Adipose-derived mesenchymal stem cells stereotactic transplantation alleviate brain edema from intracerebral hemorrhage.

abstract：:Preeclampsia is a pathologic complication of pregnancy, associated with increased apoptosis in the cytotrophoblasts as the main cause of this disorder. Caspase-3 is a key apoptosis-related enzyme that both mitochondrial and death receptor apoptotic pathways can activate. In this study, we aimed to investigate the effe...

journal_title：Journal of cellular biochemistry

authors： Teimoori B,Yazdi A,Rezaei M,Mohammadpour-Gharehbagh A,Jahantigh D,Salimi S

更新日期：2018-08-01 00:00:00

abstract：:Endometrial cancer is one of the most common gynecological malignant tumors. The roles of competing endogenous RNAs (ceRNAs) in this disease, however, remain unclear. In this study, we constructed a ceRNA network to reveal the core ceRNAs in endometrial cancer. Differentially expressed genes were summarized from The C...

journal_title：Journal of cellular biochemistry

authors： Wang Y,Huang T,Sun X,Wang Y

更新日期：2019-11-01 00:00:00

abstract：:Photodynamic therapy (PDT) employing methyl δ-aminolevulinic acid (Me-ALA), as a precursor of the photosensitizer protoporphyrin IX (PpIX), is used for the treatment of non melanoma cutaneous cancer (NMCC). However, one of the problems of PDT is the apparition of resistant cell populations. The aim of this study was t...

journal_title：Journal of cellular biochemistry

authors： Milla LN,Cogno IS,Rodríguez ME,Sanz-Rodríguez F,Zamarrón A,Gilaberte Y,Carrasco E,Rivarola VA,Juarranz A

更新日期：2011-09-01 00:00:00

abstract：:Chronic lymphocytic leukemia (CLL), a severe problem all over the world and represents around 25% of all total leukemia cases, is generating the need for novel targets against CLL. Wnt signaling cascade regulates cell proliferation, differentiation, and cell death processes. Thus, any alteration of the Wnt signaling p...

journal_title：Journal of cellular biochemistry

authors： Bhattacharya M,Sharma AR,Sharma G,Patra BC,Lee SS,Chakraborty C

更新日期：2020-11-01 00:00:00

abstract：:Selenoprotein P (SePP) is involved in the protection against diseases. The present study is the first investigation of the effect of selenium supplementation on plasma selenium and expression of SEPP1 in mRNA and protein levels based on metabolic syndrome (MetS), in individuals suffering from coronary artery diseases....

journal_title：Journal of cellular biochemistry

authors： Gharipour M,Ouguerram K,Nazih EH,Salehi M,Behmanesh M,Roohafza H,Hosseini SM,Nezafati P,Dianatkhah M,Gharipour A,Haghjoo S,Sarrafzadegan N,Sadeghi M

更新日期：2018-11-01 00:00:00

abstract：:Countercurrent centrifugal elutriation was used to separate growth plate chondrocytes from porcine basing on their differences in sizes and densities. Eighteen fractions of cells with different sizes and densities were obtained. The mean cellular volumes increased progressively in each of successive fractions, and tha...

journal_title：Journal of cellular biochemistry

authors： Lee KM,Fung KP,Leung PC,Leung KS

更新日期：1996-03-15 00:00:00

abstract：:Copy number variation (CNV) and abnormal expression of microRNAs (miRNAs) always lead to deregulation of genes in cancer, including gastric cancer (GC). However, little is known about how CNVs affect the expression of miRNAs. By integrating CNV and miRNA profiles in the same samples, we identified eight miRNAs (miR-12...

journal_title：Journal of cellular biochemistry

authors： An J,Pan Y,Yan Z,Li W,Cui J,Yuan J,Tian L,Xing R,Lu Y

更新日期：2013-09-01 00:00:00

abstract：:Emerging evidence indicates that activation of Wnt/β-catenin signaling at the cell surface results in inhibition of glycogen synthase kinase 3β (GSK3β), leading to activation of mTORC1 signaling in cancer cells. The low density lipoprotein receptor-related protein-6 (LRP6) is an essential Wnt co-receptor for Wnt/β-cat...

journal_title：Journal of cellular biochemistry

authors： Lu W,Li Y

更新日期：2014-10-01 00:00:00

abstract：:Selected clones of Syrian hamster DDT1-MF2 cells are responsive to testosterone for growth. Heparin binding growth factor 1 (HBGF-1) or acidic fibroblast growth factor (aFGF) can replace testosterone (T) in the stimulation of growth in these cells. This phenomena is correlated with testosterone's ability to elevate aF...

journal_title：Journal of cellular biochemistry

authors： Hall JA,Harris MA,Intres R,Harris SE

更新日期：1993-01-01 00:00:00

abstract：:Cancer is characterized by uncontrolled cell division resulting from multiple mutagenic events. Cancer chemoprevention strategies aim to inhibit or reverse these events using natural or synthetic pharmacologic agents. Ideally, this restores normal growth control mechanisms. Diverse classes of compounds have been ident...

journal_title：Journal of cellular biochemistry

authors： Freemantle SJ,Liu X,Feng Q,Galimberti F,Blumen S,Sekula D,Kitareewan S,Dragnev KH,Dmitrovsky E

更新日期：2007-11-01 00:00:00

abstract：:Telomeres are TTAGGG repetitive motifs found at the ends of vertebrate chromosomes. In humans, telomeres are protected by shelterin, a complex of six proteins (de Lange [2005] Genes Dev. 19: 2100-2110). Since (Müller [1938] Collecting Net. 13: 181-198; McClintock [1941] Genetics 26: 234-282), their function in maintai...

journal_title：Journal of cellular biochemistry

authors： Mai S,Garini Y

更新日期：2006-04-01 00:00:00

abstract：:Due to the increasing incidence and mortality, the early diagnosis, specific targeted therapies, and prognosis for colorectal cancer (CRC) attract more and more attention. Wild-type p53-induced phosphatase 1 (Wip1) and karyopherin α2 (KPNA2) have been regarded as oncogenes in many cancers, including CRC. Wip1 dephosph...

journal_title：Journal of cellular biochemistry

authors： Wang P,Zhao Y,Liu K,Liu X,Liang J,Zhou H,Wang Z,Zhou Z,Xu N

更新日期：2019-09-01 00:00:00

abstract：:Active nucleo-cytoplasmic transport is mediated by dynamic signal-mediated pathways. We investigated the effects of transcription inhibitors or fluorescent lectins on nuclear import mediated by nuclear localization signals (NLSs). Therefore, a novel experimental approach that allows the controlled sequential introduct...

journal_title：Journal of cellular biochemistry

authors： Stauber RH,Krätzer F,Schneider G,Hirschmann N,Hauber J,Rosorius O

更新日期：2001-01-01 00:00:00

abstract：:Nuclear receptor coactivator 5 (NCOA5) specifically enhances estrogen receptor α-modulated transcriptional activity. As a novel tumor suppressor, depletion of NCOA5 is associated with the development of a variety of tumors, but its function in cervical cancer is currently unclear. In this study, we addressed how expre...

journal_title：Journal of cellular biochemistry

authors： Liang Y,Zhang T,Shi M,Zhang S,Guo Y,Gao J,Yang X

更新日期：2019-04-01 00:00:00

abstract：:This study aimed to elucidate the precise mechanisms underlying the protective effects of phosphoseryl-tRNA kinase (PSTK) against cisplatin-induced podocyte injury. PSTK overexpression and knockdown vectors were generated and transfected into murine podocyte cells-5. PSTK levels were measured, and transcriptome sequen...

journal_title：Journal of cellular biochemistry

authors： Zheng D,Zhao Y,Liu L,Sun X,Xia Y,Sun L,Xie K

更新日期：2019-06-01 00:00:00

abstract：:Sonic hedgehog (Shh) is a key signal protein in early embryological patterning of limb bud development. Its analog, Indian hedgehog (Ihh), primarily expressed during early cartilage development in prehypertrophic chondrocytes, regulates proliferation and suppresses terminal differentiation of postnatal growth plate (G...

journal_title：Journal of cellular biochemistry

authors： Wu LN,Lu M,Genge BR,Guo GY,Nie D,Wuthier RE

更新日期：2002-01-01 00:00:00

abstract：:Breast cancer cells preferentially metastasize to bone, leading to the formation of primarily osteolytic lesions. Osteoprotegerin (OPG) plays multifactorial roles in the development of osteolytic bone metastases. An increase in the ratio of receptor activator of nuclear factor kappaB ligand (RANKL) to OPG increases os...

journal_title：Journal of cellular biochemistry

authors： Kapoor P,Suva LJ,Welch DR,Donahue HJ

更新日期：2008-01-01 00:00:00

abstract：:T-box (Tbx)3, a known transcriptional repressor, is a member of a family of transcription factors, which contain a highly homologous DNA binding domain known as the Tbx domain. Based on the knowledge that mutation of the Tbx3 gene results in limb malformation, Tbx3 regulates osteoblast proliferation and its expression...

journal_title：Journal of cellular biochemistry

authors： Govoni KE,Linares GR,Chen ST,Pourteymoor S,Mohan S

更新日期：2009-02-15 00:00:00

abstract：:Alkaptonuria (AKU) is a rare genetic disease associated with the accumulation of homogentisic acid (HGA) and its oxidized/polymerized products in connective tissues up to the deposition of melanin-like pigments (ochronosis). Since little is known on the effects of HGA and its metabolites on articular cells, we carried...

journal_title：Journal of cellular biochemistry

authors： Braconi D,Laschi M,Taylor AM,Bernardini G,Spreafico A,Tinti L,Gallagher JA,Santucci A

更新日期：2010-11-01 00:00:00

abstract：:Ligamentum flavum (LF)-derived mesenchymal stem cells (MSCs) have been implicated in the pathogenesis of calcification of the ligamentum flavum (CLF) leading to the increased presence of chondrocyte-like cells and calcium deposition in CLF; however, the mechanisms of LF-MSCs in differentiation are not defined. In this...

journal_title：Journal of cellular biochemistry

authors： Zhang Q,Wang S,Sheng Y,Zhao S,Jiang Y,Zhou D,Yang H

更新日期：2019-03-01 00:00:00

abstract：:Cervical cancer is one of the leading female health-killers among all types of malignancies globally. Human papillomavirus infection combined with genetic and epigenetic alterations have been indicated to be closely associated with the pathogenesis, progression, and malignant transformation of cervical cancer. Notably...

journal_title：Journal of cellular biochemistry

authors： Li C,Ke J,Liu J,Su J

更新日期：2020-03-01 00:00:00

abstract：:Recombinant human apolipoprotein E3 (apoE), purified from E. coli, inhibited the proliferation of several cell types, including endothelial cells and tumor cells in a dose- and time-dependent manner. ApoE inhibited both de novo DNA synthesis and proliferation as assessed by an increase in cell number. Maximal inhibiti...

journal_title：Journal of cellular biochemistry

authors： Vogel T,Guo NH,Guy R,Drezlich N,Krutzsch HC,Blake DA,Panet A,Roberts DD

更新日期：1994-03-01 00:00:00

abstract：:Altered expression of ABH blood group substances is a common feature of human colorectal carcinoma, yet it remains unclear how these structural changes influence the biological properties of tumor cells. Azoxymethane-induced rat colon tumors display many features of the human disease, thereby providing a potentially u...

journal_title：Journal of cellular biochemistry

authors： Laferté S,Prokopishyn NL,Moyana T,Bird RP

更新日期：1995-01-01 00:00:00

abstract：:Survivin is recognized as an attractive target in cancer therapy because of its selective overexpression in the majority of tumors. Upregulated expression of this protein correlates with increased tumor grade, recurrence risk and decreased cancer patients survival. In this study, we assessed the efficacy of two surviv...

journal_title：Journal of cellular biochemistry

authors： Croci DO,Cogno IS,Vittar NB,Salvatierra E,Trajtenberg F,Podhajcer OL,Osinaga E,Rabinovich GA,Rivarola VA

更新日期：2008-10-01 00:00:00

abstract：:Arsenic trioxide (ATO) is a first-line anti-cancer agent for acute promyelocytic leukemia, and induces apoptosis in other solid cancer cell lines including breast cancer cells. However, as with arsenites found in drinking water and used as raw materials for wood preservatives, insecticides, and herbicides, low doses o...

journal_title：Journal of cellular biochemistry

authors： Liu Y,Hock JM,Sullivan C,Fang G,Cox AJ,Davis KT,Davis BH,Li X

更新日期：2010-12-15 00:00:00

abstract：:The conversion of expandable liver progenitor cells into pancreatic beta cells would provide a renewable cell source for diabetes cell therapy. Previously, we reported the establishment of liver epithelial progenitor cells (LEPCs). In this work, LEPCs were modified into EGFP/Pdx-1 LEPCs, cells with stable expression o...

journal_title：Journal of cellular biochemistry

authors： Jin CX,Li WL,Xu F,Geng ZH,He ZY,Su J,Tao XR,Ding XY,Wang X,Hu YP

更新日期：2008-05-01 00:00:00

abstract：:The lysosomal cysteine protease cathepsin B is implicated in degradation of extracellular matrix (ECM), a crucial step in a variety of physiological and pathological processes, including tumor dissemination and angiogenesis. In this study, we analyzed the contribution of extracellular and intracellular cathepsin B act...

journal_title：Journal of cellular biochemistry

authors： Premzl A,Turk V,Kos J

更新日期：2006-04-15 00:00:00

abstract：:Fibronectin (FN) is an extracellular matrix (ECM) glycoprotein that self-assembles into FN fibrils, forming a FN matrix contributing to the stiffness of the ECM. Stromal FN stiffness in cancer has been shown to impact epithelial functions such as migration, cancer metastasis, and epithelial-to-mesenchymal transition. ...

journal_title：Journal of cellular biochemistry

authors： Magdaleno C,House T,Pawar JS,Carvalho S,Rajasekaran N,Varadaraj A

更新日期：2021-01-13 00:00:00

abstract：:The promoter of the mouse thymidylate synthase (TS) gene lacks a TATAA box and an initiator element, is bidirectional and initiates transcription at multiple start sites across broad initiation windows upstream and downstream of the 30 nt essential promoter region. The TS promoter also plays an essential role in the p...

journal_title：Journal of cellular biochemistry

authors： Kapadia F,Johnson LF

更新日期：2006-02-15 00:00:00

abstract：:The adipocyte secreted hormone leptin (OB) and its receptor (OB-R) are key regulators of mammalian body weight homeostasis. Two predominant isoforms of OB-R have been described: long form (OB-R(L)) characterized as a signal transducing receptor that is highly expressed in specific nuclei of the hypothalamus; and a sho...

journal_title：Journal of cellular biochemistry

authors： White DW,Tartaglia LA

更新日期：1999-05-01 00:00:00