Abstract:
BACKGROUND:Although the specific etiology of Henoch-Schonlein purpura (HSP) is still unknown, several kinds of infectious triggers have been proved to participate in its pathogenesis. The objectives of present study were to analyze the association of the infectious triggers with childhood HSP in Anhui province, China. METHODS:1200 HSP children were recruited from January 2015 to December 2017. Serum antistreptolysin O titer, TORCH, Epstein-Barr virus, helicobacter pylori (HP), Mycoplasma antibodies (MP-Ab), tubercle bacillus antibody (TB-Ab), respiratory pathogens (legionella pneumophila, chlamydia pneumoniae, adenovirus, respiratory syncytial virus, influenza A virus, influenza B virus, rickettsia, parainfluenza virus) were determined. Patients' histories were obtained by interviews and questionnaires. RESULTS:The annual incidence of HSP was 8.13-9.17 per 100,000. HSP occurred more commonly in spring and winter than in summer with an obvious west-to-east gradient. On admission, several potential infections were identified in 611 cases (50.92%). The infectious agents including streptococcus, HP, MP, parainfluenza, respiratory syncytial virus, TB and toxoplasma gondii were identified in 205 cases (17.08%), 71 cases (5.92%), 58 cases (4.83%), 6 cases (0.5%), 1 case (0.08%), 1 case (0.08%) and 1 case (0.08%) respectively. 123 cases (10.25%) relapsed or recurred more than one time; the mean number was 2.92, and the mean interval was 11.4 weeks. The infection was the most frequent trigger regardless of clinical phenotypes and relapse/recurrence. Symptomatic treatment plus adjunctive anti-infectious agents could significantly improve the remission rate of purpura in the infectious cases (x2=24.60, p<0.01). CONCLUSIONS:Streptococcus is the most frequent infectious agent in HSP children regardless of clinical phenotype or relapse/recurrence. The complete elimination of infectious triggers may help relieve cutaneous purpura.
journal_name
J Infect Public Healthjournal_title
Journal of infection and public healthauthors
Wang JJ,Xu Y,Liu FF,Wu Y,Samadli S,Wu YF,Luo HH,Zhang DD,Hu Pdoi
10.1016/j.jiph.2019.07.004subject
Has Abstractpub_date
2020-01-01 00:00:00pages
110-117issue
1eissn
1876-0341issn
1876-035Xpii
S1876-0341(19)30237-0journal_volume
13pub_type
杂志文章abstract::The aim of our study was to describe the distribution of Visceral Leishmaniasis (VL) in Italy, focusing on HIV-infected patients, to estimate the burden of the disease and the public health actions that should be undertaken. A review of official notifications and hospitalization data has been performed. From 2006 to 2...
journal_title:Journal of infection and public health
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doi:10.1016/j.jiph.2013.03.004
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abstract:BACKGROUND:Cytomegalovirus (CMV) is a rare cause of prolonged febrile neutropenia (PFN) among pediatric oncology patients, especially in non-stem cell transplant setting (Non-SCTS). Infectious Diseases Society of America (IDSA) guidelines stated briefly that neutropenia is not considered as an indication of CMV re-acti...
journal_title:Journal of infection and public health
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abstract::Dengue fever (DF) is the most serious mosquito-borne viral disease worldwide. DF is an acute febrile illness caused by Aedes aegypti and Aedes albopictus, which are endemic in certain cities of Saudi Arabia, such as Jeddah and Makkah (Mecca). An online literature search was conducted using relevant keywords to retriev...
journal_title:Journal of infection and public health
pub_type: 杂志文章,评审
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abstract:BACKGROUND:Respiratory viral infections (RVI) are a leading cause of mortality worldwide. We compared the epidemiology and severity of RVI in Ecuador during 2009-2016. METHODS:Respiratory specimens collected within the national surveillance system were tested for influenza viruses, respiratory syncytial virus (RSV), a...
journal_title:Journal of infection and public health
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abstract::Carbapenemase-producing Enterobacteriaceae have been steadily spreading worldwide during the last decade. Nine patients were identified prospectively and were followed during their hospitalization course to identify the epidemiology, clinical profiles and outcomes. These patients had one or more cultures positive for ...
journal_title:Journal of infection and public health
pub_type: 杂志文章
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abstract:BACKGROUND:Panton-Valentine Leukocidin (PVL), is one of the virulence gene expressed by Methicillin Resistant Staphylococcus aureus (MRSA) and is known to be associated with severe form of community acquired MRSA infection. The aim of this study is to investigate its prevalence in our setting and patient's clinical out...
journal_title:Journal of infection and public health
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abstract:BACKGROUND:Throughout the world multi drug resistant nosocomial infections are one of the leading causes of death and morbidity among hospitalized patients. Antimicrobial resistance [AMR] has become a major problem in treatment of such infections. High consumption of antimicrobials particularly in ICUs is often describ...
journal_title:Journal of infection and public health
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abstract:BACKGROUND:Swine brucellosis is a zoonotic disease caused by Brucella suis. The study describes the occurrence of brucellosis in two organized piggeries in Southern India. METHODS:A total of 585 serum samples comprising 575 from pigs and 10 from animal handlers were collected and tested by serological tests and PCR. T...
journal_title:Journal of infection and public health
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abstract:BACKGROUND:Escherichia coli sequence type 131 is an important multidrug resistant clone responsible from more than half of ESBL-producing E.coli isolates. Aim of this study was to investigate the presence of O25b-ST131 clone, CTX-M-15 and CTX-M-1 genes in the E. coli strains isolated from both hospital and community ac...
journal_title:Journal of infection and public health
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journal_title:Journal of infection and public health
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abstract:BACKGROUND:Identified in 2001, Human Metapneumovirus (HMPV) is a Pneumovirus associated with acute lower and upper respiratory infections in all age groups and especially in newborns, elderly and immunocompromised subjects. Data are still limited in sub-Saharan African countries genetic characterization of this respira...
journal_title:Journal of infection and public health
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abstract:OBJECTIVES:To assess the impact of a multidimensional infection control approach on the reduction of catheter-associated urinary tract infection (CAUTI) rates in adult intensive care units (AICUs) in two hospitals in the Philippines that are members of the International Nosocomial Infection Control Consortium. MATERIA...
journal_title:Journal of infection and public health
pub_type: 杂志文章
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journal_title:Journal of infection and public health
pub_type: 杂志文章,评审
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journal_title:Journal of infection and public health
pub_type: 杂志文章
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abstract:BACKGROUND:Plasmodium vivax malaria accounts for 80% of the malaria cases in Delhi, India. The gene merozoite surface protein 3 alpha (MSP3α) is highly polymorphic and has been used as marker in many P. vivax population studies. METHODS:MSP3α has been used to assess the genetic diversity of P. vivax samples from Delhi...
journal_title:Journal of infection and public health
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更新日期:2019-01-01 00:00:00
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journal_title:Journal of infection and public health
pub_type: 杂志文章
doi:10.1016/j.jiph.2014.07.004
更新日期:2014-11-01 00:00:00
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journal_title:Journal of infection and public health
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journal_title:Journal of infection and public health
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journal_title:Journal of infection and public health
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journal_title:Journal of infection and public health
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journal_title:Journal of infection and public health
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abstract::In Minas Gerais, Brazil, almost 500,000 dengue fever cases were reported to the State Surveillance System between November 2012 and July 2013. An analysis of the laboratory-confirmed cases revealed a higher age-specific incidence in adults and a higher case fatality rate in people aged ≥50. Dengue virus serotypes 1 an...
journal_title:Journal of infection and public health
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abstract::Hand washing is widely accepted as the cornerstone of infection control in the intensive care unit (ICU). Nosocomial infections are frequently viewed as indicating poor compliance with hand washing guidelines. To determine the hand hygiene (HH) compliance rate among healthcare workers (HCWs) and its effect on the noso...
journal_title:Journal of infection and public health
pub_type: 杂志文章
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更新日期:2013-02-01 00:00:00
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journal_title:Journal of infection and public health
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更新日期:2014-09-01 00:00:00
abstract::The human stomach is colonized by diverse bacterial species. The presence of non-Helicobacter pylori bacteria in urease-positive biopsies of individuals has been reported. Bacteria belonging to the Ochrobactrum genus have been documented in the human gastric niche. The co-occurrence of Ochrobactrum spp. with H. pylori...
journal_title:Journal of infection and public health
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abstract::The emergence of drug-resistant tuberculosis (TB) is an increasing problem which adversely affects patient care and public health. This study aimed to determine the rates and patterns of primary anti-TB drugs resistance in Najran, Southwestern Saudi Arabia. The study included 80 smear-positive new pulmonary TB patient...
journal_title:Journal of infection and public health
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更新日期:2012-08-01 00:00:00
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journal_title:Journal of infection and public health
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abstract::Brucellosis is an ancient disease that still remains a significant threat to humans and is typically linked to exposure to infected animals and/or consumption of unpasteurized animal products. Despite this history, we have a relatively limited understanding of the host characteristics of this disease; consequently, fu...
journal_title:Journal of infection and public health
pub_type: 杂志文章
doi:10.1016/j.jiph.2012.03.006
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abstract:BACKGROUND:Due to the increasing availability of antiretroviral treatment, HIV infected children are living longer which points out the necessity of disclosure. And which is important to support the uptake and adherence to treatment. Disclosure is an important measure to prevent secondary transmission when children are...
journal_title:Journal of infection and public health
pub_type: 杂志文章
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更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Human immunodeficiency virus (HIV) is an important risk factor for the global incidence and mortality of tuberculosis (TB) and has had a tremendous impact on the epidemiology and the control of the disease. The purpose of this study was to determine the demographic, laboratory and clinical characteristics of...
journal_title:Journal of infection and public health
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