Abstract：
BACKGROUND:One of the most valuable innovations in high-grade glioma surgery is 5-aminolevulinic acid (5-ALA). Fluorescence is a specific and sensitive indicator of metabolically active tumor tissue. In the published literature, the main focus has been placed on false-negative cases, with only a few articles addressing false positivity. The aim of the article was to highlight settings in which 5-ALA fluorescence does not necessarily mean tumor and to point out conditions in which intraoperative 5-ALA fluorescence has to be critically interpreted. METHODS:Using PubMed, a review of pertinent literature was done to specifically investigate all conditions, including non-neoplastic and other metabolically active lesions, that can mimic high-grade gliomas and cause a misleading intraoperative diagnosis. In addition, an institutional case characterized by strong 5-ALA fluorescence in radionecrosis is presented. RESULTS:Literature results were grouped in 2 main categories according to the field of application: oncologic setting (9 articles and 1 institutional case) and nononcologic settings (5 articles). CONCLUSIONS:As reported, 5-ALA-induced fluorescence is not limited to glioma but is also evident in nonglioma and non-neoplastic conditions. Critical interpretation of intraoperative fluorescence is therefore mandatory in recurrences and in atypical cases that might hinder alternative diagnoses.
journal_name
World Neurosurgjournal_title
World neurosurgeryauthors
La Rocca G,Sabatino G,Menna G,Altieri R,Ius T,Marchese E,Olivi A,Barresi V,Della Pepa GMdoi
10.1016/j.wneu.2020.01.238subject
Has Abstractpub_date
2020-05-01 00:00:00pages
187-193eissn
1878-8750issn
1878-8769pii
S1878-8750(20)30256-4journal_volume
137pub_type
杂志文章,评审abstract：OBJECTIVE:Incidence of intraprocedural rupture (IPR) during endovascular coiling is reported to be 2%-5%. We reviewed a single-center experience of IPR during coil embolization of unruptured intracranial aneurysms. METHODS:Between January 2011 and April 2016, 849 patients were treated with endovascular therapy for unr...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2017.05.147
更新日期：2017-09-01 00:00:00
abstract：OBJECTIVE:We sought to document our experience in managing a rare complex of traumatic posterolateral atlantoaxial dislocation combined with locked lateral mass and type II odontoid fracture. METHOD:A 30-year-old male patient was referred to the author's department. He complained of a decrease in neck range of motion ...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.03.191
更新日期：2018-06-01 00:00:00
abstract：OBJECTIVE:Meningeal hemangiopericytoma (HPC) is a rare, aggressive central nervous system tumor that tends to invade locally and to metastasize, and has a high rate of recurrence. METHODS:This study presents a retrospective review of patients managed for intracranial HPC at Rome University Hospital. RESULTS:A total o...
journal_title：World neurosurgery
pub_type： 杂志文章,评审
doi：10.1016/j.wneu.2013.11.009
更新日期：2014-03-01 00:00:00
abstract：BACKGROUND:Dermoid cysts are rare intracranial tumors that are most commonly found infratentorially and along the midline. Characterized by slow growth and often found incidentally, these lesions can nonetheless have severe complications, notably rupture leading to chemical meningitis. They infrequently present as a su...
journal_title：World neurosurgery
pub_type： 杂志文章,评审
doi：10.1016/j.wneu.2016.05.037
更新日期：2016-09-01 00:00:00
abstract：BACKGROUND:Clinical features and prognosis of sensory disturbance in spinal dural arteriovenous fistula (SDAVF) have not been well documented. Here we report long-term outcomes and detailed sensory evaluations of surgically treated SDAVF, including 14 patients with the craniocervical fistulas. METHODS:Thirty-four cons...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2010.01.003
更新日期：2010-04-01 00:00:00
abstract：BACKGROUND:Experiencing cranial surgery under awake conditions may expose patients to considerable psychological strain. METHODS:This study aimed to investigate the occurrence and course of psychological sequelae following awake craniotomy (AC) for brain tumors in a series of 20 patients using a broad, validated psych...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.05.156
更新日期：2019-09-01 00:00:00
abstract：OBJECTIVE:Two main types of embolic protection devices have been used during carotid artery stenting (CAS): distal protection devices (DPDs) and proximal protection devices (PPDs). We compared the complications, clinical outcomes, and new ischemic lesions on diffusion-weighted magnetic resonance imaging (DWI) studies b...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.12.121
更新日期：2020-03-01 00:00:00
abstract：BACKGROUND:Occipital artery pseudoaneurysms are extremely rare pathologies that manifest after traumatic injury; only 11 cases have been reported in the literature. Because of their low incidence and vague symptoms, the initial diagnosis can be difficult. However, for correctly diagnosed occipital artery pseudoaneurysm...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2016.01.095
更新日期：2016-05-01 00:00:00
abstract：OBJECTIVE:Extracranial to intracranial (EC-IC) high-flow bypass using radial artery or saphenous vein (SV) graft has remained vital for complex aneurysms. If an Allen test is positive, the radial artery cannot be harvested because of poor palmer collateral circulation. The valves are thought to be one of causes of SV g...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2015.12.009
更新日期：2016-03-01 00:00:00
abstract：OBJECTIVE:Metastases to the spine are a common manifestation of breast cancer leading to considerable reduction in the patient's quality of life. Physicians must consider the different treatments available to decrease pain, reduce tumor burden, and ensure spinal stability to prevent neurological compromises. The first ...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2014.08.010
更新日期：2014-12-01 00:00:00
abstract：BACKGROUND:This is an original report describing the long-term follow-up outcome of a cranioplasty. A large calvarial bone defect of a child was reconstructed with a bioactive and biostable non-metallic implant. CASE DESCRIPTION:This is a case study of a young child with an infantile fibrosarcoma of occipital bone. Th...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.01.028
更新日期：2019-01-23 00:00:00
abstract：OBJECTIVE:The goal of this study was to assess the indications of revision for vagal nerve stimulation at a single institution in an adult population with drug-resistant epilepsy. METHODS:This was a retrospective review of a prospectively collected database who underwent vagal nerve stimulator implantation for drug-re...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.09.008
更新日期：2018-12-01 00:00:00
abstract：:The Foundation for International Education in Neurological Surgery (FIENS) was established in 1969 for the purpose of promoting neurosurgical education and patient care in the developing world. Ghana, the first African site, was adopted in 1989. In 2005 a neurosurgical training program was developed for Ethiopia, Keny...
journal_title：World neurosurgery
pub_type： 历史文章,杂志文章
doi：10.1016/j.wneu.2010.03.007
更新日期：2010-04-01 00:00:00
abstract：BACKGROUND:More than 120,000 anterior cervical discectomy and fusions (ACDFs) are performed annually. Pseudarthrosis is a potential delayed adverse event that affects up to 33% of patients. The degree to which this adverse event affects both patient quality-of-life (QOL) outcomes and health care costs is poorly underst...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.09.104
更新日期：2020-01-01 00:00:00
abstract：OBJECTIVE:This study aimed to compare the ultrasound (US)-guided erector spinae plane block (ESPB) and modified-thoracolumbar interfascial plane (mTLIP) block for postoperative pain management in lumbar discectomy surgery patients. METHODS:A total of 90 patients scheduled for lumbar discectomy were randomly assigned i...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2020.09.077
更新日期：2020-12-01 00:00:00
abstract：OBJECTIVES:To prospectively evaluate the diagnostic value of 3.0 Tesla magnetic resonance 3-dimensional sampling perfection with application-optimized contrast using different flip angle evolution (3D-SPACE) in the detection of sinus wall invasion and sinus patency in parasinus meningiomas. METHODS:In this study, 28 p...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.07.223
更新日期：2018-11-01 00:00:00
abstract：BACKGROUND:Major depressive disorder is a common and disabling illness and is the leading cause of disability worldwide. Despite aggressive medical, behavioral, and electroconvulsive therapies, a significant number of patients remain refractory to treatment. Deep brain stimulation (DBS) has proven efficacy in neurobeha...
journal_title：World neurosurgery
pub_type： 历史文章,杂志文章,评审
doi：10.1016/j.wneu.2012.10.068
更新日期：2013-09-01 00:00:00
abstract：BACKGROUND:Abscess coexisting within a brain tumor is rare. Case reports in the literature primarily consist of sellar pathology and parenchymal lesions, including meningioma, glioma, and metastases. We report a case of glioblastoma with an intratumoral abscess in a middle-aged patient with no prior invasive procedure ...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.02.036
更新日期：2018-05-01 00:00:00
abstract：BACKGROUND:Olfactory neuroblastoma (ON) is a highly aggressive and locally recurrent neoplasm. Distant systemic metastases are not uncommon, but remote leptomeningeal dissemination is extremely rare. CASE DESCRIPTION:We report 2 cases of ON previously treated with endoscopic endonasal radical surgical resection and ra...
journal_title：World neurosurgery
pub_type：
doi：10.1016/j.wneu.2019.11.042
更新日期：2020-02-01 00:00:00
abstract：:Intracranial arteriovenous malformations (AVMs) are congenital lesions frequently diagnosed as a result of hemorrhage or other neurological symptoms. Prevention of such devastating neurological injury has promoted a variety of treatment strategies. The rich history of multimodal therapy in the treatment of AVMs includ...
journal_title：World neurosurgery
pub_type： 杂志文章,评审
doi：10.1016/j.wneu.2011.01.042
更新日期：2011-05-01 00:00:00
abstract：BACKGROUND:The role of inflammatory response in the pathophysiology of subarachnoid hemorrhage (SAH) is being increasingly recognized. This study analyzed the impact of cellular and biochemical markers of early inflammatory response to ictus on outcome after SAH. METHODS:Patients with SAH were prospectively studied fo...
journal_title：World neurosurgery
pub_type： 临床试验,杂志文章
doi：10.1016/j.wneu.2016.02.049
更新日期：2016-06-01 00:00:00
abstract：OBJECTIVE:Although many studies have evaluated risk factors associated with hydrocephalus after aneurysmal subarachnoid hemorrhage, specific ventricle volume changes after subarachnoid hemorrhage have not been evaluated. We sought to evaluate factors predicting ventricle volume enlargement in patients with aneurysmal s...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2017.08.076
更新日期：2017-12-01 00:00:00
abstract：INTRODUCTION:Intradural spinal arachnoid cysts (SACs) are among many etiologies for syringomyelia. Consequentially, neurologic symptoms arise such as pain, gait disturbance, and bladder dysfunction. Identification of SAC on magnetic resonance imaging (MRI) can be challenging, as SACs can be fenestrated or in the form o...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2015.11.004
更新日期：2016-03-01 00:00:00
abstract：BACKGROUND:Atlantoaxial instability owing to bone erosions in a patient with ankylosing spondylitis (AS) is rare. We describe the radiographic characteristics, pathology, and treatment of a patient with this rare clinical manifestation and review the literature. CASE DESCRIPTION:A 36-year-old man with an 8-year histor...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.10.155
更新日期：2019-02-01 00:00:00
abstract：OBJECTIVE:Giant sacral schwannomas are rare and difficult to treat. Unexpected neurologic deficits after surgery and tumor recurrence should be considered when surgery is performed. We attempt to remove the tumors via piecemeal total or subtotal excision, leaving parts of the capsule adjacent to nerves to preserve the ...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.05.113
更新日期：2019-09-01 00:00:00
abstract：BACKGROUND:Giant cell tumors (GCTs) are benign tumors with a predilection for the epimetaphyseal region of the long bones. GCTs involving the skull base are rare, and only a few available cases have been reported. Surgical gross total resection is the recommended method of treatment for GCTs. In the case of skull base ...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.07.207
更新日期：2018-11-01 00:00:00
abstract：BACKGROUND:When it comes to evacuating intracranial hemorrhagic lesions in patients with traumatic brain injury (TBI), neurosurgeons perform either a craniotomy or a decompressive craniectomy (DC). The aim of the present study was to estimate the impact of DC on outcomes in elderly patients. METHODS:This retrospective...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2016.01.071
更新日期：2016-05-01 00:00:00
abstract：BACKGROUND:Microscopic training is essential for development of neurosurgical skills. A range of models is reported in the literature for this purpose, including live animals, exvivo, and synthetic material. Among the factors involved in selection and development of a training station, cost is a decisive one. METHODS:...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.06.089
更新日期：2019-10-01 00:00:00
abstract：BACKGROUND:Scalp arteriovenous malformation is a rare disease. In terms of treatment, surgical removal is often effective and performed. With the development of endovascular treatments, a combination of surgical removal and embolization is now often performed. CASE DESCRIPTION:A 44-year-old man presented with a mass i...
journal_title：World neurosurgery
pub_type：
doi：10.1016/j.wneu.2020.02.138
更新日期：2020-06-01 00:00:00
abstract：BACKGROUND:Preoperative embolization is established as an advantageous adjunct in multimodality treatment of cerebral arteriovenous malformations (AVMs). However, the benefit of preoperative embolization in AVMs with favorable surgical risk profile is debatable, because it has yet to be supported by evidence in compara...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2017.05.026
更新日期：2017-08-01 00:00:00
