Abstract:
:Pyoderma gangrenosum (PG) is an inflammatory neutrophilic dermatosis that may present with limited to severe disease, posing a therapeutic challenge. A 7-year-old African female who presented with extensive PG showed a remarkable response to corticosteroid wrap monotherapy.
journal_name
Pediatr Dermatoljournal_title
Pediatric dermatologyauthors
Chateau A,Makhubele J,Dlova Ndoi
10.1111/pde.14348subject
Has Abstractpub_date
2020-09-06 00:00:00eissn
0736-8046issn
1525-1470pub_type
abstract::Knowledge of the molecular underpinnings of many epidermal nevi and epidermal nevus syndrome has expanded rapidly in recent years. In this review and update on epidermal nevus syndrome, we will cover recent genetic discoveries involving epidermal nevi, including nevus sebaceus, keratinocytic epidermal nevus, nevus com...
journal_title:Pediatric dermatology
pub_type: 杂志文章,评审
doi:10.1111/pde.13273
更新日期:2018-01-01 00:00:00
abstract::We report a 10-month-old boy who presented with a giant perianal condyloma acuminatum, and a similar lesion on the neck. These lesions were treated by surgical excision with satisfactory results. This size, extent, and early age of appearance make this case highly unusual. ...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/j.1525-1470.2009.00968.x
更新日期:2009-07-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Epidemiologic studies of children with alopecia areata (AA) are sparse, and there are no studies that focus on the youngest children with AA. Evaluation of the clinical presentations of AA in children <4 years of age was performed in order to identify the prognostic factors for disease progression...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/pde.13990
更新日期:2019-11-01 00:00:00
abstract::Although lentigines are usually benign, they can be associated with a number of genetic syndromes in which neoplasms and other multi-system pathological processes occur. Here, we report the case of a 6-year-old girl who presented with atypical lentiginosis and hyperpigmentation caused by a de novo genetic variant in t...
journal_title:Pediatric dermatology
pub_type:
doi:10.1111/pde.13952
更新日期:2019-11-01 00:00:00
abstract::Infliximab, a chimeric antitumor necrosis factor alpha monoclonal antibody (anti-TNF alpha), has been recently shown to have a beneficial effect on pyoderma gangrenosum associated with inflammatory bowel disease. Patients with the syndromic triad of pyogenic sterile arthritis, pyoderma gangrenosum, and acne, an autoin...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/j.1525-1470.2005.22320.x
更新日期:2005-05-01 00:00:00
abstract:BACKGROUND:Different skin manifestations of COVID-19 are being reported. Acral lesions on the hands and feet, closely resembling chilblains, have been recognized during the peak incidence of the COVID-19 pandemic. MATERIAL AND METHODS:A retrospective review of 22 children and adolescents with chilblain-like lesions se...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/pde.14215
更新日期:2020-05-01 00:00:00
abstract::Aeromonas species are ubiquitous, facultative, anaerobic, gram-negative flagellated rods, mainly found in aquatic ecosystems worldwide. Skin and soft-tissue infections, including cellulitis and wound infections, are the second most frequent location of isolations of Aeromonas spp. in clinical samples, after the gastro...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/j.1525-1470.2009.00993.x
更新日期:2009-09-01 00:00:00
abstract::Hidradenitis suppurativa is a chronic relapsing disorder of follicular occlusion that is often recalcitrant to therapy. Topical and systemic antibiotics, hormonal therapies, oral retinoids, immunosuppressant agents, and surgical treatment are some of the therapeutic alternatives used for this often recalcitrant and fr...
journal_title:Pediatric dermatology
pub_type: 杂志文章,评审
doi:10.1111/j.1525-1470.2007.00544.x
更新日期:2007-09-01 00:00:00
abstract::Acquired progressive lymphangioma (APL), or benign lymphangioendothelioma, is an unusual entity derived from vascular structures. Clinically and histopathologically it may resemble Kaposi's sarcoma and well-differentiated angiosarcoma, causing a diagnostic problem. We report an individual with APL initially diagnosed ...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/pde.13283
更新日期:2017-11-01 00:00:00
abstract::Acral peeling skin syndrome (APSS) is a clinically and genetically heterogeneous disorder. We used whole-exome sequencing to identify the molecular basis of APSS in a consanguineous Jordanian-American pedigree. We identified a homozygous nonsense mutation (p.Lys22X) in the CSTA gene, encoding cystatin A, that was conf...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/pde.12092
更新日期:2013-09-01 00:00:00
abstract::We report on four children born with medium to large congenital melanocytic nevi (CMN) with color heterogeneity and irregular surface rugosity. As these patients aged, their nevi evolved to become more homogeneous and lighter in color, and developed a smoother, more even texture. We propose that given this evolution t...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/pde.13745
更新日期:2019-03-01 00:00:00
abstract::Nodular lichen myxedematosus (LM) is a rare disease and is one of the five subtypes of localized LM. It is distinctly characterized by multiple nodules on the trunk and limbs with or without papular lesions. A healthy 6-year-old boy presented with complaints of "knots" on his right chest, upper limb, and thigh for 4 m...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/pde.12376
更新日期:2014-11-01 00:00:00
abstract::An 11-year-old girl with a history of diabetes mellitus type I and celiac disease presented with multiple, depressed patches of purple-brown skin on the right lower extremity and central back, with histopathologic features of early morphea. Though morphea may coexist with other autoimmune diseases, its presentation wi...
journal_title:Pediatric dermatology
pub_type: 杂志文章,评审
doi:10.1111/j.1525-1470.2009.00907.x
更新日期:2010-01-01 00:00:00
abstract::Loose anagen hair syndrome (LAHS) is an uncommonly reported autosomal dominant hair disorder with incomplete penetrance that primarily affects children but is occasionally seen in adults. LAHS is characterized by the ability to easily and painlessly extract unsheathed anagen hairs from the scalp with gentle traction. ...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/pde.12208
更新日期:2013-09-01 00:00:00
abstract::Many supplements and products containing botanical extracts are marketed to patients for the treatment of acne vulgaris. Additionally, increasing attention has been paid to the role of diet in acne vulgaris. Studies on this topic including pediatric patients are limited, with variable efficacy data. Despite these limi...
journal_title:Pediatric dermatology
pub_type: 杂志文章,评审
doi:10.1111/pde.13904
更新日期:2019-09-01 00:00:00
abstract::A newborn boy presented with a progressively infiltrating and painful congenital ulcerated plaque on the back of his left foot. A partial excision was performed and histopathologic examination confirmed a diagnosis of a plexiform fibrohistiocytic tumor. This rare tumor usually appears in children and adolescents, with...
journal_title:Pediatric dermatology
pub_type: 杂志文章,评审
doi:10.1111/pde.13652
更新日期:2018-11-01 00:00:00
abstract::The objective of the study was to determine the prevalence of pediatric human immunodeficiency virus 1 (HIV-1) mucocutaneous manifestations in the era of highly active antiretroviral therapy (HAART). We conducted population-based, prospective, multicenter pediatric HIV-1 surveillance in 276 children with perinatally a...
journal_title:Pediatric dermatology
pub_type: 杂志文章,多中心研究
doi:10.1111/pde.12020
更新日期:2013-07-01 00:00:00
abstract::Orf is a zoonotic parapoxvirus typically transmitted to humans by a bite from goats or sheep. We present an unusual case of multiple orf lesions on the fingers of a 13-month-old child who was bitten by a goat and subsequently developed progressive swelling, blistering, and necrotic papulonodules of the hand followed b...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/pde.13259
更新日期:2017-11-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Port-wine stains, also known as capillary malformations, are due to dermal vascular ectasia and dilation and are most commonly congenital; however, acquired port-wine stains (APWS) developing later in life have been noted in the literature, most commonly in the context of trauma. METHODS/RESULTS:...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/pde.14019
更新日期:2020-01-01 00:00:00
abstract::Two unrelated Hispanic females, ages 4 and 3 years, respectively, each presented with a solitary patch of excessive terminal hair growth in the midline of the neck. This rare form of congenital localized hypertrichosis, known as anterior cervical hypertrichosis, is reported here as an isolated defect with no other und...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/j.1525-1470.2010.01269.x
更新日期:2010-09-01 00:00:00
abstract::Eruptive vellus hair cysts are benign lesions that can be difficult to distinguish from other skin conditions, including molluscum contagiosum and acne vulgaris. Diagnosis can be corroborated with histopathology. We emphasize differing dermoscopy features to help distinguish eruptive vellus hair cysts from molluscum c...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/j.1525-1470.2012.01771.x
更新日期:2012-11-01 00:00:00
abstract::A 17-year-old woman with Cornelia de Lange syndrome had asymptomatic skin lesions since the age of 4 years. These were multiple, follicular, horny papules, present on both cheeks, and surrounded by erythematous skin. Similar lesions were present on the external aspect of the arms, but amidst skin of normal coloration....
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1046/j.1525-1470.2002.00003.x
更新日期:2002-01-01 00:00:00
abstract::Connective tissue nevi of collagen type are now classified in four major subtypes. In addition to the clinicopathological features of papulolinear collagenoma, which is considered as a variant of isolated collagen harmatoma, the case we present has a unique arborizing pattern. ...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/j.1525-1470.2008.00842.x
更新日期:2009-01-01 00:00:00
abstract::We describe a bullous-hemorrhagic reaction of the ear lobes in a child with nephrosis after levamisole intake. This drug is used in children as an alternative treatment of corticosteroid-responsive nephrotic syndrome. Histologic evaluation of a lesion revealed necrotizing vasculitis involving mainly the large vessels ...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/j.1525-1470.1997.tb00695.x
更新日期:1997-11-01 00:00:00
abstract::Tuberous sclerosis with macrodactyly is a very uncommon presentation. We report a 15-year-old girl with a thick, loose hyperpigmented area on the dorsum of the left hand with macrodactyly. A skin biopsy specimen from the dorsum of the left hand revealed dense collagenization in the dermis. Radiographs showed marked ir...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1046/j.1525-1470.2000.01821.x
更新日期:2000-11-01 00:00:00
abstract::PHACE syndrome is characterized by posterior fossa malformations (P), large facial hemangiomas (H), arterial anomalies (A), cardiac anomalies or coarctation of aorta (C), and eye anomalies (E) and has striking female predominance. Endocrine abnormalities have recently been described in these patients, involving the th...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/j.1525-1470.2011.01540.x
更新日期:2012-05-01 00:00:00
abstract::We describe a new case of a rare syndrome characterized by ocular abnormalities and pathognomonic linear skin defects. This syndrome is the result of an unbalanced translocation resulting in a deletion of the distal end of the short arm of the X chromosome. We report the thirteenth case and review the clinical and cyt...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/j.1525-1470.1997.tb00422.x
更新日期:1997-01-01 00:00:00
abstract::In order to assess the clinical characteristics and impact of group A streptococcal infection in children with atopic dermatitis, a retrospective review was performed in children diagnosed with atopic dermatitis who had a skin culture. Culture results and clinical characteristics of those with group A streptococcus we...
journal_title:Pediatric dermatology
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1525-1470.2010.01377.x
更新日期:2011-05-01 00:00:00
abstract::Two hundred forty-seven healthy newborns were investigated in a prospective cohort descriptive study. Information on phenotype and obstetric and parental history was collected. A positive association was found between erythema toxicum neonatorum and season of birth (spring and summer), whereas parental history of any ...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/j.1525-1470.2011.01505.x
更新日期:2012-03-01 00:00:00
abstract::Computerized tomography (CT) of the brain was performed in 10 of 11 consecutive infants with neonatal lupus erythematosus (NLE) (five boys and six girls). Ten of the 11 infants had brain neurosonography. Nine of 10 infants had abnormal CT scans. There was diffuse, markedly reduced attenuation of the cerebral white mat...
journal_title:Pediatric dermatology
pub_type: 杂志文章,评审
doi:10.1046/j.1525-1470.2003.03014.x
更新日期:2003-01-01 00:00:00