In Vitro Biotransformation Assays Using Liver S9 Fractions and Hepatocytes from Rainbow Trout (Oncorhynchus mykiss): Overcoming Challenges with Difficult to Test Fragrance Chemicals.

abstract：:Ecological soil-screening levels (Eco-SSLs) were developed by the United States Environmental Protection Agency (USEPA) for the purposes of setting conservative soil screening values that can be used to eliminate the need for further ecological assessment for specific analytes at a given site. Ecological soil-screenin...

journal_title：Environmental toxicology and chemistry

authors： Sample BE,Fairbrother A,Kaiser A,Law S,Adams B

更新日期：2014-10-01 00:00:00

abstract：:The present study measured hepatic transcriptome responses in male rainbow darter (Etheostoma caeruleum) exposed to 2 municipal wastewater-treatment plants (MWWTPs; Kitchener and Waterloo) over 4 fall seasons (2011-2014) in the Grand River (Ontario, Canada). The overall goal was to determine if upgrades at the Kitchen...

journal_title：Environmental toxicology and chemistry

authors： Marjan P,Martyniuk CJ,Fuzzen MLM,MacLatchy DL,McMaster ME,Servos MR

更新日期：2017-08-01 00:00:00

abstract：:Linear alkylbenzene sulfonates (LAS) can be found in high concentrations in sewage sludge and, hence, may enter the soil compartment as a result of sludge application. Here, LAS may pose a risk for soil-dwelling organisms. In the present probabilistic risk assessment, statistical extrapolation has been used to assess ...

journal_title：Environmental toxicology and chemistry

authors： Jensen J,Løkke H,Holmstrup M,Krogh PH,Elsgaard L

更新日期：2001-08-01 00:00:00

abstract：:Polycyclic musks were measured in surface sediments collected from the Pearl River Delta and Macao coastal region, South China, to investigate contamination from domestic sewage. Three polycyclic musk compounds-4-acetyl-1,1-dimethyl-6-tert-butylindan, 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethylcyclopenta(g)-2-benzopy...

journal_title：Environmental toxicology and chemistry

authors： Zeng X,Mai B,Sheng G,Luo X,Shao W,An T,Fu J

更新日期：2008-01-01 00:00:00

abstract：:Dissolved organic carbon (DOC) plays a key role in determining the environmental fate of semivolatile organic environmental contaminants. The goal of the present study was to develop a method using commercially available hardware to rapidly characterize the sorption properties of DOC in water samples. The resulting me...

journal_title：Environmental toxicology and chemistry

authors： Ripszam M,Haglund P

更新日期：2015-02-01 00:00:00

abstract：:Soils and sediments in the floodplain of the Tittabawassee River downstream of Midland, Michigan, USA contain elevated concentrations of polychlorinated dibenzofurans (PCDF) and polychlorinated dibenzo-p-dioxins (PCDD). As a long-lived, resident top predator, the great horned owl (Bubo virginianus; GHO) has the potent...

journal_title：Environmental toxicology and chemistry

authors： Coefield SJ,Zwiernik MJ,Fredricks TB,Seston RM,Nadeau MW,Tazelaar DL,Moore JN,Kay DP,Roark SA,Giesy JP

更新日期：2010-10-01 00:00:00

abstract：:We evaluated the utility of gene-transcriptional responses in the liver of mosquitofish (Gambusia affinis), a species introduced to many countries and therefore widely available, for detecting endocrine-disrupting activity in water. Exposure to β-naphthoflavone, an aryl hydrocarbon receptor (AhR) agonist, significantl...

journal_title：Environmental toxicology and chemistry

authors： Kamata R,Itoh K,Nakajima D,Kageyama S,Sawabe A,Terasaki M,Shiraishi F

更新日期：2011-12-01 00:00:00

abstract：:The Minamata Convention aims to protect human health and the environment from anthropogenic emissions and releases of mercury. In the present study, the provisions of the Minamata Convention are examined to assess their influence on global biogeochemical cycling of Hg. Although the convention's scope covers all major ...

journal_title：Environmental toxicology and chemistry

authors： Selin NE

更新日期：2014-06-01 00:00:00

abstract：:To examine the behavior of the estrogenic biomarker vitellogenin (VTG) under the combined impact of estrogens and pathogens, parasite-infected or noninfected rainbow trout were exposed to two doses of 17β-estradiol (E2). Infected and E2-exposed fish showed significantly lower hepatic VTG mRNA levels than healthy fish....

journal_title：Environmental toxicology and chemistry

authors： Burki R,Krasnov A,Bettge K,Rexroad CE 3rd,Afanasyev S,Antikainen M,Burkhardt-Holm P,Wahli T,Segner H

更新日期：2012-10-01 00:00:00

abstract：:Luminescent bacterium Shk1 was created for the purpose of testing and screening the toxicity of activated sludge wastewater treatment plant influent to avoid toxic shock to the wastewater treatment plant microorganisms. The toxicity of a number of organic compounds was tested using an assay employing Shk1. Because the...

journal_title：Environmental toxicology and chemistry

authors： Ren S,Frymier PD

更新日期：2002-12-01 00:00:00

abstract：:Significant amounts of soil contaminated with polychlorinated biphenyls (PCBs) were discovered at a military radar station in Saglek Bay, Labrador, Canada, in 1996. Subsequent work showed elevated PCB concentrations in local marine sediments, in the benthic-associated food web, and in some ringed seals (Pusa hispida)....

journal_title：Environmental toxicology and chemistry

authors： Brown TM,Fisk AT,Helbing CC,Reimer KJ

更新日期：2014-03-01 00:00:00

abstract：:Excess selenium (Se) in the aquatic food chain is embryotoxic and teratogenic to avocets, stilts, and other waterbirds. American avocet (Recurvirostra americana) and black-necked stilt (Himantopus mexicanus) eggs were collected from three sites in the Tulare Lake Basin of California, USA, and hatched in the laboratory...

journal_title：Environmental toxicology and chemistry

authors： Hoffman DJ,Marn CM,Marois KC,Sproul E,Dunne M,Skorupa JP

更新日期：2002-03-01 00:00:00

abstract：:A population of western mosquitofish (Gambusia affinis) living below a wastewater treatment plant in the vicinity of Birmingham (AL, USA) was studied for evidence of exposure to estrogens. Mosquitofish are sexually dimorphic live-bearing fish. Males have an elongated and modified anal fin, called a gonopodium, used in...

journal_title：Environmental toxicology and chemistry

authors： Angus RA,Weaver SA,Grizzle JM,Watson RD

更新日期：2002-07-01 00:00:00

abstract：:The octanol-water partioning of inorganic mercury decreased with increasing sulfide, supporting a model that predicts decreased fractions of neutral Hg-S species with increasing sulfide. These results help explain the decreased availability of Hg to methylating bacteria under sulfidic conditions, and the inverse relat...

journal_title：Environmental toxicology and chemistry

authors： Benoit JM,Mason RP,Gilmour CC

更新日期：1999-10-01 00:00:00

abstract：:The aim of the present work was to study the effect of Cd2+ exposure on metallothionein (MT) induction and on the distribution of metals (Cd, Cu, and Zn) in the terrestrial pulmonate Helix aspersa. In particular, the soluble and nonsoluble pools of the accumulated metals and their tissue distribution in uncontaminated...

journal_title：Environmental toxicology and chemistry

authors： Hispard F,Schuler D,de Vaufleury A,Scheifler R,Badot PM,Dallinger R

更新日期：2008-07-01 00:00:00

abstract：:Hexanitrohexaazaisowurtzitane (CL-20), a new polycyclic polynitramine, has the same functional nitramine groups (N-NO2) as the widely used energetic chemicals hexahydro-1,3,5-trinitro-1,3,5-triazacyclohexane (royal demolition explosive [RDX]) and octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (high-melting explosive...

journal_title：Environmental toxicology and chemistry

authors： Dodard SG,Sunahara GI,Kuperman RG,Sarrazin M,Gong P,Ampleman G,Thiboutot S,Hawari J

更新日期：2005-10-01 00:00:00

abstract：:Blood samples from lizards (Gallotia galloti) collected from two agricultural areas (Las Galletas and Punta del Hidalgo) and two reference areas on the Island of Tenerife (Canary Islands, Spain) were analyzed for butyrylcholinesterase (BChE) activity. Serum BChE activity was characterized first by in vitro experiments...

journal_title：Environmental toxicology and chemistry

authors： Sanchez-Hernandez JC

更新日期：2003-02-01 00:00:00

abstract：:The toxicity and estrogenicity of a final treated municipal effluent was examined while flowing through a constructed wetland in north-central Texas, USA. Fish data were collected, and a baseline wetland characterization was performed to assess wetland treatment potential for these effluent properties. Vitellogenin (V...

journal_title：Environmental toxicology and chemistry

authors： Hemming JM,Waller WT,Chow MC,Denslow ND,Venables B

更新日期：2001-10-01 00:00:00

abstract：:The median 96-h lethal zinc concentration (LC50) was 439 microg Zn/L (hardness of 154 mg/L as CaCO3) for feral mottled sculpin (Cottus bairdi), decreasing to a median incipient lethal level of 266 microg Zn/L after 13 d. The 30-d chronic value was 255 microg Zn/L. The acute toxicity-hardness (ln-ln) slope of 1.022 exc...

journal_title：Environmental toxicology and chemistry

authors： Brinkman S,Woodling J

更新日期：2005-06-01 00:00:00

abstract：:Of the fish species tested in chronic Ni exposures, rainbow trout (Oncorhynchus mykiss) is the most sensitive. To develop additional Ni toxicity data and to investigate the toxic mode of action for Ni, we conducted acute (96-h) and chronic (85-d early life-stage) flow-through studies using rainbow trout. In addition t...

journal_title：Environmental toxicology and chemistry

authors： Brix KV,Keithly J,DeForest DK,Laughlin J

更新日期：2004-09-01 00:00:00

abstract：:This study evaluated the effects of dietary methylmercury (MeHg) on immune system development in captive-reared nestling American kestrels (Falco sparverius) to determine whether T cell-mediated and antibody-mediated adaptive immunity are targets for MeHg toxicity at environmentally relevant concentrations. Nestlings ...

journal_title：Environmental toxicology and chemistry

authors： Fallacara DM,Halbrook RS,French JB

更新日期：2011-06-01 00:00:00

abstract：:The effects of salinity, gender, and development on the acute toxicity of aldicarb were examined in the euryhaline fish, Japanese medaka (Oryzias latipes). The 96-h median lethal concentrations (LC50s) at 1.5 parts per thousand (per thousand) salinity were not significantly different between adults and juveniles but l...

journal_title：Environmental toxicology and chemistry

authors： El-Alfy AT,Grisle S,Schlenk D

更新日期：2001-09-01 00:00:00

abstract：:Physical impacts of diluted bitumen (dilbit) and the application of surface washing agents (SWAs) in freshwater have not been characterized for aquatic invertebrates. These compounds are known to reduce surface tension in feather and fur microstructures of birds and mammals, and thus likely to affect buoyancy of surfa...

journal_title：Environmental toxicology and chemistry

authors： Black TA,Hanson ML,Palace VP,Rodriguez-Gil JL

更新日期：2020-12-28 00:00:00

abstract：:In the present study, electron paramagnetic resonance coupled with spin-trapping technique was used, with alpha-phenyl-N-tert-butylnitrone (PBN) as a spin-trapping agent, to investigate free radical generation in freshwater fish with acute 2,4-dichlorophenol (2,4-DCP) poisoning. The PBN-radical adducts were detected i...

journal_title：Environmental toxicology and chemistry

authors： Luo Y,Wang XR,Shi HH,Mao DQ,Sui YX,Ji LL

更新日期：2005-09-01 00:00:00

abstract：:The risk assessment of nanomaterials is essential for regulatory purposes and for sustainable nanotechnological development. Although the application of graphene oxide has been widely exploited, its environmental risk is not well understood because several environmental conditions can affect its behavior and toxicity....

journal_title：Environmental toxicology and chemistry

authors： Castro VL,Clemente Z,Jonsson C,Silva M,Vallim JH,de Medeiros AMZ,Martinez DST

更新日期：2018-07-01 00:00:00

abstract：:A method is proposed for estimating metabolic biotransformation rate constants for nonionic organic chemicals from measured laboratory bioconcentration and dietary bioaccumulation data in fish. Data have been selected based on a quality review to reduce uncertainty in the measured values. A kinetic mass balance model ...

journal_title：Environmental toxicology and chemistry

authors： Arnot JA,Mackay D,Bonnell M

更新日期：2008-02-01 00:00:00

abstract：:The present review describes and discusses key interactions between mercury (Hg) and phytoplankton to highlight the role of phytoplankton in the biogeochemical cycle of Hg and to understand direct or indirect Hg effects on phytoplankton. Phytoplankton are exposed to various Hg species in surface waters. Through Hg upt...

journal_title：Environmental toxicology and chemistry

authors： Le Faucheur S,Campbell PG,Fortin C,Slaveykova VI

更新日期：2014-06-01 00:00:00

abstract：:New techniques and software have enabled ubiquitous use of structure-activity relationships (SARs) in the pharmaceutical industry and toxicological sciences. We review the status of SAR technology by using examples to underscore the advances as well as the unique technical challenges. Applying SAR involves two steps: ...

journal_title：Environmental toxicology and chemistry

authors： Tong W,Welsh WJ,Shi L,Fang H,Perkins R

更新日期：2003-08-01 00:00:00

abstract：:A market for bisphenol A (BPA) replacement compounds has emerged due to restrictions on the use of BPA. Some of these compounds were detected in the environment, yet little is known about their toxicological properties. In the present study, an avian in vitro toxicogenomic approach was used to compare the effects of f...

journal_title：Environmental toxicology and chemistry

authors： Sharin T,Williams KL,Chiu S,Crump D,O'Brien JM

更新日期：2021-01-19 00:00:00

abstract：:Field populations of aquatic organisms, particularly those inhabiting flowing waters, likely are exposed to short pulses of pesticides following periods of spray drift, surface runoff, or drain flow. In the present study, we investigated the effect of pulse exposures of a pyrethroid insecticide, esfenvalerate, on surv...

journal_title：Environmental toxicology and chemistry

authors： Forbes VE,Cold A

更新日期：2005-01-01 00:00:00