Melanocytic nevi in Turner syndrome.

Abstract:

:One morphologic feature of Turner syndrome is increased numbers of melanocytic nevi; however, little attention has been given to their characterization. The development of a melanoma in one of our patients with Turner syndrome prompted this study. We prospectively examined 10 patients with the disease, confirmed by karyotype. All patients underwent full body skin examination noting the number, size, distribution, and degree of clinical atypia of melanocytic nevi. Representative and unusual lesions were photographed. An average of 115 nevi were seen, with the majority measuring 1 to 5 mm. Most were located on the back and extremities. Clinical atypia was uncommon. Our patients had larger numbers of benign-appearing nevi than the general population. Large numbers of melanocytic nevi is a risk factor for melanoma, suggesting that these patients have an increase in one risk factor. Longitudinal studies are indicated to clarify this issue; nevertheless, we recommend periodic skin examinations and the regular use of sunscreens for individuals with Turner syndrome.

journal_name

Pediatr Dermatol

journal_title

Pediatric dermatology

authors

Becker B,Jospe N,Goldsmith LA

doi

10.1111/j.1525-1470.1994.tb00564.x

subject

Has Abstract

pub_date

1994-06-01 00:00:00

pages

120-4

issue

2

eissn

0736-8046

issn

1525-1470

journal_volume

11

pub_type

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