Effects analysis of time-varying or repeated exposures in aquatic ecological risk assessment of agrochemicals.

Abstract:

:Exposure to agrochemicals in the aquatic environment often occurs as time-varying or repeated pulses. Time-varying exposures may occur due to runoff events and spray drift associated with precipitation and application events. Hydrologic dilution, dispersion, and degradation also produce pulsed exposures. Standard laboratory toxicity tests using constant exposure concentrations typically do not investigate the toxicity of time-varying or repeated exposures. Detoxification, elimination, and recovery may occur within organisms or populations during the periods between exposures. The difficulty of estimating effects of realistic time-varying exposures from measurements made under constant exposure conditions is often an important source of uncertainty in ecological risk assessment of pesticides. This article discusses the criteria and tools for deciding whether time-varying exposures are relevant in a particular risk assessment, approaches for laboratory toxicity testing with time-varying exposure, modeling approaches for addressing effects oftime-varying exposure, deterministic and probabilistic ecological risk characterization of time-varyingexposures and toxicity, and uncertainty analysis.

journal_name

Environ Toxicol Chem

authors

Reinert KH,Giddings JM,Judd L

subject

Has Abstract

pub_date

2002-09-01 00:00:00

pages

1977-92

issue

9

eissn

0730-7268

issn

1552-8618

journal_volume

21

pub_type

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