Prognostic value of ATAD3 gene cluster expression in hepatocellular carcinoma.

abstract：:Metastatic spread of gastric carcinoma to the breast is rare. In previous decades, reports on this subject were minimal and primarily limited to case reports. At present, little is known on the clinicopathological features and prognosis of this condition, and breast metastasis remains a challenging clinical problem. A...

journal_title：Oncology letters

authors： Ma Y,Liu W,Li J,Xu Y,Wang H

更新日期：2018-11-01 00:00:00

abstract：:Transforming growth factor β (TGFβ) ligands, including TGFβ1, are multifunctional cytokines known as key regulators of cell growth, differentiation and inflammation. Dysregulated TGFβ signaling is common in numerous solid tumors, including head and neck squamous cell carcinoma (HNSCC). Previously, TGFβ ligands were al...

journal_title：Oncology letters

authors： Bae WJ,Lee SH,Rho YS,Koo BS,Lim YC

更新日期：2016-12-01 00:00:00

abstract：:Cancer stem cells (CSCs), defined by CD133 expression, harbor heterogeneous subpopulations of cells, including endothelial progenitor cells (EPCs). This study aimed to investigate whether a subpopulation of CSCs could affect the radiographic characteristics of glioblastoma. Tissue samples from 10 patients newly diagno...

journal_title：Oncology letters

authors： Kim JE,Kim SK,Shin J,Se YB,Choi SH,Park SH,Choi SA,Lee JY,Phi JH,Wang KC,Park CK,Kim SK

更新日期：2017-03-01 00:00:00

abstract：:Chronic myelogenous leukemia (CML) is a common hematological malignancy. Some patients progressing to the blast phase develop chemotherapeutic drug resistance. In the authors' previous study, it was found that the mammalian target of rapamycin (mTOR) pathway was activated in CML and that rapamycin inhibited the prolif...

journal_title：Oncology letters

authors： Li J,Liu W,Hao H,Wang Q,Xue L

更新日期：2019-09-01 00:00:00

abstract：:Chromodomain helicase DNA-binding 5 (CHD5), which is a member of the CHD family, has been identified as a tumor suppressor gene in a variety of malignancies. The aim of the current study was to clarify the clinical significance of CHD5 expression in gastric cancer. CHD5 expression was evaluated using immunohistochemis...

journal_title：Oncology letters

authors： Hashimoto T,Kurokawa Y,Wada N,Takahashi T,Miyazaki Y,Tanaka K,Makino T,Yamasaki M,Nakajima K,Mori M,Doki Y

更新日期：2020-01-01 00:00:00

abstract：:Curcumin is a non-nutritive yellow pigment found in the spice turmeric, which is derived from the rhizome of the plant Curcuma longa Linn. Six cyclohexanone analogues of curcumin (A(1)-A(6)) were investigated for their effects on growth and apoptosis in PC-3 human prostate cancer cells. The ability of these compounds ...

journal_title：Oncology letters

authors： Wei X,DU ZY,Cui XX,Verano M,Mo RQ,Tang ZK,Conney AH,Zheng X,Zhang K

更新日期：2012-08-01 00:00:00

abstract：:Patients with non-platinum-sensitive recurrent ovarian cancer have a poor prognosis. Non-pegylated liposomal doxorubicin (Myocet®) is a promising drug that may be able to improve treatment for such patients. In the current study, patients with recurrent ovarian cancer relapsing within 12 months after primary treatment...

journal_title：Oncology letters

authors： Brucker J,Mayer C,Gebauer G,Mallmann P,Belau AK,Schneeweiss A,Sohn C,Eichbaum M

更新日期：2016-08-01 00:00:00

abstract：:The present study aimed to evaluate the expression of hypoxia-inducible factor-1α (HIF-1α) and MDR1/P-glycoprotein (P-gp) in human laryngeal squamous cell carcinoma (LSCC) tissues, and also to investigate the regulation of MDR1 gene expression by HIF-1α in Hep-2 cells under hypoxic conditions. The expression of HIF-1α...

journal_title：Oncology letters

authors： Xie J,Li DW,Chen XW,Wang F,Dong P

更新日期：2013-07-01 00:00:00

abstract：:The aim of the present study was to analyze potential therapy targets for prostate cancer using integrated analysis of two gene expression profiles. First, gene expression profiles GSE38241 and GSE3933 were downloaded from the Gene Expression Omnibus database. Differentially expressed genes (DEGs) between prostate can...

journal_title：Oncology letters

authors： Zhao R,Wang Y,Zhang M,Gu X,Wang W,Tan J,Wei X,Jin N

更新日期：2017-11-01 00:00:00

abstract：:The occurrence of primary carcinoma of the ureteral stump following radical nephrectomy for renal cell carcinoma is extremely rare; 7 patients with the disease have been reported previously. All these patients were males with transitional cell carcinoma. The current study reports the case of a 61-year-old woman, who p...

journal_title：Oncology letters

authors： Jin S,Wang G,Yu C,Li N

更新日期：2016-05-01 00:00:00

abstract：:Fluoro-edenite is a natural mineral species initially isolated in Biancavilla, Sicily. The fibres are similar in size and morphology to certain amphibolic asbestos fibres, the inhalation of which may cause chronic inflammation and cancer. Occupational asbestos exposure is known to be associated with pleural and lung d...

journal_title：Oncology letters

authors： Rapisarda V,Ledda C,Ricceri V,Arena F,Musumeci A,Marconi A,Fago L,Bracci M,Santarelli L,Ferrante M

更新日期：2015-05-01 00:00:00

abstract：:Decreased expression of ten-eleven translocation (TET1, TET2 and TET3) proteins has been reported in various types of cancer. However, the expression levels of TET proteins in cervical cancer (CC) remain to be elucidated. The present study determined the levels of TET1, TET2 and TET3 transcripts in cancerous (n=80) an...

journal_title：Oncology letters

authors： Bronowicka-Kłys DE,Roszak A,Pawlik P,Sajdak S,Sowińska A,Jagodziński PP

更新日期：2017-05-01 00:00:00

abstract：:Ganglioneuromas (GNs) arising from neural crest sympathogonia are rare benign neurogenic tumors. The most commonly affected sites are the posterior mediastinum, the retroperitoneum and the adrenal gland. GNs often present as a solitary, painless and slow-growing mass, and multiple occurrences in the cervical region ar...

journal_title：Oncology letters

authors： Ma J,Liang L,Liu H

更新日期：2012-09-01 00:00:00

abstract：:Colorectal cancer (CRC) is one of the leading causes of mortality among men and women. Chemo-resistance, adverse effects and disease recurrence are major challenges in the development of effective cancer therapeutics. Substantial literature on this subject highlights that populations consuming diets rich in fibers, fr...

journal_title：Oncology letters

authors： Ahmed K,Zaidi SF,Cui ZG,Zhou D,Saeed SA,Inadera H

更新日期：2019-07-01 00:00:00

abstract：:Xeroderma pigmentosum group C (XPC) is a DNA-damage-recognition gene active at the early stage of DNA repair. XPC also participates in regulation of cell-cycle checkpoint and DNA-damage-induced apoptosis. In the present study, the expression levels of genes involved in nucleotide excision repair (NER) were assessed in...

journal_title：Oncology letters

authors： Zhang Y,Cao J,Meng Y,Qu C,Shen F,Xu L

更新日期：2018-05-01 00:00:00

abstract：:Induction of apoptosis in human cancer cells by Sasa quelpaertensis Nakai has been considered to be a potential therapeutic target for cancer treatment; however, the underlying mechanisms of action are not well understood. The present study investigated the role of nitric oxide (NO•) and inhibitors of apoptosis (IAPs)...

journal_title：Oncology letters

authors： Kim MY

更新日期：2020-04-01 00:00:00

abstract：:Tanshinone IIA exhibits natural antioxidative and antineoplastic activity. However, to the best of our knowledge, the effects of tanshinone IIA on human nasopharyngeal carcinoma cells remains unknown. The present study aimed to investigate whether tanshinone IIA inhibits proliferation and induces apoptosis of human na...

journal_title：Oncology letters

authors： Liu B,Liu L,Zang A,Song Z,Yang H,Wang Z,Shang Y,Ma T,Zhang Y

更新日期：2019-09-01 00:00:00

abstract：:The aim of the present study was to examine the interrelations between MEG-A3 gene and incidence of breast cancer. The expression of MEG-A3 gene in the tissue samples of patients with breast cancer and normal controls at RNA and protein levels was determined. Subsequently, the relative expression of RNA for the same p...

journal_title：Oncology letters

authors： Hou X,Guo F,Sun Q

更新日期：2016-12-01 00:00:00

abstract：:Factor that binds to the inducer of short transcripts of the human immunodeficiency virus-1 (FBI-1) represents as a crucial gene regulator in colorectal cancer; however, the correlation between FBI-1 and preoperative radiotherapy (RT) in rectal cancer (RC) has not yet been reported. The aim was to detect FBI-1 express...

journal_title：Oncology letters

authors： Wang CJ,Chao CR,Liu HM,Zhu YY,Adell G,Jarlsfelt I,Zhang H,Sun XF

更新日期：2019-11-01 00:00:00

abstract：:The present study aimed to ascertain whether suppression of midkine (MK) expression in pancreatic cancer cells inhibits metastasis to the liver. Human pancreatic cancer AsPC-1 cells were transfected with small interfering RNA (siRNA) targeting MK. siRNA against MK was observed to reduce the expression of MK mRNA and p...

journal_title：Oncology letters

authors： Yu L,Fan Y,Chen B,Hu Y,Gao Y,Wei D

更新日期：2013-11-01 00:00:00

abstract：:Cross-talk between competing endogenous RNAs (ceRNAs) play key roles in tumor development. In this study, we performed exon-level expression profiling on 26 glioblastomas (GBMs) and 6 controls to identify long non-coding RNAs (lncRNAs) of GBM initiation and progression using lncRNA-mediated ceRNA network (LMCN). The m...

journal_title：Oncology letters

authors： Zan XY,Li L

更新日期：2019-05-01 00:00:00

abstract：:Chronic hepatitis B virus (HBV) is the leading cause of hepatocellular carcinoma (HCC). Covalently closed circular DNA (cccDNA) is an intermediate in the life cycle of HBV. HBV-encoded X protein (HBx), a key viral oncoprotein, can be specifically ubiquitylated by male specific lethal 2 (MSL2), which causes upregulatio...

journal_title：Oncology letters

authors： Jin XL,Hong SK,Kim H,Lee SK,Yi NJ,Lee KW,Suh KS

更新日期：2019-11-01 00:00:00

abstract：:It has been demonstrated that microRNA-497 (miR-497) acts as a tumor suppressor and is involved in tumor progression, development and metastasis in several types of cancer. However, little is known about the exact role of miR-497 in osteosarcoma (OS). The aim of the current study was to investigate the potential role ...

journal_title：Oncology letters

authors： Ge L,Zheng B,Li M,Niu L,Li Z

更新日期：2016-03-01 00:00:00

abstract：:Clinical evidence indicates that drug resistance is a major obstacle in the treatment of breast cancer (BC). Drug resistance results in the disease being uncontrollable, and leads to high mortality rates. The aim of the present study was to investigate the chemosensitizing effect of microRNA (miR)-16 on Adriamycin (AD...

journal_title：Oncology letters

authors： Gao X,Wang M,Zhang Y,Xu Z,Ding J,Tang J

更新日期：2019-09-01 00:00:00

abstract：:This study aimed to investigate the correlation between the expression of CD24 and B7-H3 in breast cancer tissues and the clinical significance. Expression of CD24 and B7-H3 in breast cancer and adjacent tissues were detected by immunohistochemistry. Quantitative PCR was used to detect the expression of CD24 and B7-H3...

journal_title：Oncology letters

authors： Cong F,Yu H,Gao X

更新日期：2017-12-01 00:00:00

abstract：:Pancreatic cancer has a low survival rate globally. Anillin (ANLN) is involved in the pathogenesis of pancreatic cancer (PC). The present study used databases and reverse transcription-quantitative PCR to investigate the association between ANLN expression, clinical variables and the survival rate of patients with pan...

journal_title：Oncology letters

authors： Nie Y,Zhao Z,Chen M,Ma F,Fan Y,Kang Y,Kang B,Wang C

更新日期：2021-02-01 00:00:00

abstract：:Esophageal cancer staging is important for the treatment of esophageal cancer. Endoscopic ultrasonography (EUS) is a common diagnostic tool for esophageal cancer prior to surgery. However, EUS is unable to accurately discriminate the N-staging of lymph nodes. In order to distinguish an optimized standard for malignant...

journal_title：Oncology letters

authors： Zhang Y,He S,Dou L,Liu Y,Ke Y,Yu X,Wang Z,Wang G

更新日期：2019-01-01 00:00:00

abstract：:Little information from clinical trials is available regarding the efficacy of trastuzumab treatment in subcentimetric breast carcinomas (BCs). The aim of this study was to verify the existence of correlations between HER2 and hormone receptor status, Ki67 values, grade, histotype and node involvement in a cohort of p...

journal_title：Oncology letters

authors： Ieni A,Giuffrè G,Lanzafame S,Nuciforo G,Curduman M,Villari L,Roz E,Certo G,Cabibi D,Salomone E,Labate A,Messina D,Franco V,Adamo V,Tuccari G

更新日期：2012-01-01 00:00:00

abstract：:Breast cancer is the most common malignant tumor in women in the majority of countries, such as China, Britain and Australia, and its morbidity and mortality rates remain very high. Long non-coding RNAs (lncRNAs) are non-coding RNAs (ncRNAs) >200 nucleotides in length that lack open reading frames. LncRNA H19 is a tra...

journal_title：Oncology letters

authors： Wang J,Sun J,Yang F

更新日期：2020-01-01 00:00:00

abstract：:Endometrial cancer (EC) is the most commonly diagnosed gynecological malignancy in Australian women. Notably, its incidence and mortality rate is increasing. Despite this, there are limited treatment options for EC. Galectin-7 regulates tumorigenesis in numerous epithelial cancer types, but the role of galectin-7 has ...

journal_title：Oncology letters

authors： Menkhorst E,Griffiths M,Van Sinderen M,Rainczuk K,Niven K,Dimitriadis E

更新日期：2018-10-01 00:00:00