Novel KIT mutation presenting as marked lentiginosis.

Abstract:

:Although lentigines are usually benign, they can be associated with a number of genetic syndromes in which neoplasms and other multi-system pathological processes occur. Here, we report the case of a 6-year-old girl who presented with atypical lentiginosis and hyperpigmentation caused by a de novo genetic variant in the KIT gene.

journal_name

Pediatr Dermatol

journal_title

Pediatric dermatology

authors

Tran AK,Pearce A,López-Sánchez M,Pérez-Jurado LA,Barnett C

doi

10.1111/pde.13952

subject

Has Abstract

pub_date

2019-11-01 00:00:00

pages

922-925

issue

6

eissn

0736-8046

issn

1525-1470

journal_volume

36

pub_type

  • Acanthosis nigricans: a common finding in overweight youth.

    abstract::We evaluated the prevalence of acanthosis nigricans among urban youth. Youth (7-17 years) at nine pediatric practices completed surveys on demographics and family history of diabetes and had weight and height measured. Acanthosis nigricans was scored and digital photography of the neck performed. A total of 618 youth ...

    journal_title:Pediatric dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1525-1470.2007.00547.x

    authors: Brickman WJ,Binns HJ,Jovanovic BD,Kolesky S,Mancini AJ,Metzger BE,Pediatric Practice Research Group.

    更新日期:2007-11-01 00:00:00

  • Radiation Recall Dermatitis Secondary to Dactinomycin.

    abstract::Radiation recall dermatitis (RRD) is an uncommon reaction typically triggered by the use of chemotherapeutic agents in the months after treatment with radiation therapy. It usually presents as dermatitis in the irradiated field with prominent intertriginous involvement, and because internal involvement occurs in up to...

    journal_title:Pediatric dermatology

    pub_type: 杂志文章

    doi:10.1111/pde.12903

    authors: Prindaville B,Horii KA,Canty KM

    更新日期:2016-09-01 00:00:00

  • Scalp infestation by Phthirus pubis in a 6-week-old infant.

    abstract::This case report describes a 6-week-old infant with a Phthirus pubis infestation of the scalp. It is believed this patient is the first reported case in this age group. Treatment is discussed, as are the family dynamics that put this infant at risk. The authors address the possible association between infestation and ...

    journal_title:Pediatric dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1525-1470.1990.tb00284.x

    authors: Silburt BS,Parsons WL

    更新日期:1990-09-01 00:00:00

  • Case report: vulvar lichen sclerosus in a premenarchal girl with a complicated biopsy.

    abstract::Lichen sclerosus is a T-lymphocyte mediated chronic cutaneous disorder with predilection for the vulva. In prepubertal girls, lichen sclerosus presents as vulvar discomfort, pruritus, bruising/bleeding, discharge, dysuria, or painful defecation. Diagnosis and treatment of lichen sclerosus is of utmost importance in th...

    journal_title:Pediatric dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1525-1470.2009.00922.x

    authors: Yousefi M,Pride H,Elston D

    更新日期:2009-05-01 00:00:00

  • Polycystic Ovary Syndrome: Special Diagnostic and Therapeutic Considerations for Children.

    abstract::Polycystic ovary syndrome (PCOS) is an endocrine syndrome with variable phenotypic expression and important systemic associations and sequelae, including obesity, insulin resistance, infertility, risk of endometrial cancer, and possible risk of cardiovascular events. PCOS is recognized as a condition influenced by gen...

    journal_title:Pediatric dermatology

    pub_type: 杂志文章,评审

    doi:10.1111/pde.12566

    authors: Kamangar F,Okhovat JP,Schmidt T,Beshay A,Pasch L,Cedars MI,Huddleston H,Shinkai K

    更新日期:2015-09-01 00:00:00

  • Imatinib mesylate-induced pseudoporphyria in two children.

    abstract::Imatinib mesylate was the first of several tyrosine kinase inhibitors approved for use in the treatment of a number of human cancers. Adverse cutaneous reactions to imatinib are common. Pseudoporphyria has been infrequently reported in adults undergoing imatinib therapy for chronic myeloid leukemia. We present two chi...

    journal_title:Pediatric dermatology

    pub_type: 杂志文章

    doi:10.1111/pde.12380

    authors: Mahon C,Purvis D,Laughton S,Bradbeer P,Teague L

    更新日期:2014-09-01 00:00:00

  • Tinea capitis in a newborn caused by two organisms.

    abstract::Tinea capitis is a common infection of childhood. There have been several reports of tinea capitis in newborns. Our patient presented at 19 days of age to the emergency room with a scalp lesion of 5 days duration. The fungal culture grew both Trichophyton rubrum and Trichophyton mentagrophytes. The patient was success...

    journal_title:Pediatric dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1525-1470.1997.tb00245.x

    authors: Ungar SL,Laude TA

    更新日期:1997-05-01 00:00:00

  • The benefits of sunflower oleodistillate (SOD) in pediatric dermatology.

    abstract::For millennia, sunflower seed oil has been used in folk medicine for both skin care and the treatment of skin disorders. In its natural state, the oil contains high levels of essential fatty acids, particularly linoleic acid, which has skin barrier-enhancing properties. A sunflower oleodistillate (SOD), which is produ...

    journal_title:Pediatric dermatology

    pub_type: 杂志文章,评审

    doi:10.1111/j.1525-1470.2009.01042.x

    authors: Eichenfield LF,McCollum A,Msika P

    更新日期:2009-11-01 00:00:00

  • Varied Presentations of Pediatric Lipoblastoma: Case Series and Review of the Literature.

    abstract::Lipoblastoma is a rare neoplasm of embryonal adipose tissue most often encountered on the trunk and extremities of children. It commonly presents as a painless subcutaneous soft tissue mass, but there are other unique clinical presentations that are important to recognize. The differential is broad and includes sarcom...

    journal_title:Pediatric dermatology

    pub_type: 杂志文章,评审

    doi:10.1111/pde.13071

    authors: Shen LY,Amin SM,Chamlin SL,Mancini AJ

    更新日期:2017-03-01 00:00:00

  • Osteoma cutis as a presenting sign of pseudohypoparathyroidism.

    abstract::Four unrelated children with osteoma cutis and Albright hereditary osteodystrophy (pseudohypoparathyroidism and pseudopseudohypoparathyroidism) are described. All four patients were normocalcemic when they were first seen with cutaneous ossification. A diagnosis of Albright hereditary osteodystrophy was established on...

    journal_title:Pediatric dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1525-1470.1992.tb00318.x

    authors: Prendiville JS,Lucky AW,Mallory SB,Mughal Z,Mimouni F,Langman CB

    更新日期:1992-03-01 00:00:00

  • Reversible neurotoxicity after an overdose of topical lindane in an infant.

    abstract::Lindane (gamma benzene hexachloride) is a widely prescribed topical scabicide because of its efficacy and cost-effectiveness. Although toxicity from a single proper application of lindane is generally not observed, the hazards of repeated applications, industrial exposure, and accidental ingestion have been well docum...

    journal_title:Pediatric dermatology

    pub_type: 杂志文章

    doi:10.1111/j.0736-8046.2004.21515.x

    authors: Bhalla M,Thami GP

    更新日期:2004-09-01 00:00:00

  • Disseminated bullous impetigo and atopic dermatitis: Case series and literature review.

    abstract:BACKGROUND:Bullous impetigo (BI) is a common skin infection of early childhood, resulting from desmoglein-1 cleavage by Staphylococcus aureus exfoliative toxins. Due to compromised barrier function and immune dysregulation, children with atopic dermatitis (AD) are at increased risk of cutaneous infections, yet no liter...

    journal_title:Pediatric dermatology

    pub_type: 杂志文章,评审

    doi:10.1111/pde.14032

    authors: Mannschreck D,Feig J,Selph J,Cohen B

    更新日期:2020-01-01 00:00:00

  • Neonatal skin care: Developments in care to maintain neonatal barrier function and prevention of diaper dermatitis.

    abstract:BACKGROUND:Understanding the importance of the barrier function of the skin of preterm and term neonates is crucial in effective neonatal skin and diaper care. This literature search aimed to review the development of different practices in neonatal care to maintain skin barrier function, in turn preventing diaper derm...

    journal_title:Pediatric dermatology

    pub_type: 杂志文章,评审

    doi:10.1111/pde.13714

    authors: Burdall O,Willgress L,Goad N

    更新日期:2019-01-01 00:00:00

  • Use of self-adherent silicone sheets in a pediatric burn patient: A case report and instructions for use.

    abstract::Burns and scalds are relatively common injuries in children. Formation of hypertrophic scars or keloids is feared complications. A 2-year-old girl who spilled a cup of hot coffee onto herself developed widespread hypertrophic scars and beginning keloids on her upper chest, despite application of pressure garments and ...

    journal_title:Pediatric dermatology

    pub_type: 杂志文章

    doi:10.1111/pde.14017

    authors: Eisendle K,Pichler M,De Luca J,Thuile T

    更新日期:2020-01-01 00:00:00

  • Poikiloderma with neutropenia: report of three cases including one with calcinosis cutis.

    abstract::Poikiloderma with neutropenia (PN), Clericuzio type (OMIM #604173) is a new, unique genodermatosis first described by Clericuzio et al (Am J Med Genet A, 2011, 155, 337) in Navajo Indian population. This disease is characterized by poikiloderma that usually develops in the first year of life and is associated with nai...

    journal_title:Pediatric dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1525-1470.2011.01513.x

    authors: Chantorn R,Shwayder T

    更新日期:2012-07-01 00:00:00

  • Isotretinoin-induced acne fulminans without systemic symptoms with concurrent exuberant granulation tissue.

    abstract::Acne fulminans is a severe form of acne characterized by painful, inflammatory nodules that progress into ulcers and concurrent systemic symptoms. Treatment of acne with isotretinoin can precipitate a syndrome called isotretinoin-induced acne fulminans without systemic symptoms. An exuberant granulation tissue respons...

    journal_title:Pediatric dermatology

    pub_type: 杂志文章

    doi:10.1111/pde.13389

    authors: Li AW,Antaya RJ

    更新日期:2018-03-01 00:00:00

  • Practical application of the new classification scheme for congenital melanocytic nevi.

    abstract::A new consensus-based classification of congenital melanocytic nevi (CMN) has recently been proposed. It includes categories for projected adult size (PAS) and location, satellite nevi counts, and morphologic characteristics (color heterogeneity, rugosity, nodularity, and hypertrichosis). The objective of the current ...

    journal_title:Pediatric dermatology

    pub_type: 指南,杂志文章

    doi:10.1111/pde.12428

    authors: Price HN,O'Haver J,Marghoob A,Badger K,Etchevers H,Krengel S

    更新日期:2015-01-01 00:00:00

  • Two cases of spontaneous stellate scars.

    abstract::Scar formation is a physiologic reaction to dermal injury. We describe a 11-year-old girl and her 15-year-old cousin, who both presented with stellate scarlike lesions primarily located on the hands. Histopathologic examination confirmed scar tissue formation. There was no history of initiating trauma or other possibl...

    journal_title:Pediatric dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1525-1470.2008.00644.x

    authors: van Montfrans C,Lagendijk J,Hayes D,Bousema M

    更新日期:2008-03-01 00:00:00

  • Lymphangioma scroti.

    abstract::Lymphangiomas are congenital malformations of the lymphatic system. We report a 10-year-old boy with lymphatic malformation of the scrotum, which presented as a multiloculated scrotal mass associated with edema of the left thigh and left cryptorchidism. Histopathologic examination showed scrotal lymphangioma cavernosu...

    journal_title:Pediatric dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1525-1470.2007.00557.x

    authors: Vikicevic J,Milobratovic D,Vukadinovic V,Golubovic Z,Krstic Z

    更新日期:2007-11-01 00:00:00

  • Acute febrile neutrophilic dermatosis (Sweet's syndrome): case report and review of the literature.

    abstract::An 8-month-old male infant had fever, polymorphonuclear leukocytosis, and tender, firm, elevated erythematous plaques on his face, trunk, and extremities. Histologic examination revealed a dense, perivascular, polymorphonuclear, inflammatory cell infiltrate with nuclear dust in the dermis and intrafollicular abscesses...

    journal_title:Pediatric dermatology

    pub_type: 杂志文章,评审

    doi:10.1111/j.1525-1470.1985.tb00484.x

    authors: Kibbi AG,Zaynoun ST,Kurban AK,Najjar SS

    更新日期:1985-11-01 00:00:00

  • Transient aquagenic palmar hyperwrinkling: the first instance reported in a young boy.

    abstract::Transient reactive papulotranslucent acrokeratoderma is a rare palmoplantar keratoderma seen predominantly in adolescent and young adult women. Clinically it is characterized by translucent white papules generally involving the palmar surfaces after exposure to water. The typical "hands-in-the-bucket" sign, which is n...

    journal_title:Pediatric dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1525-1470.2006.00168.x

    authors: Neri I,Bianchi F,Patrizi A

    更新日期:2006-01-01 00:00:00

  • Prevention of Flares in Children with Atopic Dermatitis with Regular Use of an Emollient Containing Glycerol and Paraffin: A Randomized Controlled Study.

    abstract:BACKGROUND/OBJECTIVES:Emollients are part of the standard treatment for atopic dermatitis (AD), although there is limited evidence that regular use of emollients as management therapy reduces the frequency of flares and corticosteroid consumption. The objective of this study was to evaluate the benefit of emollient use...

    journal_title:Pediatric dermatology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1111/pde.13113

    authors: Tiplica GS,Kaszuba A,Malinauskienė L,Konno P,Boralevi F,Garrigue E,Saint-Aroman M,Delarue A

    更新日期:2017-05-01 00:00:00

  • Melanocytic nevi in Turner syndrome.

    abstract::One morphologic feature of Turner syndrome is increased numbers of melanocytic nevi; however, little attention has been given to their characterization. The development of a melanoma in one of our patients with Turner syndrome prompted this study. We prospectively examined 10 patients with the disease, confirmed by ka...

    journal_title:Pediatric dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1525-1470.1994.tb00564.x

    authors: Becker B,Jospe N,Goldsmith LA

    更新日期:1994-06-01 00:00:00

  • Fatal nodular xanthomatosis in an infant.

    abstract::We describe a unique and puzzling case of a 7-month-old baby with a non-X hypertriglyceridemic histiocytoxanthomatosis. The disease was characterized by a massive nodular eruption that was clinically, histologically, and ultrastructurally consistent with juvenile xanthogranuloma, but it had a rapid, fatal evolution. ...

    journal_title:Pediatric dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1525-1470.1987.tb00787.x

    authors: Caputo R,Ermacora E,Gelmetti C,Gianni E

    更新日期:1987-11-01 00:00:00

  • Iatrogenic Skin Disorders and Related Factors in Newborn Infants.

    abstract:BACKGROUND/OBJECTIVES:Recent technological advances and diagnostic and therapeutic innovations have resulted in an impressive improvement in the survival of newborn infants requiring intensive care. Consequently, with the use of modern invasive diagnostic and therapeutic procedures, the incidence of iatrogenic events h...

    journal_title:Pediatric dermatology

    pub_type: 杂志文章

    doi:10.1111/pde.12960

    authors: Csoma ZR,Meszes A,Ábrahám R,Kemény L,Tálosi G,Doró P

    更新日期:2016-09-01 00:00:00

  • Cutaneous manifestations and massive genital involvement in Hennekam syndrome.

    abstract::We describe a 16-year-old boy with intestinal lymphangiectasia, lymphedema of the limbs and genitalia, mild mental retardation, and facial anomalies (Hennekam syndrome) and cutaneous lesions. Severe edema in the genital area created a gigantic mass that included the scrotum and penis. Numerous grouped red-violaceous p...

    journal_title:Pediatric dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1525-1470.2006.00225.x

    authors: Musumeci ML,Nasca MR,De Pasquale R,Schwartz RA,Micali G

    更新日期:2006-05-01 00:00:00

  • Xanthoma striatum palmare and biliary tract atresia: An unusual association.

    abstract::Cutaneous xanthomas develop as a result of lipid deposition in the dermis and may be a manifestation of various systemic diseases. The morphology and anatomic location of xanthomas are often a clue to the underlying cause. Xanthoma striatum palmare (XSP) is classically associated with dysbetalipoproteinemia and rarely...

    journal_title:Pediatric dermatology

    pub_type: 杂志文章

    doi:10.1111/pde.14225

    authors: Joner Mattias F,Escobar GF,Peruzzo J

    更新日期:2020-09-01 00:00:00

  • Lymphangioma circumscriptum treated with pulsed dye laser.

    abstract::Lymphangioma circumscriptum is a lymphatic malformation that involves the skin and may extend to subcutaneous tissue and muscle. Treatment of these lesions is challenging. Surgical excision may be performed but recurrence is common. Herein we report a child with a symptomatic lymphangioma circumscriptum that was treat...

    journal_title:Pediatric dermatology

    pub_type: 杂志文章

    doi:10.1046/j.1525-1470.2001.1862001.x

    authors: Lai CH,Hanson SG,Mallory SB

    更新日期:2001-11-01 00:00:00

  • Management of congenital melanocytic nevi in the plastic surgery clinic: Families' expectations and their persistent concern about malignancy.

    abstract:BACKGROUND:Children with congenital melanocytic nevi (CMN) were historically managed with surgical removal to lower the risk of malignant transformation. The evolving literature over the last decade has indicated a significantly lower risk than previously estimated. Indications for excision currently revolve around aes...

    journal_title:Pediatric dermatology

    pub_type: 杂志文章

    doi:10.1111/pde.13987

    authors: Mosa A,Ho ES,Heinelt M,Wong K,Neuhaus K

    更新日期:2019-11-01 00:00:00

  • Isolated Langerhans cell histiocytosis of the vulva in an infant.

    abstract::Langerhans cell histiocytosis affecting only the vulva of a child is very rare. We report a 1-year-old female infant with isolated Langerhans cell histiocytosis presenting as pruritic papules confined to the vulva, confirmed by histopathology with immunohistochemical staining. ...

    journal_title:Pediatric dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1525-1470.2009.01028.x

    authors: Hwang C,Kim YJ,Seo YJ,Park JK,Lee JH,Lee Y

    更新日期:2009-11-01 00:00:00