Abstract:
BACKGROUND:Patients with single brain metastasis (SBM) have better outcomes after stereotactic radiosurgery (SRS). We analyzed our SRS database to evaluate possible prognostic factors in patients with SBM. METHODS:A total of 584 patients with SBM were treated with SRS at our institution (2000-2012). Study end points were overall survival (OS), and distant and local intracranial progression-free survival (DPFS and LPFS, respectively). Multivariable analysis was performed to develop prognostic models. RESULTS:Median OS was 10.8 months. A total of 196 patients (36.7%) had distant progression and 102 patients (19.2%) had local progression. New SBM prognostic indices (SPIs) were devised for OS, DPFS, and LPFS. Graded prognostic assessment, neurologic symptoms (P = 0.01), and tumor volume (P = 0.02) were independently associated with OS. The SPI for OS was defined: unfavorable (OS, 7.3 months), intermediate (OS, 10.6 months), and favorable (OS, 19.8 months). For DPFS, age (P = 0.0029), tumor volume (P = 0.0002), and previous whole-brain radiotherapy (P = 0.027) were prognostic and were used to define SPI for DPFS: favorable (6-month cumulative incidence failure [CIF], 10.9%), intermediate (6-month CIF, 16.7%), and unfavorable (6-month CIF, 26.0%) (P < 0.001). For LPFS, graded prognostic assessment (P = 0.0012) and tumor volume (P = 0.0004) were significant, and defined 2 groups in the LPFS SPI: unfavorable (6-month CIF, 12.3%) and favorable (6-month CIF, 6%) (P < 0.001). CONCLUSIONS:This is the largest series of patients with SBM treated with SRS analyzed for OS, LPFS, and DPFS. SPI was devised for end points. Tumor volume had a significant association with all 3 end points. Neurologic symptoms, age, and previous whole-brain radiotherapy were also found to be prognostic.
journal_name
World Neurosurgjournal_title
World neurosurgeryauthors
Bennett EE,Angelov L,Vogelbaum MA,Barnett GH,Chao ST,Murphy ES,Yu JS,Suh JH,Jia X,Stevens GHJ,Ahluwalia MS,Mohammadi AMdoi
10.1016/j.wneu.2017.04.156subject
Has Abstractpub_date
2017-08-01 00:00:00pages
229-238eissn
1878-8750issn
1878-8769pii
S1878-8750(17)30664-2journal_volume
104pub_type
杂志文章abstract:OBJECTIVE:Robotic surgical systems are used worldwide in various fields. In this study, we present the advantages and disadvantages of the most common robotic surgical system, the da Vinci Xi system, in the supracerebellar transtentorial approach to the mesial temporal region and discuss options for its integration int...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2020.07.153
更新日期:2020-12-01 00:00:00
abstract:BACKGROUND:The reported incidence of postoperative ileus (POI) after spine surgery depends on the surgical approach and definition used. It is therefore possible that the overall incidence is substantially higher than previously thought. POI has consequences for both the patient and hospital resources, and can signific...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2019.08.062
更新日期:2019-12-01 00:00:00
abstract::A 49-year-old woman presented with sudden-onset headache and meningismus. Computed tomography scan revealed a posterior fossa subarachnoid hemorrhage extending from the foramen magnum to the ambient cistern. Angiography showed a pial extramedullary arteriovenous malformation (AVM) at the lateral ventral surface of the...
journal_title:World neurosurgery
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doi:10.1016/j.wneu.2020.04.197
更新日期:2020-07-01 00:00:00
abstract:OBJECTIVE:The primary training in any surgical practice starts with tissue handling and effective hemostasis. Neurosurgical procedures start with an incision in the scalp and require summative use of mechanical hemostats and bipolar coagulation to achieve hemostasis. Though Raney clips are the most popular and effectiv...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2018.09.182
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Ninety-five percent of the Hong Kong population is Chinese, and no previous epidemiological study has focused on spontaneous subarachnoid hemorrhage (SAH) in Hong Kong. These data would have significant public health implications and can guide future resource allocations and service development in Hong Kong....
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2013.07.128
更新日期:2014-03-01 00:00:00
abstract::A patient presented with progressive ischemic stroke and received mechanical thrombectomy with a Solitaire FR device 29 days after stroke onset. The occluded V4 segment of the left vertebral artery showed a double rail sign on angiography, which indicated that the occlusion might have been caused by embolism instead o...
journal_title:World neurosurgery
pub_type:
doi:10.1016/j.wneu.2020.03.223
更新日期:2020-09-01 00:00:00
abstract:OBJECTIVE:We reviewed data on the epidemiology of epilepsy in the United States and estimated the prevalence and incidence of drug-resistant temporal lobe epilepsy (TLE) due to hippocampal sclerosis (HS) based on extrapolation from the available data drawn from the literature. METHODS:We searched the electronic databa...
journal_title:World neurosurgery
pub_type: 杂志文章,评审
doi:10.1016/j.wneu.2016.12.074
更新日期:2017-03-01 00:00:00
abstract:OBJECTIVE:Postoperative infection is a potentially dramatic consequence in endoscopic endonasal surgery. The aim of this study was to assess the efficacy of our intraoperative antibiotic prophylaxis by analyzing the risk factors of postoperative meningitis in our series. METHODS:Each endoscopic endonasal procedure per...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2017.07.075
更新日期:2017-10-01 00:00:00
abstract:BACKGROUND:Local hemostatic agents have been used in the neurosurgical field for many years; it is safe and efficient with no fatal complication reported in the literature. We routinely used a gelatin-thrombin hemostatic agent (FloSeal Hemostatic Matrix) for hemostasis in minimally invasive endoscopic-assisted surgery ...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2019.03.030
更新日期:2019-06-01 00:00:00
abstract:BACKGROUND:Ossification of the posterior longitudinal ligament (OPLL) is a 3-dimensional (3D) disease that causes cervical myelopathy. The conventional 2-dimensional (2D) measurement of OPLL has limitations in estimating cord compression and myelopathy. In this study, we attempted to use 3D computed tomography (CT) and...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2018.03.222
更新日期:2018-07-01 00:00:00
abstract:OBJECTIVE:Recognition of congenital tethered cervical cord in adults and literature review. METHODS:Retrospective review of adult onset tethered cervical cord patients (age >20 years). RESULTS:Three adults were identified; 2 women and 1 man, average age 47 years. The presenting symptoms were neck pain with restricted...
journal_title:World neurosurgery
pub_type: 杂志文章,评审
doi:10.1016/j.wneu.2020.10.107
更新日期:2020-10-24 00:00:00
abstract:OBJECTIVE:Percutaneous endoscopic lumbar discectomy is an effective way to treat lumbar disc herniation. Traditional preoperative planning based on a 2-dimensional method by magnetic resonance/computed tomography may cause inaccuracy of puncture during surgery. We used virtual reality to stimulate a surgery environment...
journal_title:World neurosurgery
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.wneu.2018.08.082
更新日期:2019-03-01 00:00:00
abstract:BACKGROUND:A cavernous malformation (CM) with trigeminal neuralgia (TN) is relatively rare. We report a patient who presented with TN caused by a CM in the cerebellopontine angle. CASE DESCRIPTION:A 37-year-old man presented with a history of episodic, shock-like, right facial pain of 2 months' duration. Neurologic ex...
journal_title:World neurosurgery
pub_type:
doi:10.1016/j.wneu.2019.12.167
更新日期:2020-05-01 00:00:00
abstract:OBJECTIVE:Positional vertebral artery occlusion (PVAO) has a fundamental problem in the definition. We analyzed the long-term outcomes with a redefinition of the rare clinical entities as PVAO for a broader conceptualization, and discuss the efficacy of fusion surgery as a treatment option. METHODS:We analyzed the cli...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2018.03.089
更新日期:2018-06-01 00:00:00
abstract:BACKGROUND:Because peripheral nerve surgery has become more common in recent years, the pressure to increase this procedure's health care safety and cost-effectiveness has increased. Given our limited understanding, we evaluated prospectively identified and randomly sampled patients who underwent peripheral nerve surge...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2016.07.023
更新日期:2016-10-01 00:00:00
abstract:OBJECTIVES:The pathophysiology of traumatic brain injury (TBI) largely involves the brains vascular structural integrity. We analyzed the value of an intraoperative cortical indocyanine green (ICG) angiography in patients with severe TBI and acute subdural hematoma who underwent decompressive craniectomy. METHODS:ICG-...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2017.01.054
更新日期:2017-05-01 00:00:00
abstract:BACKGROUND:Spinal cord injury (SCI) without computed tomography evidence of trauma is underreported in adults and is considered a subtype of SCI with relatively good outcome. Despite this, few studies have been performed to determine specific imaging-related prognostic factors. Our objective is to describe the imaging ...
journal_title:World neurosurgery
pub_type: 杂志文章,多中心研究
doi:10.1016/j.wneu.2016.12.005
更新日期:2017-03-01 00:00:00
abstract:OBJECTIVE:We sought to determine the location of kinesthetic cell clusters within the subthalamic nucleus (STN) on magnetic resonance imaging, adjusted for interindividual anatomic variability by employing the medial STN border as a reference point. METHODS:We retrospectively localized microelectrode recording-defined...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2020.04.160
更新日期:2020-07-01 00:00:00
abstract:BACKGROUND:Approximately 2%-10% of all central nervous system tumors are primary spinal cord tumors (SCTs). Spinal cord glioblastoma is a rare tumor type accounting for 1%-3% of all SCTs and 7.5% of all spinal cord gliomas. Notably, the small-cell variant of spinal cord glioblastoma is even rarer with only 2 previously...
journal_title:World neurosurgery
pub_type: 杂志文章,评审
doi:10.1016/j.wneu.2018.07.007
更新日期:2018-10-01 00:00:00
abstract:BACKGROUND:One of the most valuable innovations in high-grade glioma surgery is 5-aminolevulinic acid (5-ALA). Fluorescence is a specific and sensitive indicator of metabolically active tumor tissue. In the published literature, the main focus has been placed on false-negative cases, with only a few articles addressing...
journal_title:World neurosurgery
pub_type: 杂志文章,评审
doi:10.1016/j.wneu.2020.01.238
更新日期:2020-05-01 00:00:00
abstract:OBJECTIVE:Recurrent chronic subdural hematoma (CSDH) is not rare. Some studies have demonstrated the role of dexamethasone in the medical management of chronic subdural hematoma. However, no systematic study in the treatment of recurrent CSDH has been published. The aim of our study is to evaluate the efficacy and safe...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2017.05.135
更新日期:2017-09-01 00:00:00
abstract:BACKGROUND:Single-level open lumbar microdiscectomy surgery is one of the most straightforward and effective spinal surgeries performed by spinal surgeons today to treat disk herniation. Although a common operation, little in the literature is reported on the exact overall time, cost, and effort associated with the per...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2018.07.239
更新日期:2018-11-01 00:00:00
abstract:BACKGROUND:The use of titanium alloy (Ti) rods is frequently associated with rod fracture after spinal fixation. To address this issue, cobalt chrome (CoCr) rods, which are advantageous because of their greater strength and resistance to fatigue relative to Ti rods, have been introduced. The purpose of the present stud...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2017.04.031
更新日期:2017-07-01 00:00:00
abstract:BACKGROUND:Brainstem cavernous malformations (CMs) are benign lesions, often show an acute onset, and result in a high rate of morbidity. Surgical resection could inhibit the progressive deterioration of neurologic function caused by repetitive hemorrhage. This study aimed to summarize timing, approaches, and technique...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2018.11.008
更新日期:2019-02-01 00:00:00
abstract:BACKGROUND:Neurosurgical spine specialists receive considerable amounts of industry support that may impact the cost of care. The aim of this study was to evaluate the association between industry payments received by spine surgeons and the total hospital and operating room (OR) costs of an anterior cervical discectomy...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2020.08.023
更新日期:2020-11-01 00:00:00
abstract::Biochemical remission of adrenocorticotropic hormone (ACTH)-secreting macroadenomas can be challenging to achieve.1,2 Staying outside the adenoma pseudocapsule is an important technique to achieve gross total resection.1-3 Dural invasion is an important recognized factor that can prevent biochemical remission. In part...
journal_title:World neurosurgery
pub_type:
doi:10.1016/j.wneu.2020.09.087
更新日期:2020-12-01 00:00:00
abstract:BACKGROUND:Spinal subdural hematomas (SSDHs) are rare and usually associated with bleeding diatheses, trauma, iatrogenic injury, spinal vascular malformations, or intraspinal tumors. CASE DESCRIPTION:We report a case of a 75-year-old man who developed a symptomatic lumbosacral SSDH after undergoing resection of a righ...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2017.08.189
更新日期:2017-12-01 00:00:00
abstract:OBJECTIVE:We aimed to describe our single-center experience in treating cerebellar arteriovenous malformations (AVMs) with microsurgical resection. METHODS:During a 16-year period, 181 patients with cerebellar AVMs were surgically treated at the Department of Neurosurgery in Beijing Tiantan Hospital. Patient functiona...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2016.08.059
更新日期:2016-11-01 00:00:00
abstract:BACKGROUND:Oncotic aneurysm is a rare condition with a high mortality rate. Because no consensus has been reached regarding therapeutic strategy for ruptured oncotic aneurysm, treatment remains challenging. CASE DESCRIPTION:A 35-year-old woman developed sudden onset of severe headache. Computed tomography showed subar...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2018.02.049
更新日期:2018-05-01 00:00:00
abstract:OBJECTIVE:To elucidate the role of endoscopic third ventriculostomy (ETV) in patients with secondary and idiopathic communicating hydrocephalus (HCP). METHODS:A series of 36 patients with communicating HCP (21 men and 15 women) were treated by ETV between November 2007 and February 2010. The patients age ranged from 1...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2011.06.038
更新日期:2012-03-01 00:00:00