Pediatric toxic epidermal necrolysis treated successfully with infliximab.

Abstract:

:Successful management of toxic epidermal necrolysis (TEN) with tumor necrosis factor-α inhibitors has been described in adults. We present a case of a 7-year-old boy with infection-associated TEN, diagnosed by typical clinical and histopathological features, most likely caused by Mycoplasma pneumoniae. Treatment with a single dose of infliximab 5 mg/kg intravenously on day 5 after the onset of symptoms was followed by cessation of all blister formation over 3 days and complete resolution within a week. Sequelae were mild, consisting of postinflammatory hyperpigmentation and dry eyes.

journal_name

Pediatr Dermatol

journal_title

Pediatric dermatology

authors

Chafranska L,Saunte DM,Behrendt N,Nygaard U,Christensen RJ,Sand C,Jemec GB

doi

10.1111/pde.13778

subject

Has Abstract

pub_date

2019-05-01 00:00:00

pages

342-345

issue

3

eissn

0736-8046

issn

1525-1470

journal_volume

36

pub_type

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