Orofacial granulomatosis in a 12-year-old girl successfully treated with intravenous pulse corticosteroid therapy and chloroquine.

Abstract:

:Orofacial granulomatosis, a rare disease in childhood, is characterized by orofacial swelling in the absence of systemic disease. We report the case of a 12-year-old girl with asymptomatic erythematous infiltration of her upper lip, cheeks, and chin that had persisted for more than 2 years; biopsy confirmed granuloma formation. Because a large area was affected, intralesional corticosteroids were inappropriate and six cycles of 3-day intravenous pulse corticosteroid therapy (dexamethasone 1.5mg/kg), repeated once after 4 weeks, was given. Our patient also received oral chloroquine and topical emollients. At the end of the sixth pulse cycle, the infiltration had completely resolved, leaving slight residual erythema.

journal_name

Pediatr Dermatol

journal_title

Pediatric dermatology

authors

Lalosevic J,Gajic-Veljic M,Nikolic M

doi

10.1111/pde.13279

subject

Has Abstract

pub_date

2017-11-01 00:00:00

pages

e324-e327

issue

6

eissn

0736-8046

issn

1525-1470

journal_volume

34

pub_type

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