Abstract:
BACKGROUND/OBJECTIVES:Epidemiologic studies of children with alopecia areata (AA) are sparse, and there are no studies that focus on the youngest children with AA. Evaluation of the clinical presentations of AA in children <4 years of age was performed in order to identify the prognostic factors for disease progression. METHODS:We performed a retrospective chart review of 125 pediatric patients seen at the Children's Hospital of Philadelphia with an initial presentation of AA under the age of 4. Disease severity was measured using the Severity of Alopecia Tool (SALT) score at initial presentation, 3-6 months later, 1 year later, and then at 2 years. RESULTS:Initial presentation was most common between ages 2 and 4 years. Most children had mild disease severity and continued mild disease over the next 2 years. Children with more than 50% of hair loss at presentation were much more likely to have worsening SALT scores over time and remain more severe. Approximately 41% had concomitant atopic dermatitis, 28% had a family member with AA, and 27% had a first-degree family member with one or more autoimmune diseases. CONCLUSIONS:In a diverse patient population, most children with AA even when presenting under age 4 have mild disease (<50% hair loss on scalp). Those who present with more severe disease are more likely to worsen or remain severe over time. These findings can aid family counseling and education.
journal_name
Pediatr Dermatoljournal_title
Pediatric dermatologyauthors
Rangu S,Rogers R,Castelo-Soccio Ldoi
10.1111/pde.13990subject
Has Abstractpub_date
2019-11-01 00:00:00pages
854-858issue
6eissn
0736-8046issn
1525-1470journal_volume
36pub_type
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