Acquired ichthyosis as a manifestation of acute cutaneous graft-versus-host disease.

Abstract:

:Acquired ichythosis has been described in adult hematopoietic stem cell transplant recipients. While some authors have suggested the association of acquired ichythosis with cutaneous graft-versus-host disease, the evidence to support this association is rare. We describe a patient who developed enteritis secondary to acute graft-versus-host disease and had concomitant ichthyosiform lesions. Several months later, he was diagnosed with cutaneous graft-versus-host disease. This patient is presented to suggest that acquired ichthyosis is an underrecognized manifestation of acute cutaneous graft-versus-host disease. Given the important prognostic implications of this diagnosis, we recommend a low threshold for performing a skin biopsy to rule out GVHD in the appropriate clinical setting.

journal_name

Pediatr Dermatol

journal_title

Pediatric dermatology

authors

Huang J,Pol-Rodriguez M,Silvers D,Garzon MC

doi

10.1111/j.1525-1470.2007.00333.x

subject

Has Abstract

pub_date

2007-01-01 00:00:00

pages

49-52

issue

1

eissn

0736-8046

issn

1525-1470

pii

PDE333

journal_volume

24

pub_type

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