Pathogenic infection confounds induction of the estrogenic biomarker vitellogenin in rainbow trout.

Abstract:

:To examine the behavior of the estrogenic biomarker vitellogenin (VTG) under the combined impact of estrogens and pathogens, parasite-infected or noninfected rainbow trout were exposed to two doses of 17β-estradiol (E2). Infected and E2-exposed fish showed significantly lower hepatic VTG mRNA levels than healthy fish. Transcriptome data suggest that this was due to energetic constraints. Reduced responsiveness of the VTG biomarker in parasitized fish might obscure detection of low-level field exposure.

journal_name

Environ Toxicol Chem

authors

Burki R,Krasnov A,Bettge K,Rexroad CE 3rd,Afanasyev S,Antikainen M,Burkhardt-Holm P,Wahli T,Segner H

doi

10.1002/etc.1966

subject

Has Abstract

pub_date

2012-10-01 00:00:00

pages

2318-23

issue

10

eissn

0730-7268

issn

1552-8618

journal_volume

31

pub_type

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