Successful treatment of Darier's disease with adapalene gel.

Abstract:

:We report a 12-year-old Japanese boy with a 3-year history of skin lesions that had been unsuccessfully treated with topical steroids. We initiated two different topical treatments with adapalene gel 0.1% (Differin(®) Gel 0.1%) and high-concentration vitamin D3 (tacalcitol) ointment; the lesions treated with adapalene gel improved dramatically in the first 2 months, whereas the high-concentration vitamin D3 ointment resulted in little improvement. Topical adapalene gel 0.1% may be a promising choice as a topical treatment of Darier's disease because of its high efficiency and lack of adverse effects.

journal_name

Pediatr Dermatol

journal_title

Pediatric dermatology

authors

Abe M,Inoue C,Yokoyama Y,Ishikawa O

doi

10.1111/j.1525-1470.2009.01077.x

subject

Has Abstract

pub_date

2011-03-01 00:00:00

pages

197-8

issue

2

eissn

0736-8046

issn

1525-1470

pii

PDE1077

journal_volume

28

pub_type

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