Calcipotriene and corticosteroid combination therapy for vitiligo.


:Corticosteroids and photochemotherapy, using a combination of psoralen and ultraviolet A (PUVA) exposure, are the most widely prescribed therapies for vitiligo. These treatments are not uniformly effective and many patients have inadequate responses. Calcipotriene has been shown to be effective in adults and children with psoriasis when used as monotherapy and in combination with corticosteroids and phototherapy. We hypothesized that since the mechanisms of action for calcipotriene and corticosteroids are different, patients may develop more repigmentation with a combination of the two agents, while decreasing the side effects from both agents. Twelve patients with vitiligo (average age 13.1 years) were advised to use topical corticosteroids in the morning and topical calcipotriene in the evening. Of the 12 patients, 83% responded to therapy, with an average of 95% repigmentation by body surface area. Four of the patients who responded had previously failed trials of topical corticosteroids alone. All of the patients in this group had repigmentation. Eyelid and facial skin responded best to this therapy. None of the patients had adverse reactions to the treatment. Our results show that topical calcipotriene in combination with corticosteroids can repigment vitiligo, even in those patients who were previous topical corticosteroid failures.


Pediatr Dermatol


Pediatric dermatology


Travis LB,Silverberg NB




Has Abstract


2004-07-01 00:00:00














  • Localized linear bullous eruption of systemic lupus erythematosus in a child.

    abstract::A 9-year-old girl newly diagnosed with systemic lupus erythematosus (SLE) developed a localized linear papulovesicular eruption over the right dorsal hand and ulnar forearm. The skin findings were clinically suggestive of herpes zoster, lichen striatus, or lichen planus-lupus erythematosus overlap. However, histologic...

    journal_title:Pediatric dermatology

    pub_type: 杂志文章


    authors: Roholt NS,Lapiere JC,Wang JI,Bernstein LJ,Woodley DT,Eramo LR

    更新日期:1995-06-01 00:00:00

  • Differential diagnoses of diaper dermatitis.

    abstract::Diaper dermatitis is the most common contact eczema present in early childhood. The main cause is an irritant reaction to urine and feces, which is facilitated by the occlusive conditions under the diaper, leading to hyperhydration of the stratum corneum (diaper dermatitis). In addition, diaper pressure and friction c...

    journal_title:Pediatric dermatology

    pub_type: 杂志文章,评审


    authors: Fölster-Holst R

    更新日期:2018-03-01 00:00:00

  • Rapp-Hodgkin syndrome with pili canaliculi.

    abstract::A 20-year-old woman and her 12-year-old brother had hypohidrotic ectodermal dysplasia, cleft lip and palate, midfacial hypoplasia with narrow nose from the nasal bridge to the tip, narrow dysplastic nails, and conical teeth and hypodontia, and hypospadias and hypoplastic uvula in the boy. The woman had major underdeve...

    journal_title:Pediatric dermatology

    pub_type: 杂志文章


    authors: Camacho F,Ferrando J,Pichardo AR,Sotillo I,Jorquera E

    更新日期:1993-03-01 00:00:00

  • Recalcitrant scrofuloderma due to rib tuberculosis.

    abstract::Tuberculosis (TB) of the ribs is extremely rare and its diagnosis is often delayed due to the late appearance of radiologic signs. Although antituberculous drugs are the mainstay of treatment, surgery has a definite therapeutic role in recalcitrant or recurrent cases. A 5-year-old boy with scrofuloderma of the chest w...

    journal_title:Pediatric dermatology

    pub_type: 杂志文章


    authors: Kaur S,Thami GP,Gupta PN,Kanwar AJ

    更新日期:2003-07-01 00:00:00

  • Severity of cutaneous findings predict the presence of systemic symptoms in pediatric maculopapular cutaneous mastocytosis.

    abstract::Although the prognosis of maculopapular cutaneous mastocytosis (MPCM), also referred to as urticaria pigmentosa, is often benign, clinicians lack evidence to reliably predict those at risk of associated systemic manifestations. We sought to elucidate clinical markers of disease severity to provide better treatment and...

    journal_title:Pediatric dermatology

    pub_type: 杂志文章


    authors: Barnes M,Van L,DeLong L,Lawley LP

    更新日期:2014-05-01 00:00:00

  • Cervical occult spinal dysraphism: MRI findings and the value of a vascular birthmark.

    abstract::Spinal dysraphism is easily recognized in the overt form as a meningocele or myelomeningocele. The closed form or occult spinal dysraphism (OSD) can be overlooked. It occurs predominantly at the lumbosacral level, but OSD at the cervical level, although very rare, also occurs. The value of magnetic resonance imaging i...

    journal_title:Pediatric dermatology

    pub_type: 杂志文章


    authors: Enjolras O,Boukobza M,Jdid R

    更新日期:1995-09-01 00:00:00

  • Occlusive versus neurotoxic agents for topical treatment of head lice infestation: A systematic review and meta-analysis.

    abstract:BACKGROUND:Topical occlusive agents, such as petroleum jelly and silicone oils, kill head lice by coating and blocking its excretory system and are unlikely to induce treatment resistance. Although a popular alternative to neurotoxic pediculicides, their efficacy and safety remain unclear. METHODS:We searched CENTRAL,...

    journal_title:Pediatric dermatology

    pub_type: 杂志文章,meta分析


    authors: Flores-Genuino RNS,Gnilo CMS,Dofitas BL

    更新日期:2020-01-01 00:00:00

  • Is eczema herpeticum associated with the use of hot tubs?

    abstract::Cutaneous bacterial infections, most commonly caused by Pseudomonas aeruginosa, have been clearly linked to use of hot tubs. A 10-year-old female with atopic eczema developed eczema herpeticum after hot tub use with a friend who had "fever blisters"; herpes simplex virus was recovered from cutaneous vesicles. Since he...

    journal_title:Pediatric dermatology

    pub_type: 杂志文章


    authors: Cox GF,Levy ML,Wolf JE Jr

    更新日期:1985-07-01 00:00:00

  • Epidermolysis bullosa nevus-like lesions in a pediatric patient with pyoderma gangrenosum.

    abstract::Epidermolysis bullosa-associated nevi are recently described dysplastic nevi found in patients with epidermolysis bullosa. These lesions display clinical features of unusual nevi suggestive of malignancy but thus far cases with malignant transformation have not been reported. We describe a case of epidermolysis bullos...

    journal_title:Pediatric dermatology

    pub_type: 杂志文章


    authors: Mollet T,Henderson FW,Groben PA,Burkhart CN,Morrell DS

    更新日期:2011-01-01 00:00:00

  • Rothmund-Thomson syndrome (Thomson-type) and myelodysplasia.

    abstract::Rothmund-Thomson syndrome (RTS) is a genetic disease characterized by developmental abnormalities and poikilodermatous skin changes that appear in infancy. An association with myelodysplastic syndromes is rarely reported in RTS, even though impairment of immune function and recurrent infections are described in the li...

    journal_title:Pediatric dermatology

    pub_type: 杂志文章


    authors: Pianigiani E,De Aloe G,Andreassi A,Rubegni P,Fimiani M

    更新日期:2001-09-01 00:00:00

  • FOXN1 Duplication and Congenital Hypertrichosis.

    abstract::We report a case of congenital hypertrichosis and FOXN1 duplication. FOXN1 is a member of the forkhead box gene family, located on chromosome 17. Its function includes differentiation of epithelial cells and regulation of keratinocytes, especially hair keratins. Loss of function of these transcription factors leads to...

    journal_title:Pediatric dermatology

    pub_type: 杂志文章


    authors: Gilhooley E,Gormally S,Irvine A,Lynch SA,Collins S

    更新日期:2017-03-01 00:00:00

  • Good response to pulsed dye laser in patients with capillary malformation-arteriovenous malformation syndrome (CM-AVM).

    abstract::Capillary malformation-arteriovenous malformation syndrome (CM-AVM) is an autosomal dominant disorder caused by heterozygous mutations in RASA1 and EPHB4. Capillary stains in CM-AVM are compatible with Schöbinger's phase I AVMs. Vascular laser has been classically contraindicated for the treatment of AVMs, as there is...

    journal_title:Pediatric dermatology

    pub_type: 杂志文章


    authors: Iznardo H,Roé E,Puig L,Vikula M,López-Sánchez C,Baselga E

    更新日期:2020-03-01 00:00:00

  • Acquired ichthyosis as a manifestation of acute cutaneous graft-versus-host disease.

    abstract::Acquired ichythosis has been described in adult hematopoietic stem cell transplant recipients. While some authors have suggested the association of acquired ichythosis with cutaneous graft-versus-host disease, the evidence to support this association is rare. We describe a patient who developed enteritis secondary to ...

    journal_title:Pediatric dermatology

    pub_type: 杂志文章


    authors: Huang J,Pol-Rodriguez M,Silvers D,Garzon MC

    更新日期:2007-01-01 00:00:00

  • Comparison of disposable diapers with fluff absorbent and fluff plus absorbent polymers: effects on skin hydration, skin pH, and diaper dermatitis.

    abstract::Diaper dermatitis results from the action of a number of physical and chemical factors on the skin. While its etiology is complex, there is agreement that prolonged contact between wet diapers and the skin leading to excessive hydration of the stratum corneum and reduced barrier function is a primary factor. Recent re...

    journal_title:Pediatric dermatology

    pub_type: 临床试验,杂志文章


    authors: Davis JA,Leyden JJ,Grove GL,Raynor WJ

    更新日期:1989-06-01 00:00:00

  • Good, but Not Perfect: Parental Knowledge About Risk Factors for Skin Cancer and the Necessity of Sun Protection in Southern Germany.

    abstract::The level of knowledge and awareness of skin cancer risks in parents of young children is largely unknown. The Erlangen Kindergarten study, which enrolled 3,129 parents of 3- to 6-year-old children in southern Germany, addressed this. The population-based survey found an overall high level of knowledge about skin canc...

    journal_title:Pediatric dermatology

    pub_type: 杂志文章


    authors: Gefeller O,Uter W,Pfahlberg AB

    更新日期:2015-07-01 00:00:00

  • Drug reaction with eosinophilia and systemic symptoms in a cohort of Asian children.

    abstract:BACKGROUND/OBJECTIVES:Drug reaction with eosinophilia and systemic symptoms (DRESS) is rare but potentially fatal in children. Fever and rash, which are salient features of DRESS, may mimic other commonly encountered pediatric conditions. We profiled the DRESS cases in a tertiary children's hospital in Singapore. METH...

    journal_title:Pediatric dermatology

    pub_type: 杂志文章


    authors: Han XD,Koh MJ,Wong SMY

    更新日期:2019-05-01 00:00:00

  • Autologous graft-versus-host disease in a child with stage IV neuroblastoma.

    abstract::Graft-versus-host disease (GVHD) is an underappreciated complication of autologous hematopoietic stem cell transplantation (AHSCT) that can affect the skin, gastrointestinal tract, and liver. The development of this rare condition is probably due to an impairment of immunologic tolerance that can occur spontaneously t...

    journal_title:Pediatric dermatology

    pub_type: 杂志文章,评审


    authors: Kaffenberger J,Basak SA,Ioffreda M

    更新日期:2015-03-01 00:00:00

  • Revisiting childhood herpes zoster.

    abstract::Herpes zoster is rare in otherwise healthy children, but it is more common in association with immunosuppression. Maternal varicella infection during pregnancy and varicella occurring in the newborn represent risk factors for childhood herpes zoster. However, some controversies persist about risk factors, diagnosis, a...

    journal_title:Pediatric dermatology

    pub_type: 杂志文章


    authors: Nikkels AF,Nikkels-Tassoudji N,Piérard GE

    更新日期:2004-01-01 00:00:00

  • Melanotic neuroectodermal tumor of infancy.

    abstract::Melanotic neuroectodermal tumor of infancy (MNTI) is an uncommon lesion with remarkably consistent histopathologic features that arises primarily in the pediatric population. We describe a MNTI arising in the anterior maxilla of a 6-month-old boy. ...

    journal_title:Pediatric dermatology

    pub_type: 杂志文章


    authors: Magliocca KR,Pfeifle RM,Bhattacharyya I,Cohen DM

    更新日期:2012-09-01 00:00:00

  • Skin cancer prevention counseling and clinical practices of pediatricians.

    abstract::Little is known about pediatricians' counseling and clinical practices to reduce skin cancer risk among their patients. Thus our objectives were to characterize skin cancer preventive counseling and clinical practices in a sample of pediatricians and identify correlates of these practices. Physicians practicing genera...

    journal_title:Pediatric dermatology

    pub_type: 杂志文章


    authors: Gritz ER,Tripp MK,de Moor CA,Eicher SA,Mueller NH,Spedale JH

    更新日期:2003-01-01 00:00:00

  • Q-switched ruby laser treatment of traumatic tattooing induced by pencil point puncture in children.

    abstract::Traumatic tattoos induced by pencil point puncture in children may result in persistent disfigurement if left untreated. The Q-switched ruby laser effectively removes darkly colored cutaneous chromophores with minimal disruption of unaffected skin. We present a young patient with pencil point induced traumatic tattooi...

    journal_title:Pediatric dermatology

    pub_type: 杂志文章


    authors: Knoell KA,Schreiber AJ,Kutenplon M,Milgraum SS

    更新日期:1997-07-01 00:00:00

  • Necrobiosis lipoidica diabeticorum in children and adolescents: a clue for underlying renal and retinal disease.

    abstract::The prevalence of persistent microalbuminuria, retinopathy, and peripheral and autonomic neuropathy was assessed in 18 children and adolescents with type 1 (insulin-dependent) diabetes mellitus (IDDM) who suffered from necrobiosis lipoidica diabeticorum (NLD) and in 40 diabetics without NLD, matched for sex, age, dura...

    journal_title:Pediatric dermatology

    pub_type: 杂志文章


    authors: Verrotti A,Chiarelli F,Amerio P,Morgese G

    更新日期:1995-09-01 00:00:00

  • Fibroadipose vascular anomaly treated with sirolimus: Successful outcome in two patients.

    abstract::Fibroadipose vascular anomaly (FAVA) is a rare, complex mesenchymal malformation combining fibrofatty replacement of the affected muscles and slow-flow vascular malformation. The condition is characterized by localized swelling, severe pain, phlebectasia, and contracture of the affected limb. Treatment paradigms are n...

    journal_title:Pediatric dermatology

    pub_type: 杂志文章


    authors: Erickson J,McAuliffe W,Blennerhassett L,Halbert A

    更新日期:2017-11-01 00:00:00

  • Aromatase inhibitor-induced hair loss in two adolescents.

    abstract::Hair loss and thinning are possible complications in those undergoing endocrine therapies with aromatase inhibitors. Alopecia in pediatric patients undergoing endocrine therapy has not been previously reported. We describe two adolescents, 14 and 16 years of age, who developed androgenetic alopecia following treatment...

    journal_title:Pediatric dermatology



    authors: Perper M,Herskovitz I,Tosti A

    更新日期:2020-11-01 00:00:00

  • Use of self-adherent silicone sheets in a pediatric burn patient: A case report and instructions for use.

    abstract::Burns and scalds are relatively common injuries in children. Formation of hypertrophic scars or keloids is feared complications. A 2-year-old girl who spilled a cup of hot coffee onto herself developed widespread hypertrophic scars and beginning keloids on her upper chest, despite application of pressure garments and ...

    journal_title:Pediatric dermatology

    pub_type: 杂志文章


    authors: Eisendle K,Pichler M,De Luca J,Thuile T

    更新日期:2020-01-01 00:00:00

  • Temporal trends in mucocutaneous findings among human immunodeficiency virus 1-infected children in a population-based cohort.

    abstract::The objective of the study was to determine the prevalence of pediatric human immunodeficiency virus 1 (HIV-1) mucocutaneous manifestations in the era of highly active antiretroviral therapy (HAART). We conducted population-based, prospective, multicenter pediatric HIV-1 surveillance in 276 children with perinatally a...

    journal_title:Pediatric dermatology

    pub_type: 杂志文章,多中心研究


    authors: Sturt AS,Anglemyer A,Berk DR,Maldonado YA

    更新日期:2013-07-01 00:00:00

  • Coronary artery thickening with mucosal lesions in Henoch-Schönlein purpura.

    abstract::Henoch-Schönlein purpura (HSP) is the most common vasculitis of childhood. It is usually self-limiting and is characterized by an immune complex-mediated vasculitis associated with IgA deposition. We present an unusual case of HSP with mucosal lesions and coronary artery thickening. ...

    journal_title:Pediatric dermatology

    pub_type: 杂志文章


    authors: Veetil BM,Reed AM,Mattke AC

    更新日期:2012-05-01 00:00:00

  • Is Routine Electrocardiography Necessary Before Initiation of Propranolol for Treatment of Infantile Hemangiomas?

    abstract:BACKGROUND:In recent years propranolol has become the treatment of choice for infantile hemangiomas (IHs). There is broad variation in the approach to propranolol initiation in clinical practice. This retrospective study explored the effectiveness of routine pre-treatment ECG in screening infants being considered for s...

    journal_title:Pediatric dermatology

    pub_type: 杂志文章


    authors: Yarbrough KB,Tollefson MM,Krol AL,Leitenberger SL,Mann JA,MacArthur CJ

    更新日期:2016-11-01 00:00:00

  • Pediatric teledermatology--a survey of current use.

    abstract::Demand for pediatric dermatologic care far exceeds the supply of pediatric dermatologists. Teledermatology has been proposed as a solution to improve access to care, however, data regarding teledermatology use for pediatric patients are lacking. Surveys assessing use and experience with teledermatology were administer...

    journal_title:Pediatric dermatology

    pub_type: 杂志文章


    authors: Fieleke DR,Edison K,Dyer JA

    更新日期:2008-03-01 00:00:00

  • Eruptive juvenile xanthogranuloma associated with relapsing acute lymphoblastic leukemia.

    abstract::Juvenile xanthogranuloma is a benign, self-healing disorder with characteristic lesions mainly involving the skin. Although most patients with juvenile xanthogranuloma have only cutaneous symptoms, recent articles have documented extracutaneous manifestations: systemic involvement of many organs has been reported and ...

    journal_title:Pediatric dermatology

    pub_type: 杂志文章


    authors: Aparicio G,Mollet J,Bartralot R,Bodet D,Heras C,Bassas P,Virós A,García-Patos V

    更新日期:2008-07-01 00:00:00