Abstract:
:Menkes's syndrome (trichopoliodystrophy) is an x-linked, recessive genodermatosis characterized by hair defects, severe retardation, convulsions, progressive neurologic deterioration, and early death. Recent studies in copper metabolism suggest that Menkes's syndrome may be a storage disease in which copper is irreversibly trapped in some tissues by metallothionein, a heavy-metal-binding protein. This then gives rise to a deficiency elsewhere, particularly in the brain, causing irreversible damage in the fetus. We present a patient with Menkes's syndrome and review the clinical and metabolic aspects of this disease.
journal_name
Pediatr Dermatoljournal_title
Pediatric dermatologyauthors
Maddox JL Jr,Odom RB,Goette DKdoi
10.1111/j.1525-1470.1984.tb01135.xsubject
Has Abstractpub_date
1984-04-01 00:00:00pages
307-11issue
4eissn
0736-8046issn
1525-1470journal_volume
1pub_type
杂志文章abstract::Ataxia telangiectasia (AT) is a rare autosomal recessive neurodegenerative disorder caused by a mutation in the ATM gene. An impaired immune response due to the gene mutation leads to an increased risk of infection and malignancy. We present a rare case of dermatofibrosarcoma protuberans arising in a patient with AT. ...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/pde.13779
更新日期:2019-05-01 00:00:00
abstract::Dyshidrotic eczema is one of the rare cutaneous adverse effects of intravenous immunoglobulin therapy, usually seen in adults. We herein report the first pediatric case of severe dyshidrotic eczema occurring after intravenous immunoglobulin therapy for Kawasaki syndrome. ...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/j.1525-1470.2011.01717.x
更新日期:2013-05-01 00:00:00
abstract::Skin and thymus were obtained from abortuses of varying ages and from neonatal autopsies to determine if S100-protein-containing dendritic cells were present. Using an unlabeled antibody peroxidase-antiperoxidase method, we could not detect these dendritic cells in epidermis prior to live birth, but did detect them at...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/j.1525-1470.1986.tb00518.x
更新日期:1986-06-01 00:00:00
abstract::Autosomal recessive congenital ichthyosis is a genetically and phenotypically heterogenous group of scaling skin disorders. We describe a patient with ARCI caused by homozygous variants in NIPAL4, in whom the dermatologic phenotype and an associated arthropathy, markedly improved with ustekinumab. ...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/pde.13995
更新日期:2019-11-01 00:00:00
abstract::Vitiligo is a common acquired progressive depigmenting condition that can have devastating psychological effects in dark-skinned patients. We performed a retrospective review of patients younger than 16 years of age with a clinical diagnosis of vitiligo treated using phototherapy at the National Skin Center, Singapore...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/pde.12506
更新日期:2015-03-01 00:00:00
abstract::Cutaneous manifestations are becoming increasingly well-documented in adults with COVID-19. There is now also a growing body of literature regarding skin involvement in children, with reports of papulovesicular, petechial and widespread macular and papular lesions, and chilblains (pernio). We describe the case of a 13...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/pde.14257
更新日期:2020-09-01 00:00:00
abstract::Triethanolamine is used as an emulsifier in many cosmetics and in topical medications, yet the occurrence of contact dermatitis to cosmetics containing triethanolamine is rare in childhood. Our case highlights how young age should not be a deterrent to investigation and demonstrates the importance of patch testing wit...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/pde.12537
更新日期:2015-05-01 00:00:00
abstract::Red-brown papules developing during the neonatal period may present a diagnostic dilemma. The Darier sign has been a reliable feature in the diagnosis of mastocytosis. However, the cutaneous infiltrate of Hashimoto-Pritzker Langerhans cell histiocytosis (LCH) may contain a large number of mast cells, leading to confus...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1046/j.1525-1470.2001.018001041.x
更新日期:2001-01-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Bullous impetigo (BI) is a common dermatologic condition, particularly in children, yet confusion regarding its diagnosis and treatment persists. This study measured pediatricians' ability to diagnose and appropriately treat BI and explored factors that might influence pediatricians' accuracy in m...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/pde.12974
更新日期:2016-11-01 00:00:00
abstract::Post-transplantation lymphoproliferative disorder (PTLD) is one of the most common de novo malignancies in patients who receive immunosuppressive therapy after solid organ transplantation. We report a case of a 5-year-old girl who presented with indurated violaceous skin nodules 3.5 years post-liver transplantation, d...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/pde.13903
更新日期:2019-09-01 00:00:00
abstract::Spinal dysraphism is easily recognized in the overt form as a meningocele or myelomeningocele. The closed form or occult spinal dysraphism (OSD) can be overlooked. It occurs predominantly at the lumbosacral level, but OSD at the cervical level, although very rare, also occurs. The value of magnetic resonance imaging i...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/j.1525-1470.1995.tb00172.x
更新日期:1995-09-01 00:00:00
abstract::Henoch-Schönlein purpura is an acute leukocytoclastic vasculitis that primarily affects children. Henoch-Schönlein purpura is often associated with an infection, and a wide variety of infectious agents have been implicated in the pathogenesis. We report a child with Henoch-Schönlein purpura associated with Helicobacte...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/j.1525-1470.2008.00786.x
更新日期:2008-11-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Despite rising skin cancer rates in children, multiple studies reveal inadequate youth sun-protective behavior (eg, sunscreen use). Using Healthy Passages data for fifth-graders, we set out to determine sunscreen adherence in these children and investigated factors related to sunscreen performance...
journal_title:Pediatric dermatology
pub_type: 杂志文章,多中心研究
doi:10.1111/pde.13550
更新日期:2018-09-01 00:00:00
abstract::Cerebriform intradermal nevus is a rare form of cutis verticis gyrata. Clinically it manifests as a scalp deformity resembling the surface of the brain, with cerebriform morphologic characteristics. Degeneration into malignant melanoma has been reported. Herein, a cerebriform intradermal nevus of the scalp in a 7-year...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/j.1525-1470.2007.00361.x
更新日期:2007-03-01 00:00:00
abstract::Rothmund-Thomson syndrome (RTS) is a rare autosomal recessive disorder that is caused by a DNA repair defect. It is characterized mainly by skin, eye, and skeletal abnormalities. Cutaneous changes appear at between 3 and 6 months of age and include poikiloderma, photosensitivity, scaling, hyperkeratosis, and disturban...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1046/j.1525-1470.2001.018003210.x
更新日期:2001-05-01 00:00:00
abstract::Lamotrigine is an anticonvulsant with a broad spectrum of activity that has been approved in the United States for use in adults with either partial or generalized seizures. This drug is being widely prescribed by pediatricians and neurologists because it is effective in children with idiopathic, resistant, generalize...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1046/j.1525-1470.1999.99014.x
更新日期:1999-01-01 00:00:00
abstract::Graft-versus-host disease (GVHD) is one of the major complications after hematopoietic stem cell transplantation and is responsible for post-therapeutic morbidity, mortality, and poor quality of life of recipients. Sclerodermatous graft-versus-host disease (sGVHD) is a rare variant of chronic GVHD characterized by dep...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/pde.12794
更新日期:2016-03-01 00:00:00
abstract::Diaper dermatitis results from the action of a number of physical and chemical factors on the skin. While its etiology is complex, there is agreement that prolonged contact between wet diapers and the skin leading to excessive hydration of the stratum corneum and reduced barrier function is a primary factor. Recent re...
journal_title:Pediatric dermatology
pub_type: 临床试验,杂志文章
doi:10.1111/j.1525-1470.1989.tb01005.x
更新日期:1989-06-01 00:00:00
abstract::Circumscribed juvenile pityriasis rubra pilaris (PRP) is an uncommon dermatosis. We describe the unusual clustering of circumscribed juvenile PRP cases in our pediatric dermatology clinic in 2011. A retrospective chart review was done of patients presenting during the summer of 2011 with classic findings of circumscri...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/pde.12260
更新日期:2014-03-01 00:00:00
abstract::We report an unusual occurrence of spontaneous pigmentary regression with a desmoplastic reaction in a neonatally eroded giant congenital melanocytic nevus. This process has been documented with photographs and skin biopsy specimens. Neonatal histology demonstrated connective tissue proliferation. Histology at age 5 y...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/j.1525-1470.2006.00311.x
更新日期:2006-11-01 00:00:00
abstract::Practice guidelines for the treatment of tinea capitis (TC) from the European Society for Pediatric Dermatology are presented. Tinea capitis always requires systemic treatment because topical antifungal agents do not penetrate the hair follicle. Topical treatment is only used as adjuvant therapy to systemic antifungal...
journal_title:Pediatric dermatology
pub_type: 杂志文章,实务指引
doi:10.1111/j.1525-1470.2010.01137.x
更新日期:2010-05-01 00:00:00
abstract::A 4-month-old infant had two 3 cm x 4 cm hemangiomatous lesions on the scalp and back, present since birth, which contained peculiar white-yellowish small nodules. Histologically the lesions proved to have a hemangiomatous (capillary-type) component together with small keratin-containing epidermal cysts (milia-like) w...
journal_title:Pediatric dermatology
pub_type: 杂志文章,评审
doi:10.1046/j.1525-1470.1998.1998015307.x
更新日期:1998-07-01 00:00:00
abstract::A 9-year-old girl with atopic dermatitis developed persistent plaques on the lips, hands, and fingers that were unresponsive to topical steroids. Her mother reported that she was "addicted" to costume jewelry and developed rashes in reaction to a number of adornments, ranging from rubber bracelets to costume metal jew...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/pde.12804
更新日期:2016-03-01 00:00:00
abstract::Many supplements and products containing botanical extracts are marketed to patients for the treatment of acne vulgaris. Additionally, increasing attention has been paid to the role of diet in acne vulgaris. Studies on this topic including pediatric patients are limited, with variable efficacy data. Despite these limi...
journal_title:Pediatric dermatology
pub_type: 杂志文章,评审
doi:10.1111/pde.13904
更新日期:2019-09-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Epidemiologic studies of children with alopecia areata (AA) are sparse, and there are no studies that focus on the youngest children with AA. Evaluation of the clinical presentations of AA in children <4 years of age was performed in order to identify the prognostic factors for disease progression...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/pde.13990
更新日期:2019-11-01 00:00:00
abstract::Normolipemic plane xanthoma normally occurs in adults. We report the atypical instance of a 9-year-old boy who developed disseminated, flat, yellow-brown plaques up to 2 to 3 cm without any complaints. The histology showed the hallmarks of xanthoma, including the presence of CD68+ foam cells and Touton giant cells. No...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/j.1525-1470.2005.22207.x
更新日期:2005-03-01 00:00:00
abstract::Alopecia areata (AA) involves the immune-related destruction of hair follicles, resulting in patches of complete hair loss, most often on the scalp. The topical sensitizer squaric acid dibutylester (SADBE) is a popular treatment option given its low side-effect profile, hair regrowth potential, and lack of cross-react...
journal_title:Pediatric dermatology
pub_type:
doi:10.1111/pde.12993
更新日期:2017-01-01 00:00:00
abstract::Imatinib mesylate was the first of several tyrosine kinase inhibitors approved for use in the treatment of a number of human cancers. Adverse cutaneous reactions to imatinib are common. Pseudoporphyria has been infrequently reported in adults undergoing imatinib therapy for chronic myeloid leukemia. We present two chi...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/pde.12380
更新日期:2014-09-01 00:00:00
abstract::Spitz nevi are benign melanocytic lesions with many histologic similarities to malignant melanoma. A case of agminated Spitz nevi on a 2-year-old boy's left cheek is reported and 41 other cases of agminated Spitz nevi are reviewed. In this case, two biopsies were performed on two different-appearing lesions and the re...
journal_title:Pediatric dermatology
pub_type: 杂志文章,评审
doi:10.1111/pde.12026
更新日期:2013-09-01 00:00:00
abstract::Trisomy 13, or Patau syndrome, is a chromosomal disorder that can occur in complete, partial, or mosaic forms. Mosaicism is observed in 6% of individuals with trisomy 13 and, in contrast to the complete form, has wide phenotypic variability, longer survival, and in some patients an unusual skin pigmentary pattern simi...
journal_title:Pediatric dermatology
pub_type: 杂志文章
doi:10.1111/pde.12339
更新日期:2014-09-01 00:00:00