Chemerin is a novel regulator of lactogenesis in bovine mammary epithelial cells.

abstract：:To investigate involvement of miRNAs in radiation responses we used microRNAome profiling to analyze the sex-specific response of radiation sensitive hematopoietic lymphoid tissues. We show that radiation exposure resulted in a significant and sex-specific deregulation of microRNA expression in murine spleen and thymu...

journal_title：Biochemical and biophysical research communications

authors： Ilnytskyy Y,Zemp FJ,Koturbash I,Kovalchuk O

更新日期：2008-12-05 00:00:00

abstract：:Intestinal N-acetylglucosamine 6-O-sulfotransferase (I-GlcNAc6ST, GST-4alpha) and corneal N-acetylglucosamine 6-O-sulfotransferases (C-GlcNAc6ST, GST-4beta) are two highly homologous GlcNAc 6-O-sulfotransferase isozymes encoded by two intronless open reading frames that reside approximately 50 kb apart on human chromo...

journal_title：Biochemical and biophysical research communications

authors： Bartes A,Bhakta S,Hemmerich S

更新日期：2001-04-13 00:00:00

abstract：:The precursor of amphibian tachykinin has not been found although more than 30 tachykinins have been isolated from amphibians since 1964. In this report, two tachykinin-like peptides are identified from the skin secretions of the frog, Odorrana grahami. Their amino acid sequences are DDTEDLANKFIGLM-NH(2) (named tachyk...

journal_title：Biochemical and biophysical research communications

authors： Li J,Liu T,Xu X,Wang X,Wu M,Yang H,Lai R

更新日期：2006-12-01 00:00:00

abstract：:Autophagy is a tightly regulated self-digestion system. As in other cell types, autophagy plays an essential role in the homeostasis of pancreatic beta cells. However, the mechanisms involved in the deterioration of beta cell function caused by autophagic failure have not yet been fully elucidated. To gain insight int...

journal_title：Biochemical and biophysical research communications

authors： Yamamoto E,Uchida T,Abe H,Taka H,Fujimura T,Komiya K,Hara A,Ogihara T,Fujitani Y,Ueno T,Takeda S,Watada H

更新日期：2014-10-10 00:00:00

abstract：:We previously showed that SIRT1 deacetylase inhibits proliferation of hepatocellular carcinoma cells expressing hepatitis B virus (HBV) X protein (HBX), by destabilization of β-catenin. Here, we report another role for SIRT1 in HBX-mediated resistance to oxidative stress. Ectopic expression and enhanced activity of SI...

journal_title：Biochemical and biophysical research communications

authors： Srisuttee R,Koh SS,Malilas W,Moon J,Cho IR,Jhun BH,Horio Y,Chung YH

更新日期：2012-12-07 00:00:00

abstract：:We investigated the molecular effect and signal pathway of icariin, a major flavonoid of Epimedium koreanum Nakai, on angiogenesis. Icariin stimulated in vitro endothelial cell proliferation, migration, and tubulogenesis, which are typical phenomena of angiogenesis, as well as increased in vivo angiogenesis. Icariin a...

journal_title：Biochemical and biophysical research communications

authors： Chung BH,Kim JD,Kim CK,Kim JH,Won MH,Lee HS,Dong MS,Ha KS,Kwon YG,Kim YM

更新日期：2008-11-14 00:00:00

abstract：:The effect of phosphorylation of calcineurin on calmodulin (CaM) binding was examined using a synthetic peptide which contains the CaM-binding domain and the serine phosphorylation site. The peptide, corresponding to residues 391-414 of brain calcineurin A subunit, was rapidly phosphorylated by protein kinase C and Ca...

journal_title：Biochemical and biophysical research communications

authors： Calalb MB,Kincaid RL,Soderling TR

更新日期：1990-10-30 00:00:00

abstract：:Compounds that block angiogenesis are effective in the treatment of certain cancers and other angiogenesis-related diseases. Many of these compounds specifically target the rapidly proliferating and migrating endothelial cell. However, angiogenesis is a multi-faceted process involving heterotypic interactions between ...

journal_title：Biochemical and biophysical research communications

authors： Dudley A,Gilbert RE,Thomas D,Cox A,Price JT,Best J,Jenkins A

更新日期：2003-10-10 00:00:00

abstract：:RNA extracts from the isthmus of laying hen oviduct contain truncated 5S RNA molecules that were found to be shorter at their 5' terminus as compared to native 5S RNA I and II. Moreover one of the truncated species differs from 5S RNA I by the absence of the 3' end nucleotide. The truncated forms increase of about 70%...

journal_title：Biochemical and biophysical research communications

authors： Keith G,Nys Y,Fix C,Heyman T

更新日期：1986-08-14 00:00:00

abstract：:The isolation of human adrenal capillary endothelial (HACE) cells without resort to fluorescence activated cell sorting is described, together with their properties in culture. HACE cells were isolated by plating collagenase digests at high dilution in the presence of endothelial cell growth supplement, followed by cl...

journal_title：Biochemical and biophysical research communications

authors： Fawcett J,Harris AL,Bicknell R

更新日期：1991-01-31 00:00:00

abstract：:Using circular dichroism, fluorescence, and infrared spectroscopies, we studied the secondary structure of purified hamster PrP(C) in the presence of the mild, nonionic detergent octylglucoside. Under these native conditions, PrP(C) displayed an unexpectedly high beta-sheet component, intermediate between the values p...

journal_title：Biochemical and biophysical research communications

authors： Pergami P,Bramanti E,Ascoli GA

更新日期：1999-11-02 00:00:00

abstract：:The hepatocytes were cultivated in the presence of lithium carbonate (LC) for drugs testing or possible source for transplantation in the treatment of hereditary or terminal liver diseases. The LC, as an inducer of autophagy, is a promising drug for maintaining cell homeostasis and has a significant effect on the ultr...

journal_title：Biochemical and biophysical research communications

authors： Dossymbekova R,Bgatova N,Tungushbayeva Z,Sharipov K,Taneyeva G,Kydyrbaeva A,Solovieva A

更新日期：2020-07-23 00:00:00

abstract：:Heavy water (D2O) has been used as a putative inhibitor of the plasma membrane H(+)-ATPase and the plasma membrane redox system. Concentrations above 50% D2O inhibited H+ secretion and the plasma membrane redox system of Zea mays L. roots. Inhibition of H+ secretion by vanadate was reduced in presence of D2O. The plas...

journal_title：Biochemical and biophysical research communications

authors： Döring O,Böttger M

更新日期：1992-01-31 00:00:00

abstract：:The filamentous fungus Aspergillus ochraceus TS produces an inducible microsomal cytochrome P-450 linked monooxygenase which is capable of hydroxylating benzo(a)pyrene in presence of O2 and NADPH. The addition of Benzo(a)pyrene, 3-Methyl cholanthrene, beta-Naphthoflavone and other aryl hydrocarbons during the inductio...

journal_title：Biochemical and biophysical research communications

authors： Dutta D,Ghosh DK,Mishra AK,Samanta TB

更新日期：1983-09-15 00:00:00

abstract：:P19 embryonal carcinoma (EC) cells are pluripotent stem cells and have numerous morphological and biochemical properties in common with embryonic stem (ES) cells. However, P19 cells differentiate very ineffectively as embryoid bodies (EBs) without the specific chemical inducers whereas ES cells exhibit spontaneous dif...

journal_title：Biochemical and biophysical research communications

authors： Morikawa K,Ikeda N,Hisatome I,Shirayoshi Y

更新日期：2013-02-08 00:00:00

abstract：:Numerous synthetic chemicals have estrogenic activity by interacting with the estrogen receptor. In this report, we test the hypothesis that some estrogenic chemicals may also modulate the human progesterone receptor (hPR) signaling pathway. This was evaluated by examining synthetic chemicals for their ability to modu...

journal_title：Biochemical and biophysical research communications

authors： Tran DQ,Klotz DM,Ladlie BL,Ide CF,McLachlan JA,Arnold SF

更新日期：1996-12-13 00:00:00

abstract：:Breath isoprene accounts for most of the hydrocarbon removal via exhalation and is thought to serve as a non-invasive indicator for assaying several metabolic effects in the human body. The primary objective of this paper is to introduce a novel working hypothesis with respect to the endogenous source of this compound...

journal_title：Biochemical and biophysical research communications

authors： King J,Mochalski P,Unterkofler K,Teschl G,Klieber M,Stein M,Amann A,Baumann M

更新日期：2012-07-06 00:00:00

abstract：:The envelope glycoprotein E2 is the major immunodominant protein of the classical swine fever virus and can induce neutralizing antibodies and protective host-immune responses in infected swine. We designed, expressed, and purified multi-epitope protein (GST-BT22) that contains a tandem repeat of the E2 antigenic-dete...

journal_title：Biochemical and biophysical research communications

authors： Tian H,Hou X,Liu X

更新日期：2013-02-08 00:00:00

abstract：:Reoxidation of the reduced insulin A and B chains in 8 M urea leads to a recovery of native insulin of 2-7% whereas in 6 M guanidine or 0.5 mM dodecylsulfate very little, if any, resynthesis of insulin could be detected. Considering all the possibilities of different oligomeric forms containing one or both of the chai...

journal_title：Biochemical and biophysical research communications

authors： Qian YQ,Tsou CL

更新日期：1987-07-31 00:00:00

abstract：:Hyperphosphorylation of extracellular signal-regulated protein kinases-1/2 (ERK1/2) is known to promote cancer cell proliferation. We therefore investigated the constitutive phosphorylation levels of ERK1/2 and the expression of its downstream targets c-Fos, c-Jun, and cyclooxygenase-2 (COX-2) in biopsied human gastri...

journal_title：Biochemical and biophysical research communications

authors： Wu WK,Sung JJ,Yu L,Li ZJ,Chu KM,Cho CH

更新日期：2008-08-22 00:00:00

abstract：:Protein kinase C (PKC) and the GTPase-activating protein GAP can be detected in immunoprecipitates of mouse epidermis and lung cytosol obtained with either anti-GAP or anti-PKC antisera. The PKC in the immune-complex phosphorylates the coprecipitated GAP protein. Moreover, purified recombinant GAP is phosphorylated in...

journal_title：Biochemical and biophysical research communications

authors： Gschwendt M,Kittstein W,Marks F

更新日期：1993-07-15 00:00:00

abstract：:Individual yeast colonies produce pulses of volatile ammonia separated by phases of medium acidification. Colonies of Saccharomyces cerevisiae mutant defective in the general amino acid permease, Gap1p, exhibit decreased ammonia production. Mutations in the S. cerevisiae amino acid sensor SPS completely abolish the co...

journal_title：Biochemical and biophysical research communications

authors： Zikánová B,Kuthan M,Ricicová M,Forstová J,Palková Z

更新日期：2002-06-28 00:00:00

abstract：:Free radicals attack lipid molecules and initiate a chain of reactions that may trigger several diseases such as atherosclerosis and cancer. Several markers of oxidative stress have been proposed, including measurements of lipid peroxides and short-chain aldehydes levels and evaluation of conjugated diene formation. A...

journal_title：Biochemical and biophysical research communications

authors： Visioli F,Colombo C,Galli C

更新日期：1998-04-17 00:00:00

abstract：:2'-Deoxycoformycin (dCF), a specific and potent inhibitor of adenosine deaminase, has demonstrated significant antitumor effect on lymphoid malignancies. The drug induced functional and morphologic differentiation of myeloid leukemia cells in combination with 2'-deoxyadenosine (dAd), but not dCF alone. NB4, a cell lin...

journal_title：Biochemical and biophysical research communications

authors： Niitsu N,Umeda M,Honma Y

更新日期：1997-09-08 00:00:00

abstract：:Nonalcoholic fatty liver disease (NAFLD) is featured by hepatic steatosis, insulin resistance, lipid deposition and inflammation. However, the pathogenic mechanism of NAFLD is still poorly understood. Dual-specificity phosphatase 16 (DUSP16), a c-Jun N-terminal kinase-specific phosphatase, has been reported to negativ...

journal_title：Biochemical and biophysical research communications

authors： Wu YK,Hu LF,Lou DS,Wang BC,Tan J

更新日期：2020-03-26 00:00:00

abstract：:The fate of [125I] lactoferrin after binding on its specific receptor on HT29-D4 cells, a clone of HT29 cells, was studied and compared with that of [125I]transferrin. Time courses of protein binding in relation with temperature clearly show that different mechanisms of ligand-transportation for the two glycoproteins ...

journal_title：Biochemical and biophysical research communications

authors： Roiron-Lagroux D,Figarella C

更新日期：1990-07-31 00:00:00

abstract：:Hop/STI1 is a co-chaperone adaptor protein for Hsp70/Hsp90 complexes. Hop/STI1 is found extracellularly and modulates cell death and differentiation through interaction with the prion protein (PrP(C)). Here, we investigated the expression of hop/STI1 and its role upon cell proliferation and cell death in the developin...

journal_title：Biochemical and biophysical research communications

authors： Arruda-Carvalho M,Njaine B,Silveira MS,Linden R,Chiarini LB

更新日期：2007-09-21 00:00:00

abstract：:Among the members of the additional sex comb-like (ASXL) family, ASXL3 remains unexplored. Here, we showed that ASXL3 interacts with HP1α and LSD1, leading to transcriptional repression. We determined that ASXL3 depletion augments the ligand-induced transcriptional activities of LXRα and TRβ, which were repressed by A...

journal_title：Biochemical and biophysical research communications

authors： Shin N,Lee YK,Park UH,Jeong JC,Um SJ

更新日期：2014-11-28 00:00:00

abstract：:The hydrolysis of sphingomyelin in cells derived from a Niemann-Pick patient was studied using both a labelled precursor and measurement of endogenous levels. In vitro exposure of the cells to cannabidiol resulted in a large decrease in both the relative and absolute amounts of this lipid; the drug had a smaller effec...

journal_title：Biochemical and biophysical research communications

authors： Burstein S,Hunter SA,Renzulli L

更新日期：1984-05-31 00:00:00

abstract：:Staphylococcus aureus and Escherichia coli sensitive to chloramphenicol incubated with this antibiotic suffered oxidative stress with increase of anion superoxide (O2-). This reactive species of oxygen was detected by chemiluminescence with lucigenin. S. aureus, E. coli, and Enterococcus faecalis sensitive to ciproflo...

journal_title：Biochemical and biophysical research communications

authors： Albesa I,Becerra MC,Battán PC,Páez PL

更新日期：2004-04-30 00:00:00