Abstract:
OBJECTIVES:The purpose of our study was to determine morphological changes and bone mineral density (BMD) differences in the adult mandible of offspring exposed to high calcium, low phosphorus diets in utero until weaning age. MATERIALS AND METHODS:Time-mated FVB wild-type mice were fed normal or experimental diet during gestation and until weaning of offspring. Experimental diet contained 3-fold increase in calcium and 3-fold decrease in phosphorus compared to normal diet. Adult mandibles of offspring exposed to experimental diet were sacrificed and heads scanned using micro-computed tomography. Three-dimensional 3D geometric morphometric analysis GMA was utilized to detect morphological changes to the mandible including the condyle. RESULTS:Experimental females showed the greatest morphological differences including shortened mandibular ramus width and height, shortened mandibular body length and height, a wider but shortened condylar neck and a wider condylar head in the lateral-medial direction. Experimental male mandibles trended towards increased mandibular body height and length, opposite the changes observed in experimental female mandibles, whereas condyles were similar to that observed in experimental females. Bone mineral density (BMD) was lowered in experimental females. CONCLUSION:Increased calcium and decreased phosphorus levels led to a retrognathic mandible associated with lowered BMD in experimental females, whereas experimental showed partly opposite effects. Further studies are required to understand the mechanism underlying diet- and gender-specific differences in mandibular morphology.
journal_name
Orthod Craniofac Resjournal_title
Orthodontics & craniofacial researchauthors
Hassan MG,Vargas R,Zaher AR,Ismail HA,Lee C,Cox TC,Jheon AHdoi
10.1111/ocr.12269subject
Has Abstractpub_date
2019-05-01 00:00:00pages
113-119eissn
1601-6335issn
1601-6343journal_volume
22 Suppl 1pub_type
杂志文章abstract:OBJECTIVES:To review the historic context for digital imaging in dentistry and to outline the fundamental issues related to digital imaging modalities. CONTEXT:Digital dental X-ray images can be achieved by scanning analog film radiographs (secondary capture), with photostimulable phosphors, or using solid-state detec...
journal_title:Orthodontics & craniofacial research
pub_type: 历史文章,杂志文章
doi:10.1034/j.1600-0544.2003.231.x
更新日期:2003-01-01 00:00:00
abstract:OBJECTIVES:To study the efficacy of tenoxicam for pain control, its potential for preemptive analgesia, and its influence on the orthodontic movement of upper canine teeth. DESIGN:This was a randomized controlled double-blind cross-over study. The patients were divided into three groups. Two groups received tenoxicam ...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1601-6343.2008.01432.x
更新日期:2009-02-01 00:00:00
abstract:OBJECTIVE:An investigation to determine the changing facial appearance of identical twins. DESIGN:Clinical study. MATERIALS AND METHODS:Two Minolta Vivid 900 3D optical laser scanners were placed as a stereo pair to capture the soft tissues of a pair of identical twins. Each scan took approximately 2.5 s. The scanned...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/j.1601-6343.2005.00320.x
更新日期:2005-05-01 00:00:00
abstract:OBJECTIVES:To assess the effects of a modified alternate rapid maxillary expansion and constriction (Alt-RAMEC) protocol in combination with facemask (FM) in Class III growing patients. SETTING AND SAMPLE POPULATION:Thirty one Class III patients (17 males, 14 females) were treated with a modified Alt-RAMEC/FM protocol...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12051
更新日期:2014-11-01 00:00:00
abstract:OBJECTIVES:To explore centre-level variation in otitis media with effusion (OME), hearing loss and treatments in children in Cleft Care UK (CCUK) and to examine the association between OME, hearing loss and developmental outcomes at 5 and 7 years. SETTING AND SAMPLE POPULATION:Two hundred and sixty-eight 5-year-old Br...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12184
更新日期:2017-06-01 00:00:00
abstract::In cranial sutural samples derived from five children with premature cranial suture fusion we have performed immunostaining for the urokinase plasminogen activator (uPA) and urokinase receptor (uPAR). We have found a strong reactivity for cell- or matrix-bound uPA and uPAR in the sutural connective tissue and associat...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1034/j.1600-0544.2002.50101.x
更新日期:2002-02-01 00:00:00
abstract:OBJECTIVES:Relapse of teeth that have moved during orthodontic treatment is a major clinical issue with respect to the goals of successful treatment. Such relapse is a physiologic response of the supporting tissues to application of force, and is mainly attributed to occlusal instability and increased mechanical tensio...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/j.1601-6343.2009.01463.x
更新日期:2009-11-01 00:00:00
abstract:OBJECTIVES:To investigate the 3D morphological variations in 169 temporomandibular ioint (TMJ) condyles, using novel imaging statistical modeling approaches. SETTING AND SAMPLE POPULATION:The Department of Orthodontics and Pediatric Dentistry at the University of Michigan. Cone beam CT scans were acquired from 69 subj...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12070
更新日期:2015-04-01 00:00:00
abstract:UNLABELLED:AUTHOR: Shen G Objective -This review was compiled to explore the role of type X collagen in growth, development and remodeling of articular cartilage by elucidating the linkage between the synthesis of this protein and the phenotypic changes in chondrogenesis and the onset of endochondral ossification. DES...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章,评审
doi:10.1111/j.1601-6343.2004.00308.x
更新日期:2005-02-01 00:00:00
abstract:OBJECTIVE:This investigation evaluates the evidence of case-based reasoning (CBR) in providing additional information on the prediction of future Class III craniofacial growth. SETTINGS AND SAMPLE POPULATION:The craniofacial characteristics of 104 untreated Class III subjects (7-17 years of age), monitored with two la...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12466
更新日期:2021-01-08 00:00:00
abstract:OBJECTIVES:Literature is poor of data about the occlusion in children affected by neurofibromatosis type 1 (NF1). This case-control study investigated the occlusal traits in a group of children with NF1. SETTING AND SAMPLE POPULATION:A hundred and fifteen children with NF1 were enrolled; non-NF1 controls were sequenti...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12108
更新日期:2016-02-01 00:00:00
abstract:OBJECTIVES:While some eruption disorders occur as part of a medical syndrome, primary failure of eruption (PFE) - defined as a localized failure of secondary tooth eruption - exists without systemic involvement. Recent studies support that heredity may play an important role in the pathogenesis of PFE. The objective of...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/j.1601-6343.2009.01440.x
更新日期:2009-05-01 00:00:00
abstract::The aim of this review was to systematically appraise the evidence on aligner mechanics and forces and moments generated across difference types of aligners. In vitro- laboratory studies for model simulated tooth movement with aligners. Database searches within Medline via Pubmed, Cochrane Central Register of Controll...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章,meta分析,评审
doi:10.1111/ocr.12333
更新日期:2019-11-01 00:00:00
abstract::The mental health of children, adolescents, and adults with orofacial clefts has been studied extensively. Outcomes of interest have included parental adaptation, parent-child attachment, child development, intellectual and academic outcomes, behavioral adaptation, and quality of life. The literature sheds light on me...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章,评审
doi:10.1111/j.1601-6343.2007.00394.x
更新日期:2007-08-01 00:00:00
abstract:OBJECTIVE:The role of oestrogen in craniofacial growth still remains unclear. Therefore, the present study aimed to assess the effect of oestrogen deficiency on maxilla and mandible dimensions. SETTING AND SAMPLE POPULATION:The study was conducted at the Department of Pediatric Dentistry at the School of Dentistry of ...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12376
更新日期:2020-08-01 00:00:00
abstract:OBJECTIVES:Three-dimensional evaluation of skeletal mandibular changes following Herbst appliance treatment. SETTING AND SAMPLE POPULATION:Retrospective case-control study, based on a sample size calculation. Twenty-five pubertal patients treated with Herbst appliance (HAG), and 25 matched Class II patients who receiv...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12154
更新日期:2017-05-01 00:00:00
abstract:OBJECTIVES:This study sought to investigate the three-dimensional (3D) changes in anteroposterior, vertical and mediolateral positions and orientations of the mandibular condyle as well as joint space parameters following maxillary first premolar extraction and incisor retraction in skeletal Class II patients. SETTING...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12141
更新日期:2017-05-01 00:00:00
abstract::The objective of the study was to provide a comprehensive review of the literature describing research done on the stability, adaptation and growth of craniofacial structures following distraction osteogenesis (DO). The design of the study was a literature review of clinical and experimental studies using electronic s...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章,评审
doi:10.1111/j.1601-6343.2009.01452.x
更新日期:2009-08-01 00:00:00
abstract:OBJECTIVE:To investigate the effect of lithium on alveolar bone formation during orthodontic retention in rats. MATERIALS AND METHODS:After 2 weeks of orthodontic tooth movement (OTM), 42 8-week-old male Wistar rats were randomly divided into two orthodontic retention groups: one without (control) and the other with L...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12190
更新日期:2017-08-01 00:00:00
abstract:OBJECTIVES:Bone repair strategies continue to be developed for alternatives to autografting, allogeneic implants of banked bone, and other bone substitutes. Efforts have included the delivery of potent growth and/or differentiation factors and the use of gene therapy. For bone regeneration, gene therapy is the delivery...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/j.1601-6343.2005.00332.x
更新日期:2005-08-01 00:00:00
abstract:PURPOSE:This paper describes the use of adult facial template in gender-specific facial analysis. SUBJECTS AND METHODS:Eighty adults, mean age 24.5, were selected for the study. Laser-scanned images of the subjects were obtained under a reproducible and controlled environment with two Minolta Vivid 900 (Osaka, Japan) ...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/j.1601-6343.2006.00359.x
更新日期:2006-02-01 00:00:00
abstract:OBJECTIVES:To evaluate root surface changes and resorption following toothborne rapid maxillary expansion (RME) using cone beam computed tomography (CBCT). SETTING AND SAMPLE POPULATION:The Department of Orthodontics at The University of Texas Health Science Center. Twenty-four consecutively treated patients (mean age...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12069
更新日期:2015-04-01 00:00:00
abstract:OBJECTIVES:To study treatment-related factors for external root resorption during orthodontic tooth movement. DESIGN:An experimental animal study. SETTING AND SAMPLE POPULATION:Department of Orthodontics and Oral Biology, University Medical Centre Nijmegen, The Netherlands. Twenty-four young adult beagle dogs. EXPER...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/j.1601-6343.2004.00283.x
更新日期:2004-05-01 00:00:00
abstract:OBJECTIVES:The purpose of this study was to investigate the effects of reduced masticatory function on midline suture growth and morphology in growing pigs. SETTING AND SAMPLE POPULATION:The sample was 20 pigs separated into two dietary groups and raised at the Department of Anthropology, Harvard University. Midline s...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/j.1601-6343.2010.01483.x
更新日期:2010-05-01 00:00:00
abstract::We have developed a cone beam X-ray computed tomography (CT) system to make more accurate three-dimensional (3-D) images for diagnosis of dento-maxillofacial region. The developed system has sufficient spatial resolution, resolution of 3-D images and image distortion for diagnosis of dentomaxillofacial region. ...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1034/j.1600-0544.2003.249.x
更新日期:2003-01-01 00:00:00
abstract:OBJECTIVES:To determine whether the use of chewing gum reduced the impact and pain of fixed orthodontic appliances. SETTING AND SAMPLE POPULATION:The Orthodontic Department of the Charles Clifford Dental Hospital, Sheffield, UK. Fifty-seven patients aged 18 years or younger and who were about to start fixed orthodonti...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1601-6343.2012.01546.x
更新日期:2012-08-01 00:00:00
abstract:OBJECTIVES:To develop a clinical practice guideline (CPG) for orthodontic retention (OR). MATERIALS AND METHODS:The CPG was developed according to the AGREE II instrument and EBRO (Dutch methodology for evidence-based guideline development). Reporting was done according the RIGHT statement. A Task Force developed clin...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章,评审
doi:10.1111/ocr.12302
更新日期:2019-05-01 00:00:00
abstract:OBJECTIVE:To clarify the correlation between variations in maximum occlusal force and the maxillofacial skeletal pattern in subjects with malocclusion using a compact device. DESIGN:Three hundred and fifty patients (150 males 200 females) with malocclusion were included. The male and female subjects were divided into ...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/j.1601-6343.2007.00405.x
更新日期:2007-11-01 00:00:00
abstract:OBJECTIVES:Basic research concerning craniofacial development presently runs along two pathways, namely the molecular and the morphometric. This gap needs to be bridged. DESIGN:Using histological serial sections of human fetuses computer-aided three-dimensional reconstructions were made (Software Analysis, SIS) with s...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1034/j.1600-0544.2003.240.x
更新日期:2003-01-01 00:00:00
abstract:OBJECTIVE:The present study aimed to analyse palatal changes due to rapid maxillary expansion (RME) by using modern geometric morphometric analysis (GMA) on 3D models. SETTINGS AND SAMPLE POPULATION:Forty children with posterior crossbite and maxillary deficiency were selected for this study. Twenty children were trea...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12387
更新日期:2020-11-01 00:00:00