Intraoperative Indocyanine Green-Based Cortical Perfusion Assessment in Patients Suffering from Severe Traumatic Brain Injury.


OBJECTIVES:The pathophysiology of traumatic brain injury (TBI) largely involves the brains vascular structural integrity. We analyzed the value of an intraoperative cortical indocyanine green (ICG) angiography in patients with severe TBI and acute subdural hematoma who underwent decompressive craniectomy. METHODS:ICG-derived fluorescence curves of cortex and cerebral vessels were recorded by the use of software integrated into a surgical microscope in 10 patients. The maximum intensity, rise time (RT), time to peak, and residual fluorescence intensity (FI) were estimated from cortical arteries, the parenchyma, and veins. RESULTS:ICG-derived fluorescence parameters were correlated with the short-term outcome 3 months after discharge. Five patients had a favorable and 5 an unfavorable outcome. Patients with a favorable outcome showed a significant longer RT in the arteries and a trend towards a significant longer RT in the veins. Overall mean residual FI was 47.5 ± 6.8% for the arteries, 45.0 ± 7% for the parenchyma and 57.6 ± 6% for the veins. The residual FI of the parenchyma and the veins was significantly greater in patients with an unfavorable clinical outcome. CONCLUSIONS:Patients with an unfavorable clinical outcome showed an altered shape of the ICG-derived fluorescence curve, a shorter increase of the ICG-derived fluorescence intensity in the cortical arteries, and significantly greater residual fluorescence intensity. These observations are likely a correlate of an increased intracranial pressure, a capillary leak, and venous congestion. Intraoperative quantification of the ICG-derived fluorescence might help to appreciate the clinical outcome in patients with severe TBI.


World Neurosurg


World neurosurgery


Kamp MA,Sarikaya-Seiwert S,Petridis AK,Beez T,Cornelius JF,Steiger HJ,Turowski B,Slotty PJ




Has Abstract


2017-05-01 00:00:00












  • Spinal Cord Herniation After Cervical Corpectomy with Cerebrospinal Fluid Leak: Case Report and Review of the Literature.

    abstract:BACKGROUND:Spinal cord herniation (SCH) is rare, is mostly idiopathic, and occurs predominantly in the thoracic spine. SCH is less common in the cervical spine and has been reported after posterior cervical spine surgery associated with the development of pseudomeningoceles. Two cases of SCH have been reported after an...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Guppy KH,Silverthorn JW

    更新日期:2017-04-01 00:00:00

  • Effectiveness of Intracranial Percutaneous Transluminal Angioplasty or Stenting for Atherosclerotic Vertebrobasilar Artery Occlusion in the Acute Phase of Ischemic Stroke.

    abstract:OBJECTIVE:Although short-term clinical outcomes after basilar artery stent placement have been reported previously, effectiveness of intracranial stenting for vertebrobasilar artery occlusion in the acute phase of ischemic stroke is unclear. METHODS:We clinically investigated 8 patients with intracranial percutaneous ...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Wajima D,Aketa S,Nakagawa I,Masui K,Yonezawa T,Enami T,Nishida F,Nakase H

    更新日期:2017-01-01 00:00:00

  • Training in endovascular surgical neuroradiology.

    abstract:BACKGROUND:During the past few years, the field of endovascular surgical neuroradiology has been expanding. Neurosurgeons, radiologists, and neurologists are currently being trained. We analyzed data from a national survey of endovascular training programs to assess the current training status and future projections. ...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Strozyk D,Hanft SJ,Kellner CP,Meyers PM,Lavine SD

    更新日期:2010-07-01 00:00:00

  • Normal Pressure Hydrocephalus and Parkinsonism: Preliminary Data on Neurosurgical and Neurological Treatment.

    abstract:OBJECTIVE:Idiopathic normal pressure hydrocephalus (iNPH) may present, besides the classic triad of symptoms, with extrapyramidal parkinsonianlike movement disorders. We present a randomized prospective study comparing adjustable ventriculoperitoneal (VP) shunt insertion plus dopamine oral therapy (group A) versus VP s...

    journal_title:World neurosurgery

    pub_type: 杂志文章,随机对照试验


    authors: Broggi M,Redaelli V,Tringali G,Restelli F,Romito L,Schiavolin S,Tagliavini F,Broggi G

    更新日期:2016-06-01 00:00:00

  • The role of endoscopic third ventriculostomy in the treatment of communicating hydrocephalus.

    abstract:OBJECTIVE:To elucidate the role of endoscopic third ventriculostomy (ETV) in patients with secondary and idiopathic communicating hydrocephalus (HCP). METHODS:A series of 36 patients with communicating HCP (21 men and 15 women) were treated by ETV between November 2007 and February 2010. The patients age ranged from 1...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Rangel-Castilla L,Barber S,Zhang YJ

    更新日期:2012-03-01 00:00:00

  • Quo vadis, academia? Can academic neurosurgery be resurrected?

    abstract::Clinical neurosurgery is an endangered academic discipline. Neurosurgeons have competition from many directions: orthopedists, ear, nose and throat surgeons, plastic surgeons, radio-oncologists, and interventional radiologists, among others. Academic centers are no longer the only sites of neurosurgical education at t...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Kasper EM,Fischer EG,Ostertag CB

    更新日期:2012-07-01 00:00:00

  • Pipeline Embolization of Vertebrobasilar Aneurysms-A Multicenter Case Series.

    abstract:BACKGROUND:The Pipeline Embolization Device (PED) has been increasingly used for the treatment of posterior circulation aneurysms. The purpose of the present study was to examine the clinical and angiographic outcomes of patients with vertebrobasilar aneurysms treated with the PED. METHODS:We performed a retrospective...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Wallace AN,Madaelil TP,Kamran M,Miller TR,Delgado Almandoz JE,Grossberg JA,Kansagra AP,Gandhi D,Kayan Y,Cawley CM,Moran CJ,Jindal G,CreveCoeur T,Howard BM,Cross DT,Kole MJ,Roy AK,Dion JE,Osbun JW

    更新日期:2019-01-03 00:00:00

  • Multimodal Management of Metastatic Malignant Meningiomas: The Role of Radiosurgery in Long-Term Local Control.

    abstract:BACKGROUND:Metastatic meningiomas (MMs) are rare (0.1 of 100 cases). Their treatment requires a multimodal approach, with surgery, radiotherapy, chemotherapy, and radiosurgery, which allows a long-term local control (LC) and an extension of free survival. In this study, the authors performed a review of the literature ...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Attuati L,Zaed I,Morselli C,Pecchioli G,Fornari M,Picozzi P

    更新日期:2019-08-01 00:00:00

  • Surgical options in treating Ossification of the Posterior Longitudinal Ligament (OPLL): a single center experience.

    abstract:BACKGROUND:Ossified posterior longitudinal ligament (OPLL) of the cervical spine can lead to spinal stenosis and become clinically symptomatic. The optimal approach in addressing OPLL is a debated topic and dependent on factors such as preoperative lordosis and levels affected. METHODS:In this study, we retrospectivel...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Park BJ,Seaman SC,Woodroffe RW,Noeller Arnp J,Hitchon PW

    更新日期:2021-01-19 00:00:00

  • Microsurgical Clipping of Low-Riding Basilar Bifurcation Aneurysm.

    abstract::Basilar bifurcation is a challenging site for aneurysm clipping. Anatomical factors such as size and projection of the aneurysm, distance between the aneurysm neck and the dorsum sellae, and location of the basilar bifurcation contribute to surgical complexity. Endovascular treatment has been used more frequently than...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Wainberg RC,da Costa MDS,Marchiori M,Soder RB,de Campos Filho JM,Netto HLD,Neto EP,Chaddad-Neto F

    更新日期:2018-12-31 00:00:00

  • The Lumbosacral Dural Venous Sinus: A New Discovery with Potential Clinical Applications.

    abstract:BACKGROUND:Traditionally, the dural venous sinuses have been described only in the cranium. However, anecdotally, during various neurosurgical intradural procedures in the lumbosacral spine, we noticed an intradural collection of blood. With no prior studies on this in the extant medical literature, the following anato...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Iwanaga J,Alonso F,Akobo S,Turgut M,Yurttas C,Loukas M,Reina MA,Oskouian RJ,Tubbs RS

    更新日期:2017-05-01 00:00:00

  • The Value and Limitation of Cervical Traction in the Evaluation of the Reducibility of Atlantoaxial Dislocation and Basilar Invagination Using the Intraoperative O-Arm.

    abstract:OBJECTIVE:To assess the value and limitation of cervical traction in the evaluation of the reducibility of atlantoaxial dislocation (AAD) and basilar invagination (BI) using the intraoperative O-arm. METHODS:A total of 22 patients with hyperextensive, irreducible AAD were included. The cervical traction test under gen...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Duan W,Du Y,Qi T,Jiang B,Wang K,Liu Z,Guan J,Wang X,Wu H,Chen Z,Jian F

    更新日期:2019-12-01 00:00:00

  • Management of Venous Sinus-Related Epidural Hematomas.

    abstract:BACKGROUND:Epidural hematomas (EDHs) involving the venous sinuses are uncommon and carry the risk of hemorrhage or venous infarction. We report the largest case series for superior sagittal sinus- and transverse sinus-related EDHs including surgical and nonsurgical management. We compare our findings to the relevant li...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Parker SL,Kabani AA,Conner CR,Choi PA,Withrow JS,Cai C,Kitagawa RS

    更新日期:2020-06-01 00:00:00

  • Can Fan-Beam Interactive Computed Tomography Accurately Predict Indirect Decompression in Minimally Invasive Spine Surgery Fusion Procedures?

    abstract:BACKGROUND:Recently, novel mobile intraoperative fan-beam computed tomography (CT) was introduced, allowing for real-time navigation and immediate intraoperative evaluation of neural decompression in spine surgery. This study sought to investigate whether intraoperatively assessed neural decompression during minimally ...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Janssen I,Lang G,Navarro-Ramirez R,Jada A,Berlin C,Hilis A,Zubkov M,Gandevia L,Härtl R

    更新日期:2017-11-01 00:00:00

  • Isolated Trochlear Nerve Palsy in a Patient with Superior Cerebellar Rete Mirabile.

    abstract:BACKGROUND:Rete mirabile is a very rare vascular malformation and superior cerebellar artery (SCA) rete mirabile is not reported previously. We report a new case of rete mirabile of SCA initially detected by magnetic resonance imaging and transfemoral cerebral angiography. CASE DESCRIPTION:This report illustrates the ...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Shin Y,Lee KM,San Lee J,Kim EJ,Kim HG,Yeon EK

    更新日期:2019-10-01 00:00:00

  • Atlantoaxial Fixation for Odontoid Fracture: Analysis of 124 Surgically Treated Cases.

    abstract:OBJECTIVE:The authors analyze 124 cases with fracture of odontoid process. All patients were surgically treated by posterior atlantoaxial fixation. METHODS:There were 96 male and 28 female patients. The ages of the patients ranged from 12 to 80 years. Apart from Anderson and D'Alonzo type I (6 cases), type II (93 case...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Goel A,Jain S,Shah A,Patil A,Vutha R,Ranjan S,More S

    更新日期:2018-02-01 00:00:00

  • Surgical microanatomy of the anterior clinoid process for paraclinoid aneurysm surgery and efficient modification of extradural anterior clinoidectomy.

    abstract:BACKGROUND:Anatomic variations of the anterior clinoid process (ACP) should be recognized before clinoidectomy to ensure a safe approach. This study describes the incidence of caroticoclinoid foramen (CCF), interclinoid osseous bridge, and pneumatization of the ACP during extradural anterior clinoidectomy. The problems...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Ota N,Tanikawa R,Miyazaki T,Miyata S,Oda J,Noda K,Tsuboi T,Takeda R,Kamiyama H,Tokuda S

    更新日期:2015-04-01 00:00:00

  • Long-term outcomes of ventriculoperitoneal shunt surgery in patients with hydrocephalus.

    abstract:OBJECTIVE:Ventriculoperitoneal (VP) shunt surgery is the predominant mode of therapy for patients with hydrocephalus. However, it has potential complications that may require multiple surgical procedures during a patient's lifetime. The objective of this study is to review our long-term experience and evaluate the risk...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Reddy GK,Bollam P,Caldito G

    更新日期:2014-02-01 00:00:00

  • A Practical Cadaveric Model for Intracranial Bypass Training.

    abstract:BACKGROUND:Intracranial bypass is technically challenging and difficult to learn owing to its relative rarity and complexity. Although multiple training models for intracranial bypass exist, a detailed depiction of the use and fidelity of cadaveric specimens for bypass training is lacking in the literature. This study ...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Steinberg JA,Rennert RC,Levy M,Khalessi AA

    更新日期:2019-01-01 00:00:00

  • Percutaneous Full-Endoscopic Anterior Transcorporeal Diskectomy for Massive Migrated Cervical Disk Herniation Treatment: Case Report and Review of the Literature.

    abstract:BACKGROUND:With the continuous advancement of the spinal endoscopic technique in recent years, full-endoscopic operations provide a new approach for the treatment of migrated cervical disk herniation. CASE DESCRIPTION:A 42-year-old man presented with nuchal pain and limb numbness for 2 months, with recently developed ...

    journal_title:World neurosurgery

    pub_type: 杂志文章,评审


    authors: Qiao Y,Liao WB,Du Q,Ao J,Cai YQ,Kong WJ,Qin J

    更新日期:2019-12-01 00:00:00

  • In-Hospital Complications and Resource Utilization Following Lumbar Spine Surgery in Patients with Parkinson Disease: Evaluation of the National Inpatient Sample Database.

    abstract:BACKGROUND:Previous reports suggest that patients with Parkinson disease (PD) have elevated rates of complications following spine surgery; however, these reports are limited by small patient series. In this study, we used the National Inpatient Sample (NIS) database to compare in-hospital complications following elect...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Baker JF,McClelland S 3rd,Line BG,Smith JS,Hart RA,Ames CP,Shaffrey C,Bess S

    更新日期:2017-10-01 00:00:00

  • Choroidal fissure cerebrospinal fluid-containing cysts: case series, anatomical consideration, and review of the literature.

    abstract:BACKGROUND:Cerebrospinal fluid (CSF)-containing cysts at the level of the choroidal fissure are rare embryological entities infrequently described in the literature because of their benign nature. On the occasion of a case series, we present an overview of the literature and discuss anatomical and embryological locatio...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: de Jong L,Thewissen L,van Loon J,Van Calenbergh F

    更新日期:2011-05-01 00:00:00

  • Intervertebral Displacement of the Thoracic Spine with and without Loading: Radiographic and in Vitro Measurements.

    abstract:BACKGROUND:We are developing an intradural approach to spinal cord stimulation, where the thin electrode array is affixed stably to the underside of the thoracic spinal dura mater without leakage of cerebrospinal fluid. As part of the design and testing process, we sought to evaluate the potential risk of inadvertent c...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Seaman SC,Zanaty M,Holland MT,Gillies GT,Howard MA 3rd,Yamaguchi S

    更新日期:2020-06-01 00:00:00

  • Hippocampal Transection Plus Tumor Resection as a Novel Surgical Treatment for Temporal Lobe Epilepsy Associated with Cerebral Cavernous Malformations.

    abstract:OBJECTIVE:The optimal surgical treatment for cavernous malformation-related temporal lobe epilepsy (CRTLE) is still controversial because it frequently involves the hippocampus as an epileptogenic zone. Here we describe our unique surgical strategy of performing hippocampal transection (HT) plus tumor resection for CRT...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Ishida W,Morino M,Matsumoto T,Casaos J,Ramhmdani S,Lo SL

    更新日期:2018-11-01 00:00:00

  • Direct C2 Pedicle Screw Fixation for Axis Body Fracture.

    abstract:BACKGROUND:Acute complex C2 vertebral body fracture specifically does not involve the odontoid process or C2 pars interarticularis. External stabilization can be effective but may prolong healing and increase morbidity. Many traditional surgical techniques can achieve internal stabilization at the expense of normal cer...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Reynolds JA,MacDonald JD

    更新日期:2016-09-01 00:00:00

  • Feasibility of High-Resolution 3-Dimensional Sampling Perfection with Application-Optimized Contrast Using Different Flip Angle Evolution Imaging for the Preoperative Detection of Parasinus Meningioma: A Pilot Study Compared with Contrast-Enhanced Magneti

    abstract:OBJECTIVES:To prospectively evaluate the diagnostic value of 3.0 Tesla magnetic resonance 3-dimensional sampling perfection with application-optimized contrast using different flip angle evolution (3D-SPACE) in the detection of sinus wall invasion and sinus patency in parasinus meningiomas. METHODS:In this study, 28 p...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Tianfang Y,Liang X,Yukui W,Qingtang L,Liqun J,Geng X

    更新日期:2018-11-01 00:00:00

  • COVID-19: Launching Neurosurgery into the Era of Telehealth in the United States.

    abstract::The authors discuss the implications of the COVID-19 pandemic on the use of telehealth in the United States. ...

    journal_title:World neurosurgery

    pub_type: 杂志文章,评审


    authors: Wright CH,Wright J,Shammassian B

    更新日期:2020-08-01 00:00:00

  • Role of Endoscopic Third Ventriculostomy in the Management of Myelomeningocele-Related Hydrocephalus: A Retrospective Study in a Single French Institution.

    abstract:INTRODUCTION:Treatment of hydrocephalus related to myelomeningocele (MM) is debated. Endoscopic third ventriculostomy (ETV) has been proposed with contrasting results. We report our experience in the management of hydrocephalus related to MM and the advantages of ETV. MATERIAL AND METHODS:From 1994 to 2012, we treated...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Beuriat PA,Szathmari A,Grassiot B,Plaisant F,Rousselle C,Mottolese C

    更新日期:2016-03-01 00:00:00

  • Treatment of Extracranial Vertebral Artery Aneurysm with Flow Diversion.

    abstract:BACKGROUND:Aneurysms of the extracranial vertebral artery are rare, and the treatment options are not standardized. We present a case of an extracranial vertebral artery aneurysm treated with flow diversion. CASE DESCRIPTION:In a 72-year-old woman, computed tomography angiography demonstrated a right extracranial vert...

    journal_title:World neurosurgery



    authors: Wu H,Wang M,Li K,Wang F

    更新日期:2020-06-01 00:00:00

  • The Vertebral Artery Cave at C2: Anatomic Study with Application to C2 Pedicle Screw Placement.

    abstract:OBJECTIVE:Knowledge of the course of the vertebral artery during instrumentation is of paramount importance. It has been shown that erosion of the C2 pedicle and body can occur due to pulsations of the adjacent vertebral artery. This often results in a "cave" for this segment of the artery. The descriptions of this ana...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Tubbs RS,Granger A,Fisahn C,Loukas M,Moisi M,Iwanaga J,Paulson D,Jeyamohan S,Chapman JR,Oskouian RJ

    更新日期:2016-10-01 00:00:00