Abstract：
BACKGROUND:Little is known about epidemiology of carbapenemase-producing Enterobacteriaceae (CPE) in children. Aim of this study was to describe CPE epidemiology in a tertiary care pediatric hospital in Italy that admits patients coming from geographic areas with high diffusion of CPE. METHODS:Prospective evaluation of the proportion and rates per 100,000 hospital discharges (D) or hospitalization-days (HD) of invasive infections due to CPE from 2013 to 2017 and of CPE infections and colonizations from 2014 to 2017. Disease-preventing strategies comprised patients' screening at admission, pre-emptive contact isolation precautions pending cultures results, and bundles for prevention of healthcare associated infections. RESULTS:From 2013 to 2017 CPE represented 3.5% of all invasive infections due to Enterobacteriaceae, with rates ranging 7.30-14.33 for D and 1.03-2.06 for HD, without major changes over time. On the contrary, overall rates of isolates increased from 83.03 to 191.34 for D and from 12.21 to 28.35 for HD. The intra-hospital diffusion consisted of 2 small outbreaks without invasive diseases in 2014-2015, and sporadic, not epidemiologically-related cases in 2016-2017. Globally, Escherichia coli and Klebsiella pneumoniae represented 64% of identified CPE, while 70% of carbapenemases identified were metallo-beta-lactamases (VIM or NDM), with changes over time. CONCLUSIONS:In our center metallo-beta lactamases were the most frequently identified carbapenemases in Enterobacteriaceae and E. coli and K. pneumoniae the most frequently isolated pathogens carrying these enzymes. A proactive management strategy was effective in containing in-hospital spreading.
journal_name
J Infect Public Healthjournal_title
Journal of infection and public healthauthors
Castagnola E,Tatarelli P,Mesini A,Baldelli I,La Masa D,Biassoni R,Bandettini Rdoi
10.1016/j.jiph.2018.11.003subject
Has Abstractpub_date
2019-01-01 00:00:00pages
270-274issue
2eissn
1876-0341issn
1876-035Xpii
S1876-0341(18)30311-3journal_volume
12pub_type
杂志文章abstract：:Zika virus (ZIKV), an Aedes mosquito-borne flavivirus, has captured public health attention worldwide. Initially, the virus was reported in Africa and Asia. However, the outbreak of ZIKV in Brazil and the United States of America demonstrated the global health risk. Symptoms of ZIKV infection vary from mild fever, ras...
journal_title：Journal of infection and public health
pub_type： 杂志文章,评审
doi：10.1016/j.jiph.2019.05.004
更新日期：2019-01-01 00:00:00
abstract：:Diagnosis of MERS-Cov still a major concern in most of daignostic laboratories. To date the Real-time Polymerase Chain reaction (RT-PCR) is the mainstay for diagnosis of MERS-CoV. RT-PCR has limitations, including a long turnaround time and lack of common measurements and correlations with Viral Load (VL). It is recom...
journal_title：Journal of infection and public health
pub_type： 杂志文章,评审
doi：10.1016/j.jiph.2016.04.005
更新日期：2016-05-01 00:00:00
abstract：BACKGROUND:Carbapenem are the last-line antibiotic, defence against Gram-negative extended spectrum ß-lactamases producers (ESBLs). Carbapenem resistance Enterobacteriaceae especially Carbapenem resistant-Klebsiella pneumoniae (CR-KP) is recognized as one of the well-known public health problem, which is increasingly b...
journal_title：Journal of infection and public health
pub_type： 杂志文章
doi：10.1016/j.jiph.2020.09.018
更新日期：2020-11-21 00:00:00
abstract：:Rhinocerebral or sinopulmonary mucromycosis is a well-recognized human fungal infection found among immunocompromised and diabetic patients. However, the infection is rare among immunocompetent hosts. We are reporting the case of an adult immunocompetent male patient working as an air-conditioning technician. The pati...
journal_title：Journal of infection and public health
pub_type： 杂志文章,评审
doi：10.1016/j.jiph.2011.10.002
更新日期：2012-03-01 00:00:00
abstract：OBJECTIVES:Incidence of tuberculosis (TB) is greatest among patients with impaired immunity. India is experiencing a double epidemic of HIV and diabetes mellitus (DM), both of which are strongly associated with immuno-suppression. This study aimed to discover the prevalence of HIV and DM in both the pulmonary and extra...
journal_title：Journal of infection and public health
pub_type： 杂志文章
doi：10.1016/j.jiph.2011.03.005
更新日期：2011-08-01 00:00:00
abstract：BACKGROUND:Natural products derived from marine microbes have more potential toward to treatment of various diseases. Among the microbes, the secondary metabolites recovered from the marine actinomycetes were more added values. OBJECTIVE:A promising antimicrobial metabolite producing filamentous actinomycete SCA-7 rec...
journal_title：Journal of infection and public health
pub_type： 杂志文章
doi：10.1016/j.jiph.2019.07.002
更新日期：2020-01-01 00:00:00
abstract：BACKGROUND:Although the specific etiology of Henoch-Schonlein purpura (HSP) is still unknown, several kinds of infectious triggers have been proved to participate in its pathogenesis. The objectives of present study were to analyze the association of the infectious triggers with childhood HSP in Anhui province, China. ...
journal_title：Journal of infection and public health
pub_type： 杂志文章
doi：10.1016/j.jiph.2019.07.004
更新日期：2020-01-01 00:00:00
abstract：:The purpose of this study was to evaluate the observed incidence of acute kidney injury (AKI) in adult patients receiving either piperacillin-tazobactam (PT) and vancomycin or meropenem and vancomycin for at least 48h. In this retrospective cohort study, we included adult patients with no known renal dysfunction who r...
journal_title：Journal of infection and public health
pub_type： 杂志文章
doi：10.1016/j.jiph.2016.11.007
更新日期：2017-01-01 00:00:00
abstract：BACKGROUND:The aim of this study was to estimate the attributable risk for all-cause mortality in hypertensive adults living in Beijing, China. METHODS:We conducted a prospective cohort study on the basis of the disease risk prediction model, which included 3006 hypertensive patients aged 50 and over who participated ...
journal_title：Journal of infection and public health
pub_type： 杂志文章
doi：10.1016/j.jiph.2019.12.010
更新日期：2020-09-01 00:00:00
abstract：:We present a case which highlights several areas of concern relating to the prevention and management of varicella in Ireland. We review the pathophysiology of this virus and highlight its greater potential for morbidity in certain groups, most particularly adult males. The experience and opinions with regard to varic...
journal_title：Journal of infection and public health
pub_type： 杂志文章,评审
doi：10.1016/j.jiph.2010.07.001
更新日期：2010-01-01 00:00:00
abstract：:Although rare, infective endocarditis (IE) continues to cause significant morbidity and mortality. Previous data from the American University of Beirut Medical Center (AUBMC) had shown predominance of streptococcal infection. As worldwide studies in developed countries show increasing trends in Staphylococcus aureus e...
journal_title：Journal of infection and public health
pub_type： 杂志文章
doi：10.1016/j.jiph.2016.11.017
更新日期：2017-01-01 00:00:00
abstract：OBJECTIVE:The objective of this study was to evaluate the microbial quality of the well water used as a drinking source in urban and rural households. METHODS:A total of 80 household well water samples were analyzed by the multiple fermentation tube method to determine the presumptive coliform count/most probable numb...
journal_title：Journal of infection and public health
pub_type： 杂志文章
doi：10.1016/j.jiph.2012.03.004
更新日期：2012-06-01 00:00:00
abstract：:The objectives of the study was to determine the types, challenges and implications of surveillance methods for controlling Covid-19 pandemic. An integrative article review was done. The source of data were documents from WHO, Euro-surveillance, CDC, Saudi CDC, MOH, and journals from PubMed, Medline, etc. The inclusio...
journal_title：Journal of infection and public health
pub_type： 杂志文章,评审
doi：10.1016/j.jiph.2020.07.019
更新日期：2020-11-01 00:00:00
abstract：BACKGROUND:Panton-Valentine Leukocidin (PVL), is one of the virulence gene expressed by Methicillin Resistant Staphylococcus aureus (MRSA) and is known to be associated with severe form of community acquired MRSA infection. The aim of this study is to investigate its prevalence in our setting and patient's clinical out...
journal_title：Journal of infection and public health
pub_type： 杂志文章
doi：10.1016/j.jiph.2020.06.018
更新日期：2020-10-01 00:00:00
abstract：:Repeat HAIs among frequently hospitalized patients may be contributing to the high rates of antibiotic resistance seen in gram-negative bacteria (GNB) in hospital settings. This systematic review examines the state of the literature assessing the association between repeat GNB HAIs and changes in antibiotic susceptibi...
journal_title：Journal of infection and public health
pub_type： 杂志文章,评审
doi：10.1016/j.jiph.2017.09.024
更新日期：2018-01-01 00:00:00
abstract：:Dialysis patients are more likely than the general population to develop active tuberculosis (TB). In these patients, the availability of a highly sensitive and specific test to diagnose latent TB will ensure earlier treatment and decreased progression to active disease. In the current study, the Quanti-FERON-TB Gold ...
journal_title：Journal of infection and public health
pub_type： 杂志文章
doi：10.1016/j.jiph.2013.02.002
更新日期：2013-06-01 00:00:00
abstract：:This study aimed to assess the level of knowledge, attitudes, and practices (KAP) concerning malaria and malaria prevention among rural populations residing in the southwestern region of Saudi Arabia. This was a household-based cross-sectional survey, using structured questionnaire that was developed and distributed a...
journal_title：Journal of infection and public health
pub_type： 杂志文章
doi：10.1016/j.jiph.2016.09.021
更新日期：2017-01-01 00:00:00
abstract：:To study the nursing effects of different CT angiography (CTA) technology-based nursing methods on patients with coronary artery heart diseases (CHD), CHD patients treated in Dongying People's Hospital were selected as the research objects and were divided into the control group and the observation group. Different co...
journal_title：Journal of infection and public health
pub_type： 杂志文章
doi：10.1016/j.jiph.2019.06.023
更新日期：2020-12-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Lymphadenopathy is a common medical problem. A lymph node biopsy may be necessary for definitive diagnosis in selected cases. METHODS:The study group included a retrospective, hospital-based series of patients who had a cervical lymph node biopsy at the Saudi Aramco Medical Services organizati...
journal_title：Journal of infection and public health
pub_type： 杂志文章
doi：10.1016/j.jiph.2011.11.006
更新日期：2012-04-01 00:00:00
abstract：:Hand washing is widely accepted as the cornerstone of infection control in the intensive care unit (ICU). Nosocomial infections are frequently viewed as indicating poor compliance with hand washing guidelines. To determine the hand hygiene (HH) compliance rate among healthcare workers (HCWs) and its effect on the noso...
journal_title：Journal of infection and public health
pub_type： 杂志文章
doi：10.1016/j.jiph.2012.09.014
更新日期：2013-02-01 00:00:00
abstract：:This study focused on 77 isolates of Salmonella enterica serotype Enteritidis collected during 2009 to 2013 from healthy and sick chickens and environmental farm samples in Tunisia. Resistance to 14 antimicrobials and the encoding genes were analyzed. 66, 26, 6.5, 3.9 and 1.3% were pan-susceptible or showed resistance...
journal_title：Journal of infection and public health
pub_type： 杂志文章
doi：10.1016/j.jiph.2017.01.012
更新日期：2017-01-01 00:00:00
abstract：:A man, 26years-old, presented fever, mental confusion and a progressively worsening headache 6days prior to admission. The CSF study was suggestive of meningoencephalitis, the PCR study revealed presence of HSV-1 and ZIKV, while other immunology tests were negative. ZIKV was also identified in serum. The MRI showed te...
journal_title：Journal of infection and public health
pub_type： 杂志文章,评审
doi：10.1016/j.jiph.2018.04.010
更新日期：2019-01-01 00:00:00
abstract：:To evaluate the efficacy and safety of a new domestic dacron patch in the surgical treatment of congenital heart disease (CHD) with infective endocarditis (IE), a clinical controlled trial is conducted. 48 patients with CHD complicated with IE are selected and randomly divided into two groups. 26 patients in the exper...
journal_title：Journal of infection and public health
pub_type： 杂志文章
doi：10.1016/j.jiph.2019.08.009
更新日期：2020-12-01 00:00:00
abstract：BACKGROUND:Identified in 2001, Human Metapneumovirus (HMPV) is a Pneumovirus associated with acute lower and upper respiratory infections in all age groups and especially in newborns, elderly and immunocompromised subjects. Data are still limited in sub-Saharan African countries genetic characterization of this respira...
journal_title：Journal of infection and public health
pub_type： 杂志文章
doi：10.1016/j.jiph.2019.08.018
更新日期：2020-04-01 00:00:00
abstract：BACKGROUND:Due to the increasing availability of antiretroviral treatment, HIV infected children are living longer which points out the necessity of disclosure. And which is important to support the uptake and adherence to treatment. Disclosure is an important measure to prevent secondary transmission when children are...
journal_title：Journal of infection and public health
pub_type： 杂志文章
doi：10.1016/j.jiph.2019.05.018
更新日期：2019-01-01 00:00:00
abstract：:We report a case of Pseudomonas stutzeri endocarditis in Lebanon. The patient had a recent history of prosthetic aortic valve replacement and presented to the emergency department with fever and chills. Transesophageal echocardiography confirmed the presence of a vegetation on the prosthetic valve and blood cultures y...
journal_title：Journal of infection and public health
pub_type： 杂志文章,评审
doi：10.1016/j.jiph.2018.07.004
更新日期：2019-01-01 00:00:00
abstract：BACKGROUND:Vaccine-related diseases are increasing in developing countries. This study aimed to explore parents' reasons for refusal of childhood vaccinations in Malaysia and their recommendations on addressing their concerns. METHODS:A qualitative study design involving individual both face-to-face and online in-dept...
journal_title：Journal of infection and public health
pub_type： 杂志文章
doi：10.1016/j.jiph.2019.07.027
更新日期：2020-02-01 00:00:00
abstract：:The objective of the study was to determine the level of Knowledge, Attitude and Practice (KAP) of patients attended dental clinics at King Abdulaziz University Hospital (KAUH) regarding cross infections and infection control in dentistry. A cross-sectional study was conducted among 225 patients who attended the denta...
journal_title：Journal of infection and public health
pub_type： 杂志文章
doi：10.1016/j.jiph.2016.06.002
更新日期：2017-01-01 00:00:00
abstract：:We report the case of a 10-year-old girl who presented to the emergency department with acute abdominal pain. She was diagnosed as having extrapulmonary tuberculosis (TB) with multifocal osteomyelitis of the spine and ribs, peritonitis and intestinal involvement. We describe the clinical presentation of this unusual c...
journal_title：Journal of infection and public health
pub_type： 杂志文章
doi：10.1016/j.jiph.2011.11.005
更新日期：2012-04-01 00:00:00
abstract：BACKGROUND:Enteric caliciviruses, including noroviruses (NoVs) and sapoviruses (SaVs) are the most significant pathogens associated with waterborne and foodborne outbreaks of nonbacterial acute gastroenteritis in humans worldwide. METHODS:In this study, 126 environmental water samples collected from 6 different source...
journal_title：Journal of infection and public health
pub_type： 杂志文章
doi：10.1016/j.jiph.2020.05.004
更新日期：2020-10-01 00:00:00
