Benign cephalic histiocytosis with diabetes insipidus.

Abstract:

:Benign cephalic histiocytosis is a rare skin condition consisting of small tan papules on the face and upper trunk that is believed not to be associated with internal organ involvement. The infiltrating histiocytes are not Langerhans' cells (LCs). We report a 5-year-old girl who presented with diabetes insipidus 1 year after developing multiple small brown asymptomatic skin papules. Histologic examination revealed a non-LC histiocytic proliferation in the dermis without epidermal invasion. She had infiltration of the pituitary stalk on brain imaging. Diabetes insipidus has heretofore been associated with LC histiocytosis and xanthoma disseminatum but not benign cephalic histiocytosis.

journal_name

Pediatr Dermatol

journal_title

Pediatric dermatology

authors

Weston WL,Travers SH,Mierau GW,Heasley D,Fitzpatrick J

doi

10.1046/j.1525-1470.2000.01779.x

subject

Has Abstract

pub_date

2000-07-01 00:00:00

pages

296-8

issue

4

eissn

0736-8046

issn

1525-1470

pii

pde1779

journal_volume

17

pub_type

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