Abstract：
:Gross total resection of large intracranial meningiomas (LIMs) can be challenging and cause significant morbidity and mortality. The aim of this systematic review is to determine the clinical effectiveness and safety of stereotactic radiosurgery (SRS) either as primary or adjuvant therapy for LIMs with tumors ≥2.5 cm in maximum dimension (tumor volume ≥8.1 cm3). A total of 452 tumors in 496 patients (350 female [69.3%] and 146 male [30.6%]) with median age 60 years (48-65 years) were included. The median tumor volume at the time of diagnosis was 16.7 cm3 (10-53.3 cm3). The tumors typically were located in the skull base (77.2%), whereas only 14.6% were in the supratentorial space. The median follow-up after SRS was 54 months (18-90 months). In total, 87.8% of patients were treated with single-session (SS) Gamma Knife radiosurgery (GKS), whereas the remaining 12.1% patients received non-SS GKS. Of 452 LIMs assessed for clinical response, 45.1% showed improvement and 15.7% deteriorated after SRS. Radiographic tumor control at last follow-up (2-7.5 years) ranged from 84% to 100%. Overall, radiation-induced toxicity occurred in 23% of patients, with the most common adverse effect being cranial nerve neuropathy (5.5%) and peritumoral edema (5.3%). Subgroup analysis revealed that there is 2-fold greater likelihood of improvement in clinical symptoms in patients with non-SS GKS than SS GKS (odds ratio 2.47; 95% confidence interval 1.38-4.44; P = 0.002). SRS is safe and effective in the treatment of LIMs as primary or adjuvant treatment. Further prospective studies are required to validate our results.
journal_name
World Neurosurgjournal_title
World neurosurgeryauthors
Fatima N,Meola A,Pollom E,Chaudhary N,Soltys S,Chang SDdoi
10.1016/j.wneu.2019.06.064subject
Has Abstractpub_date
2019-09-01 00:00:00pages
269-275eissn
1878-8750issn
1878-8769pii
S1878-8750(19)31606-7journal_volume
129pub_type
杂志文章abstract：OBJECTIVE:To determine the stability of fusion constructs with unilateral pedicle screw (UPS) or bilateral pedicle screw (BPS) fixation with and without an interbody implant using the lateral lumbar interbody (LLIF) approach. METHODS:Standard nondestructive flexibility tests were performed on 13 cadaveric lumbar speci...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.02.053
更新日期：2018-05-01 00:00:00
abstract：OBJECTIVE:To evaluate safety and effectiveness of the application of piezosurgery in en bloc laminectomy for the treatment of multilevel thoracic ossification of ligamentum flavum (MTOLF). METHODS:Forty-one cases who had MTOLF and underwent en bloc laminectomy from January 2012 to January 2017 were reviewed and divide...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.03.200
更新日期：2019-06-01 00:00:00
abstract：BACKGROUND:Reports of tuberculosis involving ≥4 contiguous spinal levels are rare. Surgery is often required in this population for neurological decompression and stabilization. These patients appear to be particularly predisposed to complications that include incomplete recovery of neurological function after decompre...
journal_title：World neurosurgery
pub_type： 杂志文章,评审
doi：10.1016/j.wneu.2016.02.026
更新日期：2016-05-01 00:00:00
abstract：OBJECTIVE:We developed a method for fabricating a three-dimensional hollow and elastic aneurysm model useful for surgical simulation and surgical training. In this article, we explain the hollow elastic model prototyping method and report on the effects of applying it to presurgical simulation and surgical training. M...
journal_title：World neurosurgery
pub_type： 杂志文章,评审
doi：10.1016/j.wneu.2013.10.032
更新日期：2015-03-01 00:00:00
abstract：OBJECTIVE:Idiopathic normal pressure hydrocephalus (iNPH) may present, besides the classic triad of symptoms, with extrapyramidal parkinsonianlike movement disorders. We present a randomized prospective study comparing adjustable ventriculoperitoneal (VP) shunt insertion plus dopamine oral therapy (group A) versus VP s...
journal_title：World neurosurgery
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.wneu.2016.03.004
更新日期：2016-06-01 00:00:00
abstract：OBJECTIVE:Several surgical treatment modalities, including lumboperitoneal or ventriculoperitoneal shunt surgery, subtemporal decompression, endovascular venous sinus stenting, optic nerve decompression (OND), were used in the management of idiopathic intracranial hypertension (IIH). Each surgical technique has differe...
journal_title：World neurosurgery
pub_type： 临床试验,杂志文章
doi：10.1016/j.wneu.2014.03.045
更新日期：2014-11-01 00:00:00
abstract：BACKGROUND:Patients with single brain metastasis (SBM) have better outcomes after stereotactic radiosurgery (SRS). We analyzed our SRS database to evaluate possible prognostic factors in patients with SBM. METHODS:A total of 584 patients with SBM were treated with SRS at our institution (2000-2012). Study end points w...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2017.04.156
更新日期：2017-08-01 00:00:00
abstract：OBJECTIVE:Geniculate neuralgia is an uncommon pain syndrome that can be severe and disabling and is difficult to diagnose. METHODS:The literature was reviewed for geniculate neuralgia, including anatomy, presentation, and treatment. A case illustration was presented that demonstrates the novel brainstem functional ima...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2012.11.053
更新日期：2013-12-01 00:00:00
abstract：BACKGROUND:Before the advent of radiosurgery, neurosurgical treatment of meningiomas typically involved gross total resection of the mass whenever surgery was deemed possible. Over the past 4 decades, though, Gamma Knife radiosurgery (GKRS) has proved to be an effective, minimally invasive means to control the growth o...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.06.152
更新日期：2019-10-01 00:00:00
abstract：BACKGROUND:Subarachnoid hemorrhage (SAH) induces widespread inflammation leading to cellular injury, vasospasm, and ischemia. Evidence suggests that progesterone (PROG) can improve functional recovery in acute brain injury owing to its anti-inflammatory and neuroprotective properties, which could also be beneficial in ...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2017.10.118
更新日期：2018-02-01 00:00:00
abstract：BACKGROUND:Spinal arteriovenous malformations (AVM) are an abnormal interconnection of vasculature in the spine than can lead to significant neurologic deficit if left untreated. OBJECTIVE:The objective of this study was to characterize how patients with spinal AVM initially presented, what treatment options were used...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.08.010
更新日期：2019-11-01 00:00:00
abstract：:Trepanation, the process of making a burr hole in the skull to access the brain, is an ancient form of a primitive craniotomy. There is widespread evidence of contributions made to this practice by ancient civilizations in Europe, Africa, and South America, where archaeologists have unearthed thousands of trepanned sk...
journal_title：World neurosurgery
pub_type： 历史文章,杂志文章,评审
doi：10.1016/j.wneu.2016.10.051
更新日期：2017-05-01 00:00:00
abstract：BACKGROUND:Primary Ewing sarcoma arising from the calvarial bone and/or underlying dura matter are relatively rarely reported in the literature. Even rarer are considered to be those that originate from the dura and proliferate in both directions, toward the brain parenchyma and through the dura invading the overlying ...
journal_title：World neurosurgery
pub_type： 杂志文章,评审
doi：10.1016/j.wneu.2019.06.036
更新日期：2019-09-01 00:00:00
abstract：OBJECTIVE:Spine trauma management in children varies from one team to another, and to date, no clear consensus has been reached. The goal of this study was to describe the epidemiology of spine trauma in children and evaluate the timing and techniques of surgery when it was required. METHODS:A retrospective review of ...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.03.134
更新日期：2019-06-01 00:00:00
abstract：BACKGROUND:Supratentorial extraventricular ependymoma (STEE) is an extremely rare central nervous system (CNS) neoplasm, the clinical characteristics and optimal treatment of which remain unclear. We retrospectively analyzed the clinical characteristics and treatment outcomes of 15 patients with STEE. METHODS:Fifteen ...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.05.192
更新日期：2018-10-01 00:00:00
abstract：OBJECTIVE:Although short-term clinical outcomes after basilar artery stent placement have been reported previously, effectiveness of intracranial stenting for vertebrobasilar artery occlusion in the acute phase of ischemic stroke is unclear. METHODS:We clinically investigated 8 patients with intracranial percutaneous ...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2016.09.106
更新日期：2017-01-01 00:00:00
abstract：OBJECTIVE:In selected cases, embolization can be indicated for very small unruptured intracranial aneurysms. Previous studies reported high intraprocedural rupture rates. Recent improvements of endovascular devices and availability of small, soft platinum coils may lead to improved safety and efficacy profiles. METHOD...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.05.070
更新日期：2019-08-01 00:00:00
abstract：OBJECTIVE:Resection of epidural thoracic spine tumors is uniquely challenging owing to the dangers posed by the surrounding anatomy and the unforgiving nature of the thoracic spinal cord. We assessed the preoperative and postoperative risk factors for 30-day morbidity and mortality in patients undergoing resection of t...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.08.195
更新日期：2018-12-01 00:00:00
abstract：:Calcified chronic subdural hematomas are an occurrence rarely seen in neurosurgical clinical practice. And when they occur bilaterally, the radiologic image they present is fascinating, as is the clinical presentation, but their management may be challenging. They have been reported to present with a multitude of neur...
journal_title：World neurosurgery
pub_type： 杂志文章,评审
doi：10.1016/j.wneu.2016.11.031
更新日期：2017-02-01 00:00:00
abstract：BACKGROUND:The long-term outcomes of patients with intraprocedural aneurysm rupture (IPR) during endovascular coiling of unruptured intracranial aneurysms (UIAs) remain unclear. We investigated the long-term outcomes and predictors of neurological outcomes in patients who sustained IPR during coil embolization of UIAs....
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.10.038
更新日期：2020-02-01 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章,评审
doi：10.1016/j.wneu.2015.06.024
更新日期：2015-11-01 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.08.134
更新日期：2018-12-01 00:00:00
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journal_title：World neurosurgery
pub_type： 历史文章,杂志文章
doi：10.1016/j.wneu.2017.02.021
更新日期：2017-07-01 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.05.156
更新日期：2019-09-01 00:00:00
abstract：:The insula plays a crucial role in speech planning due to its connections with cortical and subcortical areas. Surgical management of cavernous malformation (CM) of the insula consists of total resection of the lesion and the surrounding gliosis to avoid or reduce seizures. When located in the dominant hemisphere, an ...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.10.220
更新日期：2019-02-01 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2016.09.085
更新日期：2017-01-01 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.01.265
更新日期：2019-05-01 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.03.222
更新日期：2018-07-01 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章,meta分析
doi：10.1016/j.wneu.2018.08.173
更新日期：2018-12-01 00:00:00
abstract：BACKGROUND:Fusiform aneurysms are challenging lesions to manage given their poorly understood natural history and lack of a distinct neck. Historically, they have been treated surgically but endovascular management has recently evolved as a viable alternative. In this case, we describe a novel flow diversion technique ...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.05.245
更新日期：2019-09-01 00:00:00
