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Heart and liver transplantation. Consistent survival after prolonged donor heart preservation.

Abstract：

:Twelve dogs underwent orthotopic cardiac transplantation after donor heart preservation for 24 hr in a hypothermic hypertonic intracellular solution. Donors were divided into two groups: continuous oxygenated perfusion and nonperfusion. After 24 hr, transplantation was performed. All six perfused and four nonperfused donors hearts survived a 24-hr postoperative period. Survivors had normal cardiac output, right and left atrial pressures, and aortic pressures. After transplantation, all perfused hearts demonstrated mild left ventricular damage while nonperfused hearts had severe damage. Hypothermic hypertonic intracellular perfusion may allow improved protection for short-term myocardial preservation and survival after extended myocardial preservation.

journal_name

Transplant Proc

journal_title

Transplantation proceedings

authors

Watson DC Jr

subject

Has Abstract

pub_date

1977-03-01 00:00:00

pages

297-9

issue

1

eissn

0041-1345

issn

1873-2623

journal_volume

9

pub_type

杂志文章

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