Imatinib mesylate-induced pseudoporphyria in two children.

Abstract:

:Imatinib mesylate was the first of several tyrosine kinase inhibitors approved for use in the treatment of a number of human cancers. Adverse cutaneous reactions to imatinib are common. Pseudoporphyria has been infrequently reported in adults undergoing imatinib therapy for chronic myeloid leukemia. We present two children with pseudoporphyria induced by imatinib therapy for hematologic malignancies. In view of the burgeoning use of imatinib in children, physicians should be aware that pseudoporphyria may develop as a consequence of imatinib therapy.

journal_name

Pediatr Dermatol

journal_title

Pediatric dermatology

authors

Mahon C,Purvis D,Laughton S,Bradbeer P,Teague L

doi

10.1111/pde.12380

subject

Has Abstract

pub_date

2014-09-01 00:00:00

pages

603-7

issue

5

eissn

0736-8046

issn

1525-1470

journal_volume

31

pub_type

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