1986-01-01 00:00:00

abstract：:SCN- binds to the charged amino group of lysines, inducing local changes in the electrostatic free energy of histones. We exploited this property to selectively perturb the histone-DNA interactions involved in the stabilization of eu and heterochromatin. Differential scanning calorimetry (DSC) was used as leading tech...

journal_title：Journal of cellular biochemistry

authors： Patrone E,Coradeghini R,Barboro P,D'Arrigo C,Mormino M,Parodi S,Balbi C

更新日期：2006-03-01 00:00:00

abstract：:Amyloid-β protein (Aβ) is the main component of senile plaques in the brains of Alzheimer disease (AD) patients. Aβ is proteolytically derived from amyloid-β precursor protein by β- and γ-secretases. Secreted Aβ is then eliminated from the central nervous system by multiple clearance mechanisms, including phagocytosis...

journal_title：Journal of cellular biochemistry

authors： Kikuchi K,Kidana K,Tatebe T,Tomita T

更新日期：2017-12-01 00:00:00

abstract：:We have used a retroviral vector (RCAS) to overexpress wild-type chicken c-Jun or a deletion mutant of chicken c-Jun (Jun delta 7) lacking the DNA binding region to investigate the possible role of c-Jun in lens epithelial cell proliferation and differentiation. Both constructs were efficiently expressed in primary cu...

journal_title：Journal of cellular biochemistry

authors： Rinaudo JA,Vacchiano E,Zelenka PS

更新日期：1995-06-01 00:00:00

abstract：:Muscular dystrophies are characterized by continuous cycles of degeneration and regeneration that result in extensive fibrosis and a progressive diminution of muscle mass. Cell surface heparan sulfate proteoglycans are found almost ubiquitously on the surface and in the extracellular matrix (ECM) of mammalian cells. T...

journal_title：Journal of cellular biochemistry

authors： Alvarez K,Fadic R,Brandan E

更新日期：2002-01-01 00:00:00

abstract：:Fibrosis, the deadly pathological manifestation of an abnormal tissue remodeling in any organ due to excessive collagen deposition, is associated with a wide variety of organ failure-related human diseases. Chronic stress or repeated injury in a particular organ induces abnormal molecular signals that lead to super-ac...

journal_title：Journal of cellular biochemistry

authors： Ghosh AK

更新日期：2014-09-01 00:00:00

abstract：:Hsp47, Grp78, and Grp94 have been implicated with procollagen maturation events. In particular, Hsp47 has been shown to nascent procollagen alpha 1(I) chains in the course of synthesis and/or translocation into the endoplasmic reticulum (ER). Although, Hsp47 binding to gelatin and collagen has previously been suggeste...

journal_title：Journal of cellular biochemistry

authors： Ferreira LR,Norris K,Smith T,Hebert C,Sauk JJ

更新日期：1994-12-01 00:00:00

abstract：:The conditions favoring expression of a reporter gene microinjected into a male pronucleus of naturally ovulated and fertilized rabbit eggs have been studied. Injection of the reporter gene during S phase of the cell-cycle allows the highest level of expression of the gene. Incorporation of DNA loop anchorage regions ...

journal_title：Journal of cellular biochemistry

authors： Goldman IL,Razin SV,Kadulin SG,Vassetzky YS

更新日期：2004-08-15 00:00:00