Platelet endothelial aggregation receptor-1 regulates bovine muscle satellite cell migration and differentiation via integrin beta-1 and focal adhesion kinase.

abstract：:When trophoblasts migrate and invade in vivo, they do so by interacting with a range of other cell types, extracellular matrix proteins, chemotactic factors and physical forces such as fluid shear stress. These factors combine to influence overall trophoblast migration and invasion into the decidua, which in turn dete...

journal_title：Cell adhesion & migration

authors： James J,Tun W,Clark A

更新日期：2016-03-03 00:00:00

abstract：:Discovered decades ago, extracellular vesicles (EVs) emerge as dedicated organelles, able to deliver protected, specific cellular cues throughout the organism. While virtually every cell can release EVs, cancer cells co-opted this feature and efficiently unleashed them both in the tumor microenvironment and toward hea...

journal_title：Cell adhesion & migration

authors： André-Grégoire G,Gavard J

更新日期：2017-03-04 00:00:00

abstract：:An expanding body of evidence demonstrates that cells undergoing apoptosis send out a selection of molecular navigational signals including proteins, lipids and nucleotides that serve to recruit phagocytes to the dying targets which are subsequently engulfed and removed. This homeostatic process is essentially non-phl...

journal_title：Cell adhesion & migration

authors： Gregory CD,Rossi AG,Bournazou I,Zhuang L,Willems JJ

更新日期：2011-07-01 00:00:00

abstract：:Monocyte-extracellular matrix interactions have been implicated in atherosclerosis pathophysiology. Laminin, the main basement membrane protein contains cell binding domains that can be cryptic, presented only after protein modification. In the present study we evaluated monocyte attachment to laminin-1 in the presenc...

journal_title：Cell adhesion & migration

authors： Kostidou E,Trachana V,Topouridou K,Paletas K,Tsapas A,Kaloyianni M,Koliakos G

更新日期：2009-04-01 00:00:00

abstract：:It has long been thought that the same molecules guide both trunk neural crest cells and motor axons as these cell types grow and extend to their target regions in developing embryos. There are common territories that are navigated by these cell types: both cells grow through the rostral portion of the somitic sclerot...

journal_title：Cell adhesion & migration

authors： Krull CE

更新日期：2010-10-01 00:00:00

abstract：:The leukocyte adhesion cascade is of critical importance for both the maintenance of immune homeostasis and the ability of immune cells to perform effector functions. Here, we present data showing CD4+ T cells migrate upstream (against the direction of flow) after completing the leukocyte adhesion cascade on surfaces ...

journal_title：Cell adhesion & migration

authors： Anderson NR,Buffone A Jr,Hammer DA

更新日期：2019-12-01 00:00:00

abstract：:The mechanical and structural properties of the extracellular matrix (ECM) play an important role in regulating cell fate. The natural ECM has a complex fibrillar structure and shows nonlinear mechanical properties, which are both difficult to mimic synthetically. Therefore, systematically testing the influence of ECM...

journal_title：Cell adhesion & migration

authors： Bruekers SM,Jaspers M,Hendriks JM,Kurniawan NA,Koenderink GH,Kouwer PH,Rowan AE,T S Huck W

更新日期：2016-09-02 00:00:00

abstract：:The p53 transcription factor, discovered in 1979 ( 1;2) , is well known as a potent suppressor of tumor development by inhibiting cell cycle progression, and promoting senescence or apoptosis, when the genome is compromised or under oncogenic stress ( 3) . Accumulating evidence has pointed to an alternative role of p5...

journal_title：Cell adhesion & migration

authors： Mak AS

更新日期：2011-03-01 00:00:00

abstract：:In the cortex of a motile cell, membrane-anchored actin filaments assemble into structures of varying shape and function. Filopodia are distinguished by a core of bundled actin filaments within finger-like extensions of the membrane. In a recent paper by Medalia et al(1) cryo-electron tomography has been used to recon...

journal_title：Cell adhesion & migration

authors： Gerisch G,Weber I

更新日期：2007-07-01 00:00:00

abstract：:For successful transplantation of Hematopoietic Stem cells (HSCs), it is quite necessary that efficient homing, engraftment and retention of HSC self-renewal capacity takes place, which is often restricted due to inadequate number of adult HSCs. Here, we report that short-term ex-vivo treatment of mouse bone marrow mo...

journal_title：Cell adhesion & migration

authors： Khanna A,Indracanti N,Chakrabarti R,Indraganti PK

更新日期：2020-12-01 00:00:00

abstract：:Since the time it was pioneered in 1992, intravital imaging of tumors at cellular resolution has offered us the extremely important opportunity of "seeing biology." However, until now, most studies were monitoring tumor cell behavior in the same animal over short times, requiring the combining of acquired data into a ...

journal_title：Cell adhesion & migration

authors： Gligorijevic B,Condeelis J

更新日期：2009-10-01 00:00:00

abstract：:The aim of this study was to compare uniaxial traction forces exerted by different cell types using a novel sensor design and to test the dependence of measured forces on cytoskeletal integrity. The sensor design detects forces generated between 2 contact points by cells spanning a gap. The magnitude of these forces v...

journal_title：Cell adhesion & migration

authors： Swierczewski R,Hedley J,Redfern CP

更新日期：2016-05-03 00:00:00

abstract：:In addition to its well-defined role as an antagonist in apoptosis, we propose that BCL2 may act as an intracellular suppressor of cell motility and adhesion under certain conditions. Our evidence shows that, when over-expressed in both cancer and non-cancer cells, BCL2 can form a complex with actin and gelsolin that ...

journal_title：Cell adhesion & migration

authors： Ke H,Zhang JY,Akiyama SK,French JE

更新日期：2011-01-01 00:00:00

abstract：:Podosomes are small, circular adhesions formed by cells such as osteoclasts, macrophages, dendritic cells, and endothelial cells. They comprise a protrusive actin core module and an adhesive ring module composed of integrins and cytoskeletal adaptor proteins such as vinculin and talin. Furthermore, podosomes are assoc...

journal_title：Cell adhesion & migration

authors： van den Dries K,Bolomini-Vittori M,Cambi A

更新日期：2014-01-01 00:00:00

abstract：:The critical role of migration and invasion in cancer metastasis warrants new therapeutic approaches targeting the machinery regulating cell migration and invasion. While 2-dimensional (2D) models have helped identify a range of adhesion molecules, cytoskeletal components and regulators that are potentially important ...

journal_title：Cell adhesion & migration

authors： Bradbury P,Fabry B,O'Neill GM

更新日期：2012-09-01 00:00:00

abstract：:The conserved polarity proteins Par6 and aPKC regulate cell polarization processes. However, increasing evidence also suggests that they play a role in oncogenic progression. During tumor progression, epithelial to mesenchymal transition (EMT) delineates an evolutionary conserved process that converts stationary epith...

journal_title：Cell adhesion & migration

authors： Gunaratne A,Di Guglielmo GM

更新日期：2013-07-01 00:00:00

abstract：:Spinal cord injury (SCI) has been regarded clinically as an irreversible damage caused by tissue contusion due to a blunt external force. Past research had focused on the analysis of the pathogenesis of secondary injury that extends from the injury epicenter to the periphery, as well as tissue damage and neural cell d...

journal_title：Cell adhesion & migration

authors： Shibuya S,Yamamoto T,Itano T

更新日期：2009-01-01 00:00:00

abstract：:Neurodegenerative diseases have become a global issue due to the aging population. These disorders affect a vast patient population and represent a huge area of unmet therapeutic need. Axon degeneration is a common pathological character of those neurodegenerative diseases. It results in the loss of communication betw...

journal_title：Cell adhesion & migration

authors： Wang J,He Z

更新日期：2009-01-01 00:00:00

abstract：:In this review, we summarized data on the formation and structure of the long and highly adhesive membrane tubulovesicular extensions (TVEs, membrane tethers or cytonemes) observed in human neutrophils and other mammalian cells, protozoan parasites and bacteria. We determined that TVEs are membrane protrusions charact...

journal_title：Cell adhesion & migration

authors： Galkina SI,Fedorova NV,Stadnichuk VI,Sud'ina GF

更新日期：2013-03-01 00:00:00

abstract：:Angiogenesis, the growth of new blood vessels from pre-existing vessels, is a process involving endothelial cell proliferation, migration and vascular tube formation. One of the key molecules that regulate this process is the integrin beta3 subunit, a cell adhesion receptor that forms a heterodimer with the integrin a...

journal_title：Cell adhesion & migration

authors： Hayashi H,Kume T

更新日期：2009-01-01 00:00:00

abstract：:The hypotheses emerging from basic research on colorectal liver metastases must be tested in clinical situations for the adaptation of current treatment strategies. Pre-metastatic niches have been shown to exist in human colorectal synchronous metastases, with the liver parenchyma adjacent to the synchronous liver met...

journal_title：Cell adhesion & migration

authors： Eveno C,Pocard M

更新日期：2012-11-01 00:00:00

abstract：:Integrins regulate cell attachment and migration through interactions with specific proteins in the extra-cellular matrix. Heterotrimeric G proteins are essential signal transduction proteins that intersect with integrin signaling to regulate fundamental cellular behaviors. Although integrin and G protein signaling of...

journal_title：Cell adhesion & migration

authors： Kong T,Xu D,Tran M,Denker BM

更新日期：2010-07-01 00:00:00

abstract：:During an infection, neutrophils are the first immune cells to arrive armed to clear the invading pathogen. In order to do so, neutrophils need to transmigrate from the peripheral blood through the endothelial layer toward the site of inflammation. This process is in most cases dependent on integrins, adhesion molecul...

journal_title：Cell adhesion & migration

authors： Langereis JD

更新日期：2013-11-01 00:00:00

abstract：:Visceral adipose tissue (VAT) may play a critical role in atherosclerotic cardiovascular disease. The goal of this study was to determine the effect of human VAT-released pro‑inflammatory cytokines on monocyte adhesion to the endothelium. The cytokine effects on monocyte adhesion to the endothelial cells (ECs) were te...

journal_title：Cell adhesion & migration

authors： Cejkova S,Kubatova H,Thieme F,Janousek L,Fronek J,Poledne R,Kralova Lesna I

更新日期：2019-12-01 00:00:00

abstract：:Eph signaling, which arises following stimulation by ephrins, is known to induce opposite cell behaviors such as promoting and inhibiting cell adhesion as well as promoting cell-cell adhesion and repulsion by altering the organization of the actin cytoskeleton and influencing the adhesion activities of integrins. Howe...

journal_title：Cell adhesion & migration

authors： Saeki N,Nishino S,Shimizu T,Ogawa K

更新日期：2015-01-01 00:00:00

abstract：:Coordinated changes of actin cytoskeleton and cell adhesion accompany maturation of lymphoid cells, their migration through lymphoid organs and to sites of inflammation, as well as metastasis of transformed cells. Here we discuss the central role of the actin-regulating adaptor protein, paxillin, during lymphocyte tra...

journal_title：Cell adhesion & migration

authors： Romanova LY,Mushinski JF

更新日期：2011-11-01 00:00:00

abstract：:Directional cell migration is essential for almost all organisms during embryonic development, in adult life and contributes to pathological conditions. This is particularly critical during embryogenesis where it is essential that cells end up in their correct, precise locations in order to build a normal embryo. Many...

journal_title：Cell adhesion & migration

authors： Carmona-Fontaine C,Matthews H,Mayor R

更新日期：2008-10-01 00:00:00

abstract：:It is well recognized that a number of proteins present within adhesion complexes perform discrete signaling functions outside these adhesion complexes, including transcriptional control. In this respect, β-catenin is a well-known example of an adhesion protein present both in cadherin complexes and in the nucleus wh...

journal_title：Cell adhesion & migration

authors： van den Berg MC,Burgering BM

更新日期：2014-01-01 00:00:00

abstract：:Growth factors regulate a diverse array of cellular functions including proliferation, survival, movement, and the ability to do this often involves interactions with the extracellular matrix (ECM) and particularly heparan sulfate proteoglycans (HSPGs). HSPGs have been shown to sequester growth factors, and to act as ...

journal_title：Cell adhesion & migration

authors： Symes K,Smith EM,Mitsi M,Nugent MA

更新日期：2010-10-01 00:00:00

abstract：:Cell migration requires a highly coordinated interplay between specialized plasma membrane adhesion complexes and the cytoskeleton. Protein phosphorylation/dephosphorylation modifications regulate many aspects of the integrin-cytoskeleton interdependence, including their coupling, dynamics, and organization to support...

journal_title：Cell adhesion & migration

authors： Arregui CO,González Á,Burdisso JE,González Wusener AE

更新日期：2013-09-01 00:00:00