Application of Biomarker Tools Using Bivalve Models Toward the Development of Adverse Outcome Pathways for Contaminants of Emerging Concern.

abstract：:Diluted bitumen (dilbit; the product of oil sands extraction) is transported through freshwater ecosystems critical to Pacific salmon. This is concerning, because crude oil disrupts cardiac development, morphology, and function in embryonic fish, and cardiac impairment in salmon can have major consequences on migrator...

journal_title：Environmental toxicology and chemistry

authors： Alderman SL,Lin F,Farrell AP,Kennedy CJ,Gillis TE

更新日期：2017-02-01 00:00:00

abstract：:The influence of diet on polychlorinated biphenyl (PCB) assimilation was investigated by measuring dietary assimilation efficiencies (AEs) for 47 PCB congeners in juvenile koi (Cyprinus carpio) fed five experimental diets. Two of the diets were naturally contaminated and were obtained by collecting mayflies from Lake ...

journal_title：Environmental toxicology and chemistry

authors： Liu J,Haffner GD,Drouillard KG

更新日期：2010-02-01 00:00:00

abstract：:Extensive agricultural use of neonicotinoid insecticide products has resulted in the presence of neonicotinoid mixtures in surface waters worldwide. Although many aquatic insect species are known to be sensitive to neonicotinoids, the impact of neonicotinoid mixtures is poorly understood. In the present study, the cum...

journal_title：Environmental toxicology and chemistry

authors： Maloney EM,Morrissey CA,Headley JV,Peru KM,Liber K

更新日期：2017-11-01 00:00:00

abstract：:Northern leopard frogs (Rana pipiens) have been disappearing throughout their range. The causes for extirpations have been elusive, although habitat alteration appears to be a major factor. Pesticides have been implicated in declines in western amphibians, but no mechanism has been identified. We tested the hypothesis...

journal_title：Environmental toxicology and chemistry

authors： Distel CA,Boone MD

更新日期：2011-03-01 00:00:00

abstract：:Understanding the environmental risks of pharmaceuticals and personal care products (PPCPs) has become very important in the field of aquatic toxicology. Hydroxylpropyl-β-cyclodextrin (HPβCD) is an amphiphilic, toroidal shaped molecule with the ability to form noncovalent inclusion complexes with a variety of guest mo...

journal_title：Environmental toxicology and chemistry

authors： Anderson JC,Beyger L,Guchardi J,Holdway D

更新日期：2016-06-01 00:00:00

abstract：:Exposure to agrochemicals in the aquatic environment often occurs as time-varying or repeated pulses. Time-varying exposures may occur due to runoff events and spray drift associated with precipitation and application events. Hydrologic dilution, dispersion, and degradation also produce pulsed exposures. Standard labo...

journal_title：Environmental toxicology and chemistry

authors： Reinert KH,Giddings JM,Judd L

更新日期：2002-09-01 00:00:00

abstract：:The present study examined the relative importance of copper (aqueous Cu and CuO particles of different sizes) added to sediment to determine the bioaccumulation, toxicokinetics, and effects in the deposit feeder Potamopyrgus antipodarum. In experiment 1, the bioaccumulation of Cu (240 µg Cu/g dry wt of sediment) adde...

journal_title：Environmental toxicology and chemistry

authors： Pang C,Selck H,Banta GT,Misra SK,Berhanu D,Dybowska A,Valsami-Jones E,Forbes VE

更新日期：2013-07-01 00:00:00

abstract：:Methylmercury is a globally distributed neurotoxin, endocrine disruptor, and teratogen, the effects of which on wildlife at environmentally relevant levels are largely unknown. In birds, foraging efficiency and learning may be sensitive endpoints for sublethal methylmercury toxicity, and these endpoints also may be bi...

journal_title：Environmental toxicology and chemistry

authors： Adams EM,Frederick PC

更新日期：2008-08-01 00:00:00

abstract：:In vitro metabolic stability assays using rainbow trout (Oncorhynchus mykiss) isolated hepatocytes (RT-HEP) or hepatic S9 fractions (RT-S9) were introduced to provide biotransformation rate data for the assessment of chemical bioaccumulation in fish. The present study explored the suitability of the RT-HEP and RT-S9 a...

journal_title：Environmental toxicology and chemistry

authors： Kropf C,Begnaud F,Gimeno S,Berthaud F,Debonneville C,Segner H

更新日期：2020-12-01 00:00:00

abstract：:Recently it was discovered that the perfluorooctane sulfonate (PFOS) detected in wildlife, such as fish-eating birds, had a greater proportion of linear PFOS (L-PFOS) than the manufactured technical product (T-PFOS), which contains linear and branched isomers. This suggests toxicological studies based on T-PFOS data m...

journal_title：Environmental toxicology and chemistry

authors： O'Brien JM,Austin AJ,Williams A,Yauk CL,Crump D,Kennedy SW

更新日期：2011-12-01 00:00:00

abstract：:The effects of antidepressants on wildlife are currently raising some concern because of an increased number of publications indicating biological effects at environmentally relevant concentrations (<100 ng/L). These results have been met with some scepticism because of the higher concentrations required to detect eff...

journal_title：Environmental toxicology and chemistry

authors： Ford AT,Fong PP

更新日期：2016-04-01 00:00:00

abstract：:A method is proposed for estimating metabolic biotransformation rate constants for nonionic organic chemicals from measured laboratory bioconcentration and dietary bioaccumulation data in fish. Data have been selected based on a quality review to reduce uncertainty in the measured values. A kinetic mass balance model ...

journal_title：Environmental toxicology and chemistry

authors： Arnot JA,Mackay D,Bonnell M

更新日期：2008-02-01 00:00:00

abstract：:We raised embryos and tadpoles of green frogs (Rana clamitans melanota) and leopard frogs (R. pipiens) in situ along a contamination gradient in the Fox River/Green Bay ecosystem (WI, USA). Differences in exposure were reflected by significant positive regressions between concentrations in sediment and in frogs of pol...

journal_title：Environmental toxicology and chemistry

authors： Karasov WH,Jung RE,Langenberg SV,Bergeson TL

更新日期：2005-04-01 00:00:00

abstract：:Potassium permanganate (KMnO4) is used worldwide in freshwater pond aquaculture for treatment and prevention of waterborne external parasitic, bacterial, and fungal diseases. Nevertheless, KMnO4 has not been approved by the U.S. Food and Drug Administration, and insufficient information exists to allow evaluation of t...

journal_title：Environmental toxicology and chemistry

authors： Hobbs MS,Grippo RS,Farris JL,Griffin BR,Harding LL

更新日期：2006-11-01 00:00:00

abstract：:The Chemical Aquatic Fate and Effects (CAFE) database is a centralized repository that allows for rapid and unrestricted access to data. Information in CAFE is integrated into a user-friendly tool with modules containing fate and effects data for 32 377 and 4498 chemicals, respectively. Toxicity data are summarized in...

journal_title：Environmental toxicology and chemistry

authors： Bejarano AC,Farr JK,Jenne P,Chu V,Hielscher A

更新日期：2016-06-01 00:00:00

abstract：:Most of the public literature and available guidance documents on the conduct of freshwater whole-sediment toxicity identification and evaluations (TIEs) detail the use of test organisms and amending agents that are readily available in North America. These commonly used test organisms and the supported amending agent...

journal_title：Environmental toxicology and chemistry

authors： Mehler WT,Keough MJ,Pettigrove V

更新日期：2017-09-01 00:00:00

abstract：:The aim of the present study was to assess the responses of the gonopodium morphology and the gonadal and liver histology of adult male Cnesterodon decemmaculatus to sublethal long-term exposure concentrations of 17α-ethinylestradiol (EE2). Two experiments were conducted exposing the fish to waterborne concentrations ...

journal_title：Environmental toxicology and chemistry

authors： Young BJ,López GC,Cristos DS,Crespo DC,Somoza GM,Carriquiriborde P

更新日期：2017-07-01 00:00:00

abstract：:The fish plasma model (FPM) predicts the fish blood plasma concentration of a pharmaceutical from the water concentration to which the fish is exposed and compares it with the human therapeutic plasma concentration (Hther PC) with the postulate that no adverse toxic effects occur below the Hther PC. The present study ...

journal_title：Environmental toxicology and chemistry

authors： Weil M,Falkenhain AM,Scheurer M,Ryan JJ,Coors A

更新日期：2019-11-01 00:00:00

abstract：:The major toxaphene metabolites in sediment and soils (2-exo,3-endo,6-exo,8,9,10-hexachlorobornane [B6-923] and 2-endo,3-exo,5-endo,6-exo,8,9,10-heptachlorobornane [B7-1001]) were incubated with the isolated gram-negative bacterium Dehalospirillum multivorans. Within 14 d, biotransformation of B7-1001 was nearly quant...

journal_title：Environmental toxicology and chemistry

authors： Ruppe S,Neumann A,Braekevelt E,Tomy GT,Stern GA,Maruya KA,Vetter W

更新日期：2004-03-01 00:00:00

abstract：:Marine waters have been poorly investigated for the occurrence of pharmaceutical contamination. Recent data confirm that pharmaceuticals occur widely in marine and coastal environments; therefore, assessment of potential risk to marine species needs further efforts. The present study represents the first extensive rev...

journal_title：Environmental toxicology and chemistry

authors： Fabbri E,Franzellitti S

更新日期：2016-04-01 00:00:00

abstract：:A Unit World approach has been used extensively to rank chemicals for their hazards and to understand differences in chemical behavior. Whereas the fate and effects of an organic chemical in a Unit World Model (UWM) analysis vary systematically according to one variable (fraction of organic carbon), and the chemicals ...

journal_title：Environmental toxicology and chemistry

authors： Gandhi N,Bhavsar SP,Diamond ML

更新日期：2011-09-01 00:00:00

abstract：:The majority of studies on pesticide impacts have evaluated the effects of single exposures. However, multiple exposures to a pesticide may be more prevalent. The objective of our study was to determine how multiple exposures versus single exposure at different times during development affected survival to metamorphos...

journal_title：Environmental toxicology and chemistry

authors： Boone MD,Bridges CM

更新日期：2003-11-01 00:00:00

abstract：:This study was designed to investigate whether or not chronic exposure to Chornobyl radiation poses a molecular genetic risk to mammals by examining a relatively rapidly evolving genetic system, mitochondrial DNA (mtDNA). More mtDNA mutations (approximately 19%) and an increase in mtDNA heteroplasmy (approximately 5%)...

journal_title：Environmental toxicology and chemistry

authors： Wickliffe JK,Chesser RK,Rodgers BE,Baker RJ

更新日期：2002-06-01 00:00:00

abstract：:Pyrethroids are insecticides widely used to control pests and disease vectors in residential areas and agricultural lands. Pyrethroids are emerging pollutants, and their use is a growing concern because of their toxicity potential to aquatic organisms. Todos Santos Bay and the Punta Banda estuary, 2 coastal bodies loc...

journal_title：Environmental toxicology and chemistry

authors： Hernández-Guzmán FA,Macías-Zamora JV,Ramírez-Álvarez N,Alvarez-Aguilar A,Quezada-Hernández C,Fonseca AP

更新日期：2017-11-01 00:00:00

abstract：:The present study evaluated the effects of field metal contamination on sperm motility and the RNA/DNA ratio in echinoderms. Populations of Asterias rubens and Echinus acutus that occur naturally along a contamination gradient of sediments by cadmium, copper, lead, and zinc in a Norwegian fjord (the Sørfjord) were stu...

journal_title：Environmental toxicology and chemistry

authors： Catarino AI,Cabral HN,Peeters K,Pernet P,Punjabi U,Dubois P

更新日期：2008-07-01 00:00:00

abstract：:In the summary/recommendations for the Ecotoxicology Session of TestSmart--A Humane and Efficient Approach to Screening Information Data Sets (SIDS) Data Workshop, it was recommended that more population growth impairment data using Tetrahymena be generated and compared with available lethality data for the fathead mi...

journal_title：Environmental toxicology and chemistry

authors： Sinks GD,Schultz TW

更新日期：2001-04-01 00:00:00

abstract：:A theoretical analysis was performed to examine the role of naphthalene dioxygenase (NDO) enzymes in determining differences in biodegradability and biodegradation rates of two- to four-ring polycyclic aromatic hydrocarbons (PAHs) via oxygenation and desaturation reactions. Investigation of the thermodynamics of PAH b...

journal_title：Environmental toxicology and chemistry

authors： Wammer KH,Peters CA

更新日期：2006-04-01 00:00:00

abstract：:The ability of Spartina alterniflora to degrade tributyltin (TBT) in contaminated dredge spoils was investigated in a created wetland at Little Creek Naval Amphibious Base in Norfolk, Virginia, USA. Concentrations of TBT up to 250 ng/g did not inhibit S. alterniflora growth over a 16-month period. Disappearance rates ...

journal_title：Environmental toxicology and chemistry

authors： Anderson BA,Unger MA,Moore KA

更新日期：2002-06-01 00:00:00

abstract：:The influence of dissolved organic carbon (DOC) and water composition on the toxicity of copper to juvenile freshwater mussels (fatmucket, Lampsilis siliquoidea) were evaluated in natural and reconstituted waters. Acute 96-h copper toxicity tests werec onducted at four nominal DOC concentrations (0, 2.5, 5, and 10 mg/...

journal_title：Environmental toxicology and chemistry

authors： Wang N,Mebane CA,Kunz JL,Ingersoll CG,May TW,Arnold WR,Santore RC,Augspurger T,Dwyer J,Barnhart MC

更新日期：2009-11-01 00:00:00

abstract：:Fluvalinate has been extensively used in the United States to combat honey bee colony loss due to Varroa destructor mites. Our objectives were to investigate the extent of fluvalinate contamination in commercially available wax and to define exposure pathways to larval and adult honey bees. All the commercial wax test...

journal_title：Environmental toxicology and chemistry

authors： Fulton CA,Huff Hartz KE,Reeve JD,Lydy MJ

更新日期：2019-06-01 00:00:00