Abstract:
:We present the case of an 8-year-old girl who presented with distal extremity necrosis of the hands, feet, nose, and ears as an acute manifestation of cutaneous polyarteritis nodosa (CPAN). She was emergently managed with intravenous steroids, nifedipine, sildenafil, pentoxifylline, nitroglycerin paste, aspirin, low-molecular-weight heparin, and intravenous gamma globulin. The necrosis was controlled, and reperfusion was attained to salvage the extremities. It is important for clinicians to be aware that acute distal extremity necrosis can be a manifestation of CPAN in children. Etiology is often not clear on presentation, but once infection is excluded, acute management with systemic steroids and systemic vasodilators is indicated regardless of the cause. Iloprost and bosentan may represent options for adjunctive vasodilators. More studies are needed to create guidelines for the acute and long-term management of these children. Close follow-up of children with CPAN, especially with a history of vaso-occlusive symptoms, is important to allow prompt intervention in the event of distal extremity infarction.
journal_name
Pediatr Dermatoljournal_title
Pediatric dermatologyauthors
Williams VL,Guirola R,Flemming K,Modi GM,Rosales C,DeGuzman MMdoi
10.1111/j.1525-1470.2011.01515.xsubject
Has Abstractpub_date
2012-07-01 00:00:00pages
473-8issue
4eissn
0736-8046issn
1525-1470journal_volume
29pub_type
杂志文章,评审abstract::A new consensus-based classification of congenital melanocytic nevi (CMN) has recently been proposed. It includes categories for projected adult size (PAS) and location, satellite nevi counts, and morphologic characteristics (color heterogeneity, rugosity, nodularity, and hypertrichosis). The objective of the current ...
journal_title:Pediatric dermatology
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abstract::Childhood lichen sclerosus (LS) is a rare and often misdiagnosed inflammatory dermatitis with an unpredictable course. The complications of LS are architectural changes of the vulva; malignant transformation is possible. The objective of our study was to define the background and the long-term course of childhood LS. ...
journal_title:Pediatric dermatology
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abstract::Harlequin ichthyosis (HI) is a rare autosomal recessive disorder of cornification in which children are born with an extremely thick stratum corneum that becomes a restrictive circumferential encasement around the orifices, limbs, chest, and abdomen, resulting in limb contractures. We present a neonate diagnosed in ut...
journal_title:Pediatric dermatology
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journal_title:Pediatric dermatology
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doi:10.1046/j.1525-1470.2003.20307.x
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journal_title:Pediatric dermatology
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journal_title:Pediatric dermatology
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doi:10.1046/j.1525-1470.1999.00081.x
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journal_title:Pediatric dermatology
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journal_title:Pediatric dermatology
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journal_title:Pediatric dermatology
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journal_title:Pediatric dermatology
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doi:10.1111/pde.13956
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journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/j.1525-1470.2007.00333.x
更新日期:2007-01-01 00:00:00
abstract:OBJECTIVES:To identify clinical factors associated with complications of periocular infantile hemangioma (IH) and monitor improvement in complication rates post-treatment. METHODS:Retrospective cohort study. Eighty-nine patients diagnosed with periocular IH at a pediatric dermatology clinic of a tertiary care center b...
journal_title:Pediatric dermatology
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doi:10.1111/pde.13925
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journal_title:Pediatric dermatology
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journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/pde.12693
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abstract::Montelukast was effective in treating refractory abdominal and urinary symptoms in a child with systemic mastocytosis. ...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/j.1525-1470.2011.01576.x
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abstract::We describe deep granuloma annulare (DGA) of the forehead mimicking inflamed cysts. Reactive inflammation and sterile purulent drainage may be an underrecognized feature of DGA. ...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/pde.13137
更新日期:2017-07-01 00:00:00
abstract::The objective of the study was to determine the prevalence of pediatric human immunodeficiency virus 1 (HIV-1) mucocutaneous manifestations in the era of highly active antiretroviral therapy (HAART). We conducted population-based, prospective, multicenter pediatric HIV-1 surveillance in 276 children with perinatally a...
journal_title:Pediatric dermatology
pub_type: 杂志文章,多中心研究
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journal_title:Pediatric dermatology
pub_type: 杂志文章
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journal_title:Pediatric dermatology
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journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/j.1525-1470.2009.01028.x
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journal_title:Pediatric dermatology
pub_type: 杂志文章
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更新日期:2020-01-01 00:00:00
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journal_title:Pediatric dermatology
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journal_title:Pediatric dermatology
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doi:10.1111/pde.14383
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journal_title:Pediatric dermatology
pub_type: 杂志文章
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journal_title:Pediatric dermatology
pub_type: 杂志文章
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journal_title:Pediatric dermatology
pub_type: 杂志文章
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abstract::We report the exceptional case of 11-year-old identical male twins who both developed discoid lupus erythematosus lesions. Although systemic lupus erythematosus has often been reported in identical twins, discoid lupus erythematosus has only occasionally been described, with only one other case in twin children, as fa...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/j.1525-1470.2008.00794.x
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