Abstract:
:Benign cephalic histiocytosis is a rare skin condition consisting of small tan papules on the face and upper trunk that is believed not to be associated with internal organ involvement. The infiltrating histiocytes are not Langerhans' cells (LCs). We report a 5-year-old girl who presented with diabetes insipidus 1 year after developing multiple small brown asymptomatic skin papules. Histologic examination revealed a non-LC histiocytic proliferation in the dermis without epidermal invasion. She had infiltration of the pituitary stalk on brain imaging. Diabetes insipidus has heretofore been associated with LC histiocytosis and xanthoma disseminatum but not benign cephalic histiocytosis.
journal_name
Pediatr Dermatoljournal_title
Pediatric dermatologyauthors
Weston WL,Travers SH,Mierau GW,Heasley D,Fitzpatrick Jdoi
10.1046/j.1525-1470.2000.01779.xsubject
Has Abstractpub_date
2000-07-01 00:00:00pages
296-8issue
4eissn
0736-8046issn
1525-1470pii
pde1779journal_volume
17pub_type
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