Characterization of Herpes Simplex Virus Infections Seen in the Pediatric Dermatology Office.

Abstract:

BACKGROUND/OBJECTIVES:Atypical and severe clinical manifestations of primary and recurrent herpes simplex virus (HSV) infections may present to a pediatric dermatologist for evaluation. The purpose of this study was to characterize the clinical features of the population diagnosed with HSV referred to a pediatric dermatology office. METHODS:This retrospective case series examined patients diagnosed with HSV in a pediatric dermatology practice at an academic medical center from 2005 to 2015. Characteristics of the population were collected and analyzed. RESULTS:In this study of 48 children diagnosed with HSV, 33% presented at age 2 years or younger, with approximately half having exhibited initial symptoms before 2 years of age; 39.6% of the population had six or more outbreaks per year. The outbreaks were equally divided between unifocal and multifocal presentations, with 60% of children without any labial or mucosal involvement. Suppressive treatment was initiated in 33% of patients; the average age at initiation was 6 years. CONCLUSION:Our data characterize a subset of immunocompetent young children who present to pediatric dermatologists with frequent HSV outbreaks that are often multifocal and involve cutaneous sites, with or without mucosal involvement.

journal_name

Pediatr Dermatol

journal_title

Pediatric dermatology

authors

Gittler JK,Mu EW,Orlow SJ

doi

10.1111/pde.13190

subject

Has Abstract

pub_date

2017-07-01 00:00:00

pages

446-449

issue

4

eissn

0736-8046

issn

1525-1470

journal_volume

34

pub_type

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